Elaine Johnstone

Elaine Johnstone

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Elaine Johnstone

Elaine Johnstone

Publications by authors named "Elaine Johnstone"

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Association analyses identify 31 new risk loci for colorectal cancer susceptibility.

Nat Commun 2019 05 14;10(1):2154. Epub 2019 May 14.

Colon Cancer Genetics Group, Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, University of Edinburgh, Edinburgh, EH4 2XU, UK.

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http://www.nature.com/articles/s41467-019-09775-w
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http://dx.doi.org/10.1038/s41467-019-09775-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517433PMC
May 2019

Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series.

Lancet Gastroenterol Hepatol 2018 09 2;3(9):635-643. Epub 2018 Jul 2.

Oxford Centre for Cancer Gene Research, Wellcome Trust Centre for Human Genetics, Oxford, UK; Genomic Medicine Theme, National Institute for Health Research Oxford Biomedical Research Centre, Wellcome Trust Centre for Human Genetics, Oxford, UK; Cancer Genetics and Evolution Laboratory, Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, UK.

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http://dx.doi.org/10.1016/S2468-1253(18)30117-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6088509PMC
September 2018

The value of additional bevacizumab in patients with high-risk stroma-high colon cancer. A study within the QUASAR2 trial, an open-label randomized phase 3 trial.

J Surg Oncol 2018 Apr 15;117(5):1043-1048. Epub 2018 Feb 15.

Department of Surgery, Leiden Universal Medical Centre (LUMC), Leiden, The Netherlands.

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http://dx.doi.org/10.1002/jso.24998DOI Listing
April 2018

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

Authors:
Tae-Hwi Schwantes-An Juan Zhang Li-Shiun Chen Sarah M Hartz Robert C Culverhouse Xiangning Chen Hilary Coon Josef Frank Helen M Kamens Bettina Konte Leena Kovanen Antti Latvala Lisa N Legrand Brion S Maher Whitney E Melroy Elliot C Nelson Mark W Reid Jason D Robinson Pei-Hong Shen Bao-Zhu Yang Judy A Andrews Paul Aveyard Olga Beltcheva Sandra A Brown Dale S Cannon Sven Cichon Robin P Corley Norbert Dahmen Louisa Degenhardt Tatiana Foroud Wolfgang Gaebel Ina Giegling Stephen J Glatt Richard A Grucza Jill Hardin Annette M Hartmann Andrew C Heath Stefan Herms Colin A Hodgkinson Per Hoffmann Hyman Hops David Huizinga Marcus Ising Eric O Johnson Elaine Johnstone Radka P Kaneva Kenneth S Kendler Falk Kiefer Henry R Kranzler Ken S Krauter Orna Levran Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Nicholas G Martin Manuel Mattheisen Grant W Montgomery Bertram Müller-Myhsok Michael F Murphy Michael C Neale Momchil A Nikolov Denise Nishita Markus M Nöthen John Nurnberger Timo Partonen Michele L Pergadia Maureen Reynolds Monika Ridinger Richard J Rose Noora Rouvinen-Lagerström Norbert Scherbaum Christine Schmäl Michael Soyka Michael C Stallings Michael Steffens Jens Treutlein Ming Tsuang Tamara L Wall Norbert Wodarz Vadim Yuferov Peter Zill Andrew W Bergen Jingchun Chen Paul M Cinciripini Howard J Edenberg Marissa A Ehringer Robert E Ferrell Joel Gelernter David Goldman John K Hewitt Christian J Hopfer William G Iacono Jaakko Kaprio Mary Jeanne Kreek Ivo M Kremensky Pamela A F Madden Matt McGue Marcus R Munafò Robert A Philibert Marcella Rietschel Alec Roy Dan Rujescu Sirkku T Saarikoski Gary E Swan Alexandre A Todorov Michael M Vanyukov Robert B Weiss Laura J Bierut Nancy L Saccone

Behav Genet 2016 Mar 21;46(2):151-69. Epub 2015 Sep 21.

Department of Genetics, Washington University School of Medicine, 4523 Clayton Avenue, Campus Box 8232, St. Louis, MO, 63110, USA.

