Elaine R Peskind

Elaine R Peskind

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Elaine R Peskind

Elaine R Peskind

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Variables associated with subjective cognitive change among Iraq and Afghanistan war Veterans with blast-related mild traumatic brain injury.

J Clin Exp Neuropsychol 2019 Sep 20;41(7):680-693. Epub 2019 May 20.

b Veterans Affairs Northwest Network Mental Illness , Research, Education, and Clinical Center, Veterans Affairs Puget Sound Healthcare System , Seattle , WA , USA.

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http://dx.doi.org/10.1080/13803395.2019.1611740DOI Listing
September 2019

Fine Particulate Matter Exposure and Cerebrospinal Fluid Markers of Vascular Injury.

J Alzheimers Dis 2019 ;71(3):1015-1025

VA Northwest Network Mental Illness Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, USA.

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http://dx.doi.org/10.3233/JAD-190563DOI Listing
January 2019

Blast exposure elicits blood-brain barrier disruption and repair mediated by tight junction integrity and nitric oxide dependent processes.

Sci Rep 2018 07 27;8(1):11344. Epub 2018 Jul 27.

Geriatric Research Education and Clinical Center (GRECC), Veterans Affairs Puget Sound Health Care System, Seattle, WA, 98108, USA.

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http://dx.doi.org/10.1038/s41598-018-29341-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063850PMC
July 2018

Biofluid biomarkers of traumatic brain injury.

Brain Inj 2017 ;31(9):1195-1203

c VA Northwest Network Mental Illness Research, Education, and Clinical Center , Veterans Affairs Puget Sound Health Care System , Seattle , WA , USA.

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http://dx.doi.org/10.1080/02699052.2017.1357836DOI Listing
June 2018

Associations between CSF cortisol and CSF norepinephrine in cognitively normal controls and patients with amnestic MCI and AD dementia.

Int J Geriatr Psychiatry 2018 05 15;33(5):763-768. Epub 2018 Feb 15.

Mental Illness Research, Education, and Clinical Center (MIRECC), VA Puget Sound Health Care System, Seattle, WA, USA.

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http://dx.doi.org/10.1002/gps.4856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882504PMC
May 2018

Retrospective and Prospective Memory Among OEF/OIF/OND Veterans With a Self-Reported History of Blast-Related mTBI.

J Int Neuropsychol Soc 2018 04 29;24(4):324-334. Epub 2017 Dec 29.

1Veterans Affairs (VA) Northwest Network (VISN 20) Mental Illness,Research,Education,and Clinical Center (MIRECC),Veterans Affairs Puget Sound Health Care System,Seattle,Washington.

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http://dx.doi.org/10.1017/S1355617717001217DOI Listing
April 2018

Prazosin for Post-Traumatic Stress Disorder.

N Engl J Med 2018 04;378(17):1649-1650

VA Northwest Network Mental Illness Research, Education, and Clinical Center, Seattle, WA

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http://dx.doi.org/10.1056/NEJMc1803171DOI Listing
April 2018

Effect of dietary palmitic and stearic acids on sucrose motivation and hypothalamic and striatal cell signals in the rat.

Am J Physiol Regul Integr Comp Physiol 2018 02 1;314(2):R191-R200. Epub 2017 Nov 1.

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine , Seattle, Washington.

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http://dx.doi.org/10.1152/ajpregu.00340.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867676PMC
February 2018

Trial of Prazosin for Post-Traumatic Stress Disorder in Military Veterans.

