Publications

Structural basis for intramolecular interaction of post-translationally modified H-Ras•GTP prepared by protein ligation.
FEBS Lett 2017 Jul 20. Epub 2017 Jul 20.
Division of Molecular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Chuo-ku, Kobe, Japan.










Structure-based design of a streptavidin mutant specific for an artificial biotin analogue.
J Biochem 2015 Jun 2;157(6):467-75. Epub 2015 Feb 2.
Division of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan; Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo 153-8904, Japan; and Radioisotope Center, The University of Tokyo, 2-11-16 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan



The N-terminal acidic residue of the cytosolic helix 8 of an odorant receptor is responsible for different response dynamics via G-protein.
FEBS Lett 2015 Apr 31;589(10):1136-42. Epub 2015 Mar 31.
Health Research Institute, National Institute of Advanced Industrial Science and Technology, 3-11-46 Nakoji, Amagasaki, Hyogo 661-0974, Japan. Electronic address:



Water-mediated recognition of simple alkyl chains by heart-type fatty-acid-binding protein.
Angew Chem Int Ed Engl 2015 Jan 9;54(5):1508-11. Epub 2014 Dec 9.
JST-ERATO and Graduate School of Science, Osaka University, Machikaneyama, Toyonaka, Osaka 560-0043 (Japan); Project Research Centre for Fundamental Science, Osaka University, Machikaneyama, Toyonaka, Osaka 560-0043 (Japan).

In vivo crystallography at X-ray free-electron lasers: the next generation of structural biology?
Philos Trans R Soc Lond B Biol Sci 2014 Jul;369(1647):20130497
Photon Factory, High Energy Accelerator Research Organization, 1-1 Oho, Tsukuba, Ibaraki 305-0801, Japan Center for Free-Electron Laser science, Notkestrasse 85, Building 99, Hamburg 22607, Germany

Structural insights into the function of a thermostable copper-containing nitrite reductase.
J Biochem 2014 Feb 30;155(2):123-35. Epub 2013 Nov 30.
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan; Department of Chemistry, Graduate School of Science, Osaka University, 1-1 Machikaneyama, Toyonaka, Osaka 560-0043, Japan; Department of Applied Chemistry, School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan; Faculty of Life and Environmental Sciences, Department of Environmental Information, Kyoto Prefectural University, Shimogamo-Hanki-cho, Sakyou, Kyoto 606-8522, Japan; Molecular-Recognition Structure Analysis Team, Molecular Profiling Research Center for Drug Discovery (molprof) National Institute of Advanced Industrial Science and Technology (AIST) 2-3-26 Aomi, Koto-ku, Tokyo 135-0064, Japan; Microbial Genome Research Group, Japan Agency of Marine-Earth Science and Technology, 2-15 Natsushima, Yokosuka, Kanagawa 237-0061, Japan; and RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo, Hyogo 679-5148, Japan.


Construction and characterization of functional anti-epiregulin humanized monoclonal antibodies.
Biochem Biophys Res Commun 2013 Nov 12;441(4):1011-7. Epub 2013 Nov 12.
Laboratory for Systems Biology and Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan; Department of Life Sciences, Graduate School of Arts and Sciences, The University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo 153-8902, Japan.


Expression, purification, crystallization and preliminary crystallographic study of FtsA from methicillin-resistant Staphylococcus aureus.
Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 Aug 27;69(Pt 8):895-8. Epub 2013 Jul 27.
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.


Crystallization and preliminary X-ray crystallographic analysis of UDP-glucuronic acid:flavonol-3-O-glucuronosyltransferase (VvGT5) from the grapevine Vitis vinifera.
Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 Jan 25;69(Pt 1):65-8. Epub 2012 Dec 25.
Division of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan.

Crystal structure of rice Rubisco and implications for activation induced by positive effectors NADPH and 6-phosphogluconate.
J Mol Biol 2012 Sep 17;422(1):75-86. Epub 2012 May 17.
Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1, Yamadaoka, Suita, Osaka 565-0871, Japan.


Crystallization and preliminary X-ray diffraction analysis of orotate phosphoribosyltransferase from the human malaria parasite Plasmodium falciparum.
Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Feb 27;68(Pt 2):244-6. Epub 2012 Jan 27.
Division of Applied Chemistry, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan.



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