Elaine R Mardis

Elaine R Mardis

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Elaine R Mardis

Elaine R Mardis

Publications by authors named "Elaine R Mardis"

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Immunotherapeutic Challenges for Pediatric Cancers.

Mol Ther Oncolytics 2019 Dec 28;15:38-48. Epub 2019 Aug 28.

The Research Institute at Nationwide Children's Hospital, Center for Childhood Cancer and Blood Diseases, The Ohio State University College of Medicine, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.omto.2019.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804520PMC
December 2019

Next-Generation Sequencing Technologies.

Cold Spring Harb Perspect Med 2019 Nov 1;9(11). Epub 2019 Nov 1.

Institute for Genomic Medicine at Nationwide Children's Hospital, The Ohio State University College of Medicine, The Institute for Genomic Medicine, Columbus, Ohio 43205.

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http://dx.doi.org/10.1101/cshperspect.a036798DOI Listing
November 2019

Pediatric cancer: case studies illustrate mechanisms to address significant challenges.

Cold Spring Harb Mol Case Stud 2019 Oct 23;5(5). Epub 2019 Oct 23.

Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, Ohio 43215, USA.

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http://dx.doi.org/10.1101/mcs.a004788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824256PMC
October 2019

The Impact of Next-Generation Sequencing on Cancer Genomics: From Discovery to Clinic.

Authors:
Elaine R Mardis

Cold Spring Harb Perspect Med 2019 Sep 3;9(9). Epub 2019 Sep 3.

The Ohio State University College of Medicine, Columbus, Ohio 43205.

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http://perspectivesinmedicine.cshlp.org/lookup/doi/10.1101/c
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http://dx.doi.org/10.1101/cshperspect.a036269DOI Listing
September 2019

miRNAs and Long-term Breast Cancer Survival: Evidence from the WHEL Study.

Cancer Epidemiol Biomarkers Prev 2019 Sep 11;28(9):1525-1533. Epub 2019 Jun 11.

Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-1322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726562PMC
September 2019

Research-based PAM50 signature and long-term breast cancer survival.

Breast Cancer Res Treat 2019 Sep 21. Epub 2019 Sep 21.

Department of Family Medicine and Public Health, University of California, San Diego, 3855 Health Sciences Drive #0901, La Jolla, CA, 92093-0901, USA.

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http://dx.doi.org/10.1007/s10549-019-05446-yDOI Listing
September 2019

Expanding the clinical history associated with syndromic Klippel-Feil: A unique case of comorbidity with medulloblastoma.

Eur J Med Genet 2019 Aug 10;62(8):103701. Epub 2019 Jun 10.

Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA; Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.ejmg.2019.103701DOI Listing
August 2019

Samovar: Single-Sample Mosaic Single-Nucleotide Variant Calling with Linked Reads.

iScience 2019 Aug 29;18:1-10. Epub 2019 May 29.

Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA; Department of Biology, Johns Hopkins University, Baltimore, MD, USA; Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2019.05.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609817PMC
August 2019

Precision oncogenomics.

Cold Spring Harb Mol Case Stud 2019 Apr 1;5(2). Epub 2019 Apr 1.

Nationwide Children's Hospital and the Ohio State University, Columbus, Ohio 43215, USA.

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http://dx.doi.org/10.1101/mcs.a004150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549571PMC
April 2019

Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.

Cancer Cell 2018 09 23;34(3):411-426.e19. Epub 2018 Aug 23.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, MS 323, Memphis, TN 38105-3678, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, TN 38105, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158019PMC
September 2018

Oral Cavity Squamous Cell Carcinoma Xenografts Retain Complex Genotypes and Intertumor Molecular Heterogeneity.

Cell Rep 2018 08;24(8):2167-2178

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63108, USA; Department of Medicine, Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO 63108, USA; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63108, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183116
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http://dx.doi.org/10.1016/j.celrep.2018.07.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6417872PMC
August 2018

The emerging clinical relevance of genomics in cancer medicine.

Nat Rev Clin Oncol 2018 06;15(6):353-365

Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA.

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http://dx.doi.org/10.1038/s41571-018-0002-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6658089PMC
June 2018

Clinical and Genomic Insights from Metastatic Cancers.

Authors:
Elaine R Mardis

Clin Chem 2018 05 4;64(5):766-768. Epub 2018 Jan 4.

Nationwide Children's Hospital and Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH.

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http://dx.doi.org/10.1373/clinchem.2017.281501DOI Listing
May 2018

Resistance-promoting effects of ependymoma treatment revealed through genomic analysis of multiple recurrences in a single patient.

Cold Spring Harb Mol Case Stud 2018 04 2;4(2). Epub 2018 Apr 2.

Institute for Genomic Medicine, Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, Ohio 43205, USA.

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http://molecularcasestudies.cshlp.org/lookup/doi/10.1101/mcs
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http://dx.doi.org/10.1101/mcs.a002444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880262PMC
April 2018

The era of precision oncogenomics.

Cold Spring Harb Mol Case Stud 2018 04 2;4(2). Epub 2018 Apr 2.

Institute for Genomic Medicine at Nationwide Children's Hospital and Department of Pediatrics, The Ohio State University, Columbus, Ohio 43215, USA.

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http://dx.doi.org/10.1101/mcs.a002915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880272PMC
April 2018

New additions to the cancer precision medicine toolkit.

Authors:
Elaine R Mardis

Genome Med 2018 04 13;10(1):28. Epub 2018 Apr 13.

Institute for Genomic Medicine at Nationwide Children's Hospital, 575 Children's Crossroad, Columbus, OH, 43205, USA.

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http://dx.doi.org/10.1186/s13073-018-0540-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899382PMC
April 2018

Cancer Immunogenomics: Computational Neoantigen Identification and Vaccine Design.

Cold Spring Harb Symp Quant Biol 2016 7;81:105-111. Epub 2017 Apr 7.

Nationwide Children's Hospital, Institute for Genomic Medicine, Columbus, Ohio 43205.

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http://dx.doi.org/10.1101/sqb.2016.81.030726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5702270PMC
February 2018

TP53 Germline Variations Influence the Predisposition and Prognosis of B-Cell Acute Lymphoblastic Leukemia in Children.

