Elana J Fertig

Elana J Fertig

UNVERIFIED PROFILE

Are you Elana J Fertig?   Register this Author

Register author
Elana J Fertig

Elana J Fertig

Publications by authors named "Elana J Fertig"

Are you Elana J Fertig?   Register this Author

52Publications

903Reads

-Profile Views

A Mechanism of Resistance to Antibody-Targeted Immune Attack.

Cancer Immunol Res 2019 Feb 18;7(2):230-243. Epub 2018 Dec 18.

Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/2326-6066.CIR-18-0266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6359950PMC
February 2019

Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-Regulated Genes.

Mol Cancer Res 2018 12 23;16(12):1889-1901. Epub 2018 Jul 23.

Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-18-0345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279594PMC
December 2018

Enter the Matrix: Factorization Uncovers Knowledge from Omics.

Trends Genet 2018 10 22;34(10):790-805. Epub 2018 Aug 22.

Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tig.2018.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309559PMC
October 2018

CancerInSilico: An R/Bioconductor package for combining mathematical and statistical modeling to simulate time course bulk and single cell gene expression data in cancer.

PLoS Comput Biol 2018 Jun 19;14(4):e1006935. Epub 2019 Apr 19.

Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1006935DOI Listing
June 2018

Digitizing omics profiles by divergence from a baseline.

Proc Natl Acad Sci U S A 2018 05 16;115(18):4545-4552. Epub 2018 Apr 16.

Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD 21218;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1721628115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939095PMC
May 2018

An unbiased in vivo functional genomics screening approach in mice identifies novel tumor cell-based regulators of immune rejection.

Cancer Immunol Immunother 2017 Dec 2;66(12):1529-1544. Epub 2017 Aug 2.

Department of Oncology and Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3970 Reservoir Road NW, Washington DC, 20057, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00262-017-2047-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5854209PMC
December 2017

StereoGene: rapid estimation of genome-wide correlation of continuous or interval feature data.

Bioinformatics 2017 Oct;33(20):3158-3165

Department of Bioengineering and Bioinformatics, Moscow State University, Moscow 119992, Russia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btx379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860031PMC
October 2017

A Software Application for Mining and Presenting Relevant Cancer Clinical Trials per Cancer Mutation.

Cancer Inform 2017 22;16:1176935117711940. Epub 2017 Jun 22.

Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1176935117711940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485907PMC
June 2017

Comparative mutational landscape analysis of patient-derived tumour xenografts.

Br J Cancer 2017 Feb 24;116(4):515-523. Epub 2017 Jan 24.

Department of Otolaryngology and Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/bjc.2016.450DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318980PMC
February 2017

Systems Approaches to Cancer Biology.

Cancer Res 2016 12 18;76(23):6774-6777. Epub 2016 Nov 18.

Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, District of Columbia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-16-1580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135591PMC
December 2016

Application of genomic and proteomic technologies in biomarker discovery.

Am Soc Clin Oncol Educ Book 2012 :377-82

From the Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD; Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14694/EdBook_AM.2012.32.377DOI Listing
April 2016

Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma.

Cancer Prev Res (Phila) 2016 04 9;9(4):265-74. Epub 2016 Feb 9.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. Ludwig Center for Cancer Genetics and Therapeutics, Howard Hughes Medical Institute, and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Surgery, Section of Otolaryngology-Head and Neck Surgery, The University of Chicago, Chicago, Illinois States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1940-6207.CAPR-15-0316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4818686PMC
April 2016

Toward Signaling-Driven Biomarkers Immune to Normal Tissue Contamination.

Cancer Inform 2016 10;15:15-21. Epub 2016 Feb 10.

Department of Mathematics and Statistics, The College of New Jersey, Ewing, NJ, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4137/CIN.S32468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4750896PMC
February 2016

Expression microarray analysis reveals alternative splicing of LAMA3 and DST genes in head and neck squamous cell carcinoma.

PLoS One 2014 27;9(3):e91263. Epub 2014 Mar 27.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America; Milton J. Dance Head and Neck Center, Greater Baltimore Medical Center, Baltimore, Maryland, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091263PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967989PMC
December 2015

Epigenetic screening of salivary gland mucoepidermoid carcinoma identifies hypomethylation of CLIC3 as a common alteration.

Oral Oncol 2015 Dec 17;51(12):1120-5. Epub 2015 Oct 17.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, USA; Milton J. Dance Jr. Head and Neck Center at the Greater Baltimore Medical Center, Baltimore, MD, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oraloncology.2015.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663116PMC
December 2015

Analysis of gene expression of secreted factors associated with breast cancer metastases in breast cancer subtypes.

Sci Rep 2015 Jul 15;5:12133. Epub 2015 Jul 15.

1] Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA [2] Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep12133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648401PMC
July 2015

switchBox: an R package for k-Top Scoring Pairs classifier development.

