Publications by authors named "Eleazar Eskin"

100Publications

Genetic Determinants of Ammonia-Induced Acute Lung Injury in Mice.

Am J Physiol Lung Cell Mol Physiol 2020 Oct 14. Epub 2020 Oct 14.

Envirionmental and Occupational Health, University of Pittsburgh, United States.

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http://dx.doi.org/10.1152/ajplung.00276.2020DOI Listing
October 2020

Metalign: efficient alignment-based metagenomic profiling via containment min hash.

Genome Biol 2020 Sep 10;21(1):242. Epub 2020 Sep 10.

Department of Clinical Pharmacy, University of Southern California, Los Angeles, CA, 90089, USA.

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http://dx.doi.org/10.1186/s13059-020-02159-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7488264PMC
September 2020

Correction to: Improving the usability and comprehensiveness of microbial databases.

BMC Biol 2020 07 28;18(1):92. Epub 2020 Jul 28.

Department of Clinical Pharmacy, University of Southern California School of Pharmacy, 1985 Zonal Ave, Los Angeles, CA, 90089, USA.

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http://dx.doi.org/10.1186/s12915-020-00831-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7389812PMC
July 2020

Improving the usability and comprehensiveness of microbial databases.

BMC Biol 2020 04 7;18(1):37. Epub 2020 Apr 7.

Department of Clinical Pharmacy, University of Southern California School of Pharmacy, 1985 Zonal Ave, Los Angeles, CA, 90089, USA.

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http://dx.doi.org/10.1186/s12915-020-0756-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7140547PMC
April 2020

A Unifying Framework for Imputing Summary Statistics in Genome-Wide Association Studies.

J Comput Biol 2020 03 13;27(3):418-428. Epub 2020 Feb 13.

Department of Computer Science, University of California, Los Angeles, Los Angeles.

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http://dx.doi.org/10.1089/cmb.2019.0449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081249PMC
March 2020

A GWAS approach identifies Dapp1 as a determinant of air pollution-induced airway hyperreactivity.

PLoS Genet 2019 12 23;15(12):e1008528. Epub 2019 Dec 23.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944376PMC
December 2019

Leveraging allelic imbalance to refine fine-mapping for eQTL studies.

PLoS Genet 2019 12 13;15(12):e1008481. Epub 2019 Dec 13.

Computer Science Department, University of California Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952111PMC
December 2019

Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage.

Nat Neurosci 2019 09 26;22(9):1521-1532. Epub 2019 Aug 26.

Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

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http://www.nature.com/articles/s41593-019-0461-9
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http://dx.doi.org/10.1038/s41593-019-0461-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750256PMC
September 2019

A linear mixed model approach to gene expression-tumor aneuploidy association studies.

Sci Rep 2019 08 16;9(1):11944. Epub 2019 Aug 16.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41598-019-48302-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697733PMC
August 2019

Cell-type-specific resolution epigenetics without the need for cell sorting or single-cell biology.

Nat Commun 2019 07 31;10(1):3417. Epub 2019 Jul 31.

Department of Computer Science, University of California, Los Angeles, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1038/s41467-019-11052-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668473PMC
July 2019

MiCoP: microbial community profiling method for detecting viral and fungal organisms in metagenomic samples.

BMC Genomics 2019 Jun 6;20(Suppl 5):423. Epub 2019 Jun 6.

Department of Computer Science, University of California, Los Angeles, 90095, CA, USA.

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http://dx.doi.org/10.1186/s12864-019-5699-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551237PMC
June 2019

Systematic benchmarking of omics computational tools.

Nat Commun 2019 03 27;10(1):1393. Epub 2019 Mar 27.

Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1038/s41467-019-09406-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437167PMC
March 2019

Improving the usability and archival stability of bioinformatics software.

Genome Biol 2019 02 27;20(1):47. Epub 2019 Feb 27.

Department of Genetics, Cell Biology and Development, University of Minnesota, 321 Church St SE, Minneapolis, MN, 55455, USA.

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http://dx.doi.org/10.1186/s13059-019-1649-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391762PMC
February 2019

Population structure in genetic studies: Confounding factors and mixed models.

PLoS Genet 2018 12 27;14(12):e1007309. Epub 2018 Dec 27.

