Publications by authors named "Elaine I Tuomanen"

56Publications

Mini-Review: Bioactivities of Bacterial Cell Envelopes in the Central Nervous System.

Front Cell Infect Microbiol 2020 26;10:588378. Epub 2020 Oct 26.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcimb.2020.588378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649116PMC
October 2020

Perspective of a Pediatrician: Shared Pathogenesis of the Three Most Successful Pathogens of Children.

Front Cell Infect Microbiol 2020 15;10:585791. Epub 2020 Oct 15.

Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcimb.2020.585791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7593378PMC
October 2020

Pneumolysin: Pathogenesis and Therapeutic Target.

Front Microbiol 2020 2;11:1543. Epub 2020 Jul 2.

Department of Infectious Disease, St. Jude Children's Research Hospital, Memphis, TN, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2020.01543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7343714PMC
July 2020

Caging and COM-Bating Antibiotic Resistance.

Cell Host Microbe 2020 04;27(4):489-490

Department of Infectious Diseases, St Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chom.2020.03.013DOI Listing
April 2020

: Invasion and Inflammation.

Microbiol Spectr 2019 03;7(2)

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105.

View Article

Download full-text PDF

Source
http://www.asmscience.org/content/journal/microbiolspec/10.1
Publisher Site
http://dx.doi.org/10.1128/microbiolspec.GPP3-0004-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422050PMC
March 2019

Pneumococcal neuraminidase activates TGF-β signalling.

Microbiology (Reading) 2017 Aug;163(8):1198-1207

Departments of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://www.microbiologyresearch.org/content/journal/micro/10
Publisher Site
http://dx.doi.org/10.1099/mic.0.000511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817201PMC
August 2017

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy.

Proc Natl Acad Sci U S A 2016 10 26;113(41):E6153-E6161. Epub 2016 Sep 26.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1607787113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068317PMC
October 2016

Host-pathogen interactions in bacterial meningitis.

Acta Neuropathol 2016 Feb 7;131(2):185-209. Epub 2016 Jan 7.

Institute for Microbiology, University of Veterinary Medicine, Bischofsholer Damm 15, 30173, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-015-1531-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713723PMC
February 2016

Blood borne: bacterial components in mother's blood influence fetal development.

Inflamm Cell Signal 2016 ;3(4)

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14800/ics.1421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340199PMC
January 2016

Multivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection.

Clin Vaccine Immunol 2015 Oct 5;22(10):1079-89. Epub 2015 Aug 5.

Research Centre for Infectious Diseases, Department of Molecular and Cellular Biology, University of Adelaide, South Australia, Australia

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/CVI.00293-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580740PMC
October 2015

Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster.

Nat Commun 2014 Nov 12;5:5411. Epub 2014 Nov 12.

1] Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, 243 Charles Street C703, Boston, Massachusetts 02114, USA [2] Department of Microbiology and Immunobiology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA [3] The Broad Institute of MIT and Harvard, 320 Charles Street, Cambridge, Massachusetts 02141, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms6411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231546PMC
November 2014

The pneumococcus: epidemiology, microbiology, and pathogenesis.

Cold Spring Harb Perspect Med 2013 Jul 1;3(7). Epub 2013 Jul 1.

Department of Microbiology, Tumor, and Cell Biology, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a010215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685878PMC
July 2013

Control of virulence by small RNAs in Streptococcus pneumoniae.

PLoS Pathog 2012 12;8(7):e1002788. Epub 2012 Jul 12.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

View Article

Download full-text PDF

Source
https://dx.plos.org/10.1371/journal.ppat.1002788
Publisher Site
http://dx.doi.org/10.1371/journal.ppat.1002788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395615PMC
January 2013

Toll-like receptor 2 mediates fatal immunopathology in mice during treatment of secondary pneumococcal pneumonia following influenza.

J Infect Dis 2011 Nov 7;204(9):1358-66. Epub 2011 Sep 7.

