Elaine Holmes

Elaine Holmes

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Elaine Holmes

Elaine Holmes

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Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent infection.

Authors:
Benjamin H Mullish Julie A K McDonald Alexandros Pechlivanis Jessica R Allegretti Dina Kao Grace F Barker Diya Kapila Elaine O Petrof Susan A Joyce Cormac G M Gahan Izabela Glegola-Madejska Horace R T Williams Elaine Holmes Thomas B Clarke Mark R Thursz Julian R Marchesi

Gut 2019 10 11;68(10):1791-1800. Epub 2019 Feb 11.

Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/gutjnl-2018-317842DOI Listing
October 2019

Spot and Cumulative Urine Samples Are Suitable Replacements for 24-Hour Urine Collections for Objective Measures of Dietary Exposure in Adults Using Metabolite Biomarkers.

Authors:
Thomas Wilson Isabel Garcia-Perez Joram M Posma Amanda J Lloyd Edward S Chambers Kathleen Tailliart Hassan Zubair Manfred Beckmann John C Mathers Elaine Holmes Gary Frost John Draper

J Nutr 2019 Oct;149(10):1692-1700

Institute of Biological, Environmental, and Rural Sciences, Aberystwyth University, Aberystwyth, United Kingdom.

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http://dx.doi.org/10.1093/jn/nxz138DOI Listing
October 2019

Metabolic Phenotyping in Venous Disease: The Need for Standardization.

Authors:
Sarah Onida Matthew K H Tan Marina Kafeza Richmond T Bergner Joseph Shalhoub Elaine Holmes Alun H Davies

J Proteome Res 2019 Oct 16. Epub 2019 Oct 16.

Academic Section of Vascular Surgery, Department of Surgery and Cancer , Imperial College London , Floor 4 East, Charing Cross Hospital, Fulham Palace Road , London W6 8RF , U.K.

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http://dx.doi.org/10.1021/acs.jproteome.9b00460DOI Listing
October 2019

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease.

Authors:
Ioanna Tzoulaki Raphaële Castagné Claire L Boulangé Ibrahim Karaman Elena Chekmeneva Evangelos Evangelou Timothy M D Ebbels Manuja R Kaluarachchi Marc Chadeau-Hyam David Mosen Abbas Dehghan Alireza Moayyeri Diana L Santos Ferreira Xiuqing Guo Jerome I Rotter Kent D Taylor Maryam Kavousi Paul S de Vries Benjamin Lehne Marie Loh Albert Hofman Jeremy K Nicholson John Chambers Christian Gieger Elaine Holmes Russell Tracy Jaspal Kooner Philip Greenland Oscar H Franco David Herrington John C Lindon Paul Elliott

Eur Heart J 2019 Sep;40(34):2883-2896

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London, UK.

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http://dx.doi.org/10.1093/eurheartj/ehz235DOI Listing
September 2019

Multi-Compartment Profiling of Bacterial and Host Metabolites Identifies Intestinal Dysbiosis and Its Functional Consequences in the Critically Ill Child.

Authors:
Anisha Wijeyesekera Josef Wagner Marcus De Goffau Sarah Thurston Adilson Rodrigues Sabino Sara Zaher Deborah White Jenna Ridout Mark J Peters Padmanabhan Ramnarayan Ricardo G Branco M Estee Torok Frederic Valla Rosan Meyer Nigel Klein Gary Frost Julian Parkhill Elaine Holmes Nazima Pathan

Crit Care Med 2019 Sep;47(9):e727-e734

Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1097/CCM.0000000000003841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699985PMC
September 2019

A Unified Conceptual Framework for Metabolic Phenotyping in Diagnosis and Prognosis.

Authors:
Jeremy R Everett Elaine Holmes Kirill A Veselkov John C Lindon Jeremy K Nicholson

Trends Pharmacol Sci 2019 Sep 9. Epub 2019 Sep 9.

Division of Computational and Systems Medicine and Medical Research Council (MRC) National Institute for Health Research (NIHR) National Phenome Centre, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London SW7 2AZ, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tips.2019.08.004DOI Listing
September 2019

Association of Untargeted Urinary Metabolomics and Lung Cancer Risk Among Never-Smoking Women in China.

Authors:
Wei Jie Seow Xiao-Ou Shu Jeremy K Nicholson Elaine Holmes Douglas I Walker Wei Hu Qiuyin Cai Yu-Tang Gao Yong-Bing Xiang Steven C Moore Bryan A Bassig Jason Y Y Wong Jinming Zhang Bu-Tian Ji Claire L Boulangé Manuja Kaluarachchi Anisha Wijeyesekera Wei Zheng Paul Elliott Nathaniel Rothman Qing Lan

JAMA Netw Open 2019 Sep 4;2(9):e1911970. Epub 2019 Sep 4.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland.

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http://dx.doi.org/10.1001/jamanetworkopen.2019.11970DOI Listing
September 2019

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial.

Authors:
Edward S Chambers Claire S Byrne Douglas J Morrison Kevin G Murphy Tom Preston Catriona Tedford Isabel Garcia-Perez Sofia Fountana Jose Ivan Serrano-Contreras Elaine Holmes Catherine J Reynolds Jordie F Roberts Rosemary J Boyton Daniel M Altmann Julie A K McDonald Julian R Marchesi Arne N Akbar Natalie E Riddell Gareth A Wallis Gary S Frost

Gut 2019 08 10;68(8):1430-1438. Epub 2019 Apr 10.

Section for Nutrition Research, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/gutjnl-2019-318424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691855PMC
August 2019

Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis.

Authors:
Caroline Ovadia Alvaro Perdones-Montero Konstantina Spagou Ann Smith Magali H Sarafian Maria Gomez-Romero Elena Bellafante Louise C D Clarke Fouzia Sadiq Vanya Nikolova Alice Mitchell Peter H Dixon Natalie Santa-Pinter Annika Wahlström Shadi Abu-Hayyeh Julian R F Walters Hanns-Ulrich Marschall Elaine Holmes Julian R Marchesi Catherine Williamson

Hepatology 2019 Jul 21;70(1):276-293. Epub 2019 May 21.

Division of Women and Children's Health, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/hep.30661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619257PMC
July 2019

The gut microbiota influences skeletal muscle mass and function in mice.

Authors:
Shawon Lahiri Hyejin Kim Isabel Garcia-Perez Musarrat Maisha Reza Katherine A Martin Parag Kundu Laura M Cox Joel Selkrig Joram M Posma Hongbo Zhang Parasuraman Padmanabhan Catherine Moret Balázs Gulyás Martin J Blaser Johan Auwerx Elaine Holmes Jeremy Nicholson Walter Wahli Sven Pettersson

Sci Transl Med 2019 Jul;11(502)

Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1126/scitranslmed.aan5662DOI Listing
July 2019

Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus.

Authors:
Vinod S Hegade Alexandros Pechlivanis Julie A K McDonald Douglas Rees Margaret Corrigan Gideon M Hirschfield Simon D Taylor-Robinson Elaine Holmes Julian R Marchesi Stuart Kendrick David E Jones

Liver Int 2019 May 25;39(5):967-975. Epub 2019 Feb 25.

Institute of Cellular Medicine and NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, UK.

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http://dx.doi.org/10.1111/liv.14069DOI Listing
May 2019

Obesity and Cage Environment Modulate Metabolism in the Zucker Rat: A Multiple Biological Matrix Approach to Characterizing Metabolic Phenomena.

Authors:
Hannah J Lees Jonathan R Swann Simon Poucher Elaine Holmes Ian D Wilson Jeremy K Nicholson

J Proteome Res 2019 May 18;18(5):2160-2174. Epub 2019 Apr 18.

Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine , Imperial College London , London , SW7 2AZ , United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.9b00040DOI Listing
May 2019

Characterization of the urinary metabolic profile of cholangiocarcinoma in a United Kingdom population.