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https://genepi.qimr.edu.au/contents/p/staff/Schwantes_An_Beh
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http://link.springer.com/10.1007/s10519-015-9737-3
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http://dx.doi.org/10.1007/s10519-015-9737-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752855PMC
March 2016

Differential Efficacy of Nicotine Replacement Among Overweight and Obese Women Smokers.

Nicotine Tob Res 2015 Jul 6;17(7):855-61. Epub 2014 Dec 6.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK; UK Centre for Tobacco and Alcohol Studies and School of Experimental Psychology, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/ntr/ntu256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542679PMC
July 2015

Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis.

J Clin Oncol 2014 Apr 3;32(10):1031-9. Epub 2014 Mar 3.

Dan Rosmarin, Claire Palles, David Church, Enric Domingo, Angela Jones, Ian Tomlinson, Wellcome Trust Centre for Human Genetics, NIHR Comprehensive Biomedical Research Centre, University of Oxford; Dan Rosmarin, David Church, Elaine Johnstone, Haitao Wang, Sharon Love, Patrick Julier, Claire Scudder, George Nicholson, Rachel Midgley, David Kerr, and George Nicholson, University of Oxford, Oxford; Michael Braun, The Christie NHS Foundation Trust, Manchester; Matthew Seymour, St James's University Hospital, Leeds; Lindsay Thompson, Medical Research Council Clinical Trials Unit; Rohini Sharma, Imperial College Healthcare NHS Trust, Hammersmith and Charing Cross Hospitals, London, United Kingdom; Anna Gonzalez-Neira, Spanish National Cancer Research Centre; Miguel Martin, Instituto de Investigacion Sanitaria Hospital General Universitario Gregorio Marañón, Universidad Complutense, Madrid; Nuria Ribelles, Hospital Universitario Virgen de la Victoria, Málaga; Eva Martinez-Balibrea, Institut Català d'Oncologia, Institut de Recerca Sanitària Germans Trias i Pujol, Barcelona; Jesus Garcia-Foncillas, University Clinic of Navarra, University of Navarra, Pamplona, Spain; Daniel Sargent, Erin Green, Mayo Clinic, Rochester, MN; Howard McLeod, University of North Carolina, Chapel Hill, NC; Ulrich M. Zanger, Matthias Schwab, Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Stuttgart; Ulrich M. Zanger, Matthias Schwab, University Hospital Tuebingenl, Tuebingen, Germany; Benjamin Lacas, Valérie Boige, Jean-Pierre Pignon, Institut Gustave Roussy, Villejuif; Marie-Christine Etienne-Grimaldi, Gérard Milano, Centre Antoine Lacassagne, Nice; Thierry Lecomte, Pierre Laurent-Puig, Assistance Publique Hopitaux de Paris, Hopital Européen Georges Pompidou, Paris; Alain Morel, Institut National de la Sante et de la Recherche Medicale U564, Centre Paul Papin, Angers, France; Shoaib Afzal, Henrik Enghusen, Laboratory of Clinical Pharmacology, Rigshospitalet, Copenhagen; Sør

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http://dx.doi.org/10.1200/JCO.2013.51.1857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879695PMC
April 2014

Evaluation of PIK3CA mutation as a predictor of benefit from nonsteroidal anti-inflammatory drug therapy in colorectal cancer.

J Clin Oncol 2013 Dec 23;31(34):4297-305. Epub 2013 Sep 23.

Enric Domingo, David N. Church, Rajarajan Ramamoorthy, and Ian P.M. Tomlinson, The Wellcome Trust Centre for Human Genetics, University of Oxford; David N. Church, David J. Kerr, and Rachel Midgley, Oxford Cancer Centre, Churchill Hospital; Yoko Yanagisawa, Elaine Johnstone, David J. Kerr, and Rachel Midgley, University of Oxford, Oxford; Rajarajan Ramamoorthy and Brian Davidson, University College London, Royal Free Hospital, London, United Kingdom; and Oliver Sieber, Ludwig Colon Cancer Initiative Laboratory, Ludwig Institute for Cancer Research, Melbourne, Victoria, Australia.

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http://jco.ascopubs.org/content/early/2013/09/18/JCO.2013.50
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2013.50.0322
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http://dx.doi.org/10.1200/JCO.2013.50.0322DOI Listing
December 2013

Lack of association of OPRM1 genotype and smoking cessation.

