Efstathios S Gonos

Efstathios S Gonos

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Efstathios S Gonos

Efstathios S Gonos

Publications by authors named "Efstathios S Gonos"

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Protein synthesis inhibition induces proteasome assembly and function.

Biochem Biophys Res Commun 2019 Jun 24;514(1):224-230. Epub 2019 Apr 24.

Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, 48 Vassileos Constantinou Ave., Athens, 11635, Greece; Örebro University, Medical School, Örebro, 701 82, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X193075
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http://dx.doi.org/10.1016/j.bbrc.2019.04.114DOI Listing
June 2019

Where ageing goes nowadays: Mechanisms, pathways, biomarkers and anti-ageing strategies.

Mech Ageing Dev 2019 01 18;177:1-3. Epub 2018 Dec 18.

Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Belgrade, Serbia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00476374183025
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http://dx.doi.org/10.1016/j.mad.2018.12.002DOI Listing
January 2019

Stress and Senescence: A Special Issue dedicated to Olivier Toussaint.

Mech Ageing Dev 2018 03;170

National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, Athens, Greece.

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http://dx.doi.org/10.1016/j.mad.2018.02.003DOI Listing
March 2018

Anti-ageing properties of Khelma Longevity™: treatment of human fibroblasts increases proteasome levels and decreases the levels of oxidized proteins.

N Biotechnol 2017 Sep 6;38(Pt A):36-39. Epub 2017 Mar 6.

National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, 48 Vassileos Constantinou Ave., 11635 Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.nbt.2017.03.002DOI Listing
September 2017

Human mesenchymal stem cells with enhanced telomerase activity acquire resistance against oxidative stress-induced genomic damage.

Cytotherapy 2017 07 25;19(7):808-820. Epub 2017 Apr 25.

Biohellenika Biotechnology Company, 57001 Thessaloniki, Greece; Department of Biological Chemistry, Medical School, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.

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https://linkinghub.elsevier.com/retrieve/pii/S14653249173054
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http://dx.doi.org/10.1016/j.jcyt.2017.03.078DOI Listing
July 2017

Proteasome activation enhances stemness and lifespan of human mesenchymal stem cells.

Free Radic Biol Med 2017 02 27;103:226-235. Epub 2016 Dec 27.

National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry & Biotechnology, 48 Vas. Constantinou Ave., Athens 11635, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.12.035DOI Listing
February 2017

18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures.

Antioxid Redox Signal 2016 12 30;25(16):855-869. Epub 2016 Mar 30.

1 Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation , Athens, Greece .

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http://dx.doi.org/10.1089/ars.2015.6494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5124744PMC
December 2016

Interventions for age-related diseases: Shifting the paradigm.

Mech Ageing Dev 2016 12 29;160:69-92. Epub 2016 Sep 29.

MRC Arthiritis Research UK Centre for Integrated Research into Musculoskeletal Ageing (CIMA), Department of Oncology and Metabolism, University of Sheffield, The Medical School, Sheffield, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2016.09.009DOI Listing
December 2016

Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing.

Oxid Med Cell Longev 2015 21;2015:732914. Epub 2015 Apr 21.

Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis, 15784 Athens, Greece.

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http://dx.doi.org/10.1155/2015/732914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419258PMC
April 2016

MARK-AGE population: From the human model to new insights.

Mech Ageing Dev 2015 Nov 2;151:13-7. Epub 2015 Apr 2.

DIMES-Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy; CIG-Interdepartmental Centre "L.Galvani", Alma Mater Studiorum, University of Bologna, 40126 Bologna, Italy.

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http://dx.doi.org/10.1016/j.mad.2015.03.010DOI Listing
November 2015

Protein modification and maintenance systems as biomarkers of ageing.

Mech Ageing Dev 2015 Nov 3;151:71-84. Epub 2015 Apr 3.

Sorbonne Universités, UPMC University Paris 06, UMR 8256, Biological adaptation and ageing - IBPS, F-75005 Paris, France; CNRS-UMR 8256, F-75005 Paris, France; INSERM U1164, F-75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2015.03.009DOI Listing
November 2015

Editorial.

Mech Ageing Dev 2015 Nov 14;151. Epub 2015 Sep 14.

Department of Molecular Gerontology, NIA, Baltimore, MD 21224-6825, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00476374150009
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http://dx.doi.org/10.1016/j.mad.2015.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193536PMC
November 2015

Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases.

