Elai Davicioni

Elai Davicioni

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Elai Davicioni

Elai Davicioni

Publications by authors named "Elai Davicioni"

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Genomic Validation of 3-Tiered Clinical Subclassification of High-Risk Prostate Cancer.

Int J Radiat Oncol Biol Phys 2019 Nov 2;105(3):621-627. Epub 2019 Jul 2.

Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.ijrobp.2019.06.2510DOI Listing
November 2019

Genomic Analysis and Treatment Response of a Bladder Urothelial Carcinoma With Sarcomatoid Variant Histology.

Clin Genitourin Cancer 2019 Oct 25;17(5):e888-e892. Epub 2019 May 25.

Department of Urology, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1016/j.clgc.2019.05.019DOI Listing
October 2019

Radiomics Features Measured with Multiparametric Magnetic Resonance Imaging Predict Prostate Cancer Aggressiveness.

J Urol 2019 09 8;202(3):498-505. Epub 2019 Aug 8.

Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

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http://dx.doi.org/10.1097/JU.0000000000000272DOI Listing
September 2019

---Comprehensive transcriptomic profiling identifies breast cancer patients who may be spared adjuvant systemic therapy.

Clin Cancer Res 2019 Sep 26. Epub 2019 Sep 26.

Department of Oncology, Institute of Clinical Sciences, Department of Oncology, Sahlgrenska Academy, University of Gothenburg.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1038DOI Listing
September 2019

The evolution of long noncoding RNA acceptance in prostate cancer initiation, progression, and its clinical utility in disease management.

Eur Urol 2019 Aug 22. Epub 2019 Aug 22.

Vancouver Prostate Centre, Vancouver, BC, Canada; Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2019.07.040DOI Listing
August 2019

Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types.

Clin Cancer Res 2019 Jul 22;25(14):4290-4299. Epub 2019 Apr 22.

Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0404DOI Listing
July 2019

Development of a predictive model for stromal content in prostate cancer samples to improve signature performance.

J Pathol 2019 Jun 17. Epub 2019 Jun 17.

Division of Urology and Cancer Research Program, McGill University Health Centre Research Institute, 1001 Decarie Blvd, Montreal, Quebec, H4A 3J1, Canada.

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http://dx.doi.org/10.1002/path.5315DOI Listing
June 2019

Characterization of transcriptomic signature of primary prostate cancer analogous to prostatic small cell neuroendocrine carcinoma.

Int J Cancer 2019 May 24. Epub 2019 May 24.

Department of Pathology & Laboratory Medicine, Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1002/ijc.32430DOI Listing
May 2019

Genomic Classifier for Guiding Treatment of Intermediate-Risk Prostate Cancers to Dose-Escalated Image Guided Radiation Therapy Without Hormone Therapy.

Int J Radiat Oncol Biol Phys 2019 01 29;103(1):84-91. Epub 2018 Aug 29.

Princess Margaret Cancer Centre, University Health Network, Ontario, Canada; Division of Radiation Oncology, National Cancer Centre Singapore, Singapore; Division of Medical Sciences, National Cancer Centre Singapore, Singapore; Oncology Academic Program, Duke-NUS Medical School, Singapore.

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http://dx.doi.org/10.1016/j.ijrobp.2018.08.030DOI Listing
January 2019

Genomic Risk Predicts Molecular Imaging-detected Metastatic Nodal Disease in Prostate Cancer.

Eur Urol Oncol 2019 Jan 14. Epub 2019 Jan 14.

Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA; Department of Urology, University of California San Francisco, San Francisco, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euo.2018.11.002DOI Listing
January 2019

Clinical and Genomic Characterization of Low-Prostate-specific Antigen, High-grade Prostate Cancer.

Eur Urol 2018 08 22;74(2):146-154. Epub 2018 Feb 22.

Harvard Medical School, Boston, MA, USA; Department of Radiation Oncology, Brigham and Women's Hospital/Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2018.01.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615042PMC
August 2018

Validation of a 10-gene molecular signature for predicting biochemical recurrence and clinical metastasis in localized prostate cancer.