Nicotine Tob Res 2013 Mar 18;15(3):739-44. Epub 2012 Sep 18.

School of Experimental Psychology, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/ntr/nts174DOI Listing
March 2013

Association between nicotinic acetylcholine receptor single nucleotide polymorphisms and smoking cessation.

Nicotine Tob Res 2012 Aug 17;14(8):993-7. Epub 2011 Dec 17.

School of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK.

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https://academic.oup.com/ntr/article-lookup/doi/10.1093/ntr/
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http://dx.doi.org/10.1093/ntr/ntr246DOI Listing
August 2012

Weight change over eight years in relation to alcohol consumption in a cohort of continuing smokers and quitters.

Nicotine Tob Res 2011 Nov 26;13(11):1149-54. Epub 2011 May 26.

UK Centre for Tobacco Control Studies, Primary Care Clinical Sciences, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1093/ntr/ntr092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203131PMC
November 2011

CHRNA3 rs1051730 genotype and short-term smoking cessation.

Nicotine Tob Res 2011 Oct 20;13(10):982-8. Epub 2011 Jun 20.

School of Experimental Psychology, University of Bristol, Bristol, UK.

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https://academic.oup.com/ntr/article-lookup/doi/10.1093/ntr/
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http://dx.doi.org/10.1093/ntr/ntr106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179672PMC
October 2011

Pharmacogenetics of smoking cessation in general practice: results from the patch II and patch in practice trials.

Nicotine Tob Res 2011 Mar 25;13(3):157-67. Epub 2011 Jan 25.

Center for Education and Research in Family and Community Medicine, 1215 Welch Road, Modular G, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1093/ntr/ntq246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107615PMC
March 2011

Associations between weight change over 8 years and baseline body mass index in a cohort of continuing and quitting smokers.

Addiction 2011 Jan 6;106(1):188-96. Epub 2010 Oct 6.

UK Centre for Tobacco Control Studies, Primary Care Clinical Sciences, University of Birmingham, UK.

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http://dx.doi.org/10.1111/j.1360-0443.2010.03136.xDOI Listing
January 2011

What is the role and impact of molecular markers on treatment decisions for colorectal cancer in the adjuvant setting?

Discov Med 2009 Oct;8(42):104-7

Sidra Medical and Research Centre, Qatar Foundation, Doha, Qatar.

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October 2009

Genetic prognostic and predictive markers in colorectal cancer.

Nat Rev Cancer 2009 Jul 18;9(7):489-99. Epub 2009 Jun 18.

Department of Medicine, Royal Marsden Hospital, Downs Road, Sutton, SM2 5PT, UK.

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http://dx.doi.org/10.1038/nrc2645DOI Listing
July 2009

Lack of association of DRD2 rs1800497 (Taq1A) polymorphism with smoking cessation in a nicotine replacement therapy randomized trial.

Nicotine Tob Res 2009 Apr 8;11(4):404-7. Epub 2009 Mar 8.

Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK.

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http://dx.doi.org/10.1093/ntr/ntp007DOI Listing
April 2009

Genetic variation in the serotonin pathway and smoking cessation with nicotine replacement therapy: new data from the Patch in Practice trial and pooled analyses.

Drug Alcohol Depend 2008 Nov 17;98(1-2):77-85. Epub 2008 Jun 17.

Department of Family Medicine, Center for Primary Care & Prevention, The Warren Alpert Medical School of Brown University, 111 Brewster Street, Pawtucket, RI 02806, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2008.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439462PMC
November 2008

Smoking status moderates the association of the dopamine D4 receptor (DRD4) gene VNTR polymorphism with selective processing of smoking-related cues.

Addict Biol 2008 Sep 7;13(3-4):435-9. Epub 2008 Mar 7.

Department of Experimental Psychology, University of Bristol, 12a Priory Road, Bristol BS8 1TU, UK.

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http://dx.doi.org/10.1111/j.1369-1600.2008.00098.xDOI Listing
September 2008

Genes and cigarette smoking.

Addiction 2008 Jun 8;103(6):893-904. Epub 2008 Jan 8.

Department of Experimental Psychology, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1111/j.1360-0443.2007.02071.xDOI Listing
June 2008

A cost-effectiveness analysis of genetic testing of the DRD2 Taq1A polymorphism to aid treatment choice for smoking cessation.

