Publications by authors named "Eiichi Araki"

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Efficacy and safety of pemafibrate (K-877), a selective peroxisome proliferator-activated receptor α modulator, in patients with dyslipidemia: Results from a 24-week, randomized, double blind, active-controlled, phase 3 trial.
J Clin Lipidol 2018 Jan - Feb;12(1):173-184. Epub 2017 Oct 28.
Department of Community Medicine and Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan; Department of Cardiovascular Medicine, Rinku General Medical Center, Izumisano, Japan.


Inhibition of Local Macrophage Growth Ameliorates Focal Inflammation and Suppresses Atherosclerosis.
Arterioscler Thromb Vasc Biol 2018 Mar 1. Epub 2018 Mar 1.
From the Department of Metabolic Medicine (S.Y., T.S., T.M., Y.M., N.I., K.F., S.M., S.N., S.K., H.M., N.F., E.A.), Department of Cell Pathology (Y.K., Y.F., M.T.), Department of Medical Biochemistry (K.Y.), and Department of Medical Cell Biology (T.K.), Faculty of Life Sciences, Kumamoto University, Japan.



Acetate alters expression of genes involved in beige adipogenesis in 3T3-L1 cells and obese KK-Ay mice.
J Clin Biochem Nutr 2016 Nov 8;59(3):207-214. Epub 2016 Sep 8.
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.


Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial.
Atherosclerosis 2016 Jun 26;249:36-43. Epub 2016 Feb 26.
Laboratory for Systems Biology and Medicine (LSBM), Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904, Japan. Electronic address:

Non-invasive measurement of skin autofluorescence to evaluate diabetic complications.
J Clin Biochem Nutr 2016 Mar 20;58(2):135-40. Epub 2016 Jan 20.
Laboratory of Food and Regulation Biology, Graduate School of Agriculture, Tokai University, Kawayou, Minamiaso, Aso-gun, Kumamoto 869-1404, Japan.




Long-term safety and efficacy of tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2, as monotherapy or in combination with other oral antidiabetic agents in Japanese patients with type 2 diabetes mellitus: multicenter, open-label, randomized controlled trials.
Expert Opin Pharmacother 2014 Apr 11;15(6):749-66. Epub 2014 Feb 11.
Yamaguchi University Graduate School of Medicine, Division of Endocrinology, Metabolism, Hematological Science and Therapeutics , 1-1-1 Minami-Kogushi, Ube, Yamaguchi 755-8505 , Japan +81 836 22 2250 (office) ; +81 836 22 2256 ;





Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.
Cardiovasc Diabetol 2013 Nov 4;12:160. Epub 2013 Nov 4.
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Chuo Ward, Kumamoto 860-8556, Japan.

Insulin receptor activation through its accumulation in lipid rafts by mild electrical stress.
J Cell Physiol 2013 Feb;228(2):439-46
Department of Molecular Medicine, Global COE Cell Fate Regulation Research and Education Unit, Kumamoto University, Kumamoto, Japan.

Apocynin suppresses the progression of atherosclerosis in apoE-deficient mice by inactivation of macrophages.
Biochem Biophys Res Commun 2013 Feb 11;431(2):124-30. Epub 2013 Jan 11.
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan.

Regulation of TNFα converting enzyme activity in visceral adipose tissue of obese mice.
Biochem Biophys Res Commun 2013 Jan 27;430(4):1189-94. Epub 2012 Dec 27.
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

The impact of Ca²⁺/calmodulin-dependent protein kinase II on insulin gene expression in MIN6 cells.
Biochem Biophys Res Commun 2012 May 25;421(4):801-7. Epub 2012 Apr 25.
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.


An intervention study to promote self-improvement of lifestyle in a Japanese community: a new health support program.
Environ Health Prev Med 2011 Jul 18;16(4):253-63. Epub 2011 Jan 18.
Department of Nursing, Kyushu University of Nursing and Social Welfare, 888 Tomio, Tamana, Kumamoto, 865-0062, Japan.


Voltage-gated K+ channel KCNQ1 regulates insulin secretion in MIN6 β-cell line.
Biochem Biophys Res Commun 2011 Apr 21;407(3):620-5. Epub 2011 Mar 21.
Department of Medical Biochemistry, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860 8556, Japan.

Caloric restriction decreases ER stress in liver and adipose tissue in ob/ob mice.
Biochem Biophys Res Commun 2011 Jan 4;404(1):339-44. Epub 2010 Dec 4.
Department of Metabolic Medicine, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan.



Kif26b, a kinesin family gene, regulates adhesion of the embryonic kidney mesenchyme.
Proc Natl Acad Sci U S A 2010 May 3;107(20):9240-5. Epub 2010 May 3.
Department of Kidney Development, Institute of Molecular Embryology and Genetics, Kumamoto University, Kumamoto 860-0811, Japan.



Mild electrical stimulation increases ubiquitinated proteins and Hsp72 in A549 cells via attenuation of proteasomal degradation.
J Pharmacol Sci 2008 Oct 10;108(2):222-6. Epub 2008 Oct 10.
Department of Molecular Medicine, Graduate School of Pharmaceutical Sciences, Global COE "Cell Fate Regulation Research and Education Unit", Kumamoto University, 5-1 Oe-honmachi, Kumamoto, Japan.

Mild electrical stimulation with heat shock ameliorates insulin resistance via enhanced insulin signaling.
PLoS One 2008 30;3(12):e4068. Epub 2008 Dec 30.
Department of Molecular Medicine, Faculty of Medical and Pharmaceutical Sciences, Global COE Cell Fate Regulation Research and Education Unit, Kumamoto University, Kumamoto, Japan.










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