Department of Computer Science, University of California, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307707PMC
December 2018

Word and Sentence Embedding Tools to Measure Semantic Similarity of Gene Ontology Terms by Their Definitions.

J Comput Biol 2019 01 31;26(1):38-52. Epub 2018 Oct 31.

2 Department of Human Genetics, and University of California, Los Angeles, California.

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https://www.liebertpub.com/doi/10.1089/cmb.2018.0093
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http://dx.doi.org/10.1089/cmb.2018.0093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350067PMC
January 2019

Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies.

J Comput Biol 2019 11 1;26(11):1203-1213. Epub 2018 Oct 1.

Department of Computer Science, University of California Los Angeles, Los Angeles, California.

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https://www.liebertpub.com/doi/10.1089/cmb.2018.0139
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http://dx.doi.org/10.1089/cmb.2018.0139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856942PMC
November 2019

Finding associated variants in genome-wide association studies on multiple traits.

Bioinformatics 2018 07;34(13):i467-i474

Department of Computer Science, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022769PMC
July 2018

An Association Mapping Framework To Account for Potential Sex Difference in Genetic Architectures.

Genetics 2018 07 11;209(3):685-698. Epub 2018 May 11.

Department of Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea

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http://dx.doi.org/10.1534/genetics.117.300501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028251PMC
July 2018

Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia.

Transl Psychiatry 2018 05 10;8(1):96. Epub 2018 May 10.

Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University California Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41398-018-0107-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943399PMC
May 2018

Involving undergraduates in genomics research to narrow the education-research gap.

Nat Biotechnol 2018 04;36(4):369-371

Department of Computer Science, University of California, Los Angeles, Los Angeles, California, USA.

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http://www.nature.com/doifinder/10.1038/nbt.4113
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http://dx.doi.org/10.1038/nbt.4113DOI Listing
April 2018

An ancestry-based approach for detecting interactions.

Genet Epidemiol 2018 02 8;42(1):49-63. Epub 2017 Nov 8.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1002/gepi.22087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065511PMC
February 2018

Addressing the Digital Divide in Contemporary Biology: Lessons from Teaching UNIX.

Trends Biotechnol 2017 10 15;35(10):901-903. Epub 2017 Jul 15.

Department of Computer Science, University of California Los Angeles, 580 Portola Plaza, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California Los Angeles, 695 Charles E. Young Drive South, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.tibtech.2017.06.007DOI Listing
October 2017

Widespread Allelic Heterogeneity in Complex Traits.

Am J Hum Genet 2017 May;100(5):789-802

Department of Computer Science, University of California, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5420356PMC
May 2017

IPED2: Inheritance Path Based Pedigree Reconstruction Algorithm for Complicated Pedigrees.

IEEE/ACM Trans Comput Biol Bioinform 2017 Sep-Oct;14(5):1094-1103. Epub 2017 Mar 28.

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https://ieeexplore.ieee.org/document/7888513/
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http://dx.doi.org/10.1109/TCBB.2017.2688439DOI Listing
May 2018

Correcting for cell-type heterogeneity in DNA methylation: a comprehensive evaluation.

Nat Methods 2017 02;14(3):218-219

Department of Computer Science, University of California, Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1038/nmeth.4190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548185PMC
February 2017

Long Single-Molecule Reads Can Resolve the Complexity of the Influenza Virus Composed of Rare, Closely Related Mutant Variants.

J Comput Biol 2017 Jun 30;24(6):558-570. Epub 2016 Nov 30.

1 Department of Computer Science, Georgia State University , Atlanta, Georgia .

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http://dx.doi.org/10.1089/cmb.2016.0146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467126PMC
June 2017

Colocalization of GWAS and eQTL Signals Detects Target Genes.

Am J Hum Genet 2016 Dec 17;99(6):1245-1260. Epub 2016 Nov 17.

Department of Computer Science, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(16)30439-6.pdf
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http://biorxiv.org/content/biorxiv/early/2016/08/29/065037.f
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http://dx.doi.org/10.1016/j.ajhg.2016.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5142122PMC
December 2016

Chromosome conformation elucidates regulatory relationships in developing human brain.