Nicotine Tob Res 2008 Jan;10(1):231-40

Primary Care, Department, Community Based Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1080/14622200701767761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2257987PMC
January 2008

Weekly versus basic smoking cessation support in primary care: a randomised controlled trial.

Thorax 2007 Oct 4;62(10):898-903. Epub 2007 May 4.

Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1136/thx.2006.071837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094265PMC
October 2007

Determinants of the rate of nicotine metabolism and effects on smoking behavior.

Clin Pharmacol Ther 2006 Oct;80(4):319-30

Department of Clinical Pharmacology, Cancer Research UK Medical Statistics Group, Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/j.clpt.2006.06.011DOI Listing
October 2006

Smoking cessation, weight gain, and DRD4 -521 genotype.

Am J Med Genet B Neuropsychiatr Genet 2006 Jun;141B(4):398-402

Department of Experimental Psychology, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.b.30289DOI Listing
June 2006

Neuroticism mediates the association of the serotonin transporter gene with lifetime major depression.

Neuropsychobiology 2006 24;53(1):1-8. Epub 2005 Nov 24.

Department of Experimental Psychology, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1159/000089915DOI Listing
May 2006

Lack of association of 5-HTTLPR genotype with smoking cessation in a nicotine replacement therapy randomized trial.

Cancer Epidemiol Biomarkers Prev 2006 Feb;15(2):398-400

Department of Experimental Psychology, University of Bristol, 8 Woodland Road, Bristol BS8 1TN, United Kingdom.

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http://dx.doi.org/10.1158/1055-9965.EPI-05-0648DOI Listing
February 2006

Association between the serotonin transporter gene and alcohol consumption in social drinkers.

Am J Med Genet B Neuropsychiatr Genet 2005 May;135B(1):10-4

Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.b.30162DOI Listing
May 2005

A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans.

J Neurosci 2005 Mar;25(10):2586-90

Department of Clinical Pharmacology, Cancer Research United Kingdom General Practice Research Group, University of Oxford, Oxford OX2 6HE, United Kingdom.

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http://dx.doi.org/10.1523/JNEUROSCI.3769-04.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1942077PMC
March 2005

Zyban for smoking cessation in a general practice setting: the response to an invitation to make a quit attempt.

Addict Biol 2004 Sep-Dec;9(3-4):227-32

Cancer Research UK General Practice Research Group, Clinical Pharmacology, Oxford University, UK.

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http://dx.doi.org/10.1080/13556210412331312421DOI Listing
February 2005

Identification of CYP2B6 sequence variants by use of multiplex PCR with allele-specific genotyping.

Clin Chem 2004 Aug 3;50(8):1372-7. Epub 2004 Jun 3.

Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1373/clinchem.2004.031708DOI Listing
August 2004

The genetic basis for smoking behavior: a systematic review and meta-analysis.

Nicotine Tob Res 2004 Aug;6(4):583-97

Department of Clinical Pharmacology, University of Oxford, UK.

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http://dx.doi.org/10.1080/14622200410001734030DOI Listing
August 2004

Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1.

Hum Mutat 2004 Jun;23(6):540-5

Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1002/humu.20039DOI Listing
June 2004

Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch.

Pharmacogenetics 2004 Feb;14(2):83-90

Cancer Research UK General Practice Research Group, Department of Clinical Pharmacology, University of Oxford, Oxford, UK.

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February 2004

Polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers: seeking confirmation of the association in a follow-up study.

Pharmacogenetics 2002 Oct;12(7):585-7

Cancer Research UK General Practice Research Group, Institute of Health Sciences, Oxford, UK.

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October 2002

Genetic testing: the future of smoking cessation therapy?

Expert Rev Mol Diagn 2002 Jan;2(1):60-8

ICRF General Practice Research Group, Institute of Health Sciences, Old Road, Oxford, OX3 7LF, UK.

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http://dx.doi.org/10.1586/14737159.2.1.60DOI Listing
January 2002

New directions in the genetic mechanisms underlying nicotine addiction.

Addict Biol 2001 Apr;6(2):109-117

University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1080/13556210020040181DOI Listing
April 2001