Authors:
Munirah Alsaleh Thomas A Barbera Helen L Reeves Matthew E Cramp Stephen Ryder Hani Gabra Kathryn Nash Yi-Liang Shen Elaine Holmes Roger Williams Simon D Taylor-Robinson

Hepat Med 2019 3;11:47-67. Epub 2019 May 3.

Division of Surgery and Cancer, Imperial College London, London.

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https://www.dovepress.com/characterization-of-the-urinary-me
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http://dx.doi.org/10.2147/HMER.S193996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507078PMC
May 2019

Bariatric Surgery Modulates Urinary Levels of MicroRNAs Involved in the Regulation of Renal Function.

Authors:
Abdullah Alkandari Hutan Ashrafian Thozhukat Sathyapalan Ara Darzi Elaine Holmes Thanos Athanasiou Stephen L Atkin Nigel J Gooderham

Front Endocrinol (Lausanne) 2019 21;10:319. Epub 2019 May 21.

Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.3389/fendo.2019.00319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536704PMC
May 2019

Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts.

Authors:
Luke Whiley Leanne C Nye Isobelle Grant Nick Andreas Katie E Chappell Magali H Sarafian Ravi Misra Robert S Plumb Matthew R Lewis Jeremy K Nicholson Elaine Holmes Jonathan R Swann Ian D Wilson

Anal Chem 2019 Apr 25;91(8):5207-5216. Epub 2019 Mar 25.

Division of Integrative Systems and Digestive Medicine, Department of Surgery and Cancer , Imperial College London , Sir Alexander Fleming Building, South Kensington Campus , London SW7 2AZ , United Kingdom.

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http://dx.doi.org/10.1021/acs.analchem.8b05884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503468PMC
April 2019

Effects of Inulin Propionate Ester Incorporated into Palatable Food Products on Appetite and Resting Energy Expenditure: A Randomised Crossover Study.

Authors:
Claire S Byrne Edward S Chambers Tom Preston Catriona Tedford Jerusa Brignardello Isabel Garcia-Perez Elaine Holmes Gareth A Wallis Douglas J Morrison Gary S Frost

Nutrients 2019 Apr 16;11(4). Epub 2019 Apr 16.

Section for Nutrition Research, Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.

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https://www.mdpi.com/2072-6643/11/4/861
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http://dx.doi.org/10.3390/nu11040861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520886PMC
April 2019

NMR and MS urinary metabolic phenotyping in kidney diseases is fit-for-purpose in the presence of a protease inhibitor.

Authors:
Claire L Boulangé Ilse M Rood Joram M Posma John C Lindon Elaine Holmes Jack F M Wetzels Jeroen K J Deegens Manuja R Kaluarachchi

Mol Omics 2019 02;15(1):39-49

Metabometrix Ltd, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, UK.

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http://dx.doi.org/10.1039/c8mo00190aDOI Listing
February 2019

The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans.

Authors:
Chioma Izzi-Engbeaya Alexander N Comninos Sophie A Clarke Anne Jomard Lisa Yang Sophie Jones Ali Abbara Shakunthala Narayanaswamy Pei Chia Eng Deborah Papadopoulou Julia K Prague Paul Bech Ian F Godsland Paul Bassett Caroline Sands Stephane Camuzeaux Maria Gomez-Romero Jake T M Pearce Matthew R Lewis Elaine Holmes Jeremy K Nicholson Tricia Tan Risheka Ratnasabapathy Ming Hu Gaelle Carrat Lorenzo Piemonti Marco Bugliani Piero Marchetti Paul R Johnson Stephen J Hughes A M James Shapiro Guy A Rutter Waljit S Dhillo

Diabetes Obes Metab 2018 12 16;20(12):2800-2810. Epub 2018 Aug 16.

Section of Endocrinology and Investigative Medicine, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, UK.

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http://doi.wiley.com/10.1111/dom.13460
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http://dx.doi.org/10.1111/dom.13460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282711PMC
December 2018

The metabolic fate and effects of 2-Bromophenol in male Sprague-Dawley rats.

Authors:
Kyrillos N Adesina-Georgiadis Nicola Gray Robert S Plumb David F Thompson Elaine Holmes Jeremy K Nicholson Ian D Wilson

Xenobiotica 2018 Dec 17:1-8. Epub 2018 Dec 17.

a Department of Surgery and Cancer Faculty of Medicine , Imperial College London, South Kensington Campus , London , United Kingdom.

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https://www.tandfonline.com/doi/full/10.1080/00498254.2018.1
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http://dx.doi.org/10.1080/00498254.2018.1559376DOI Listing
December 2018

Inhibiting Growth of Clostridioides difficile by Restoring Valerate, Produced by the Intestinal Microbiota.

Authors:
Julie A K McDonald Benjamin H Mullish Alexandros Pechlivanis Zhigang Liu Jerusa Brignardello Dina Kao Elaine Holmes Jia V Li Thomas B Clarke Mark R Thursz Julian R Marchesi

Gastroenterology 2018 11 17;155(5):1495-1507.e15. Epub 2018 Jul 17.

Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, United Kingdom; School of Biosciences, Cardiff University, Cardiff, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183477
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http://dx.doi.org/10.1053/j.gastro.2018.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347096PMC
November 2018

Metabolic phenotype of skeletal muscle in early critical illness.

Authors:
Zudin A Puthucheary Ronan Astin Mark J W Mcphail Saima Saeed Yasmin Pasha Danielle E Bear Despina Constantin Cristiana Velloso Sean Manning Lori Calvert Mervyn Singer Rachel L Batterham Maria Gomez-Romero Elaine Holmes Michael C Steiner Philip J Atherton Paul Greenhaff Lindsay M Edwards Kenneth Smith Stephen D Harridge Nicholas Hart Hugh E Montgomery

Thorax 2018 10 6;73(10):926-935. Epub 2018 Jul 6.

Institute for Sport, Exercise and Health, University College London, London, UK.

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http://dx.doi.org/10.1136/thoraxjnl-2017-211073DOI Listing
October 2018

Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Authors:
Lesley Hoyles José-Manuel Fernández-Real Massimo Federici Matteo Serino James Abbott Julie Charpentier Christophe Heymes Jèssica Latorre Luque Elodie Anthony Richard H Barton Julien Chilloux Antonis Myridakis Laura Martinez-Gili José Maria Moreno-Navarrete Fadila Benhamed Vincent Azalbert Vincent Blasco-Baque Josep Puig Gemma Xifra Wifredo Ricart Christopher Tomlinson Mark Woodbridge Marina Cardellini Francesca Davato Iris Cardolini Ottavia Porzio Paolo Gentileschi Frédéric Lopez Fabienne Foufelle Sarah A Butcher Elaine Holmes Jeremy K Nicholson Catherine Postic Rémy Burcelin Marc-Emmanuel Dumas

Nat Med 2018 Oct;24(10):1628

Division of Integrative Systems Medicine and Digestive Diseases, Department of Surgery and Cancer, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/s41591-018-0169-5DOI Listing
October 2018

Effects of Vancomycin and Ciprofloxacin on the NMRI Mouse Metabolism.

Authors:
Zhigang Liu Bing Xia Jasmina Saric Jürg Utzinger Elaine Holmes Jennifer Keiser Jia V Li

J Proteome Res 2018 10 20;17(10):3565-3573. Epub 2018 Sep 20.

Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Faculty of Medicine , Imperial College London , South Kensington Campus , London SW7 2AZ , United Kingdom.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.8b00583
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http://dx.doi.org/10.1021/acs.jproteome.8b00583DOI Listing
October 2018

Ultra-Performance Liquid Chromatography-High-Resolution Mass Spectrometry and Direct Infusion-High-Resolution Mass Spectrometry for Combined Exploratory and Targeted Metabolic Profiling of Human Urine.