J Clin Oncol 2018 02 4;36(6):591-599. Epub 2018 Jan 4.

Maoxiang Qian, Xueyuan Cao, Wenjian Yang, Cheng Cheng, Hui Zhang, Takaya Moriyama, Gerard Zambetti, Kim E. Nichols, Ching-Hon Pui, Charles G. Mullighan, William E. Evans, Mary V. Relling, and Jun J. Yang, St Jude Children's Research Hospital, Memphis, TN; Meenakshi Devidas and Yunfeng Dai, University of Florida, Gainesville, FL; Andrew Carroll, University of Alabama at Birmingham, Birmingham, AL; Nyla A. Heerema and Julie M. Gastier-Foster, The Ohio State University and Wexner Medical Center; Julie M. Gastier-Foster and Elaine R. Mardis, Nationwide Children's Hospital, Columbus, OH; Hui Zhang, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong; Heng Xu, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China; Elizabeth Raetz, University of Utah, Salt Lake City, UT; Eric Larsen, Maine Children's Cancer Program, Scarborough, ME; Naomi Winick, University of Texas Southwestern Medical Center, Dallas; W. Paul Bowman, Cook Children's Medical Center, Fort Worth, TX; Paul L. Martin, Duke University, Durham, NC; Robert Fulton, Washington University School of Medicine, St Louis, MO; Michael Borowitz, Johns Hopkins Medical Institute, Baltimore, MD; Brent Wood, University of Washington, Seattle, WA; William L. Carroll, New York University, New York, NY; Stephen P. Hunger, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA; and Mignon L. Loh, Benioff Children's Hospital and University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1200/JCO.2017.75.5215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815403PMC
February 2018

Comprehensive discovery of noncoding RNAs in acute myeloid leukemia cell transcriptomes.

Exp Hematol 2017 11 28;55:19-33. Epub 2017 Jul 28.

The McDonnell Genome Institute, Washington University, St. Louis, MO; Department of Medicine, Washington University, St. Louis, MO; Siteman Cancer Center, Washington University, St. Louis, MO; Department of Biomedical Engineering, Washington University, St. Louis, MO. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772960PMC
November 2017

Melorheostosis: Exome sequencing of an associated dermatosis implicates postzygotic mosaicism of mutated KRAS.

Bone 2017 Aug 21;101:145-155. Epub 2017 Apr 21.

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Genomics and Bioinformatics, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2017.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518630PMC
August 2017

Retrotransposons Are the Major Contributors to the Expansion of the Muller F Element.

Authors:
Wilson Leung Christopher D Shaffer Elizabeth J Chen Thomas J Quisenberry Kevin Ko John M Braverman Thomas C Giarla Nathan T Mortimer Laura K Reed Sheryl T Smith Srebrenka Robic Shannon R McCartha Danielle R Perry Lindsay M Prescod Zenyth A Sheppard Ken J Saville Allison McClish Emily A Morlock Victoria R Sochor Brittney Stanton Isaac C Veysey-White Dennis Revie Luis A Jimenez Jennifer J Palomino Melissa D Patao Shane M Patao Edward T Himelblau Jaclyn D Campbell Alexandra L Hertz Maddison F McEvilly Allison R Wagner James Youngblom Baljit Bedi Jeffery Bettincourt Erin Duso Maiye Her William Hilton Samantha House Masud Karimi Kevin Kumimoto Rebekah Lee Darryl Lopez George Odisho Ricky Prasad Holly Lyn Robbins Tanveer Sandhu Tracy Selfridge Kara Tsukashima Hani Yosif Nighat P Kokan Latia Britt Alycia Zoellner Eric P Spana Ben T Chlebina Insun Chong Harrison Friedman Danny A Mammo Chun L Ng Vinayak S Nikam Nicholas U Schwartz Thomas Q Xu Martin G Burg Spencer M Batten Lindsay M Corbeill Erica Enoch Jesse J Ensign Mary E Franks Breanna Haiker Judith A Ingles Lyndsay D Kirkland Joshua M Lorenz-Guertin Jordan Matthews Cody M Mittig Nicholaus Monsma Katherine J Olson Guillermo Perez-Aragon Alen Ramic Jordan R Ramirez Christopher Scheiber Patrick A Schneider Devon E Schultz Matthew Simon Eric Spencer Adam C Wernette Maxine E Wykle Elizabeth Zavala-Arellano Mitchell J McDonald Kristine Ostby Peter Wendland Justin R DiAngelo Alexis M Ceasrine Amanda H Cox James E B Docherty Robert M Gingras Stephanie M Grieb Michael J Pavia Casey L Personius Grzegorz L Polak Dale L Beach Heaven L Cerritos Edward A Horansky Karim A Sharif Ryan Moran Susan Parrish Kirsten Bickford Jennifer Bland Juliana Broussard Kerry Campbell Katelynn E Deibel Richard Forka Monika C Lemke Marlee B Nelson Catherine O'Keeffe S Mariel Ramey Luke Schmidt Paola Villegas Christopher J Jones Stephanie L Christ Sami Mamari Adam S Rinaldi Ghazal Stity Amy T Hark Mark Scheuerman S Catherine Silver Key Briana D McRae Adam S Haberman Sam Asinof Harriette Carrington Kelly Drumm Terrance Embry Richard McGuire Drew Miller-Foreman Stella Rosen Nadia Safa Darrin Schultz Matt Segal Yakov Shevin Petros Svoronos Tam Vuong Gary Skuse Don W Paetkau Rachael K Bridgman Charlotte M Brown Alicia R Carroll Francesca M Gifford Julie Beth Gillespie Susan E Herman Krystal L Holtcamp Misha A Host Gabrielle Hussey Danielle M Kramer Joan Q Lawrence Madeline M Martin Ellen N Niemiec Ashleigh P O'Reilly Olivia A Pahl Guadalupe Quintana Elizabeth A S Rettie Torie L Richardson Arianne E Rodriguez Mona O Rodriguez Laura Schiraldi Joanna J Smith Kelsey F Sugrue Lindsey J Suriano Kaitlyn E Takach Arielle M Vasquez Ximena Velez Elizabeth J Villafuerte Laura T Vives Victoria R Zellmer Jeanette Hauke Charles R Hauser Karolyn Barker Laurie Cannon Perouza Parsamian Samantha Parsons Zachariah Wichman Christopher W Bazinet Diana E Johnson Abubakarr Bangura Jordan A Black Victoria Chevee Sarah A Einsteen Sarah K Hilton Max Kollmer Rahul Nadendla Joyce Stamm Antoinette E Fafara-Thompson Amber M Gygi Emmy E Ogawa Matt Van Camp Zuzana Kocsisova Judith L Leatherman Cassie M Modahl Michael R Rubin Susana S Apiz-Saab Suzette M Arias-Mejias Carlos F Carrion-Ortiz Patricia N Claudio-Vazquez Debbie M Espada-Green Marium Feliciano-Camacho Karina M Gonzalez-Bonilla Mariela Taboas-Arroyo Dorianmarie Vargas-Franco Raquel Montañez-Gonzalez Joseph Perez-Otero Myrielis Rivera-Burgos Francisco J Rivera-Rosario Heather L Eisler Jackie Alexander Samatha K Begley Deana Gabbard Robert J Allen Wint Yan Aung William D Barshop Amanda Boozalis Vanessa P Chu Jeremy S Davis Ryan N Duggal Robert Franklin Katherine Gavinski Heran Gebreyesus Henry Z Gong Rachel A Greenstein Averill D Guo Casey Hanson Kaitlin E Homa Simon C Hsu Yi Huang Lucy Huo Sarah Jacobs Sasha Jia Kyle L Jung Sarah Wai-Chee Kong Matthew R Kroll Brandon M Lee Paul F Lee Kevin M Levine Amy S Li Chengyu Liu Max Mian Liu Adam P Lousararian Peter B Lowery Allyson P Mallya Joseph E Marcus Patrick C Ng Hien P Nguyen Ruchik Patel Hashini Precht Suchita Rastogi Jonathan M Sarezky Adam Schefkind Michael B Schultz Delia Shen Tara Skorupa Nicholas C Spies Gabriel Stancu Hiu Man Vivian Tsang Alice L Turski Rohit Venkat Leah E Waldman Kaidi Wang Tracy Wang Jeffrey W Wei Dennis Y Wu David D Xiong Jack Yu Karen Zhou Gerard P McNeil Robert W Fernandez Patrick Gomez Menzies Tingting Gu Jeremy Buhler Elaine R Mardis Sarah C R Elgin

