Elena Maspero

Elena Maspero

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Elena Maspero

Elena Maspero

Publications by authors named "Elena Maspero"

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Detection of ubiquitinated targets in mammalian and Drosophila models.

Methods Enzymol 2019 11;619:293-318. Epub 2019 Feb 11.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy; Dipartimento di oncologia ed emato-oncologia, Universita' degli Studi di Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/bs.mie.2018.12.030DOI Listing
February 2020

Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling.

Cell Rep 2019 06;27(10):3049-3061.e6

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy; Istituto Europeo di Oncologia IRCCS, Via Ripamonti 435, 20141 Milan, Italy; Università degli Studi di Milano, Dipartimento di Oncologia ed Emato-oncologia, Via Santa Sofia 9/1, 20122 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.05.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581797PMC
June 2019

HECT E3 Ligases: A Tale With Multiple Facets.

Front Physiol 2019 3;10:370. Epub 2019 Apr 3.

Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.

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http://dx.doi.org/10.3389/fphys.2019.00370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457168PMC
April 2019

β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.

J Mol Biol 2018 09 28;430(18 Pt B):3218-3233. Epub 2018 Jun 28.

Max Planck Institute for Developmental Biology, Max-Planck-Ring 5, 72076 Tübingen, Germany; Institute of Biophysics and Physical Biochemistry, University of Regensburg, Universitätsstr. 31, 93040 Regensburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.06.044DOI Listing
September 2018

In Vitro Ubiquitination: Self-Ubiquitination, Chain Formation, and Substrate Ubiquitination Assays.

Methods Mol Biol 2016 ;1449:153-60

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, Milan, 20139, Italy.

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http://dx.doi.org/10.1007/978-1-4939-3756-1_7DOI Listing
January 2018

Targeting HECT-type E3 ligases - insights from catalysis, regulation and inhibitors.

FEBS Lett 2017 09 20;591(17):2636-2647. Epub 2017 Aug 20.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.

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http://dx.doi.org/10.1002/1873-3468.12775DOI Listing
September 2017

USP9X Controls EGFR Fate by Deubiquitinating the Endocytic Adaptor Eps15.

Curr Biol 2016 Jan 31;26(2):173-183. Epub 2015 Dec 31.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy; DIPO, Dipartimento di Oncologia ed Emato-Oncologia, Università degli Studi di Milano, Via di Rudinì 8, 20122 Milan, Italy. Electronic address:

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http://www.cell.com/current-biology/pdf/S0960-9822(15)01489-
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http://linkinghub.elsevier.com/retrieve/pii/S096098221501489
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http://dx.doi.org/10.1016/j.cub.2015.11.050DOI Listing
January 2016

Structural and functional framework for the autoinhibition of Nedd4-family ubiquitin ligases.

Structure 2014 Nov 30;22(11):1639-49. Epub 2014 Oct 30.

Max Planck Institute for Developmental Biology, Spemannstrasse 35, 72076 Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.str.2014.09.006DOI Listing
November 2014

Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity.

Sci Signal 2014 Oct 7;7(346):ra95. Epub 2014 Oct 7.

Cell Biology Program, The Hospital for Sick Children, and Biochemistry Department, University of Toronto, 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.

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http://dx.doi.org/10.1126/scisignal.2005290DOI Listing
October 2014

The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation.

J Lipid Res 2013 Aug 3;54(8):2174-84. Epub 2013 Jun 3.

Department of Medical Biochemistry, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1194/jlr.M037713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3708367PMC
August 2013

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming.

Nat Struct Mol Biol 2013 Jun 5;20(6):696-701. Epub 2013 May 5.

Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.

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http://dx.doi.org/10.1038/nsmb.2566DOI Listing
June 2013

A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase.

Cell Cycle 2012 Jul 1;11(13):2538-44. Epub 2012 Jul 1.

Department of Pharmaceutical Sciences, University of Piemonte Orientale "A. Avogadro", Novara, Italy.

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http://dx.doi.org/10.4161/cc.20919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404880PMC
July 2012

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation.

EMBO Rep 2011 Apr 11;12(4):342-9. Epub 2011 Mar 11.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Istituto Europeo di Oncologia, Via Adamello 16, Milan 20139, Italy.

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http://dx.doi.org/10.1038/embor.2011.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3077247PMC
April 2011

Molecular mechanisms of coupled monoubiquitination.

Nat Cell Biol 2006 Nov 1;8(11):1246-54. Epub 2006 Oct 1.

IFOM, The FIRC Institute for Molecular Oncology, Via Adamello 16, 20139, Milan, Italy.

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http://dx.doi.org/10.1038/ncb1484DOI Listing
November 2006

Clathrin-independent endocytosis of ubiquitinated cargos.

Proc Natl Acad Sci U S A 2005 Feb 8;102(8):2760-5. Epub 2005 Feb 8.

Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy.

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http://dx.doi.org/10.1073/pnas.0409817102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC549482PMC
February 2005