Authors:
Elena Chekmeneva Gonçalo Dos Santos Correia María Gómez-Romero Jeremiah Stamler Queenie Chan Paul Elliott Jeremy K Nicholson Elaine Holmes

J Proteome Res 2018 10 19;17(10):3492-3502. Epub 2018 Sep 19.

Division of Integrative Systems and Digestive Medicine, Department of Surgery and Cancer , Imperial College London , Sir Alexander Fleming Building, South Kensington Campus , London SW7 2AZ , United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.8b00413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6184476PMC
October 2018

Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by H NMR Spectroscopy in a Multilaboratory Trial.

Authors:
Beatriz Jiménez Elaine Holmes Clement Heude Rose F Tolson Nikita Harvey Samantha L Lodge Andrew J Chetwynd Claire Cannet Fang Fang Jake T M Pearce Matthew R Lewis Mark R Viant John C Lindon Manfred Spraul Hartmut Schäfer Jeremy K Nicholson

Anal Chem 2018 10 27;90(20):11962-11971. Epub 2018 Sep 27.

The Imperial Clinical Phenotyping Centre, Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer , QEQM Building, Saint Mary's Hospital , London W2 1NY , United Kingdom.

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http://dx.doi.org/10.1021/acs.analchem.8b02412DOI Listing
October 2018

Profiling inflammatory markers in patients with pneumonia on intensive care.

Authors:
David B Antcliffe Arnaud M Wolfer Kieran P O'Dea Masao Takata Elaine Holmes Anthony C Gordon

Sci Rep 2018 10 3;8(1):14736. Epub 2018 Oct 3.

Section of Anaesthetics, Pain Medicine and Intensive Care, Imperial College London, London, UK.

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http://www.nature.com/articles/s41598-018-32938-6
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http://dx.doi.org/10.1038/s41598-018-32938-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170441PMC
October 2018

The effect of L-rhamnose on intestinal transit time, short chain fatty acids and appetite regulation: a pilot human study using combined CO/H breath tests.

Authors:
Claire S Byrne Tom Preston Jerusa Brignardello Isabel Garcia-Perez Elaine Holmes Gary S Frost Douglas J Morrison

J Breath Res 2018 08 6;12(4):046006. Epub 2018 Aug 6.

Nutrition and Dietetic Research Group, Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, United Kingdom.

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http://stacks.iop.org/1752-7163/12/i=4/a=046006?key=crossref
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http://dx.doi.org/10.1088/1752-7163/aad3f1DOI Listing
August 2018

odifying ntestinal Integrity and icro iome in Severe Malnutrition with gume-Based Feeds (MIMBLE 2.0): protocol for a phase II refined feed and intervention trial.

Authors:
Kevin Walsh Nuala Calder Peter Olupot-Olupot Tonny Ssenyondo William Okiror Charles Bernard Okalebo Rita Muhindo Ayub Mpoya Elaine Holmes Julian Marchesi Gael Delamare de la Villenaise de Chenevarin Gary Frost Kathryn Maitland

Wellcome Open Res 2018 2;3:95. Epub 2018 Aug 2.

Department of Paediatrics, Imperial College, London, W2 1PG, UK.

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https://wellcomeopenresearch.org/articles/3-95/v1
Publisher Site
http://dx.doi.org/10.12688/wellcomeopenres.14706.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171552PMC
August 2018

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women.

Authors:
Lesley Hoyles José-Manuel Fernández-Real Massimo Federici Matteo Serino James Abbott Julie Charpentier Christophe Heymes Jèssica Latorre Luque Elodie Anthony Richard H Barton Julien Chilloux Antonis Myridakis Laura Martinez-Gili José Maria Moreno-Navarrete Fadila Benhamed Vincent Azalbert Vincent Blasco-Baque Josep Puig Gemma Xifra Wifredo Ricart Christopher Tomlinson Mark Woodbridge Marina Cardellini Francesca Davato Iris Cardolini Ottavia Porzio Paolo Gentileschi Frédéric Lopez Fabienne Foufelle Sarah A Butcher Elaine Holmes Jeremy K Nicholson Catherine Postic Rémy Burcelin Marc-Emmanuel Dumas

Nat Med 2018 07 25;24(7):1070-1080. Epub 2018 Jun 25.

Division of Integrative Systems Medicine and Digestive Diseases, Department of Surgery and Cancer, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/s41591-018-0061-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6140997PMC
July 2018

The C6H6 NMR repository: An integral solution to control the flow of your data from the magnet to the public.

Authors:
Luc Patiny Michaël Zasso Daniel Kostro Andrés Bernal Andrés M Castillo Alejandro Bolaños Miguel A Asencio Norman Pellet Matthew Todd Nils Schloerer Stefan Kuhn Elaine Holmes Sacha Javor Julien Wist

Magn Reson Chem 2018 06 3;56(6):520-528. Epub 2017 Nov 3.

Chemistry Department, Universidad del Valle, Cali, Valle, Colombia.

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http://doi.wiley.com/10.1002/mrc.4669
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http://dx.doi.org/10.1002/mrc.4669DOI Listing
June 2018

Deep Vein Thrombosis Exhibits Characteristic Serum and Vein Wall Metabolic Phenotypes in the Inferior Vena Cava Ligation Mouse Model.

Authors:
Yeji Sung Konstantina Spagou Marina Kafeza Michael Kyriakides Brahman Dharmarajah Joseph Shalhoub Jose A Diaz Thomas W Wakefield Elaine Holmes Alun H Davies

Eur J Vasc Endovasc Surg 2018 05 8;55(5):703-713. Epub 2018 Mar 8.

Academic Section of Vascular Surgery, Department of Surgery and Cancer, Imperial College London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ejvs.2018.01.027DOI Listing
May 2018

Improved physiology and metabolic flux after Roux-en-Y gastric bypass is associated with temporal changes in the circulating microRNAome: a longitudinal study in humans.

Authors:
Abdullah Alkandari Hutan Ashrafian Thozhukat Sathyapalan Peter Sedman Ara Darzi Elaine Holmes Thanos Athanasiou Stephen L Atkin Nigel J Gooderham

BMC Obes 2018 31;5:20. Epub 2018 May 31.

1Department of Surgery and Cancer, Imperial College London, London, UK.

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http://dx.doi.org/10.1186/s40608-018-0199-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984421PMC
May 2018

The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level.

Authors:
Wiley Barton Nicholas C Penney Owen Cronin Isabel Garcia-Perez Michael G Molloy Elaine Holmes Fergus Shanahan Paul D Cotter Orla O'Sullivan

Gut 2018 04 30;67(4):625-633. Epub 2017 Mar 30.

Alimentary Pharmabiotic Centre Microbiome Institute, University College Cork, National University of Ireland, Cork, Ireland.

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http://dx.doi.org/10.1136/gutjnl-2016-313627DOI Listing
April 2018

Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data.

Authors:
Joram M Posma Isabel Garcia-Perez Timothy M D Ebbels John C Lindon Jeremiah Stamler Paul Elliott Elaine Holmes Jeremy K Nicholson

J Proteome Res 2018 04 27;17(4):1586-1595. Epub 2018 Feb 27.

Department of Preventive Medicine, Feinberg School of Medicine , Northwestern University , Chicago , Illinois 60611 , United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891819PMC
April 2018

A Prospective Metagenomic and Metabolomic Analysis of the Impact of Exercise and/or Whey Protein Supplementation on the Gut Microbiome of Sedentary Adults.

Authors:
Owen Cronin Wiley Barton Peter Skuse Nicholas C Penney Isabel Garcia-Perez Eileen F Murphy Trevor Woods Helena Nugent Aine Fanning Silvia Melgar Eanna C Falvey Elaine Holmes Paul D Cotter Orla O'Sullivan Michael G Molloy Fergus Shanahan

mSystems 2018 May-Jun;3(3). Epub 2018 Apr 24.

APC Microbiome Ireland, National University of Ireland, Cork, Ireland.