G3 (Bethesda) 2017 08 7;7(8):2439-2460. Epub 2017 Aug 7.

Department of Biology, Washington University in St. Louis, St. Louis, MO 63130.

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http://g3journal.org/lookup/doi/10.1534/g3.117.040907
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http://dx.doi.org/10.1534/g3.117.040907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555453PMC
August 2017

Neoantigen Discovery in Human Cancers.

Authors:
Elaine R Mardis

Cancer J 2017 Mar/Apr;23(2):97-101

From the Institute for Genomic Medicine, Nationwide Children's Hospital, and The Ohio State University College of Medicine, Columbus, OH.

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http://dx.doi.org/10.1097/PPO.0000000000000248DOI Listing
May 2017

The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis.

Neuron 2017 May;94(3):550-568.e10

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA; Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA; Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.04.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508517PMC
May 2017

DNA sequencing technologies: 2006-2016.

Authors:
Elaine R Mardis

Nat Protoc 2017 Feb 5;12(2):213-218. Epub 2017 Jan 5.

McDonnell Genome Institute, Washington University, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/nprot.2016.182DOI Listing
February 2017

Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune Escape.

Cancer Immunol Res 2017 02 10;5(2):106-117. Epub 2017 Jan 10.

Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri.

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http://dx.doi.org/10.1158/2326-6066.CIR-16-0391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510474PMC
February 2017

Applications of Immunogenomics to Cancer.

Cell 2017 02;168(4):600-612

Institute for Genomic Medicine, Nationwide Children's Hospital, and The Ohio State University College of Medicine, 575 Children's Crossroad, Columbus OH 43205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5972371PMC
February 2017

Cancer Genomics: Large-Scale Projects Translate into Therapeutic Advances.

PLoS Med 2016 Dec 27;13(12):e1002209. Epub 2016 Dec 27.

Department of Pathology and Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189932PMC
December 2016

Rare Variation in TET2 Is Associated with Clinically Relevant Prostate Carcinoma in African Americans.

Cancer Epidemiol Biomarkers Prev 2016 11 2;25(11):1456-1463. Epub 2016 Aug 2.

Division of Urology, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093030PMC
November 2016

Visualizing tumor evolution with the fishplot package for R.

BMC Genomics 2016 11 7;17(1):880. Epub 2016 Nov 7.

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, 63108, USA.

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http://dx.doi.org/10.1186/s12864-016-3195-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100182PMC
November 2016

Truncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas.

Cell Rep 2016 09;17(1):249-260

McDonnell Genome Institute, Washington University School of Medicine, 4444 Forest Park Ave., St. Louis, MO 63108, USA; Department of Medicine, Washington University School of Medicine, 660 S Euclid Ave., St. Louis, MO 63110, USA; Siteman Cancer Center, Washington University School of Medicine, 4921 Parkview Pl., St. Louis, MO 63110, USA; Department of Genetics, Washington University School of Medicine, 660 S Euclid Ave., St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.08.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557050PMC
September 2016

Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers.

Dis Model Mech 2016 07 5;9(7):749-57. Epub 2016 May 5.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC 27599, USA Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA

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http://dx.doi.org/10.1242/dmm.025239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958311PMC
July 2016

Clinical and Genetic Risk Factors for Acute Pancreatitis in Patients With Acute Lymphoblastic Leukemia.

J Clin Oncol 2016 06 25;34(18):2133-40. Epub 2016 Apr 25.