J Cancer Res Clin Oncol 2018 May 6;144(5):883-891. Epub 2018 Mar 6.

Department of Pathology and Laboratory Medicine, University of Calgary, Cumming School of Medicine, Calgary, AB, Canada.

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http://dx.doi.org/10.1007/s00432-018-2615-7DOI Listing
May 2018

Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.

EBioMedicine 2018 May 23;31:182-189. Epub 2018 Apr 23.

Translational Radiobiology Group, Division of Cancer Sciences, University of Manchester, Manchester Academic Health Science Centre, Christie Hospital, Manchester M20 4BX, UK; NIHR Manchester Biomedical Research Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.04.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6014579PMC
May 2018

Stromal Gene Expression is Predictive for Metastatic Primary Prostate Cancer.

Eur Urol 2018 04 19;73(4):524-532. Epub 2017 Mar 19.

Vancouver Prostate Centre & Laboratory for Advanced Genome Analysis, Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada; School of Computing Sciences, Simon Fraser University, Burnaby, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2017.02.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685211PMC
April 2018

Development and Validation of a Novel Integrated Clinical-Genomic Risk Group Classification for Localized Prostate Cancer.

J Clin Oncol 2018 02 29;36(6):581-590. Epub 2017 Nov 29.

Daniel E. Spratt, Robert T. Dess, Adam Cole, Shuang G. Zhao, and Rohit Mehra, University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System, Detroit, MI; Jingbin Zhang, María Santiago-Jiménez, Lucia L.C. Lam, Jijumon Chelliserry, Marguerite du Plessis, Voleak Choeurng, Maria Aranes, Tyler Kolisnik, Jennifer Margrave, Jason Alter, Jennifer Jordan, Christine Buerki, Kasra Yousefi, Zaid Haddad, and Elai Davicioni, GenomeDx Biosciences, Vancouver, British Columbia, Canada; John W. Davis, The University of Texas MD Anderson Cancer Center, Houston, TX; Robert B. Den, Adam P. Dicker, and Edouard J. Trabulsi, Thomas Jefferson University, Philadelphia, PA; Christopher J. Kane, University of California San Diego, San Diego; Edward Uchio, University of California Irvine; Josh M. Randall, Orange County Urology Associates, Irvine; Hao Nguyen, Peter R. Carroll and Felix Y. Feng, University of California San Francisco, San Francisco, CA; Alan Pollack and Radka Stoyanova, University of Miami, Miami, FL; Ashley E. Ross, Johns Hopkins School of Medicine, Baltimore, MD; Andrew G. Glass and Sheila Weinmann, Kaiser Permanente Northwest, Portland, OR; Stacy Loeb, New York University; Ashutosh Tewari, Icahn School of Medicine at Mount Sinai, New York, NY; Edward M. Schaeffer, Northwestern University, Evanston, IL; Eric A. Klein, Cleveland Clinic, Cleveland, OH; R. Jeffrey Karnes, Mayo Clinic, Rochester, MN; and Paul L. Nguyen, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2017.74.2940
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http://dx.doi.org/10.1200/JCO.2017.74.2940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530900PMC
February 2018

Gene expression signatures of neuroendocrine prostate cancer and primary small cell prostatic carcinoma.

BMC Cancer 2017 Nov 13;17(1):759. Epub 2017 Nov 13.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1186/s12885-017-3729-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5683385PMC
November 2017

Pan-Cancer Analysis of Genomic Sequencing Among the Elderly.

Int J Radiat Oncol Biol Phys 2017 07 7;98(4):726-732. Epub 2017 Jan 7.

Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2017.01.002DOI Listing
July 2017

Transcriptome evaluation of the relation between body mass index and prostate cancer outcomes.

Cancer 2017 Jun 31;123(12):2240-2247. Epub 2017 Jan 31.

Department of Radiation Oncology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1002/cncr.30580DOI Listing
June 2017

Genomic Classifier Augments the Role of Pathological Features in Identifying Optimal Candidates for Adjuvant Radiation Therapy in Patients With Prostate Cancer: Development and Internal Validation of a Multivariable Prognostic Model.