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http://dx.doi.org/10.1128/mSystems.00044-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915698PMC
April 2018

Characterization of metabolic responses to healthy diets and association with blood pressure: application to the Optimal Macronutrient Intake Trial for Heart Health (OmniHeart), a randomized controlled study.

Authors:
Ruey Leng Loo Xin Zou Lawrence J Appel Jeremy K Nicholson Elaine Holmes

Am J Clin Nutr 2018 03;107(3):323-334

Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1093/ajcn/nqx072DOI Listing
March 2018

Rifaximin in non-alcoholic steatohepatitis: An open-label pilot study.

Authors:
Jeremy F L Cobbold Stephen Atkinson Julian R Marchesi Ann Smith Sann N Wai Julie Stove Fariba Shojaee-Moradie Nicola Jackson A Margot Umpleby Julie Fitzpatrick E Louise Thomas Jimmy D Bell Elaine Holmes Simon D Taylor-Robinson Robert D Goldin Michael S Yee Quentin M Anstee Mark R Thursz

Hepatol Res 2018 Jan 31;48(1):69-77. Epub 2017 May 31.

Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1111/hepr.12904DOI Listing
January 2018

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin.

Authors:
Richard G Brown Julian R Marchesi Yun S Lee Ann Smith Benjamin Lehne Lindsay M Kindinger Vasso Terzidou Elaine Holmes Jeremy K Nicholson Phillip R Bennett David A MacIntyre

BMC Med 2018 01 24;16(1). Epub 2018 Jan 24.

Imperial College Parturition Research Group, Division of the Institute of Reproductive and Developmental Biology, Imperial College London, London, W12 0NN, UK.

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http://dx.doi.org/10.1186/s12916-017-0999-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5782380PMC
January 2018

Metabolic Profiling of Central Nervous System Disease in Trypanosoma brucei rhodesiense Infection.

Authors:
Sabrina D Lamour Vincent P Alibu Elaine Holmes Jeremy M Sternberg

J Infect Dis 2017 12;216(10):1273-1280

Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1093/infdis/jix466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5853393PMC
December 2017

Urinary Metabolic Phenotyping of Women with Lower Urinary Tract Symptoms.

Authors:
Rhiannon Bray Stefano Cacciatore Beatriz Jiménez Rufus Cartwright Alex Digesu Ruwan Fernando Elaine Holmes Jeremy K Nicholson Phillip R Bennett David A MacIntyre Vik Khullar

J Proteome Res 2017 11 4;16(11):4208-4216. Epub 2017 Oct 4.

Department of Urogynaecology, St. Mary's Hospital, Imperial College Healthcare NHS Trust , London W2 1NY, U.K.

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http://dx.doi.org/10.1021/acs.jproteome.7b00568DOI Listing
November 2017

Metabolomics as a tool to identify biomarkers to predict and improve outcomes in reproductive medicine: a systematic review.

Authors:
Timothy Bracewell-Milnes Srdjan Saso Hossam Abdalla Dimitrios Nikolau Julian Norman-Taylor Mark Johnson Elaine Holmes Meen-Yau Thum

Hum Reprod Update 2017 11;23(6):723-736

The Lister Fertility Clinic, Chelsea Bridge Road, London, UK.

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http://dx.doi.org/10.1093/humupd/dmx023DOI Listing
November 2017

Early preterm nutrition and the urinary metabolome in young adult life: follow-up of a randomised controlled trial.

Authors:
James R C Parkinson Anisha D Wijeyesekera Matthew J Hyde Atul Singhal Alan Lucas Elaine Holmes Neena Modi

BMJ Paediatr Open 2017 1;1(1):e000192. Epub 2017 Nov 1.

Section of Neonatal Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/bmjpo-2017-000192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862206PMC
November 2017

Ethnicity and skin autofluorescence-based risk-engines for cardiovascular disease and diabetes mellitus.

Authors:
Muhammad Saeed Ahmad Torben Kimhofer Sultan Ahmad Mohammed Nabil AlAma Hala Hisham Mosli Salwa Ibrahim Hindawi Dennis O Mook-Kanamori Katarína Šebeková Zoheir Abdullah Damanhouri Elaine Holmes

PLoS One 2017 20;12(9):e0185175. Epub 2017 Sep 20.

Drug Metabolism Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185175PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607192PMC
October 2017

Lessons from Metabonomics on the Neurobiology of Stroke.

Authors:
Mahim I Qureshi Panagiotis A Vorkas Alexander P Coupland I Harri Jenkins Elaine Holmes Alun H Davies

Neuroscientist 2017 08 24;23(4):374-382. Epub 2016 Oct 24.

1 Section of Vascular Surgery, Imperial College London, Charing Cross Hospital, London, UK.

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http://dx.doi.org/10.1177/1073858416673327DOI Listing
August 2017

Application of Metabolic Profiling to Abdominal Aortic Aneurysm Research.

Authors:
Mahim I Qureshi Michele Greco Panagiotis A Vorkas Elaine Holmes Alun H Davies

J Proteome Res 2017 07 19;16(7):2325-2332. Epub 2017 Jun 19.

Section of Vascular Surgery, Imperial College London , 4 North, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.6b00894DOI Listing
July 2017

Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment.

Authors:
Marie C Lewis Claire A Merrifield Bernard Berger Olivier Cloarec Swantje Duncker Annick Mercenier Jeremy K Nicholson Elaine Holmes Mick Bailey

Sci Rep 2017 07 13;7(1):5310. Epub 2017 Jul 13.

Infection and Immunity, Department of Clinical Veterinary Science, University of Bristol, Langford House, Langford, North Somerset, BS40 5DU, UK.

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http://dx.doi.org/10.1038/s41598-017-05689-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509696PMC
July 2017

A comprehensive characterisation of the metabolic profile of varicose veins; implications in elaborating plausible cellular pathways for disease pathogenesis.

Authors:
Muzaffar A Anwar Kyrillos N Adesina-Georgiadis K Spagou P A Vorkas J V Li Joseph Shalhoub Elaine Holmes Alun H Davies

Sci Rep 2017 06 7;7(1):2989. Epub 2017 Jun 7.

Academic Section of Vascular Surgery, Imperial College, London, UK.

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http://dx.doi.org/10.1038/s41598-017-02529-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5462754PMC
June 2017

The Plasma and Serum Metabotyping of Hepatocellular Carcinoma in a Nigerian and Egyptian Cohort using Proton Nuclear Magnetic Resonance Spectroscopy.

Authors:
Mohamed I F Shariff Jin Un Kim Nimzing G Ladep Asmaa I Gomaa Mary M E Crossey Edith Okeke Edmund Banwat Imam Waked I Jane Cox Roger Williams Elaine Holmes Simon D Taylor-Robinson

J Clin Exp Hepatol 2017 Jun 15;7(2):83-92. Epub 2017 Mar 15.

Division of Digestive Health, Department of Surgery and Cancer, Imperial College London, St Mary's Campus, South Wharf Road, London W2 1NY, United Kingdom.

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http://dx.doi.org/10.1016/j.jceh.2017.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478965PMC
June 2017

Deep learning and 3D-DESI imaging reveal the hidden metabolic heterogeneity of cancer.

Authors:
Paolo Inglese James S McKenzie Anna Mroz James Kinross Kirill Veselkov Elaine Holmes Zoltan Takats Jeremy K Nicholson Robert C Glen

Chem Sci 2017 May 21;8(5):3500-3511. Epub 2017 Feb 21.

Department of Surgery and Cancer - Division of Computational and Systems Medicine , Imperial College London , London , UK . Email: ; Email: ; Email:

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http://xlink.rsc.org/?DOI=C6SC03738K
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http://dx.doi.org/10.1039/c6sc03738kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418631PMC
May 2017

Corrigendum: A new gender-specific model for skin autofluorescence risk stratification.

Authors:
Muhammad S Ahmad Zoheir A Damanhouri Torben Kimhofer Hala H Mosli Elaine Holmes

Sci Rep 2017 05 31;7:46832. Epub 2017 May 31.