Chengcheng Liu, Wenjian Yang, Cheng Cheng, Deqing Pei, Colton Smith, Sima Jeha, Ching-Hon Pui, William E. Evans, and Mary V. Relling, St Jude Children's Research Hospital; Scott C. Howard, University of Memphis, Memphis, TN; Meenakshi Devidas, University of Florida, Gainesville, FL; William L. Carroll, New York University Langone Medical Center, New York, NY; Elizabeth A. Raetz, University of Utah, Salt Lake City, UT; W. Paul Bowman, Cook Children's Hospital, Ft Worth; Naomi J. Winick, University of Texas Southwestern Medical Center, Dallas, TX; Eric C. Larsen, Maine Children's Cancer Program, Scarborough, ME; Kelly W. Maloney, University of Colorado Denver, Aurora, CO; Paul L. Martin, Duke University, Durham, NC; Leonard A. Mattano Jr, HARP Pharma Consulting, Mystic, CT; Elaine R. Mardis and Robert S. Fulton, The McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO; Deepa Bhojwani, Children's Hospital of Los Angeles, Los Angeles; Mignon L. Loh, University of California San Francisco Medical Center-Parnassus, San Francisco, CA; and Stephen P. Hunger, Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2015.64.5812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962704PMC
June 2016

The challenges of big data.

Authors:
Elaine R Mardis

Dis Model Mech 2016 05;9(5):483-5

McDonnell Genome Institute at Washington University School of Medicine, St Louis, MO 63108, USA

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http://dx.doi.org/10.1242/dmm.025585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892667PMC
May 2016

PGRNseq: a targeted capture sequencing panel for pharmacogenetic research and implementation.

Pharmacogenet Genomics 2016 Apr;26(4):161-168

aDepartment of Genome Sciences, University of Washington, Seattle, Washington bThe Baylor College of Medicine Human Genome Sequencing Center, Houston, Texas cThe Genome Institute at Washington University, St Louis, Missouri, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935646PMC
April 2016

A Vaccine for Cancer?

Sci Am 2016 Apr;314(4):46

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http://dx.doi.org/10.1038/scientificamerican0416-46DOI Listing
April 2016

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.

PLoS One 2015 7;10(4):e0122271. Epub 2015 Apr 7.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122271PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388675PMC
March 2016

California Dreamin': the Future of Genomic Medicine.

Authors:
Elaine R Mardis

Cold Spring Harb Mol Case Stud 2016 Mar;2(2):a000976

Washington University School of Medicine, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1101/mcs.a000976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849850PMC
March 2016

DGIdb 2.0: mining clinically relevant drug-gene interactions.

Nucleic Acids Res 2016 Jan 3;44(D1):D1036-44. Epub 2015 Nov 3.

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63108, USA Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO 63110, USA Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA

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http://dx.doi.org/10.1093/nar/gkv1165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702839PMC
January 2016

pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens.

Genome Med 2016 Jan 29;8(1):11. Epub 2016 Jan 29.

McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA.

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http://dx.doi.org/10.1186/s13073-016-0264-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733280PMC
January 2016

Germline Mutations in Predisposition Genes in Pediatric Cancer.

N Engl J Med 2015 Dec 18;373(24):2336-2346. Epub 2015 Nov 18.

Departments of Computational Biology (J.Z., G.W., M.N.E., D.H., X.M., X.Z., M.R.W., X.C., M.R., A.P., J.B.B., S.W.), Oncology (M.F.W., T.A.G., R.B.M., S.H.-D., R.N., E.Q., A.G., A.S.P., C.-H.P., K.E.N.), and Pathology (T.A.G., M.R.W., S.A.S., D.W.E., C.-H.P., J.R.D.) and the Pediatric Cancer Genome Project (J.Z., M.F.W., G.W., M.N.E., T.A.G., J.E., X.M., D.A.Y., B.V., X.C., R.B.M., S.H.-D., R.N., E.Q., S.A.S., M.R., A.P., J.B.B., S.W., M.S.W., A.G., D.W.E., A.S.P., C.-H.P., K.E.N., J.R.D.), St. Jude Children's Research Hospital, Memphis, TN; and the Department of Genetics and McDonnell Genome Institute, Washington University School of Medicine in St. Louis, St. Louis (L.D., E.R.M., R.K.W.).

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December 2015

Caenorhabditis elegans glp-4 Encodes a Valyl Aminoacyl tRNA Synthetase.

G3 (Bethesda) 2015 Oct 13;5(12):2719-28. Epub 2015 Oct 13.

Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63110

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October 2015

From "N of 1" to N of more.

Cold Spring Harb Mol Case Stud 2015 Oct;1(1):a000521

Washington University School of Medicine, St. Louis, Missouri 63108, USA.

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October 2015

Optimizing cancer genome sequencing and analysis.

Cell Syst 2015 Sep;1(3):210-223

The McDonnell Genome Institute, Washington University, St. Louis, MO, USA, 63108 ; Department of Genetics, Washington University, St. Louis, MO, USA, 63108 ; Siteman Cancer Center, Washington University, St. Louis, MO, USA, 63108 ; Department of Medicine, Washington University, St. Louis, MO, USA, 63108.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669575PMC
September 2015

Genome Modeling System: A Knowledge Management Platform for Genomics.

PLoS Comput Biol 2015 Jul 9;11(7):e1004274. Epub 2015 Jul 9.

The Genome Institute, Washington University in St. Louis, St. Louis, Missouri, United States of America; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, United States of America; Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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July 2015

Association of Somatic Mutations of ADAMTS Genes With Chemotherapy Sensitivity and Survival in High-Grade Serous Ovarian Carcinoma.

JAMA Oncol 2015 Jul;1(4):486-94

Department of Pathology, University of Texas MD Anderson Cancer Center, Houston2Institute for Systems Biology/MD Anderson Cancer Center Genome Data Analysis Center, The Cancer Genome Atlas, Bethesda, Maryland.

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July 2015

Where Next for Genetics and Genomics?

PLoS Biol 2015 Jul 30;13(7):e1002216. Epub 2015 Jul 30.

The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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July 2015

Xenografts as models of clonal selection and acquired resistance to therapy.

Authors:
Elaine R Mardis

Clin Chem 2015 May 2;61(5):769-70. Epub 2015 Mar 2.

