Elaine Hayes

Altered Degranulation and pH of Neutrophil Phagosomes Impacts Antimicrobial Efficiency in Cystic Fibrosis.

Authors:

Elaine Hayes Mark P Murphy Kerstin Pohl Niall Browne Karen McQuillan Le Er Saw Clare Foley Fatma Gargoum Oliver J McElvaney Padraig Hawkins Cedric Gunaratnam Noel G McElvaney Emer P Reeves

Front Immunol 2020 18;11:600033. Epub 2020 Dec 18.

Irish Centre for Genetic Lung Disease, Department of Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland.

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December 2020

Neutrophil Membrane Cholesterol Content is a Key Factor in Cystic Fibrosis Lung Disease.

Authors:

Michelle M White Patrick Geraghty Elaine Hayes Stephen Cox William Leitch Bader Alfawaz Gillian M Lavelle Oliver J McElvaney Ryan Flannery Joanne Keenan Paula Meleady Michael Henry Martin Clynes Cedric Gunaratnam Noel G McElvaney Emer P Reeves

EBioMedicine 2017 Sep 16;23:173-184. Epub 2017 Aug 16.

Irish Centre for Genetic Lung Disease, Department of Medicine, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland. Electronic address:

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September 2017

Plaque Size Is Decreased but M1 Macrophage Polarization and Rupture Related Metalloproteinase Expression Are Maintained after Deleting T-Bet in ApoE Null Mice.

Authors:

Aikaterini Tsaousi Elaine M Hayes Karina Di Gregoli Andrew R Bond Laura Bevan Anita C Thomas Andrew C Newby

PLoS One 2016 17;11(2):e0148873. Epub 2016 Feb 17.

School of Clinical Sciences, University of Bristol, Bristol, United Kingdom.

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July 2016

Classical and Alternative Activation and Metalloproteinase Expression Occurs in Foam Cell Macrophages in Male and Female ApoE Null Mice in the Absence of T and B Lymphocytes.

Authors:

Elaine Mo Hayes Aikaterini Tsaousi Karina Di Gregoli S Rhiannon Jenkinson Andrew R Bond Jason L Johnson Laura Bevan Anita C Thomas Andrew C Newby

Front Immunol 2014 28;5:537. Epub 2014 Oct 28.

Bristol Heart Institute, School of Clinical Sciences, University of Bristol , Bristol , UK.

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November 2014

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.

Authors:

Kerstin Pohl Elaine Hayes Joanne Keenan Michael Henry Paula Meleady Kevin Molloy Bakr Jundi David A Bergin Cormac McCarthy Oliver J McElvaney Michelle M White Martin Clynes Emer P Reeves Noel G McElvaney

Blood 2014 Aug 16;124(7):999-1009. Epub 2014 Jun 16.

Respiratory Research Division, Department of Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin, Ireland; and.

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August 2014

A novel neutrophil derived inflammatory biomarker of pulmonary exacerbation in cystic fibrosis.

Authors:

Emer P Reeves David A Bergin Sean Fitzgerald Elaine Hayes Joanne Keenan Michael Henry Paula Meleady Isabel Vega-Carrascal Michelle A Murray Teck Boon Low Cormac McCarthy Emmet O'Brien Martin Clynes Cedric Gunaratnam Noel G McElvaney

J Cyst Fibros 2012 Mar 28;11(2):100-7. Epub 2011 Oct 28.

Respiratory Research Division, Department of Medicine, Royal College of Surgeons in Ireland, Education and Research Centre, Beaumont Hospital, Dublin 9, Ireland.

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March 2012

The cystic fibrosis neutrophil: a specialized yet potentially defective cell.

Authors:

Elaine Hayes Kerstin Pohl Noel G McElvaney Emer P Reeves

Arch Immunol Ther Exp (Warsz) 2011 Apr 11;59(2):97-112. Epub 2011 Feb 11.

Respiratory Research Division, Department of Medicine, Education and Research Centre, Royal College of Surgeons in Ireland, Beaumont Hospital, Dublin 9, Ireland.

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April 2011