Elena Helman

Elena Helman

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Elena Helman

Elena Helman

Publications by authors named "Elena Helman"

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Reversion Mutations in Circulating Tumor DNA Predict Primary and Acquired Resistance to the PARP Inhibitor Rucaparib in High-Grade Ovarian Carcinoma.

Authors:
Kevin K Lin Maria I Harrell Amit M Oza Ana Oaknin Isabelle Ray-Coquard Anna V Tinker Elena Helman Marc R Radke Carmen Say Lan-Thanh Vo Elaina Mann Jeffrey D Isaacson Lara Maloney David M O'Malley Setsuko K Chambers Scott H Kaufmann Clare L Scott Gottfried E Konecny Robert L Coleman James X Sun Heidi Giordano James D Brenton Thomas C Harding Iain A McNeish Elizabeth M Swisher

Cancer Discov 2019 02 13;9(2):210-219. Epub 2018 Nov 13.

Division of Gynecologic Oncology, University of Washington, Seattle, Washington.

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http://cancerdiscovery.aacrjournals.org/lookup/doi/10.1158/2
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http://dx.doi.org/10.1158/2159-8290.CD-18-0715DOI Listing
February 2019

Cell-Free DNA Next-Generation Sequencing Prediction of Response and Resistance to Third-Generation EGFR Inhibitor.

Authors:
Elena Helman Minh Nguyen Chris A Karlovich Darrin Despain A Karin Choquette Alexander I Spira Helena A Yu D Ross Camidge Thomas C Harding Richard B Lanman Andrew D Simmons

Clin Lung Cancer 2018 11 7;19(6):518-530.e7. Epub 2018 Aug 7.

Clovis Oncology Inc, Boulder, CO.

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https://linkinghub.elsevier.com/retrieve/pii/S15257304183019
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http://dx.doi.org/10.1016/j.cllc.2018.07.008DOI Listing
November 2018

Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma.

Authors:
Jennifer A Perry Adam Kiezun Peter Tonzi Eliezer M Van Allen Scott L Carter Sylvan C Baca Glenn S Cowley Ami S Bhatt Esther Rheinbay Chandra Sekhar Pedamallu Elena Helman Amaro Taylor-Weiner Aaron McKenna David S DeLuca Michael S Lawrence Lauren Ambrogio Carrie Sougnez Andrey Sivachenko Loren D Walensky Nikhil Wagle Jaume Mora Carmen de Torres Cinzia Lavarino Simone Dos Santos Aguiar Jose Andres Yunes Silvia Regina Brandalise Gabriela Elisa Mercado-Celis Jorge Melendez-Zajgla Rocío Cárdenas-Cardós Liliana Velasco-Hidalgo Charles W M Roberts Levi A Garraway Carlos Rodriguez-Galindo Stacey B Gabriel Eric S Lander Todd R Golub Stuart H Orkin Gad Getz Katherine A Janeway

Proc Natl Acad Sci U S A 2014 Dec 15;111(51):E5564-73. Epub 2014 Dec 15.

Department of Pediatric Oncology, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA 02215; Department of Pediatrics,

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http://dx.doi.org/10.1073/pnas.1419260111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280630PMC
December 2014

Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing.

Authors:
Elena Helman Michael S Lawrence Chip Stewart Carrie Sougnez Gad Getz Matthew Meyerson

Genome Res 2014 Jul 13;24(7):1053-63. Epub 2014 May 13.

Harvard-MIT Division of Health Sciences & Technology, Cambridge, Massachusetts 02139, USA; Broad Institute of MIT and Harvard, Cambridge, Masachusetts 02142, USA; Center for Cancer Genome Discovery and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA; Department of Pathology, Brigham & Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1101/gr.163659.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079962PMC
July 2014

Mutational heterogeneity in cancer and the search for new cancer-associated genes.

Authors:
Michael S Lawrence Petar Stojanov Paz Polak Gregory V Kryukov Kristian Cibulskis Andrey Sivachenko Scott L Carter Chip Stewart Craig H Mermel Steven A Roberts Adam Kiezun Peter S Hammerman Aaron McKenna Yotam Drier Lihua Zou Alex H Ramos Trevor J Pugh Nicolas Stransky Elena Helman Jaegil Kim Carrie Sougnez Lauren Ambrogio Elizabeth Nickerson Erica Shefler Maria L Cortés Daniel Auclair Gordon Saksena Douglas Voet Michael Noble Daniel DiCara Pei Lin Lee Lichtenstein David I Heiman Timothy Fennell Marcin Imielinski Bryan Hernandez Eran Hodis Sylvan Baca Austin M Dulak Jens Lohr Dan-Avi Landau Catherine J Wu Jorge Melendez-Zajgla Alfredo Hidalgo-Miranda Amnon Koren Steven A McCarroll Jaume Mora Brian Crompton Robert Onofrio Melissa Parkin Wendy Winckler Kristin Ardlie Stacey B Gabriel Charles W M Roberts Jaclyn A Biegel Kimberly Stegmaier Adam J Bass Levi A Garraway Matthew Meyerson Todd R Golub Dmitry A Gordenin Shamil Sunyaev Eric S Lander Gad Getz

Nature 2013 Jul 16;499(7457):214-218. Epub 2013 Jun 16.

The Broad Institute of MIT and Harvard, Cambridge, MA, 02141, USA.

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https://dash.harvard.edu/bitstream/handle/1/11879842/3919509
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http://www.nature.com/doifinder/10.1038/nature12213
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http://dx.doi.org/10.1038/nature12213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919509PMC
July 2013

Absolute quantification of somatic DNA alterations in human cancer.

Authors:
Scott L Carter Kristian Cibulskis Elena Helman Aaron McKenna Hui Shen Travis Zack Peter W Laird Robert C Onofrio Wendy Winckler Barbara A Weir Rameen Beroukhim David Pellman Douglas A Levine Eric S Lander Matthew Meyerson Gad Getz

Nat Biotechnol 2012 May;30(5):413-21

The Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.

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http://www.nature.com/articles/nbt.2203
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http://dx.doi.org/10.1038/nbt.2203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383288PMC
May 2012

A geometric approach for classification and comparison of structural variants.

Authors:
Suzanne Sindi Elena Helman Ali Bashir Benjamin J Raphael

Bioinformatics 2009 Jun;25(12):i222-30

Division of Applied Mathematics, Center for Computational Molecular Biology, Brown University, Providence, RI, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/btp208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2687962PMC
June 2009