The Genome Institute, Washington University School of Medicine, St. Louis MO.

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May 2015

Drosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.

Authors:
Wilson Leung Christopher D Shaffer Laura K Reed Sheryl T Smith William Barshop William Dirkes Matthew Dothager Paul Lee Jeannette Wong David Xiong Han Yuan James E J Bedard Joshua F Machone Seantay D Patterson Amber L Price Bryce A Turner Srebrenka Robic Erin K Luippold Shannon R McCartha Tezin A Walji Chelsea A Walker Kenneth Saville Marita K Abrams Andrew R Armstrong William Armstrong Robert J Bailey Chelsea R Barberi Lauren R Beck Amanda L Blaker Christopher E Blunden Jordan P Brand Ethan J Brock Dana W Brooks Marie Brown Sarah C Butzler Eric M Clark Nicole B Clark Ashley A Collins Rebecca J Cotteleer Peterson R Cullimore Seth G Dawson Carter T Docking Sasha L Dorsett Grace A Dougherty Kaitlyn A Downey Andrew P Drake Erica K Earl Trevor G Floyd Joshua D Forsyth Jonathan D Foust Spencer L Franchi James F Geary Cynthia K Hanson Taylor S Harding Cameron B Harris Jonathan M Heckman Heather L Holderness Nicole A Howey Dontae A Jacobs Elizabeth S Jewell Maria Kaisler Elizabeth A Karaska James L Kehoe Hannah C Koaches Jessica Koehler Dana Koenig Alexander J Kujawski Jordan E Kus Jennifer A Lammers Rachel R Leads Emily C Leatherman Rachel N Lippert Gregory S Messenger Adam T Morrow Victoria Newcomb Haley J Plasman Stephanie J Potocny Michelle K Powers Rachel M Reem Jonathan P Rennhack Katherine R Reynolds Lyndsey A Reynolds Dong K Rhee Allyson B Rivard Adam J Ronk Meghan B Rooney Lainey S Rubin Luke R Salbert Rasleen K Saluja Taylor Schauder Allison R Schneiter Robert W Schulz Karl E Smith Sarah Spencer Bryant R Swanson Melissa A Tache Ashley A Tewilliager Amanda K Tilot Eve VanEck Matthew M Villerot Megan B Vylonis David T Watson Juliana A Wurzler Lauren M Wysocki Monica Yalamanchili Matthew A Zaborowicz Julia A Emerson Carlos Ortiz Frederic J Deuschle Lauren A DiLorenzo Katie L Goeller Christopher R Macchi Sarah E Muller Brittany D Pasierb Joseph E Sable Jessica M Tucci Marykathryn Tynon David A Dunbar Levent H Beken Alaina C Conturso Benjamin L Danner Gabriella A DeMichele Justin A Gonzales Maureen S Hammond Colleen V Kelley Elisabeth A Kelly Danielle Kulich Catherine M Mageeney Nikie L McCabe Alyssa M Newman Lindsay A Spaeder Richard A Tumminello Dennis Revie Jonathon M Benson Michael C Cristostomo Paolo A DaSilva Katherine S Harker Jenifer N Jarrell Luis A Jimenez Brandon M Katz William R Kennedy Kimberly S Kolibas Mark T LeBlanc Trung T Nguyen Daniel S Nicolas Melissa D Patao Shane M Patao Bryan J Rupley Bridget J Sessions Jennifer A Weaver Anya L Goodman Erica L Alvendia Shana M Baldassari Ashley S Brown Ian O Chase Maida Chen Scott Chiang Avery B Cromwell Ashley F Custer Tia M DiTommaso Jad El-Adaimi Nora C Goscinski Ryan A Grove Nestor Gutierrez Raechel S Harnoto Heather Hedeen Emily L Hong Barbara L Hopkins Vilma F Huerta Colin Khoshabian Kristin M LaForge Cassidy T Lee Benjamin M Lewis Anniken M Lydon Brian J Maniaci Ryan D Mitchell Elaine V Morlock William M Morris Priyanka Naik Nicole C Olson Jeannette M Osterloh Marcos A Perez Jonathan D Presley Matt J Randazzo Melanie K Regan Franca G Rossi Melanie A Smith Eugenia A Soliterman Ciani J Sparks Danny L Tran Tiffany Wan Anne A Welker Jeremy N Wong Aparna Sreenivasan Jim Youngblom Andrew Adams Justin Alldredge Ashley Bryant David Carranza Alyssa Cifelli Kevin Coulson Calise Debow Noelle Delacruz Charlene Emerson Cassandra Farrar Don Foret Edgar Garibay John Gooch Michelle Heslop Sukhjit Kaur Ambreen Khan Van Kim Travis Lamb Peter Lindbeck Gabi Lucas Elizabeth Macias Daniela Martiniuc Lissett Mayorga Joseph Medina Nelson Membreno Shady Messiah Lacey Neufeld San Francisco Nguyen Zachary Nichols George Odisho Daymon Peterson Laura Rodela Priscilla Rodriguez Vanessa Rodriguez Jorge Ruiz Will Sherrill Valeria Silva Jeri Sparks Geeta Statton Ashley Townsend Isabel Valdez Mary Waters Kyle Westphal Stacey Winkler Joannee Zumkehr Randall J DeJong Arlene J Hoogewerf Cheri M Ackerman Isaac O Armistead Lara Baatenburg Matthew J Borr Lindsay K Brouwer Brandon J Burkhart Kelsey T Bushhouse Lejla Cesko Tiffany Y Y Choi Heather Cohen Amanda M Damsteegt Jess M Darusz Cory M Dauphin Yelena P Davis Emily J Diekema Melissa Drewry Michelle E M Eisen Hayley M Faber Katherine J Faber Elizabeth Feenstra Isabella T Felzer-Kim Brandy L Hammond Jesse Hendriksma Milton R Herrold Julia A Hilbrands Emily J Howell Sarah A Jelgerhuis Timothy R Jelsema Benjamin K Johnson Kelly K Jones Anna Kim Ross D Kooienga Erika E Menyes Eric A Nollet Brittany E Plescher Lindsay Rios Jenny L Rose Allison J Schepers Geoff Scott Joshua R Smith Allison M Sterling Jenna C Tenney Chris Uitvlugt Rachel E VanDyken Marielle VanderVennen Samantha Vue Nighat P Kokan Kwabea Agbley Sampson K Boham Daniel Broomfield Kayla Chapman Ali Dobbe Ian Dobbe William Harrington Marwan Ibrahem Andre Kennedy Chad A Koplinsky Cassandra Kubricky Danielle Ladzekpo Claire Pattison Roman E Ramirez Lucia Wande Sarah Woehlke Matthew Wawersik Elizabeth Kiernan Jeffrey S Thompson Roxanne Banker Justina R Bartling Chinmoy I Bhatiya Anna L Boudoures Lena Christiansen Daniel S Fosselman Kristin M French Ishwar S Gill Jessen T Havill Jaelyn L Johnson Lauren J Keny John M Kerber Bethany M Klett Christina N Kufel Francis J May Jonathan P Mecoli Callie R Merry Lauren R Meyer Emily G Miller Gregory J Mullen Katherine C Palozola Jacob J Pfeil Jessica G Thomas Evan M Verbofsky