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http://dx.doi.org/10.1038/srep46832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450875PMC
May 2017

Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: an overview.

Authors:
Queenie Chan Ruey Leng Loo Timothy M D Ebbels Linda Van Horn Martha L Daviglus Jeremiah Stamler Jeremy K Nicholson Elaine Holmes Paul Elliott

Hypertens Res 2017 Apr 22;40(4):336-345. Epub 2016 Dec 22.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/hr.2016.164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278595PMC
April 2017

Optimization and Application of Direct Infusion Nanoelectrospray HRMS Method for Large-Scale Urinary Metabolic Phenotyping in Molecular Epidemiology.

Authors:
Elena Chekmeneva Gonçalo Dos Santos Correia Queenie Chan Anisha Wijeyesekera Adrienne Tin Jeffery Hunter Young Paul Elliott Jeremy K Nicholson Elaine Holmes

J Proteome Res 2017 04 14;16(4):1646-1658. Epub 2017 Mar 14.

Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London , South Kensington, London SW7 2AZ, United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.6b01003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5387673PMC
April 2017

Metabolic Profiling in Patients with Pneumonia on Intensive Care.

Authors:
David Antcliffe Beatriz Jiménez Kirill Veselkov Elaine Holmes Anthony C Gordon

EBioMedicine 2017 Apr 29;18:244-253. Epub 2017 Mar 29.

Section of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.03.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405179PMC
April 2017

Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery.

Authors:
Arnaud M Wolfer Alasdair J Scott Claudia Rueb Mathieu Gaudin Ara Darzi Jeremy K Nicholson Elaine Holmes James M Kinross

J Transl Med 2017 04 26;15(1):83. Epub 2017 Apr 26.

Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.

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http://dx.doi.org/10.1186/s12967-017-1171-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405545PMC
April 2017

Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial.

Authors:
Isabel Garcia-Perez Joram M Posma Rachel Gibson Edward S Chambers Tue H Hansen Henrik Vestergaard Torben Hansen Manfred Beckmann Oluf Pedersen Paul Elliott Jeremiah Stamler Jeremy K Nicholson John Draper John C Mathers Elaine Holmes Gary Frost

Lancet Diabetes Endocrinol 2017 03 13;5(3):184-195. Epub 2017 Jan 13.

Nutrition and Dietetic Research Group, Division of Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(16)30419-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357736PMC
March 2017

Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers.

Authors:
Joram M Posma Isabel Garcia-Perez James C Heaton Paula Burdisso John C Mathers John Draper Matt Lewis John C Lindon Gary Frost Elaine Holmes Jeremy K Nicholson

Anal Chem 2017 03 10;89(6):3300-3309. Epub 2017 Mar 10.

Section of Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, South Kensington Campus, Imperial College London , London SW7 2AZ, United Kingdom.

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http://dx.doi.org/10.1021/acs.analchem.6b03324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5379249PMC
March 2017

Metabolic Phenotype of Obesity in a Saudi Population.

Authors:
Muhammad Saeed Ahmad Munirah Alsaleh Torben Kimhofer Sultan Ahmad Wisam Jamal Siraj Omar Wali Jeremy Kirk Nicholson Zoheir Abdullah Damanhouri Elaine Holmes

J Proteome Res 2017 02 20;16(2):635-644. Epub 2017 Jan 20.

Biomolecular Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London , South Kensington, London SW7 2AZ, United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.6b00710DOI Listing
February 2017

Medical Swab Analysis Using Desorption Electrospray Ionization Mass Spectrometry: A Noninvasive Approach for Mucosal Diagnostics.

Authors:
Pamela Pruski David A MacIntyre Holly V Lewis Paolo Inglese Gonçalo D S Correia Trevor T Hansel Phillip R Bennett Elaine Holmes Zoltan Takats

Anal Chem 2017 02 11;89(3):1540-1550. Epub 2017 Jan 11.

Computational and Systems Medicine, Imperial College London , South Kensington Campus, London, SW7 2AZ, United Kingdom.

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http://dx.doi.org/10.1021/acs.analchem.6b03405DOI Listing
February 2017

The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk.

Authors:
Lindsay M Kindinger Phillip R Bennett Yun S Lee Julian R Marchesi Ann Smith Stefano Cacciatore Elaine Holmes Jeremy K Nicholson T G Teoh David A MacIntyre

Microbiome 2017 01 19;5(1). Epub 2017 Jan 19.

Imperial College Parturition Research Group, Division of the Institute of Reproductive and Developmental Biology, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Hammersmith Campus, London, W12 0NN, UK.

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http://dx.doi.org/10.1186/s40168-016-0223-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5244550PMC
January 2017

Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer.

Authors:
Michael Kyriakides Lea Maitre Brendan D Stamper Isaac Mohar Terrance J Kavanagh John Foster Ian D Wilson Elaine Holmes Sidney D Nelson Muireann Coen

Arch Toxicol 2016 Dec 9;90(12):3073-3085. Epub 2016 Jan 9.

Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK.

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http://dx.doi.org/10.1007/s00204-015-1655-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104807PMC
December 2016

New technologies - new insights into the pathogenesis of hepatic encephalopathy.

Authors:
Luisa Baker Bernard Lanz Fausto Andreola Javier Ampuero Anisha Wijeyesekera Elaine Holmes Nicolaas Deutz

Metab Brain Dis 2016 12 30;31(6):1259-1267. Epub 2016 Sep 30.

Department of Health & Kinesiology, Texas A&M University, College Station, TX, USA.

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http://dx.doi.org/10.1007/s11011-016-9906-yDOI Listing
December 2016

Correction to 2-Furoylglycine as a Candidate Biomarker of Coffee Consumption.

Authors:
Silke S Heinzmann Elaine Holmes Sunil Kochhar Jeremy K Nicholson Philippe Schmitt-Kopplin

J Agric Food Chem 2016 Nov 11;64(46):8958. Epub 2016 Nov 11.

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http://dx.doi.org/10.1021/acs.jafc.6b04833DOI Listing
November 2016

Development of a Pipeline for Exploratory Metabolic Profiling of Infant Urine.

Authors:
Frances Jackson Nancy Georgakopoulou Manuja Kaluarachchi Michael Kyriakides Nicholas Andreas Natalia Przysiezna Matthew J Hyde Neena Modi Jeremy K Nicholson Anisha Wijeyesekera Elaine Holmes

J Proteome Res 2016 09 23;15(9):3432-40. Epub 2016 Aug 23.

Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London , South Kensington Campus, London SW7 2AZ, United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.6b00234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716460PMC
September 2016

Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping.

Authors:
Matthew R Lewis Jake T M Pearce Konstantina Spagou Martin Green Anthony C Dona Ada H Y Yuen Mark David David J Berry Katie Chappell Verena Horneffer-van der Sluis Rachel Shaw Simon Lovestone Paul Elliott John Shockcor John C Lindon Olivier Cloarec Zoltan Takats Elaine Holmes Jeremy K Nicholson

Anal Chem 2016 09 26;88(18):9004-13. Epub 2016 Aug 26.

MRC-NIHR National Phenome Centre, Department of Surgery and Cancer, Imperial College London , IRDB Building, Du Cane Road, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1021/acs.analchem.6b01481DOI Listing
September 2016

Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series.

Authors:
Marc-Emmanuel Dumas Céline Domange Sophie Calderari Andrea Rodríguez Martínez Rafael Ayala Steven P Wilder Nicolas Suárez-Zamorano Stephan C Collins Robert H Wallis Quan Gu Yulan Wang Christophe Hue Georg W Otto Karène Argoud Vincent Navratil Steve C Mitchell John C Lindon Elaine Holmes Jean-Baptiste Cazier Jeremy K Nicholson Dominique Gauguier

Genome Med 2016 09 30;8(1):101. Epub 2016 Sep 30.

Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Sir Alexander Fleming Building, Imperial College, London, SW7 2AZ, UK.

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http://dx.doi.org/10.1186/s13073-016-0352-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045612PMC
September 2016

Urinary Metabotyping of Hepatocellular Carcinoma in a UK Cohort Using Proton Nuclear Magnetic Resonance Spectroscopy.

Authors:
Mohamed I F Shariff Jin U Kim Nimzing G Ladep Mary M E Crossey Larry K Koomson Abigail Zabron Helen Reeves Matthew Cramp Stephen Ryder Shaun Greer I Jane Cox Roger Williams Elaine Holmes Kathryn Nash Simon D Taylor-Robinson

J Clin Exp Hepatol 2016 Sep 20;6(3):186-194. Epub 2016 Apr 20.

Division of Digestive Health, Department of Surgery and Cancer, Imperial College London, St Mary's Campus, South Wharf Road, London W2 1NY, United Kingdom.

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http://dx.doi.org/10.1016/j.jceh.2016.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052404PMC
September 2016

Porcupine quill migration in the thoracic cavity of a German shorthaired pointer.

Authors:
Jose L Guevara Elaine S Holmes Jennifer Reetz David E Holt

J Am Anim Hosp Assoc 2015 Mar-Apr;51(2):101-6. Epub 2015 Feb 19.

From the Dallas Veterinary Surgical Center, Dallas, TX (J.G.); Veterinary Specialty Hospital of the Carolinas, Cary, NC (E.H.); and the University of Pennsylvania, Philadelphia, PA (J.R., D.H.).

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http://jaaha.org/doi/10.5326/JAAHA-MS-6093
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http://dx.doi.org/10.5326/JAAHA-MS-6093DOI Listing
August 2016

Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage.

Authors:
Lindsay M Kindinger David A MacIntyre Yun S Lee Julian R Marchesi Ann Smith Julie A K McDonald Vasso Terzidou Joanna R Cook Christoph Lees Fidan Israfil-Bayli Yazmin Faiza Philip Toozs-Hobson Mark Slack Stefano Cacciatore Elaine Holmes Jeremy K Nicholson T G Teoh Phillip R Bennett

Sci Transl Med 2016 08;8(350):350ra102

Imperial College Parturition Research Group, Division of the Institute of Reproductive and Developmental Biology, Imperial College London, London W12 0NN, UK. Queen Charlotte's Hospital, Imperial College Healthcare National Health Service (NHS) Trust, London W12 0HS, UK.

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http://dx.doi.org/10.1126/scitranslmed.aag1026DOI Listing
August 2016

Role of human milk oligosaccharides in Group B Streptococcus colonisation.

Authors:
Nicholas J Andreas Asmaa Al-Khalidi Mustapha Jaiteh Edward Clarke Matthew J Hyde Neena Modi Elaine Holmes Beate Kampmann Kirsty Mehring Le Doare

Clin Transl Immunology 2016 Aug 26;5(8):e99. Epub 2016 Aug 26.

Department of Paediatrics, Centre for International Child Health, Imperial College London, St Mary's Hospital, London, UK; Wellcome Trust Centre for Global Health Research, London, UK.

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http://dx.doi.org/10.1038/cti.2016.43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007626PMC
August 2016

Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism.

Authors:
Agata Korecka Anthony Dona Shawon Lahiri Adrian James Tett Maha Al-Asmakh Viorica Braniste Rossana D'Arienzo Afrouz Abbaspour Nicole Reichardt Yoshiaki Fujii-Kuriyama Joseph Rafter Arjan Narbad Elaine Holmes Jeremy Nicholson Velmurugesan Arulampalam Sven Pettersson

NPJ Biofilms Microbiomes 2016 24;2:16014. Epub 2016 Aug 24.

Department of Microbiology, Tumour and Cell Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/npjbiofilms.2016.14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515264PMC
August 2016

Increased colonic propionate reduces anticipatory reward responses in the human striatum to high-energy foods.

Authors:
Claire S Byrne Edward S Chambers Habeeb Alhabeeb Navpreet Chhina Douglas J Morrison Tom Preston Catriona Tedford Julie Fitzpatrick Cherag Irani Albert Busza Isabel Garcia-Perez Sofia Fountana Elaine Holmes Anthony P Goldstone Gary S Frost

Am J Clin Nutr 2016 Jul 11;104(1):5-14. Epub 2016 May 11.

Nutrition and Dietetic Research Group, Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine,

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http://dx.doi.org/10.3945/ajcn.115.126706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919527PMC
July 2016

Impact of maternal BMI and sampling strategy on the concentration of leptin, insulin, ghrelin and resistin in breast milk across a single feed: a longitudinal cohort study.

Authors:
Nicholas J Andreas Matthew J Hyde Bronwen R Herbert Suzan Jeffries Shalini Santhakumaran Sundhiya Mandalia Elaine Holmes Neena Modi

BMJ Open 2016 07 7;6(7):e010778. Epub 2016 Jul 7.

Section of Neonatal Medicine, Department of Medicine, Chelsea & Westminster Hospital Campus, Imperial College London, London, UK.

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http://dx.doi.org/10.1136/bmjopen-2015-010778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947729PMC
July 2016

Systemic Characterization of an Obese Phenotype in the Zucker Rat Model Defining Metabolic Axes of Energy Metabolism and Host-Microbial Interactions.

Authors:
Jutarop Phetcharaburanin Hannah Lees Julian R Marchesi Jeremy K Nicholson Elaine Holmes Florian Seyfried Jia V Li

J Proteome Res 2016 06 3;15(6):1897-906. Epub 2016 May 3.

Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London , South Kensington, London SW7 2AZ, United Kingdom.

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http://dx.doi.org/10.1021/acs.jproteome.6b00090DOI Listing
June 2016

Automatic Spectroscopic Data Categorization by Clustering Analysis (ASCLAN): A Data-Driven Approach for Distinguishing Discriminatory Metabolites for Phenotypic Subclasses.

Authors:
Xin Zou Elaine Holmes Jeremy K Nicholson Ruey Leng Loo

Anal Chem 2016 06 13;88(11):5670-9. Epub 2016 May 13.

Medway Metabonomics Research Group, Medway School of Pharmacy, Universities of Kent and Greenwich , Chatham Maritime, Kent, ME4 4TB, U.K.

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http://dx.doi.org/10.1021/acs.analchem.5b04020DOI Listing
June 2016

Multivariate metabotyping of plasma predicts survival in patients with decompensated cirrhosis.

Authors:
Mark J W McPhail Debbie L Shawcross Matthew R Lewis Iona Coltart Elizabeth J Want Charalambos G Antoniades Kiril Veselkov Evangelos Triantafyllou Vishal Patel Oltin Pop Maria Gomez-Romero Michael Kyriakides Rabiya Zia Robin D Abeles Mary M E Crossey Wayel Jassem John O'Grady Nigel Heaton Georg Auzinger William Bernal Alberto Quaglia Muireann Coen Jeremy K Nicholson Julia A Wendon Elaine Holmes Simon D Taylor-Robinson

J Hepatol 2016 May 18;64(5):1058-1067. Epub 2016 Jan 18.

Division of Digestive Health, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, 10th Floor QEQM Wing, St Mary's Hospital Campus, South Wharf Street, London NW1 2NY, United Kingdom.

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http://dx.doi.org/10.1016/j.jhep.2016.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876170PMC
May 2016

Optimized Sample Handling Strategy for Metabolic Profiling of Human Feces.

Authors:
Jasmine Gratton Jutarop Phetcharaburanin Benjamin H Mullish Horace R T Williams Mark Thursz Jeremy K Nicholson Elaine Holmes Julian R Marchesi Jia V Li

Anal Chem 2016 05 21;88(9):4661-8. Epub 2016 Apr 21.

Center for Digestive and Gut Health, Institute of Global Health Innovation, Imperial College London , South Kensington, London SW7 2AZ, U.K.