N Engl J Med 2018 02;378(6):507-517

From the Veterans Affairs (VA) Northwest Network Mental Illness Research, Education, and Clinical Center (M.A.R., E.R.P., H.A.H., K.L.H., M.M.) and the Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine (M.A.R., E.R.P., M.M.), Seattle; VA Cooperative Studies Program Coordinating Center, Palo Alto (B.C., M.-C.S., Y.L.), VA Long Beach Healthcare System, Department of Human Behavior, University of California, Irvine (C.R.), the Department of Health Research and Policy, Stanford University School of Medicine, Stanford (M.-C.S., Y.L.), and the VA San Diego Healthcare System (M.B.S.) and the Departments of Psychiatry and Family Medicine and Public Health, University of California at San Diego (M.B.S.), San Diego - all in California; VA Cooperative Studies Program Clinical Research Pharmacy Coordinating Center, Albuquerque, NM (C.H., A.D.-K.); the Department of Psychiatry, Howard University (T.A.M.), and the Cooperative Studies Program Central Office (G.D.H.), Department of Veterans Affairs, Office of Research and Development (T.G.), Washington, DC; VA Salt Lake City, Salt Lake City (J.R.); VA Northeast Program Evaluation Center, West Haven, and the Departments of Psychiatry and Public Health, Yale School of Medicine, New Haven - both in Connecticut (R.R.); and Providence VA Medical Center and the Department of Psychiatry and Human Behavior, Brown Alpert Medical School, Providence, RI (R.S.).

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http://dx.doi.org/10.1056/NEJMoa1507598DOI Listing
February 2018

Evidence for altered brain reactivity to norepinephrine in Veterans with a history of traumatic stress.

Neurobiol Stress 2018 Feb 15;8:103-111. Epub 2018 Mar 15.

VISN 20 Northwest Network Mental Illness Research, Education, and Clinical Center (MIRECC), VA Puget Sound Health Care System, 1660 S. Columbian Way, S116 MIRECC, Seattle, WA 98108, USA.

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http://dx.doi.org/10.1016/j.ynstr.2018.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991318PMC
February 2018

Effect of simvastatin on CSF Alzheimer disease biomarkers in cognitively normal adults.

Neurology 2017 Sep 18;89(12):1251-1255. Epub 2017 Aug 18.

From the Geriatric Research, Education, and Clinical Center (G.L., W.H.R.) and Northwest Network (VISN-20) Mental Illness, Research, Education, and Clinical Center (G.L., C.L.M., D.M., S.P.M., E.C.P., M.A.R., E.R.P.), Veterans Affairs Puget Sound Health Care System; Departments of Psychiatry and Behavioral Sciences (G.L., E.C.P., M.C., M.A.R., E.R.P.) and Medicine (W.H.R.), University of Washington, Seattle; and Department of Neurology (A.M.F.), Washington University in St. Louis, MO.

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http://dx.doi.org/10.1212/WNL.0000000000004392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606918PMC
September 2017

Mass-Spectrometry-Based Method To Quantify in Parallel Tau and Amyloid β 1-42 in CSF for the Diagnosis of Alzheimer's Disease.

J Proteome Res 2017 03 7;16(3):1228-1238. Epub 2017 Feb 7.

Department of Pathology, School of Medicine, University of Washington , Seattle, Washington 98104, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679294PMC
March 2017

CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease.

Alzheimers Dement 2016 11 24;12(11):1125-1131. Epub 2016 May 24.

Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA; Department of Pathology, Peking University Health Science Center and Peking University Third Hospital, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2016.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5107127PMC
November 2016

Higher Pretreatment Blood Pressure Is Associated With Greater Posttraumatic Stress Disorder Symptom Reduction in Soldiers Treated With Prazosin.

Biol Psychiatry 2016 11 11;80(10):736-742. Epub 2016 Apr 11.

Northwest Network Veterans Integrated Service Network 20 Mental Illness Research, Education and Clinical Center; Seattle; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle.

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http://dx.doi.org/10.1016/j.biopsych.2016.03.2108DOI Listing
November 2016

Increased CSF E-Selectin in Clinical Alzheimer's Disease without Altered CSF Aβ42 and Tau.

J Alzheimers Dis 2015 ;47(4):883-7

Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.3233/JAD-150420DOI Listing
July 2016

Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction.