Eric P Spana Anant Agarwalla Julia Chapman Ben Chlebina Insun Chong I N Falk John D Fitzgibbons Harrison Friedman Osagie Ighile Andrew J Kim Kristin A Knouse Faith Kung Danny Mammo Chun Leung Ng Vinayak S Nikam Diana Norton Philip Pham Jessica W Polk Shreya Prasad Helen Rankin Camille D Ratliff Victoria Scala Nicholas U Schwartz Jessica A Shuen Amy Xu Thomas Q Xu Yi Zhang Anne G Rosenwald Martin G Burg Stephanie J Adams Morgan Baker Bobbi Botsford Briana Brinkley Carter Brown Shadie Emiah Erica Enoch Chad Gier Alyson Greenwell Lindsay Hoogenboom Jordan E Matthews Mitchell McDonald Amanda Mercer Nicholaus Monsma Kristine Ostby Alen Ramic Devon Shallman Matthew Simon Eric Spencer Trisha Tomkins Pete Wendland Anna Wylie Michael J Wolyniak Gregory M Robertson Samuel I Smith Justin R DiAngelo Eric D Sassu Satish C Bhalla Karim A Sharif Tenzin Choeying Jason S Macias Fareed Sanusi Karvyn Torchon April E Bednarski Consuelo J Alvarez Kristen C Davis Carrie A Dunham Alaina J Grantham Amber N Hare Jennifer Schottler Zackary W Scott Gary A Kuleck Nicole S Yu Marian M Kaehler Jacob Jipp Paul J Overvoorde Elizabeth Shoop Olivia Cyrankowski Betsy Hoover Matt Kusner Devry Lin Tijana Martinov Jonathan Misch Garrett Salzman Holly Schiedermayer Michael Snavely Stephanie Zarrasola Susan Parrish Atlee Baker Alissa Beckett Carissa Belella Julie Bryant Turner Conrad Adam Fearnow Carolina Gomez Robert A Herbstsomer Sarah Hirsch Christen Johnson Melissa Jones Rita Kabaso Eric Lemmon Carolina Marques Dos Santos Vieira Darryl McFarland Christopher McLaughlin Abbie Morgan Sepo Musokotwane William Neutzling Jana Nietmann Christina Paluskievicz Jessica Penn Emily Peoples Caitlin Pozmanter Emily Reed Nichole Rigby Lasse Schmidt Micah Shelton Rebecca Shuford Tiara Tirasawasdichai Blair Undem Damian Urick Kayla Vondy Bryan Yarrington Todd T Eckdahl Jeffrey L Poet Alica B Allen John E Anderson Jason M Barnett Jordan S Baumgardner Adam D Brown Jordan E Carney Ramiro A Chavez Shelbi L Christgen Jordan S Christie Andrea N Clary Michel A Conn Kristen M Cooper Matt J Crowley Samuel T Crowley Jennifer S Doty Brian A Dow Curtis R Edwards Darcie D Elder John P Fanning Bridget M Janssen Anthony K Lambright Curtiss E Lane Austin B Limle Tammy Mazur Marly R McCracken Alexa M McDonough Amy D Melton Phillip J Minnick Adam E Musick William H Newhart Joseph W Noynaert Bradley J Ogden Michael W Sandusky Samantha M Schmuecker Anna L Shipman Anna L Smith Kristen M Thomsen Matthew R Unzicker William B Vernon Wesley W Winn Dustin S Woyski Xiao Zhu Chunguang Du Caitlin Ament Soham Aso Laura Simone Bisogno Jason Caronna Nadezhda Fefelova Lenin Lopez Lorraine Malkowitz Jonathan Marra Daniella Menillo Ifeanyi Obiorah Eric Nyabeta Onsarigo Shekerah Primus Mahdi Soos Archana Tare Ameer Zidan Christopher J Jones Todd Aronhalt James M Bellush Christa Burke Steve DeFazio Benjamin R Does Todd D Johnson Nicholas Keysock Nelson H Knudsen James Messler Kevin Myirski Jade Lea Rekai Ryan Michael Rempe Michael S Salgado Erica Stagaard Justin R Starcher Andrew W Waggoner Anastasia K Yemelyanova Amy T Hark Anne Bertolet Cyrus E Kuschner Kesley Parry Michael Quach Lindsey Shantzer Mary E Shaw Mary A Smith Omolara Glenn Portia Mason Charlotte Williams S Catherine Silver Key Tyneshia C P Henry Ashlee G Johnson Jackie X White Adam Haberman Sam Asinof Kelly Drumm Trip Freeburg Nadia Safa Darrin Schultz Yakov Shevin Petros Svoronos Tam Vuong Jules Wellinghoff Laura L M Hoopes Kim M Chau Alyssa Ward E Gloria C Regisford LaJerald Augustine Brionna Davis-Reyes Vivienne Echendu Jasmine Hales Sharon Ibarra Lauriaun Johnson Steven Ovu John M Braverman Thomas J Bahr Nicole M Caesar Christopher Campana Daniel W Cassidy Peter A Cognetti Johnathan D English Matthew C Fadus Cameron N Fick Philip J Freda Bryan M Hennessy Kelsey Hockenberger Jennifer K Jones Jessica E King Christopher R Knob Karen J Kraftmann Linghui Li Lena N Lupey Carl J Minniti Thomas F Minton Joseph V Moran Krishna Mudumbi Elizabeth C Nordman William J Puetz Lauren M Robinson Thomas J Rose Edward P Sweeney Ashley S Timko Don W Paetkau Heather L Eisler Megan E Aldrup Jessica M Bodenberg Mara G Cole Kelly M Deranek Megan DeShetler Rose M Dowd Alexandra K Eckardt Sharon C Ehret Jessica Fese Amanda D Garrett Anna Kammrath Michelle L Kappes Morgan R Light Anne C Meier Allison O'Rouke Mallory Perella Kimberley Ramsey Jennifer R Ramthun Mary T Reilly Deirdre Robinett Nadine L Rossi Mary Grace Schueler Emma Shoemaker Kristin M Starkey Ashley Vetor Abby Vrable Vidya Chandrasekaran Christopher Beck Kristen R Hatfield Douglas A Herrick Christopher B Khoury Charlotte Lea Christopher A Louie Shannon M Lowell Thomas J Reynolds Jeanine Schibler Alexandra H Scoma Maxwell T Smith-Gee Sarah Tuberty Christopher D Smith Jane E Lopilato Jeanette Hauke Jennifer A Roecklein-Canfield Maureen Corrielus Hannah Gilman Stephanie Intriago Amanda Maffa Sabya A Rauf Katrina Thistle Melissa Trieu Jenifer Winters Bib Yang Charles R Hauser Tariq Abusheikh Yara Ashrawi Pedro Benitez Lauren R Boudreaux Megan Bourland Miranda Chavez Samantha Cruz GiNell Elliott Jesse R Farek Sarah Flohr Amanda H Flores Chelsey Friedrichs Zach Fusco Zane Goodwin Eric Helmreich John Kiley John Mark Knepper Christine Langner Megan Martinez Carlos Mendoza Monal Naik Andrea Ochoa Nicolas Ragland England Raimey Sunil Rathore Evangelina Reza Griffin Sadovsky Marie-Isabelle B Seydoux Jonathan E Smith Anna K Unruh Vicente Velasquez Matthew W Wolski Yuying Gosser Shubha Govind Nicole Clarke-Medley Leslie Guadron Dawn Lau Alvin