Department of Infectious Diseases, St Jude Children's Research Hospital, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/infdis/jir522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218647PMC
November 2011

The p53-target gene puma drives neutrophil-mediated protection against lethal bacterial sepsis.

PLoS Pathog 2010 Dec 23;6(12):e1001240. Epub 2010 Dec 23.

Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America.

View Article

Download full-text PDF

Source
http://dx.plos.org/10.1371/journal.ppat.1001240
Publisher Site
http://dx.doi.org/10.1371/journal.ppat.1001240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009602PMC
December 2010

Pneumococcal pathogenesis: "innate invasion" yet organ-specific damage.

J Mol Med (Berl) 2010 Feb 17;88(2):103-7. Epub 2010 Feb 17.

Department of Infectious Diseases, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00109-009-0578-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864529PMC
February 2010

Early biofilm formation on microtiter plates is not correlated with the invasive disease potential of Streptococcus pneumoniae.

Microb Pathog 2010 Mar-Apr;48(3-4):124-30. Epub 2010 Jan 22.

Department of Microbiology and Immunology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S08824010100001
Publisher Site
http://dx.doi.org/10.1016/j.micpath.2010.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2834858PMC
May 2010

Statins protect against fulminant pneumococcal infection and cytolysin toxicity in a mouse model of sickle cell disease.

J Clin Invest 2010 Feb 19;120(2):627-35. Epub 2010 Jan 19.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-3678, USA.

View Article

Download full-text PDF

Source
http://www.jci.org/articles/view/39843
Publisher Site
http://dx.doi.org/10.1172/JCI39843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810080PMC
February 2010

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models.

J Clin Invest 2009 Jun 11;119(6):1638-46. Epub 2009 May 11.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI36759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689107PMC
June 2009

Role of the manganese efflux system mntE for signalling and pathogenesis in Streptococcus pneumoniae.

Mol Microbiol 2009 Apr 17;72(1):12-25. Epub 2009 Feb 17.

Department of Infectious Diseases, St Jude's Children's Research Hospital, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2958.2009.06638.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706702PMC
April 2009

Calcium efflux is essential for bacterial survival in the eukaryotic host.

Mol Microbiol 2008 Oct 29;70(2):435-44. Epub 2008 Aug 29.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2958.2008.06425.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577294PMC
October 2008

A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.

Am J Physiol Heart Circ Physiol 2008 Jun 25;294(6):H2775-84. Epub 2008 Apr 25.

Division of Critical Care Medicine, University of Tennessee Health Sciences Center, Memphis, Tennessee, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00269.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752689PMC
June 2008

Planning and implementation of an infection control training program for healthcare providers in Latin America.

Infect Control Hosp Epidemiol 2007 Dec 22;28(12):1328-33. Epub 2007 Oct 22.

International Outreach Program, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, 38105-2794, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/521655DOI Listing
December 2007

Assessment of molecular typing methods to determine invasiveness and to differentiate clones of Streptococcus pneumoniae.

Infect Genet Evol 2007 Dec 27;7(6):708-16. Epub 2007 Jul 27.

Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.meegid.2007.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2128056PMC
December 2007

Cellular damage in bacterial meningitis: an interplay of bacterial and host driven toxicity.

J Neuroimmunol 2007 Mar 8;184(1-2):45-52. Epub 2007 Jan 8.

Department of Cell Biology and Neurobiology, Charité - Universitaetsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jneuroim.2006.11.016DOI Listing
March 2007

Quinupristin-dalfopristin nonsusceptibility in pneumococci from sickle cell disease patients.

Antimicrob Agents Chemother 2007 Jan 23;51(1):386-9. Epub 2006 Oct 23.

Department of Infectious Diseases, St. Jude Children's Research Hospital, 332 North Lauderdale St., Memphis, TN 38105-2794, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.01016-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1797651PMC
January 2007

Interplay of pneumococcal hydrogen peroxide and host-derived nitric oxide.