Sci Transl Med 2016 Jan;8(321):321ra6

Geriatric Research Education and Clinical Center, VA Puget Sound Health Care System, Seattle, WA 98108, USA. Department of Medicine, University of Washington, Seattle, WA 98195, USA. Department of Pharmacology, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa9585DOI Listing
January 2016

Biofluid Biomarkers of Mild Traumatic Brain Injury: Whither Plasma Tau.

JAMA Neurol 2015 Oct;72(10):1103-5

Department of Pathology, University of Washington School of Medicine, Seattle.

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http://dx.doi.org/10.1001/jamaneurol.2015.1789DOI Listing
October 2015

Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease.

J Neuropathol Exp Neurol 2015 Jul;74(7):672-87

From the Department of Pathology, University of Washington, Seattle, WA (YY, CDK, EC, AMW, KSM, JZ, GSB, TJM); Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA; (ERP, GL); VA Northwest Network Mental Illness Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, WA (ERP); Department of Neurosciences, University of California San Diego, La Jolla, CA (DRG); Department of Neurology, University of Washington, Seattle, WA (S-CH); Department of Medicine, University of Washington, Seattle, WA (C-EY); Geriatric Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, WA (C-EY); Department of Laboratory Medicine, University of Washington, Seattle, WA (GSB); and Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA (BTH).

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http://dx.doi.org/10.1097/NEN.0000000000000207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471879PMC
July 2015

Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

Mov Disord 2015 Jun 24;30(7):936-44. Epub 2015 Mar 24.

Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1002/mds.26172DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478197PMC
June 2015

A Luminex assay detects amyloid β oligomers in Alzheimer's disease cerebrospinal fluid.

PLoS One 2013 2;8(7):e67898. Epub 2013 Jul 2.

Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067898PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699502PMC
February 2014

Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects.

Neurobiol Aging 2014 Feb 4;35(2):357-64. Epub 2013 Sep 4.

Northwest Network VISN-20 Mental Illness Research, Education, and Clinical Center, VA Puget Sound Health Care System, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.07.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859300PMC
February 2014

Pulse pressure is associated with Alzheimer biomarkers in cognitively normal older adults.

Neurology 2013 Dec 13;81(23):2024-7. Epub 2013 Nov 13.

From the Veterans Affairs San Diego Healthcare System (D.A.N., M.W.B., L.D.-W.), San Diego; Departments of Neurosciences (S.D.E., D.P.S., D.R.G.) and Psychiatry (M.W.B., L.D.-W.), University of California, San Diego, La Jolla, CA; VA Puget Sound Health Care System (E.R.P.), Mental Illness Research, Education, and Clinical Center, Seattle; Departments of Psychiatry and Behavioral Sciences (E.R.P.), University of Washington School of Medicine, Seattle, WA; Department of Neurology (J.F.Q.), Oregon Health and Science University, Portland; and Portland VA Medical Center (J.F.Q.), Portland, OR.

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http://www.neurology.org/cgi/doi/10.1212/01.wnl.0000436935.4
Publisher Site
http://dx.doi.org/10.1212/01.wnl.0000436935.47657.78DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854831PMC
December 2013

Cerebrospinal fluid norepinephrine and cognition in subjects across the adult age span.

Neurobiol Aging 2013 Oct 30;34(10):2287-92. Epub 2013 Apr 30.

Mental Illness Research and Education Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2013.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706572PMC
October 2013

TOMM40 intron 6 poly-T length, age at onset, and neuropathology of AD in individuals with APOE ε3/ε3.

Alzheimers Dement 2013 Sep 22;9(5):554-61. Epub 2012 Nov 22.

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.jalz.2012.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606272PMC
September 2013

MicroRNA in Alzheimer's disease: an exploratory study in brain, cerebrospinal fluid and plasma.

Biomarkers 2013 Aug 3;18(5):455-66. Epub 2013 Jul 3.

Department of Geriatric (GRECC), Research, Education, and Clinical Centers, VA Puget Sound Health Care System, Seattle, WA 98108, USA.