Nature 2016 10 19;538(7626):523-527. Epub 2016 Oct 19.

Department of Neurology, Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1038/nature19847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358922PMC
October 2016

Efficient and Accurate Multiple-Phenotype Regression Method for High Dimensional Data Considering Population Structure.

Genetics 2016 Dec 21;204(4):1379-1390. Epub 2016 Oct 21.

Bioinformatics Interdepartmental Ph.D. Program, University of California, Los Angeles, California

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http://dx.doi.org/10.1534/genetics.116.189712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161272PMC
December 2016

The Genetic Basis of Host Preference and Resting Behavior in the Major African Malaria Vector, Anopheles arabiensis.

PLoS Genet 2016 09 15;12(9):e1006303. Epub 2016 Sep 15.

Vector Genetics Laboratory, Department of Pathology, Microbiology and Immunology/University of California, Davis, Davis, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025075PMC
September 2016

Using genomic annotations increases statistical power to detect eGenes.

Bioinformatics 2016 06;32(12):i156-i163

Department of Computer Science Department of Human Genetics, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908356PMC
June 2016

Imputing Phenotypes for Genome-wide Association Studies.

Am J Hum Genet 2016 Jul 9;99(1):89-103. Epub 2016 Jun 9.

Department of Computer Science, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297163013
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http://dx.doi.org/10.1016/j.ajhg.2016.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005435PMC
July 2016

Fast and Accurate Construction of Confidence Intervals for Heritability.

Am J Hum Genet 2016 06;98(6):1181-1192

Blavatnik School of Computer Science, Tel Aviv University, Tel Aviv 6997801, Israel; Molecular Microbiology and Biotechnology Department, Tel Aviv University, Tel Aviv 6997801, Israel; International Computer Science Institute, 1947 Center Street, Berkeley, CA 94704, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908190PMC
June 2016

ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis.

G3 (Bethesda) 2016 07 7;6(7):1793-8. Epub 2016 Jul 7.

Department of Computer Science, University of California, Los Angeles, California 90095 Department of Human Genetics, University of California, Los Angeles, California 90095

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http://dx.doi.org/10.1534/g3.116.029439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938634PMC
July 2016

Multiple testing correction in linear mixed models.

Genome Biol 2016 Apr 1;17:62. Epub 2016 Apr 1.

Computer Science Department, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1186/s13059-016-0903-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818520PMC
April 2016

Accounting for Population Structure in Gene-by-Environment Interactions in Genome-Wide Association Studies Using Mixed Models.

PLoS Genet 2016 Mar 4;12(3):e1005849. Epub 2016 Mar 4.

Computer Science Department, University of California, Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778803PMC
March 2016

A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping.

Hum Mol Genet 2016 05 21;25(9):1857-66. Epub 2016 Feb 21.

Division of Genetics, Division of Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA, Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA, Partners Center for Personalized Genetic Medicine, Boston, MA 02115, USA and Faculty of Medical and Human Sciences, University of Manchester, Manchester M13 9PL, UK.

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http://dx.doi.org/10.1093/hmg/ddw049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986332PMC
May 2016

Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains.

PLoS Genet 2015 Dec 22;11(12):e1005711. Epub 2015 Dec 22.

Departments of Medicine, Human Genetics, and Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4687930PMC
December 2015

The Genetic Architecture of Hearing Impairment in Mice: Evidence for Frequency-Specific Genetic Determinants.

G3 (Bethesda) 2015 Sep 4;5(11):2329-39. Epub 2015 Sep 4.

Department of Otolaryngology and Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033

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http://dx.doi.org/10.1534/g3.115.021592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632053PMC
September 2015

Genetic and environmental control of host-gut microbiota interactions.

Genome Res 2015 Oct 10;25(10):1558-69. Epub 2015 Aug 10.

Department of Medicine/Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA; Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1101/gr.194118.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579341PMC
October 2015

High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping.

G3 (Bethesda) 2015 Jul 28;5(10):2021-6. Epub 2015 Jul 28.

Departments of Human Genetics, Medicine, Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, California 90095-1679

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http://dx.doi.org/10.1534/g3.115.020784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592984PMC
July 2015

Identification of causal genes for complex traits.