J Clin Oncol 2017 Jun 28;35(18):1982-1990. Epub 2017 Mar 28.

Deepansh Dalela, Mani Menon, and Firas Abdollah, Henry Ford Health System, Detroit, MI; María Santiago-Jiménez, Kasra Yousefi, and Elai Davicioni, GenomeDx Biosciences, Vancouver, British Columbia, Canada; R. Jeffrey Karnes, Mayo Clinic, Rochester, MN; Ashley E. Ross, Johns Hopkins Hospital, Baltimore, MD; Adam P. Dicker and Robert B. Den, Thomas Jefferson University, Philadelphia, PA; Stephen J. Freedland, Cedars-Sinai Medical Center, Los Angeles, CA; Edward M. Schaeffer, Northwestern University Feinberg School of Medicine, Chicago, IL; and Alberto Briganti, Vita Salute San Raffaele Hospital, Milan, Italy.

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http://dx.doi.org/10.1200/JCO.2016.69.9918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530898PMC
June 2017

Individual Patient-Level Meta-Analysis of the Performance of the Decipher Genomic Classifier in High-Risk Men After Prostatectomy to Predict Development of Metastatic Disease.

J Clin Oncol 2017 Jun 30;35(18):1991-1998. Epub 2017 Mar 30.

Daniel E. Spratt and Shuang G. Zhao, University of Michigan, Ann Arbor; Firas Abdollah, Henry Ford Health System, Detroit, MI; Kasra Yousefi, Samineh Deheshi, Jingbin Zhang, Lucia L.C. Lam, Marguerite du Plessis, Voleak Choeurng, Zaid Haddad, Christine Buerki, and Elai Davicioni, GenomeDx Biosciences, Vancouver, British Columbia, Canada; Ashley E. Ross and Bruce J. Trock, Johns Hopkins Hospital, Baltimore, MD; Robert B. Den and Adam P. Dicker, Thomas Jefferson University, Philadelphia, PA; Edward M. Schaeffer, Northwestern University, Evanston, IL; Andrew G. Glass and Sheila Weinmann, Center for Health Research, Kaiser Permanente Northwest, Portland, OR; Stephen J. Freedland, Cedars-Sinai Medical Center, Los Angeles; Felix Y. Feng, University of California, San Francisco, CA; Eric A. Klein, Cleveland Clinic, Cleveland, OH; and R. Jeffrey Karnes, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1200/JCO.2016.70.2811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530581PMC
June 2017

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer.

Cell Rep 2017 06;19(10):2045-2059

Centre for Molecular Medicine Norway, Nordic European Molecular Biology Laboratory Partnership, Forskningsparken, University of Oslo, 21 0349 Oslo, Norway; Department of Molecular Oncology, Institute for Cancer Research, Oslo University Hospital, 0424 Oslo, Norway; PCUK Movember Centre of Excellence, CCRCB, Queen's University, Belfast BT7 1NN, Northern Ireland, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.05.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675034PMC
June 2017

Comprehensive Determination of Prostate Tumor ETS Gene Status in Clinical Samples Using the CLIA Decipher Assay.

J Mol Diagn 2017 05 21;19(3):475-484. Epub 2017 Mar 21.

Department of Pathology, Johns Hopkins School of Medicine, Baltimore, Maryland; Department of Oncology, Johns Hopkins School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2017.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417038PMC
May 2017

Multi-institutional Analysis Shows that Low PCAT-14 Expression Associates with Poor Outcomes in Prostate Cancer.

Eur Urol 2017 02 22;71(2):257-266. Epub 2016 Jul 22.

Department of Internal Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA; Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA; Beaumont Hospital-Dearborn, Transitional Year Program, Dearborn, MI, USA; Department of Biomedical Engineering, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2016.07.012DOI Listing
February 2017

Development and validation of a 24-gene predictor of response to postoperative radiotherapy in prostate cancer: a matched, retrospective analysis.

Lancet Oncol 2016 Nov 12;17(11):1612-1620. Epub 2016 Oct 12.

Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Radiation Oncology, University of California at San Francisco, San Francisco, CA, USA; Department of Medicine, University of California at San Francisco, San Francisco, CA, USA; Helen Diller Comprehensive Cancer Center, University of California at San Francisco, San Francisco, CA, USA. Electronic address:

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http://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(
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http://dx.doi.org/10.1016/S1470-2045(16)30491-0DOI Listing
November 2016

Prediction of Lymph Node Metastasis in Patients with Bladder Cancer Using Whole Transcriptome Gene Expression Signatures.

J Urol 2016 Oct 19;196(4):1036-41. Epub 2016 Apr 19.

Department of Urologic Sciences, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.04.061DOI Listing
October 2016

Integrated Classification of Prostate Cancer Reveals a Novel Luminal Subtype with Poor Outcome.

Cancer Res 2016 09 14;76(17):4948-58. Epub 2016 Jun 14.

Division of Cancer Biology and Therapeutics, Departments of Surgery & Biomedical Sciences, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047668PMC
http://dx.doi.org/10.1158/0008-5472.CAN-16-0902DOI Listing
September 2016

Prostate cancer radiomics and the promise of radiogenomics.

Transl Cancer Res 2016 Aug;5(4):432-447

Department of Radiation Oncology, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703221PMC
August 2016

AXIN2 expression predicts prostate cancer recurrence and regulates invasion and tumor growth.

Prostate 2016 May 15;76(6):597-608. Epub 2016 Jan 15.

Division of Medical Oncology, Department of Medicine, University of Southern California Keck School of Medicine and Translational and Clinical Science Program, USC Norris Comprehensive Cancer Center, Los Angeles, California.

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http://dx.doi.org/10.1002/pros.23151DOI Listing
May 2016

Application of a Clinical Whole-Transcriptome Assay for Staging and Prognosis of Prostate Cancer Diagnosed in Needle Core Biopsy Specimens.

J Mol Diagn 2016 05 3;18(3):395-406. Epub 2016 Mar 3.

Department of Urology, University of California San Francisco, San Francisco, California; Department of Anatomic Pathology, University of California San Francisco, San Francisco, California.

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http://dx.doi.org/10.1016/j.jmoldx.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851733PMC
May 2016

The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer.

Clin Cancer Res 2016 Apr 2;22(7):1777-86. Epub 2015 Dec 2.

Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan. Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan. Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan.

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http://clincancerres.aacrjournals.org/content/early/2016/01/
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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-15-1250DOI Listing
April 2016

Characterization of 1577 primary prostate cancers reveals novel biological and clinicopathologic insights into molecular subtypes.

Eur Urol 2015 Oct 8;68(4):555-67. Epub 2015 May 8.

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2015.04.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562381PMC
October 2015

Androgen-Regulated SPARCL1 in the Tumor Microenvironment Inhibits Metastatic Progression.

Cancer Res 2015 Oct 20;75(20):4322-34. Epub 2015 Aug 20.

The James Buchanan Brady Urological Institute, Department of Urology, Johns Hopkins University, Baltimore, Maryland. The Department of Oncology, Johns Hopkins University, Baltimore, Maryland. The Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609262PMC
October 2015

Novel Biomarker Signature That May Predict Aggressive Disease in African American Men With Prostate Cancer.

J Clin Oncol 2015 Sep 20;33(25):2789-96. Epub 2015 Jul 20.

Kosj Yamoah, Robert Den, and Adam P. Dicker, Thomas Jefferson University Hospital; Priti Lal, Michael Feldman, and Timothy R. Rebbeck, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA; Kosj Yamoah, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Michael H. Johnson, Farzana A. Faisal, Ashley E. Ross, and Edward M. Schaeffer, Johns Hopkins University, Baltimore, MD; Voleak Choeurng, Kasra Yousefi, Zaid Haddad, Mohammed Alshalafa, and Elai Davicioni, GenomeDx Biosciences, Vancouver, British Columbia, Canada; and Eric A. Klein, The Cleveland Clinic Foundation, Cleveland, OH.

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http://dx.doi.org/10.1200/JCO.2014.59.8912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4550692PMC
September 2015

DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.

Cancer Cell 2015 Jul;28(1):97-113

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Urology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531387PMC
July 2015