Bioinformatics 2015 Jan 26;31(2):273-4. Epub 2014 Sep 26.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, School of Medicine, Johns Hopkins University, Baltimore, MD 21205 and Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btu622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287945PMC
January 2015

p16 protein expression and human papillomavirus status as prognostic biomarkers of nonoropharyngeal head and neck squamous cell carcinoma.

J Clin Oncol 2014 Dec 29;32(35):3930-8. Epub 2014 Sep 29.

Christine H. Chung and Elana J. Fertig, Johns Hopkins University, Baltimore, MD; Qiang Zhang and Jonathan Harris, Radiation Therapy Oncology Group Statistical Center, Philadelphia, PA; Christina S. Kong and Quynh-Thu Le, Stanford University, Stanford; Richard C. Jordan, University of California at San Francisco, San Francisco, CA; Paul M. Harari, University of Wisconsin Carbone Cancer Center, Madison; Dian Wang, Medical College of Wisconsin, Milwaukee, WI; Kevin P. Redmond, University of Cincinnati, Cincinnati; Maura L. Gillison, Ohio State University, Columbus, OH; George Shenouda, McGill University Health Centre, Montreal, Quebec, Canada; Andy Trotti, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; and David Raben, University of Colorado, Denver, CO.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2013.54.5228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251957PMC
December 2014

Learning dysregulated pathways in cancers from differential variability analysis.

Cancer Inform 2014 23;13(Suppl 5):61-7. Epub 2014 Oct 23.

Assistant Professor, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4137/CIN.S14066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4218688PMC
November 2014

Preserving biological heterogeneity with a permuted surrogate variable analysis for genomics batch correction.

Bioinformatics 2014 Oct 6;30(19):2757-63. Epub 2014 Jun 6.

Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21205, USA, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119333, Russia, Research Institute for Genetics and Selection of Industrial Microorganisms "GosNIIGenetika", Moscow 117545, Russia, Department of Statistics and Biostatistics, Rutgers University, NJ 08854, USA and Division of Allergy & Clinical Immunology, Department of Medicine, Johns Hopkins University, Baltimore, MD 21224, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btu375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173013PMC
October 2014

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC.

Oncotarget 2014 Oct;5(19):9281-94

Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. The Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253434PMC
http://dx.doi.org/10.18632/oncotarget.2423DOI Listing
October 2014

Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis.

Nat Commun 2014 Sep 2;5:4715. Epub 2014 Sep 2.

1] Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA [2] Department of Chemical and Biomolecular Engineering, School of Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA [3] Department of Oncology, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms5715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351998PMC
September 2014

Pattern identification in time-course gene expression data with the CoGAPS matrix factorization.

Methods Mol Biol 2014 ;1101:87-112

Oncology Biostatistics and Bioinformatics, Johns Hopkins University, Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-62703-721-1_6DOI Listing
June 2014

Identifying context-specific transcription factor targets from prior knowledge and gene expression data.

IEEE Trans Nanobioscience 2013 Sep 16;12(3):142-9. Epub 2013 May 16.

Department of Oncology, SKCCC, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/TNB.2013.2263390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3759534PMC
September 2013

Dynamics in hybrid complex systems of switches and oscillators.

Chaos 2013 Sep;23(3):033142

Department of Applied Mathematics, University of Colorado, Boulder, Colorado 80309, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1063/1.4822017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795755PMC
September 2013

Inhibition of TGF-β enhances the in vivo antitumor efficacy of EGF receptor-targeted therapy.

Mol Cancer Ther 2012 Nov 27;11(11):2429-39. Epub 2012 Aug 27.

Head and Neck Cancer Research Division, Department of Otolaryngology-Head and Neck Surgery, 1550 Orleans Street, Johns Hopkins University School of Medicine, Cancer Research Building II, Baltimore, MD 21231, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-12-0101-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640459PMC
November 2012

Hybrid Modeling of Cell Signaling and Transcriptional Reprogramming and Its Application in C. elegans Development.

Front Genet 2011 8;2:77. Epub 2011 Nov 8.

Division of Oncology Biostatistics and Bioinformatics, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University Baltimore, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2011.00077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268630PMC
October 2012

Quantifying the dynamics of coupled networks of switches and oscillators.

PLoS One 2012 5;7(1):e29497. Epub 2012 Jan 5.

Physics Department, Randolph-Macon College, Ashland, Virginia, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029497PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252330PMC
May 2012

Matrix Factorization for Transcriptional Regulatory Network Inference.

IEEE Symp Comput Intell Bioinforma Comput Biol Proc 2012 May;2012:387-396

School of Medicine, Johns Hopkins University, Baltimore, MD 21205.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1109/CIBCB.2012.6217256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212829PMC
May 2012

CoGAPS: an R/C++ package to identify patterns and biological process activity in transcriptomic data.

Bioinformatics 2010 Nov 1;26(21):2792-3. Epub 2010 Sep 1.

Department of Oncology and Division of Oncology, Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btq503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025742PMC
November 2010