Bioinformatics 2015 Jun;31(12):i206-13

Department of Computer Science, Inter-Departmental Program in Bioinformatics, Department of Human Genetics and Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095, USA Department of Computer Science, Inter-Departmental Program in Bioinformatics, Department of Human Genetics and Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btv240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542778PMC
June 2015

The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice.

Stem Cell Reports 2015 Jul 4;5(1):125-38. Epub 2015 Jun 4.

Department of Preventive Medicine and Institute for Genetic Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4618249PMC
July 2015

Accurate and fast multiple-testing correction in eQTL studies.

Am J Hum Genet 2015 Jun 28;96(6):857-68. Epub 2015 May 28.

Asan Institute for Life Sciences, Asan Medical Center, Seoul 138-736, Republic of Korea; Department of Medicine, University of Ulsan College of Medicine, Seoul 138-736, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457958PMC
June 2015

Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss.

PLoS Genet 2015 Apr 16;11(4):e1005094. Epub 2015 Apr 16.

Department of Otolaryngology, Zilkha Neurogenetic Institute, USC Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399881PMC
April 2015

Gene-Gene Interactions Detection Using a Two-stage Model.

J Comput Biol 2015 Jun 14;22(6):563-76. Epub 2015 Apr 14.

1Computer Science Department, University of California Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1089/cmb.2014.0163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449719PMC
June 2015

Efficient multiple-trait association and estimation of genetic correlation using the matrix-variate linear mixed model.

Genetics 2015 May 27;200(1):59-68. Epub 2015 Feb 27.

†Department of Computer Science, Department of Human Genetics, University of California, Los Angeles, California 90095

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http://dx.doi.org/10.1534/genetics.114.171447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4423381PMC
May 2015

Memory efficient assembly of human genome.

J Bioinform Comput Biol 2015 Apr 17;13(2):1550008. Epub 2014 Dec 17.

Department of Computer Science, University of California Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1142/S0219720015500080DOI Listing
April 2015

IPED2X: a robust pedigree reconstruction algorithm for complicated pedigrees.

J Bioinform Comput Biol 2014 Dec;12(6):1442007

IBM T.J. Watson Research, Yorktown Heights, USA.

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http://dx.doi.org/10.1142/S0219720014420074DOI Listing
December 2014

A spatial haplotype copying model with applications to genotype imputation.

J Comput Biol 2015 May 19;22(5):451-62. Epub 2014 Dec 19.

1 Department of Computer Science, University of California , Los Angeles, California.

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http://www.liebertpub.com/doi/10.1089/cmb.2014.0151
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http://dx.doi.org/10.1089/cmb.2014.0151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425418PMC
May 2015

Spatial localization of recent ancestors for admixed individuals.

G3 (Bethesda) 2014 Nov 3;4(12):2505-18. Epub 2014 Nov 3.

Interdepartmental Program in Bioinformatics, University of California, Los Angeles, California 90095 Department of Human Genetics, University of California, Los Angeles, California 90095 Department of Pathology and Laboratory Medicine, Geffen School of Medicine at University of California, Los Angeles, California 90095

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http://dx.doi.org/10.1534/g3.114.014274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267945PMC
November 2014

Integrating functional data to prioritize causal variants in statistical fine-mapping studies.

PLoS Genet 2014 Oct 30;10(10):e1004722. Epub 2014 Oct 30.

Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, California, United States of America; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America; Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214605PMC
October 2014

Identifying causal variants at loci with multiple signals of association.

Genetics 2014 Oct 7;198(2):497-508. Epub 2014 Aug 7.

Department of Computer Science, University of California, Los Angeles, California 90095 Department of Human Genetics, University of California, Los Angeles, California 90095

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http://dx.doi.org/10.1534/genetics.114.167908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196608PMC
October 2014

Accurate viral population assembly from ultra-deep sequencing data.

Bioinformatics 2014 Jun;30(12):i329-37

Computer Science Department, Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA, Department of Computer Science, Georgia State University, Atlanta, GA, 30303 and Department of Human Genetics, University of California, Los Angeles, CA 90095, USAComputer Science Department, Department of Molecular and Medical Pharmacology, University of California, Los Angeles, CA 90095, USA, Department of Computer Science, Georgia State University, Atlanta, GA, 30303 and Department of Human Genetics, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058922PMC
June 2014

Privacy preserving protocol for detecting genetic relatives using rare variants.