Infect Immun 2006 Sep;74(9):5058-66

Department of Neurology, Charité-Universitaetsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/IAI.01932-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1594840PMC
September 2006

Cell wall-mediated neuronal damage in early sepsis.

Infect Immun 2006 Jul;74(7):3783-9

Infectious Diseases, St. Jude Children's Research Hospital, Mailstop 320 IRC 8057, 332 N. Lauderdale Rd., Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/IAI.00022-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489725PMC
July 2006

beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae.

Infect Immun 2005 Dec;73(12):7827-35

Department of Infectious Diseases, St. Jude Children's Research Hospital, Mailstop 320 IRC 8057, 332 N. Lauderdale Rd., Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/IAI.73.12.7827-7835.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1307033PMC
December 2005

Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae.

J Bacteriol 2005 Dec;187(23):8205-10

Departments of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JB.187.23.8205-8210.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291284PMC
December 2005

Preinfection systemic inflammatory markers and risk of hospitalization due to pneumonia.

Am J Respir Crit Care Med 2005 Dec 15;172(11):1440-6. Epub 2005 Sep 15.

Department of Critical Care Medicine, 3550 Terrace Street, Pittsburgh PA 15261, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1164/rccm.200506-888OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718438PMC
December 2005

Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance.

J Bacteriol 2004 Dec;186(24):8463-71

Department of Infectious Diseases, 332 N. Lauderdale St., Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JB.186.24.8463-8471.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC532416PMC
December 2004

Dual phases of apoptosis in pneumococcal meningitis.

J Infect Dis 2004 Dec 3;190(11):2039-46. Epub 2004 Nov 3.

Department of Infectious Diseases, St. Jude Children's Research Hospital, 332 N. Lauderdale Road, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/425520DOI Listing
December 2004

Tissue-specific contributions of pneumococcal virulence factors to pathogenesis.

J Infect Dis 2004 Nov 21;190(9):1661-9. Epub 2004 Sep 21.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/424596DOI Listing
November 2004

Microarray analysis of pneumococcal gene expression during invasive disease.

Infect Immun 2004 Oct;72(10):5582-96

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/IAI.72.10.5582-5596.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC517545PMC
October 2004

Tolerance to vancomycin in pneumococci: detection with a molecular marker and assessment of clinical impact.

J Infect Dis 2004 Oct 9;190(8):1481-7. Epub 2004 Sep 9.

Department of Infectious Diseases , St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1086/424467DOI Listing
October 2004

Bacterial inhibition of phosphatidylcholine synthesis triggers apoptosis in the brain.

J Exp Med 2004 Jul;200(1):99-106

Department of Infectious Diseases, St. Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20032100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2213312PMC
July 2004

Serum immunoglobulin G response to candidate vaccine antigens during experimental human pneumococcal colonization.

Infect Immun 2003 Oct;71(10):5724-32

Department of Microbiology and Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC201056PMC
http://dx.doi.org/10.1128/iai.71.10.5724-5732.2003DOI Listing
October 2003

Recognition of pneumococcal peptidoglycan: an expanded, pivotal role for LPS binding protein.

Immunity 2003 Aug;19(2):269-79

Department of Neurology, Universitaetsklinikum Charité, Humboldt University, 10117 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s1074-7613(03)00205-xDOI Listing
August 2003

Innate sensors for Gram-positive bacteria.

Curr Opin Immunol 2003 Aug;15(4):408-15

Dept of Neurology, Humboldt University, Charite Hospital, Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0952-7915(03)00078-5DOI Listing
August 2003

Molecular analysis of antibiotic tolerance in pneumococci.

Int J Med Microbiol 2002 Jul;292(2):75-9

Department of Infectious Diseases, St. Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1078/1438-4221-00193DOI Listing
July 2002

Pneumococcal pneumolysin and H(2)O(2) mediate brain cell apoptosis during meningitis.

J Clin Invest 2002 Jan;109(1):19-27

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI12035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC150815PMC
January 2002