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http://pubs.acs.org/doi/10.1021/acs.analchem.5b04159
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http://dx.doi.org/10.1021/acs.analchem.5b04159DOI Listing
May 2016

Power Analysis and Sample Size Determination in Metabolic Phenotyping.

Authors:
Benjamin J Blaise Gonçalo Correia Adrienne Tin J Hunter Young Anne-Claire Vergnaud Matthew Lewis Jake T M Pearce Paul Elliott Jeremy K Nicholson Elaine Holmes Timothy M D Ebbels

Anal Chem 2016 05 6;88(10):5179-88. Epub 2016 May 6.

Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London , London SW7 2AZ, U.K.

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http://dx.doi.org/10.1021/acs.analchem.6b00188DOI Listing
May 2016

Hepatocellular carcinoma: Review of disease and tumor biomarkers.

Authors:
Jin Un Kim Mohamed I F Shariff Mary M E Crossey Maria Gomez-Romero Elaine Holmes I Jane Cox Haddy K S Fye Ramou Njie Simon D Taylor-Robinson

World J Hepatol 2016 Apr;8(10):471-84

Jin Un Kim, Mohamed I F Shariff, Mary M E Crossey, Maria Gomez-Romero, Simon D Taylor-Robinson, Division of Digestive Health, Department of Surgery and Cancer, Imperial College London, London W2 1NY, United Kingdom.

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http://dx.doi.org/10.4254/wjh.v8.i10.471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820639PMC
April 2016

Discovery of Infection Associated Metabolic Markers in Human African Trypanosomiasis.

Authors:
Sabrina D Lamour Maria Gomez-Romero Panagiotis A Vorkas Vincent P Alibu Jasmina Saric Elaine Holmes Jeremy M Sternberg

PLoS Negl Trop Dis 2015 27;9(10):e0004200. Epub 2015 Oct 27.

Institute of Biological and Environmental Sciences, University Of Aberdeen, Aberdeen, United Kingdom.

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http://dx.doi.org/10.1371/journal.pntd.0004200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624234PMC
March 2016

An Analytical Pipeline for Quantitative Characterization of Dietary Intake: Application To Assess Grape Intake.

Authors:
Isabel Garcia-Perez Joram M Posma Edward S Chambers Jeremy K Nicholson John C Mathers Manfred Beckmann John Draper Elaine Holmes Gary Frost

J Agric Food Chem 2016 Mar 8;64(11):2423-31. Epub 2016 Mar 8.

Nutrition and Dietetic Research Group, Division of Endocrinology and Metabolism, Imperial College London , London W12 0NN, U.K.

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http://dx.doi.org/10.1021/acs.jafc.5b05878DOI Listing
March 2016

Aspartame sensitivity? A double blind randomised crossover study.

Authors:
Thozhukat Sathyapalan Natalie J Thatcher Richard Hammersley Alan S Rigby Fraser L Courts Alexandros Pechlivanis Nigel J Gooderham Elaine Holmes Carel W le Roux Stephen L Atkin

PLoS One 2015 18;10(3):e0116212. Epub 2015 Mar 18.

Weill Cornell Medical College Qatar, Education City PO Box 24144, Doha, Qatar.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364783PMC
February 2016

Identification of a novel human circulating metabolite of tenofovir disoproxil fumarate with LC-MS/MS.

Authors:
Leanne C Nye Nicola Gray Myra McClure Marta Boffit Elaine Holmes Robert S Plumb Ian D Wilson

Bioanalysis 2015 ;7(6):643-52

Division of Computational & Systems Medicine, Department of Surgery & Cancer, Faculty of Medicine, Imperial College, London, SW7 2AZ, UK.

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http://dx.doi.org/10.4155/bio.14.300DOI Listing
January 2016

Neonatal environment exerts a sustained influence on the development of the intestinal microbiota and metabolic phenotype.

Authors:
Claire A Merrifield Marie C Lewis Bernard Berger Olivier Cloarec Silke S Heinzmann Florence Charton Lutz Krause Nadine S Levin Swantje Duncker Annick Mercenier Elaine Holmes Mick Bailey Jeremy K Nicholson

ISME J 2016 Jan 12;10(1):145-57. Epub 2015 Jun 12.

Biomolecular Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/ismej.2015.90DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681865PMC
January 2016

Development and Validation of a High-Throughput Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry Approach for Screening of Oxylipins and Their Precursors.

Authors:
Arnaud M Wolfer Mathieu Gaudin Simon D Taylor-Robinson Elaine Holmes Jeremy K Nicholson

Anal Chem 2015 Dec 18;87(23):11721-31. Epub 2015 Nov 18.

Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London , Sir Alexander Fleming Building, Exhibition Road, London SW7 2AZ, United Kingdom.

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http://pubs.acs.org/doi/10.1021/acs.analchem.5b02794
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http://dx.doi.org/10.1021/acs.analchem.5b02794DOI Listing
December 2015

Plasma Lipid Profiling in a Rat Model of Hepatocellular Carcinoma: Potential Modulation Through Quinolone Administration.

Authors:
Mohamed I F Shariff Joshua M Tognarelli Matthew R Lewis Elizabeth J Want Fatma El Zahra Mohamed Nimzing G Ladep Mary M E Crossey Shahid A Khan Rajiv Jalan Elaine Holmes Simon D Taylor-Robinson

J Clin Exp Hepatol 2015 Dec 18;5(4):286-94. Epub 2015 Jul 18.

Liver Unit, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jceh.2015.07.205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723654PMC
December 2015

Optimization of metabolite extraction of human vein tissue for ultra performance liquid chromatography-mass spectrometry and nuclear magnetic resonance-based untargeted metabolic profiling.

Authors:
Muzaffar A Anwar Panagiotis A Vorkas Jia V Li Joseph Shalhoub Elizabeth J Want Alun H Davies Elaine Holmes

Analyst 2015 Nov;140(22):7586-97

Section of Biomolecular Medicine, Division of Computational and Systems Biology, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK and Centre for Digestive and Gut Health, Institute of Global Health Innovation, Imperial College London, London, UK.

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http://xlink.rsc.org/?DOI=C5AN01041A
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http://dx.doi.org/10.1039/c5an01041aDOI Listing
November 2015

Perturbations in fatty acid metabolism and apoptosis are manifested in calcific coronary artery disease: An exploratory lipidomic study.

Authors:
Panagiotis A Vorkas Giorgis Isaac Anders Holmgren Elizabeth J Want John P Shockcor Elaine Holmes Michael Y Henein

Int J Cardiol 2015 Oct 23;197:192-9. Epub 2015 Jun 23.

Department of Public Health and Clinical Medicine, Heart Centre, Umea University, Umea, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273150134
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http://dx.doi.org/10.1016/j.ijcard.2015.06.048DOI Listing
October 2015

Bile acid profiling and quantification in biofluids using ultra-performance liquid chromatography tandem mass spectrometry.

Authors:
Magali H Sarafian Matthew R Lewis Alexandros Pechlivanis Simon Ralphs Mark J W McPhail Vishal C Patel Marc-Emmanuel Dumas Elaine Holmes Jeremy K Nicholson

Anal Chem 2015 Oct 30;87(19):9662-70. Epub 2015 Sep 30.

Imperial College of London , Division of Computational Systems Medicine, Department of Surgery and Cancer, Sir Alexander Building, Exhibition Road, South Kensington, London SW7 2AZ, United Kingdom.

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http://dx.doi.org/10.1021/acs.analchem.5b01556DOI Listing
October 2015

Multiplatform characterization of dynamic changes in breast milk during lactation.

Authors:
Nicholas J Andreas Matthew J Hyde Maria Gomez-Romero Maria Angeles Lopez-Gonzalvez Alma Villaseñor Anisha Wijeyesekera Coral Barbas Neena Modi Elaine Holmes Isabel Garcia-Perez

Electrophoresis 2015 Sep 25;36(18):2269-2285. Epub 2015 Jun 25.

