Elaine T Lim

Elaine T Lim

UNVERIFIED PROFILE

Are you Elaine T Lim?   Register this Author

Register author
Elaine T Lim

Elaine T Lim

Publications by authors named "Elaine T Lim"

Are you Elaine T Lim?   Register this Author

22Publications

846Reads

21Profile Views

Enabling multiplexed testing of pooled donor cells through whole-genome sequencing.

Genome Med 2018 04 19;10(1):31. Epub 2018 Apr 19.

Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
https://genomemedicine.biomedcentral.com/articles/10.1186/s1
Publisher Site
http://dx.doi.org/10.1186/s13073-018-0541-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909281PMC
April 2018

Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development.

Am J Hum Genet 2015 May 9;96(5):695-708. Epub 2015 Apr 9.

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajhg.2015.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570286PMC
May 2015

No evidence for rare recessive and compound heterozygous disruptive variants in schizophrenia.

Eur J Hum Genet 2015 Apr 5;23(4):555-7. Epub 2014 Nov 5.

1] Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA [2] Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA [3] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA [4] Analytic and Translational Genetics Unit, Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2014.228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666583PMC
April 2015

A novel test for recessive contributions to complex diseases implicates Bardet-Biedl syndrome gene BBS10 in idiopathic type 2 diabetes and obesity.

Am J Hum Genet 2014 Nov 16;95(5):509-20. Epub 2014 Oct 16.

Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029297140039
Publisher Site
http://dx.doi.org/10.1016/j.ajhg.2014.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225638PMC
November 2014

Distribution and medical impact of loss-of-function variants in the Finnish founder population.

PLoS Genet 2014 Jul 31;10(7):e1004494. Epub 2014 Jul 31.

Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Psychiatric & Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1004494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117444PMC
July 2014

An excess of risk-increasing low-frequency variants can be a signal of polygenic inheritance in complex diseases.

Am J Hum Genet 2014 Mar;94(3):437-52

Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA; Department of Endocrinology, Boston Children's Hospital, Boston, MA 02115, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00029297140006
Publisher Site
http://dx.doi.org/10.1016/j.ajhg.2014.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951950PMC
March 2014