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http://dx.doi.org/10.3109/1354750X.2013.814073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3967870PMC
August 2013

Military- and sports-related mild traumatic brain injury: clinical presentation, management, and long-term consequences.

J Clin Psychiatry 2013 Feb;74(2):180-8; quiz 188

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.

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http://dx.doi.org/10.4088/JCP.12011co1cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904388PMC
February 2013

Tau phosphorylation pathway genes and cerebrospinal fluid tau levels in Alzheimer's disease.

Am J Med Genet B Neuropsychiatr Genet 2012 Oct 27;159B(7):874-83. Epub 2012 Aug 27.

Geriatric Research, Education, and Clinical Center (GRECC), VA Puget Sound Health Care System, Seattle, Washington 98108, USA.

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http://dx.doi.org/10.1002/ajmg.b.32094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3626266PMC
October 2012

ADAM10 expression and promoter haplotype in Alzheimer's disease.

Neurobiol Aging 2012 Sep 8;33(9):2229.e1-2229.e9. Epub 2012 May 8.

Geriatric Research, Education, and Clinical Center (GRECC), VA Puget Sound Health Care System, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2012.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391324PMC
September 2012

Age-dependent changes in the cerebrospinal fluid proteome by slow off-rate modified aptamer array.

Am J Pathol 2012 Feb 26;180(2):446-56. Epub 2011 Nov 26.

Department of Laboratory Medicine, University of Washington, Harborview Medical Center, Box 359743, 325 9th Avenue, Seattle, WA 98105, USA.

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http://dx.doi.org/10.1016/j.ajpath.2011.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349859PMC
February 2012

Modeling of pathological traits in Alzheimer's disease based on systemic extracellular signaling proteome.

Mol Cell Proteomics 2011 Oct 8;10(10):M111.008862. Epub 2011 Jul 8.

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305-5235, USA.

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http://dx.doi.org/10.1074/mcp.M111.008862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205866PMC
October 2011

The role of norepinephrine in differential response to stress in an animal model of posttraumatic stress disorder.

Biol Psychiatry 2011 Sep 20;70(5):441-8. Epub 2011 Jan 20.

Mental Illness Research, Education, and Clinical Center, Department of Veterans Affairs Puget Sound Health Care System, University of Washington School of Medicine, Seattle, Washington; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.

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http://dx.doi.org/10.1016/j.biopsych.2010.11.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740168PMC
September 2011

Cerebrocerebellar hypometabolism associated with repetitive blast exposure mild traumatic brain injury in 12 Iraq war Veterans with persistent post-concussive symptoms.

Neuroimage 2011 Jan 10;54 Suppl 1:S76-82. Epub 2010 Apr 10.

Northwest Network Mental Illness, Research, Education, and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.

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http://dx.doi.org/10.1016/j.neuroimage.2010.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264671PMC
January 2011

Prazosin treatment of trauma nightmares and sleep disturbance in soldiers deployed in Iraq.

J Trauma Stress 2010 Oct;23(5):645-8

Madigan Army Medical Center and VA Northwest Network Mental Illness, VA Puget Sound Health Care System, 1660 S. Columbian Way, Seattle, WA 98108, USA.

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http://dx.doi.org/10.1002/jts.20570DOI Listing
October 2010

Age-varying association between statin use and incident Alzheimer's disease.

J Am Geriatr Soc 2010 Jul 1;58(7):1311-7. Epub 2010 Jun 1.

Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2010.02906.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3176730PMC
July 2010

Adrenocortical responsiveness to infusions of physiological doses of ACTH is not altered in posttraumatic stress disorder.

Front Behav Neurosci 2009 30;3:40. Epub 2009 Oct 30.

Northwest Network VISN 20 Mental Illness Research, Education and Clinical Center, VA Puget Sound Health Care System Seattle, WA, USA.