Section of Computational and Systems Medicine, Division of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1002/elps.201500011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744768PMC
September 2015

(1)H NMR Spectroscopy of Fecal Extracts Enables Detection of Advanced Colorectal Neoplasia.

Authors:
Aurelien Amiot Anthony C Dona Anisha Wijeyesekera Christophe Tournigand Isabelle Baumgaertner Yann Lebaleur Iradj Sobhani Elaine Holmes

J Proteome Res 2015 Sep 7;14(9):3871-81. Epub 2015 Aug 7.

Section of Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London , SW7 2AZ London, U.K.

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http://dx.doi.org/10.1021/acs.jproteome.5b00277DOI Listing
September 2015

2-Furoylglycine as a Candidate Biomarker of Coffee Consumption.

Authors:
Silke S Heinzmann Elaine Holmes Sunil Kochhar Jeremy K Nicholson Philippe Schmitt-Kopplin

J Agric Food Chem 2015 Sep 22;63(38):8615-21. Epub 2015 Sep 22.

Helmholtz Zentrum München, Research Unit Analytical BioGeoChemistry , 85764 Neuherberg, Germany.

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http://pubs.acs.org/doi/10.1021/acs.jafc.5b03040
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September 2015

Hippocampal Proteomic and Metabonomic Abnormalities in Neurotransmission, Oxidative Stress, and Apoptotic Pathways in a Chronic Phencyclidine Rat Model.

Authors:
Hendrik Wesseling Elizabeth J Want Paul C Guest Hassan Rahmoune Elaine Holmes Sabine Bahn

J Proteome Res 2015 Aug 30;14(8):3174-87. Epub 2015 Jun 30.

†Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge CB2 1QT, U.K.

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http://pubs.acs.org/doi/10.1021/acs.jproteome.5b00105
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http://dx.doi.org/10.1021/acs.jproteome.5b00105DOI Listing
August 2015

The promise of metabolic phenotyping in gastroenterology and hepatology.

Authors:
Elaine Holmes Anisha Wijeyesekera Simon D Taylor-Robinson Jeremy K Nicholson

Nat Rev Gastroenterol Hepatol 2015 Aug 21;12(8):458-71. Epub 2015 Jul 21.

MRC-NIHR National Phenome Centre, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London SW7 2AZ, UK.

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http://dx.doi.org/10.1038/nrgastro.2015.114DOI Listing
August 2015

Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children.

Authors:
Chenhong Zhang Aihua Yin Hongde Li Ruirui Wang Guojun Wu Jian Shen Menghui Zhang Linghua Wang Yaping Hou Haimei Ouyang Yan Zhang Yinan Zheng Jicheng Wang Xiaofei Lv Yulan Wang Feng Zhang Benhua Zeng Wenxia Li Feiyan Yan Yufeng Zhao Xiaoyan Pang Xiaojun Zhang Huaqing Fu Feng Chen Naisi Zhao Bruce R Hamaker Laura C Bridgewater David Weinkove Karine Clement Joel Dore Elaine Holmes Huasheng Xiao Guoping Zhao Shengli Yang Peer Bork Jeremy K Nicholson Hong Wei Huiru Tang Xiaozhuang Zhang Liping Zhao

EBioMedicine 2015 Aug 10;2(8):968-84. Epub 2015 Jul 10.

State Key Laboratory of Microbial Metabolism and Ministry of Education Key Laboratory of Systems Biomedicine, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.

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http://dx.doi.org/10.1016/j.ebiom.2015.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563136PMC
August 2015

Metabolic Profiling of Children Undergoing Surgery for Congenital Heart Disease.

Authors:
Goncalo D S Correia Keng Wooi Ng Anisha Wijeyesekera Sandra Gala-Peralta Rachel Williams S MacCarthy-Morrogh Beatriz Jiménez David Inwald Duncan Macrae Gary Frost Elaine Holmes Nazima Pathan

Crit Care Med 2015 Jul;43(7):1467-76

1Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, United Kingdom. 2School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, United Kingdom. 3Paediatric Intensive Care Unit, Royal Brompton and Harefield NHS Foundation Trust, London, United Kingdom. 4Department of Intensive Care, Southampton General University Hospital, Southampton, United Kingdom. 5Paediatric Intensive Care Unit, Imperial College London NHS Foundation Trust, London, United Kingdom. 6Department of Nutrition and Dietetics, Faculty of Medicine, Imperial College London, United Kingdom. 7University Department of Paediatrics, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://dx.doi.org/10.1097/CCM.0000000000000982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467581PMC
July 2015

Bariatric surgery and nonalcoholic fatty liver disease.

Authors:
Guy Bower Thanos Athanasiou Alberto M Isla Leanne Harling Jia V Li Elaine Holmes Evangelos Efthimiou Ara Darzi Hutan Ashrafian

Eur J Gastroenterol Hepatol 2015 Jul;27(7):755-68

Department of Surgery and Cancer, Imperial College London, Imperial College Healthcare NHS Trust at St Mary's Hospital, London, UK.

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http://dx.doi.org/10.1097/MEG.0000000000000375DOI Listing
July 2015

A new gender-specific model for skin autofluorescence risk stratification.

Authors:
Muhammad S Ahmad Zoheir A Damanhouri Torben Kimhofer Hala H Mosli Elaine Holmes

Sci Rep 2015 May 14;5:10198. Epub 2015 May 14.

1] Drug Metabolism Unit, King Fahad Medical Research Center, King Abdulaziz University, Jeddah, 21589, Saudi Arabia [2] Section of Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, SW7 2AZ, United Kingdom.

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http://www.nature.com/articles/srep10198
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431468PMC
May 2015

Untargeted UPLC-MS profiling pipeline to expand tissue metabolome coverage: application to cardiovascular disease.

Authors:
Panagiotis A Vorkas Giorgis Isaac Muzaffar A Anwar Alun H Davies Elizabeth J Want Jeremy K Nicholson Elaine Holmes

Anal Chem 2015 Apr 8;87(8):4184-93. Epub 2015 Apr 8.

†Biomolecular Medicine, Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London SW7 2AZ, U.K.

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http://pubs.acs.org/doi/10.1021/ac503775m
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http://dx.doi.org/10.1021/ac503775mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407508PMC
April 2015

Urinary metabolic signatures of human adiposity.

Authors:
Paul Elliott Joram M Posma Queenie Chan Isabel Garcia-Perez Anisha Wijeyesekera Magda Bictash Timothy M D Ebbels Hirotsugu Ueshima Liancheng Zhao Linda van Horn Martha Daviglus Jeremiah Stamler Elaine Holmes Jeremy K Nicholson

Sci Transl Med 2015 Apr 29;7(285):285ra62. Epub 2015 Apr 29.

Biomolecular Medicine, Division of Computational and Systems Medicine, MRC-National Institute for Health Research (MRC-NIHR) National Phenome Centre, MRC-PHE Centre for Environment and Health, Department of Surgery and Cancer, Imperial College London, London SW7 2AZ, UK.

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http://dx.doi.org/10.1126/scitranslmed.aaa5680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598200PMC
April 2015

The vaginal microbiome during pregnancy and the postpartum period in a European population.

Authors:
David A MacIntyre Manju Chandiramani Yun S Lee Lindsay Kindinger Ann Smith Nicos Angelopoulos Benjamin Lehne Shankari Arulkumaran Richard Brown Tiong Ghee Teoh Elaine Holmes Jeremy K Nicoholson Julian R Marchesi Phillip R Bennett

Sci Rep 2015 Mar 11;5:8988. Epub 2015 Mar 11.

Imperial College Parturition Research Group, Division of the Institute of Reproduction and Developmental Biology, Imperial College London, UK.

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http://dx.doi.org/10.1038/srep08988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355684PMC
March 2015