Bioinformatics 2014 Jun;30(12):i204-11

Department of Computer Science, Bioinformatics IDP, Department of Mathematics and Department of Human Genetics, University of California, LA 90095, USADepartment of Computer Science, Bioinformatics IDP, Department of Mathematics and Department of Human Genetics, University of California, LA 90095, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058916PMC
June 2014

Allele-specific expression and eQTL analysis in mouse adipose tissue.

BMC Genomics 2014 Jun 13;15:471. Epub 2014 Jun 13.

Department of Medicine/Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1186/1471-2164-15-471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4089026PMC
June 2014

Identifying genetic relatives without compromising privacy.

Genome Res 2014 Apr 10;24(4):664-72. Epub 2014 Mar 10.

Department of Computer Science, University of California, Los Angeles, Los Angeles, California 90095,USA;

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http://dx.doi.org/10.1101/gr.153346.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975065PMC
April 2014

Genome-wide association study for age-related hearing loss (AHL) in the mouse: a meta-analysis.

J Assoc Res Otolaryngol 2014 Jun 26;15(3):335-52. Epub 2014 Feb 26.

Department of Cell and Molecular Biology and Genetics, House Research Institute, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s10162-014-0443-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010595PMC
June 2014

Genetic implication of a novel thiamine transporter in human hypertension.

J Am Coll Cardiol 2014 Apr 5;63(15):1542-55. Epub 2014 Feb 5.

Department of Medicine, University of California at San Diego (UCSD), La Jolla, California; Veterans Affairs San Diego Healthcare System, San Diego, California; Department of Pharmacology and the Institute for Genomic Medicine, UCSD, La Jolla, California. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992204PMC
April 2014

Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice.

PLoS Genet 2014 Jan 9;10(1):e1004022. Epub 2014 Jan 9.

Department of Computer Science, University of California, Los Angeles, Los Angeles, California, United States of America ; Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3886926PMC
January 2014

Diversity, differentiation, and linkage disequilibrium: prospects for association mapping in the malaria vector Anopheles arabiensis.

G3 (Bethesda) 2014 Jan 10;4(1):121-31. Epub 2014 Jan 10.

Vector Genetics Laboratory, Department of Pathology, Microbiology, and Immunology, School of Veterinary Medicine, University of California-Davis, California 95616.

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http://dx.doi.org/10.1534/g3.113.008326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3887528PMC
January 2014

Fast pairwise IBD association testing in genome-wide association studies.

Bioinformatics 2014 Jan 24;30(2):206-13. Epub 2013 Oct 24.

Division of Genetics, Brigham and Women's Hospital and Division of Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA, Partners Center for Personalized Genetic Medicine, Boston, MA 02115, USA, Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA, Computer Science Department, University of California, Los Angeles, CA 90095, USA, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands, Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands and Department of Human Genetics, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892684PMC
January 2014

eALPS: estimating abundance levels in pooled sequencing using available genotyping data.

J Comput Biol 2013 Nov 21;20(11):861-77. Epub 2013 Oct 21.

1 The Blavatnik School of Computer Science, Tel-Aviv University , Tel Aviv, Israel .

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http://dx.doi.org/10.1089/cmb.2013.0105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013753PMC
November 2013

Efficiently identifying significant associations in genome-wide association studies.

J Comput Biol 2013 Oct 14;20(10):817-30. Epub 2013 Sep 14.

1 Computer Science Department, University of California , Los Angeles, California.

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http://dx.doi.org/10.1089/cmb.2013.0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791046PMC
October 2013

Leveraging reads that span multiple single nucleotide polymorphisms for haplotype inference from sequencing data.

Bioinformatics 2013 Sep 3;29(18):2245-52. Epub 2013 Jul 3.

Department of Computer Science and Inter-Departmental Program in Bioinformatics, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/bioinformatics/btt386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3753566PMC
September 2013

Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-analytic approaches.

PLoS Genet 2013 Jun 13;9(6):e1003491. Epub 2013 Jun 13.

Computer Science Department, University of California, Los Angeles, California, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3681686PMC
June 2013