Lu Cheryl Mazzeo Mariam Meghdari Simon Ng Brad Pamnani Olivia Plante Yuki Kwan Wa Shum Roy Song Diana E Johnson Mai Abdelnabi Alexi Archambault Norma Chamma Shailly Gaur Deborah Hammett Adrese Kandahari Guzal Khayrullina Sonali Kumar Samantha Lawrence Nigel Madden Max Mandelbaum Heather Milnthorp Shiv Mohini Roshni Patel Sarah J Peacock Emily Perling Amber Quintana Michael Rahimi Kristen Ramirez Rishi Singhal Corinne Weeks Tiffany Wong Aubree T Gillis Zachary D Moore Christopher D Savell Reece Watson Stephanie F Mel Arjun A Anilkumar Paul Bilinski Rostislav Castillo Michael Closser Nathalia M Cruz Tiffany Dai Giancarlo F Garbagnati Lanor S Horton Dongyeon Kim Joyce H Lau James Z Liu Sandy D Mach Thu A Phan Yi Ren Kenneth E Stapleton Jean M Strelitz Ray Sunjed Joyce Stamm Morgan C Anderson Bethany Grace Bonifield Daniel Coomes Adam Dillman Elaine J Durchholz Antoinette E Fafara-Thompson Meleah J Gross Amber M Gygi Lesley E Jackson Amy Johnson Zuzana Kocsisova Joshua L Manghelli Kylie McNeil Michael Murillo Kierstin L Naylor Jessica Neely Emmy E Ogawa Ashley Rich Anna Rogers J Devin Spencer Kristina M Stemler Allison A Throm Matt Van Camp Katie Weihbrecht T Aaron Wiles Mallory A Williams Matthew Williams Kyle Zoll Cheryl Bailey Leming Zhou Darla M Balthaser Azita Bashiri Mindy E Bower Kayla A Florian Nazanin Ghavam Elizabeth S Greiner-Sosanko Helmet Karim Victor W Mullen Carly E Pelchen Paul M Yenerall Jiayu Zhang Michael R Rubin Suzette M Arias-Mejias Armando G Bermudez-Capo Gabriela V Bernal-Vega Mariela Colon-Vazquez Arelys Flores-Vazquez Mariela Gines-Rosario Ivan G Llavona-Cartagena Javier O Martinez-Rodriguez Lionel Ortiz-Fuentes Eliezer O Perez-Colomba Joseph Perez-Otero Elisandra Rivera Luke J Rodriguez-Giron Arnaldo J Santiago-Sanabria Andrea M Senquiz-Gonzalez Frank R Soto delValle Dorianmarie Vargas-Franco Karla I Velázquez-Soto Joan D Zambrana-Burgos Juan Carlos Martinez-Cruzado Lillyann Asencio-Zayas Kevin Babilonia-Figueroa Francis D Beauchamp-Pérez Juliana Belén-Rodríguez Luciann Bracero-Quiñones Andrea P Burgos-Bula Xavier A Collado-Méndez Luis R Colón-Cruz Ana I Correa-Muller Jonathan L Crooke-Rosado José M Cruz-García Marianna Defendini-Ávila Francheska M Delgado-Peraza Alex J Feliciano-Cancela Valerie M Gónzalez-Pérez Wilfried Guiblet Aldo Heredia-Negrón Jennifer Hernández-Muñiz Lourdes N Irizarry-González Ángel L Laboy-Corales Gabriela A Llaurador-Caraballo Frances Marín-Maldonado Ulises Marrero-Llerena Héctor A Martell-Martínez Idaliz M Martínez-Traverso Kiara N Medina-Ortega Sonya G Méndez-Castellanos Krizia C Menéndez-Serrano Carol I Morales-Caraballo Saryleine Ortiz-DeChoudens Patricia Ortiz-Ortiz Hendrick Pagán-Torres Diana Pérez-Afanador Enid M Quintana-Torres Edwin G Ramírez-Aponte Carolina Riascos-Cuero Michelle S Rivera-Llovet Ingrid T Rivera-Pagán Ramón E Rivera-Vicéns Fabiola Robles-Juarbe Lorraine Rodríguez-Bonilla Brian O Rodríguez-Echevarría Priscila M Rodríguez-García Abneris E Rodríguez-Laboy Susana Rodríguez-Santiago Michael L Rojas-Vargas Eva N Rubio-Marrero Albeliz Santiago-Colón Jorge L Santiago-Ortiz Carlos E Santos-Ramos Joseline Serrano-González Alina M Tamayo-Figueroa Edna P Tascón-Peñaranda José L Torres-Castillo Nelson A Valentín-Feliciano Yashira M Valentín-Feliciano Nadyan M Vargas-Barreto Miguel Vélez-Vázquez Luis R Vilanova-Vélez Cristina Zambrana-Echevarría Christy MacKinnon Hui-Min Chung Chris Kay Anthony Pinto Olga R Kopp Joshua Burkhardt Chris Harward Robert Allen Pavan Bhat Jimmy Hsiang-Chun Chang York Chen Christopher Chesley Dara Cohn David DuPuis Michael Fasano Nicholas Fazzio Katherine Gavinski Heran Gebreyesus Thomas Giarla Marcus Gostelow Rachel Greenstein Hashini Gunasinghe Casey Hanson Amanda Hay Tao Jian He Katie Homa Ruth Howe Jeff Howenstein Henry Huang Aaditya Khatri Young Lu Kim Olivia Knowles Sarah Kong Rebecca Krock Matt Kroll Julia Kuhn Matthew Kwong Brandon Lee Ryan Lee Kevin Levine Yedda Li Bo Liu Lucy Liu Max Liu Adam Lousararian Jimmy Ma Allyson Mallya Charlie Manchee Joseph Marcus Stephen McDaniel Michelle L Miller Jerome M Molleston Cristina Montero Diez Patrick Ng Natalie Ngai Hien Nguyen Andrew Nylander Jason Pollack Suchita Rastogi Himabindu Reddy Nathaniel Regenold Jon Sarezky Michael Schultz Jien Shim Tara Skorupa Kenneth Smith Sarah J Spencer Priya Srikanth Gabriel Stancu Andrew P Stein Marshall Strother Lisa Sudmeier Mengyang Sun Varun Sundaram Noor Tazudeen Alan Tseng Albert Tzeng Rohit Venkat Sandeep Venkataram Leah Waldman Tracy Wang Hao Yang Jack Y Yu Yin Zheng Mary L Preuss Angelica Garcia Matt Juergens Robert W Morris Alexis A Nagengast Julie Azarewicz Thomas J Carr Nicole Chichearo Mike Colgan Megan Donegan Bob Gardner Nik Kolba Janice L Krumm Stacey Lytle Laurell MacMillian Mary Miller Andrew Montgomery Alysha Moretti Brittney Offenbacker Mike Polen John Toth John Woytanowski Lisa Kadlec Justin Crawford Mary L Spratt Ashley L Adams Brianna K Barnard Martin N Cheramie Anne M Eime Kathryn L Golden Allyson P Hawkins Jessica E Hill Jessica A Kampmeier Cody D Kern Emily E Magnuson Ashley R Miller Cody M Morrow Julia C Peairs Gentry L Pickett Sarah A Popelka Alexis J Scott Emily J Teepe Katie A TerMeer Carmen A Watchinski Lucas A Watson Rachel E Weber Kate A Woodard Daron C Barnard Isaac Appiah Michelle M Giddens Gerard P McNeil Adeola Adebayo Kate Bagaeva Justina Chinwong Chrystel Dol Eunice George Kirk Haltaufderhyde Joanna Haye Manpreet Kaur Max Semon Dmitri Serjanov Anika Toorie Christopher Wilson Nicole C Riddle Jeremy Buhler Elaine R Mardis Sarah C R Elgin

