Publications by authors named "Einars Loza"

14Publications

Synthesis and evaluation of (E)-2-(5-phenylpent-2-en-4-ynamido)cyclohex-1-ene-1-carboxylate derivatives as HCA2 receptor agonists.

Bioorg Med Chem 2017 08 21;25(16):4314-4329. Epub 2017 Jun 21.

Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.06.028DOI Listing
August 2017

Suppression of intestinal microbiota-dependent production of pro-atherogenic trimethylamine N-oxide by shifting L-carnitine microbial degradation.

Life Sci 2014 Nov 7;117(2):84-92. Epub 2014 Oct 7.

Latvian Institute of Organic Synthesis, Aizkraukles Str. 21, Riga, LV-1006, Latvia; Rigas Stradins University, Dzirciema Str. 16, Riga, LV-1007, Latvia.

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http://dx.doi.org/10.1016/j.lfs.2014.09.028DOI Listing
November 2014

Synthesis and evaluation of (E)-2-(acrylamido)cyclohex-1-enecarboxylic acid derivatives as HCA1, HCA2, and HCA3 receptor agonists.

Bioorg Med Chem 2014 Jul 17;22(14):3654-69. Epub 2014 May 17.

Latvian Institute of Organic Synthesis, Aizkraukles 21, Riga LV-1006, Latvia. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2014.05.011DOI Listing
July 2014

Selective inhibition of OCTN2 is more effective than inhibition of gamma-butyrobetaine dioxygenase to decrease the availability of l-carnitine and to reduce myocardial infarct size.

Pharmacol Res 2014 Jul 14;85:33-8. Epub 2014 May 14.

Latvian Institute of Organic Synthesis, Aizkraukles Str. 21, Riga LV1006, Latvia; Riga Stradins University, Faculty of Pharmacy, Dzirciema Str. 16, Riga LV1007, Latvia.

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http://dx.doi.org/10.1016/j.phrs.2014.05.002DOI Listing
July 2014

LC-MS/MS assay for the quantitation of the HDAC inhibitor belinostat and five major metabolites in human plasma.

J Pharm Biomed Anal 2013 Jul-Aug;81-82:89-98. Epub 2013 Apr 9.

Molecular Therapeutics Drug Discovery Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213-1863, USA.

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http://dx.doi.org/10.1016/j.jpba.2013.03.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663884PMC
December 2013

Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei.

Bioorg Med Chem Lett 2012 Mar 28;22(5):1886-90. Epub 2012 Jan 28.

Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S0960894X120010
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http://dx.doi.org/10.1016/j.bmcl.2012.01.072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314994PMC
March 2012