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http://journal.frontiersin.org/article/10.3389/neuro.08.040.
Publisher Site
http://dx.doi.org/10.3389/neuro.08.040.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773172PMC
December 2009

Prazosin for the treatment of behavioral symptoms in patients with Alzheimer disease with agitation and aggression.

Am J Geriatr Psychiatry 2009 Sep;17(9):744-51

VA Northwest Network Mental Illness Research, Education, and Clinical Center (MIRECC), Seattle, WA 98115, USA.

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http://dx.doi.org/10.1097/JGP.0b013e3181ab8c61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2842091PMC
September 2009

Apolipoprotein E highly correlates with AbetaPP- and tau-related markers in human cerebrospinal fluid.

J Alzheimers Dis 2008 Nov;15(3):409-17

Northwest Lipid Metabolism and Diabetes Research Laboratories, University of Washington School of Medicine, Seattle, WA 98109, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667787PMC
http://dx.doi.org/10.3233/jad-2008-15307DOI Listing
November 2008

Cerebrospinal fluid: when is it worthwhile to do a lumbar puncture?

Authors:
Elaine R Peskind

CNS Spectr 2008 Oct;13(10 Suppl 16):25-7

Alzheimer's Disease Research Center, Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington, USA.

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http://dx.doi.org/10.1017/s1092852900027012DOI Listing
October 2008

Altered medial temporal lobe responses during visuospatial encoding in healthy APOE*4 carriers.

Neurobiol Aging 2008 Jul 9;29(7):981-91. Epub 2007 Mar 9.

Mental Illness Research, Education, and Clinical Center (MIRECC), Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943631PMC
July 2008

Prazosin effects on objective sleep measures and clinical symptoms in civilian trauma posttraumatic stress disorder: a placebo-controlled study.

Biol Psychiatry 2008 Mar 14;63(6):629-32. Epub 2007 Sep 14.

Northwest Network VISN 20 Mental Illness Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington 98108, USA.

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http://dx.doi.org/10.1016/j.biopsych.2007.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2350188PMC
March 2008

Biomarkers for Alzheimer's disease.

Expert Rev Neurother 2007 Aug;7(8):1021-8

Department of Pathology, University of Washington, Seattle, WA 98104-2499, USA.

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http://dx.doi.org/10.1586/14737175.7.8.1021DOI Listing
August 2007

A parallel group placebo controlled study of prazosin for trauma nightmares and sleep disturbance in combat veterans with post-traumatic stress disorder.

Biol Psychiatry 2007 Apr 25;61(8):928-34. Epub 2006 Oct 25.

Veterans Affairs Northwest Network Mental Illness Research, Education and Clinical Center (MIRECC), University of Washington, Seattle, Washington, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000632230600862
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http://dx.doi.org/10.1016/j.biopsych.2006.06.032DOI Listing
April 2007

Statins of different brain penetrability differentially affect CSF PLTP activity.

Dement Geriatr Cogn Disord 2006 7;22(5-6):392-8. Epub 2006 Sep 7.

Department of Medicine, University of Washington School of Medicine, Seattle, WA, USA.

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https://www.karger.com/Article/FullText/95679
Publisher Site
http://dx.doi.org/10.1159/000095679DOI Listing
February 2007

Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid.

J Alzheimers Dis 2006 Dec;10(4):399-406

Department of Medicine, Division of Geriatric Medicine, University of Washington School of Medicine, and VA Puget Sound Health Care System, Seattle, WA 98108, USA.

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http://dx.doi.org/10.3233/jad-2006-10408DOI Listing
December 2006

Memantine treatment in mild to moderate Alzheimer disease: a 24-week randomized, controlled trial.

Am J Geriatr Psychiatry 2006 Aug;14(8):704-15

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine and Veterans Affairs Northwest Network Mental Illness Research, Education, and Clinical Center, Seattle, WA 98108, USA.

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http://dx.doi.org/10.1097/01.JGP.0000224350.82719.83DOI Listing
August 2006