G3 (Bethesda) 2015 Mar 4;5(5):719-40. Epub 2015 Mar 4.

Department of Biology, Washington University in St. Louis, St. Louis, MO 63130

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http://g3journal.org/cgi/doi/10.1534/g3.114.015966
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March 2015

Exome sequencing of case-unaffected-parents trios reveals recessive and de novo genetic variants in sporadic ALS.

Sci Rep 2015 Mar 16;5:9124. Epub 2015 Mar 16.

The Stacey MND Laboratory, Department of Pathology, The University of Sydney, Sydney, New South Wales, Australia.

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March 2015

Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nat Med 2014 Dec 19;20(12):1472-8. Epub 2014 Oct 19.

1] The Genome Institute, Washington University in St. Louis, St. Louis, Missouri, USA. [2] Department of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA. [3] Department of Genetics, Washington University in St. Louis, St. Louis, Missouri, USA. [4] Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, USA.

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December 2014

Estrogen receptor expression is high but is of lower intensity in tubular carcinoma than in well-differentiated invasive ductal carcinoma.

Arch Pathol Lab Med 2014 Nov;138(11):1507-13

From the Department of Pathology (Drs Jorns and Thomas) and Comprehensive Cancer Center (Mr Healy and Ms Daignault), University of Michigan, Ann Arbor; the Genome Institute (Ms Vickery and Dr Mardis) and Division of Oncology (Ms Snider and Drs Davies and Ellis), Washington University School of Medicine, St Louis, Missouri; and the Department of Laboratory Medicine and Pathology (Dr Visscher), Mayo Medical Laboratories, Rochester, Minnesota.

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November 2014

Sequencing the AML genome, transcriptome, and epigenome.

Authors:
Elaine R Mardis

Semin Hematol 2014 Oct 7;51(4):250-8. Epub 2014 Aug 7.

The Genome Institute, Washington University School of Medicine, St. Louis, MO. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316686PMC
October 2014