Ageing Res Rev 2015 Sep 23;23(Pt A):37-55. Epub 2014 Dec 23.

National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, 48 Vas. Constantinou Ave., 116 35 Athens, Greece; Örebro University, Medical School, Örebro, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2014.12.003DOI Listing
September 2015

Aging and longevity between genetic background and lifestyle intervention.

Biomed Res Int 2014 27;2014:516402. Epub 2014 May 27.

Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, 11635 Athens, Greece.

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http://www.hindawi.com/journals/bmri/2014/516402/
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http://dx.doi.org/10.1155/2014/516402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058245PMC
February 2015

20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegans.

FASEB J 2015 Feb 13;29(2):611-22. Epub 2014 Nov 13.

Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens, Greece; and

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http://www.fasebj.org/doi/10.1096/fj.14-252189
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http://dx.doi.org/10.1096/fj.14-252189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314225PMC
February 2015

Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review.

Mech Ageing Dev 2014 Mar-Apr;136-137:29-49. Epub 2014 Jan 2.

Department of Clinical and Experimental Biomedical Sciences, University of Florence, Viale Morgagni, 50, 50134 Florence, Italy.

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http://dx.doi.org/10.1016/j.mad.2013.12.007DOI Listing
December 2014

Optimization of in vitro measurement of proteasome activity in mammalian cells using fluorogenic substrates.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S31. Epub 2014 Dec 10.

National Hellenic Research Foundation (Institute of Biology, Medicinal Chemistry & Biotechnology), Greece.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.762DOI Listing
October 2014

Microwave-assisted synthesis of 3,5-disubstituted isoxazoles and evaluation of their anti-ageing activity.

Eur J Med Chem 2014 Aug 24;83:508-15. Epub 2014 Jun 24.

National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, 48 Vas. Constantinou Ave, Athens 11635, Greece.

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http://dx.doi.org/10.1016/j.ejmech.2014.06.046DOI Listing
August 2014

Proteasome activation delays aging in vitro and in vivo.

Free Radic Biol Med 2014 Jun 27;71:303-20. Epub 2014 Mar 27.

National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry, and Biotechnology, 116 35 Athens, Greece; Örebro University Medical School, Örebro, Sweden.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.03.031DOI Listing
June 2014

Protein damage, repair and proteolysis.

Mol Aspects Med 2014 Feb 26;35:1-71. Epub 2012 Oct 26.

Institute of Biology, Medicinal Chemistry and Biotechnology, National Helenic Research Foundation, 48 Vas. Constantinou Ave., 116 35 Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2012.09.001DOI Listing
February 2014

Structure and function of the ubiquitin-proteasome system: modulation of components.

Prog Mol Biol Transl Sci 2012 ;109:41-74

National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, Athens, Greece.

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https://linkinghub.elsevier.com/retrieve/pii/B97801239786390
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http://dx.doi.org/10.1016/B978-0-12-397863-9.00002-XDOI Listing
September 2013

The 19S proteasome subunit Rpn7 stabilizes DNA damage foci upon genotoxic insult.

IUBMB Life 2012 May 31;64(5):432-42. Epub 2012 Mar 31.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vassileos Constantinou Avenue, Athens, Greece.

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http://doi.wiley.com/10.1002/iub.1018
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http://dx.doi.org/10.1002/iub.1018DOI Listing
May 2012

CHIP E3 ligase regulates mammalian senescence by modulating the levels of oxidized proteins.

Mech Ageing Dev 2011 May 12;132(5):269-72. Epub 2011 Apr 12.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, Athens, Greece.

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https://linkinghub.elsevier.com/retrieve/pii/S00476374110004
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http://dx.doi.org/10.1016/j.mad.2011.04.003DOI Listing
May 2011

CHIP-dependent p53 regulation occurs specifically during cellular senescence.

Free Radic Biol Med 2011 Jan 23;50(1):157-65. Epub 2010 Oct 23.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, Athens 11635, Greece.

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https://linkinghub.elsevier.com/retrieve/pii/S08915849100132
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http://dx.doi.org/10.1016/j.freeradbiomed.2010.10.701DOI Listing
January 2011

Anti-ageing and rejuvenating effects of quercetin.

Exp Gerontol 2010 Oct 7;45(10):763-71. Epub 2010 Jul 7.

Institute of Biological Research and Biotechnology, Athens, Greece.

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https://linkinghub.elsevier.com/retrieve/pii/S05315565100021
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http://dx.doi.org/10.1016/j.exger.2010.07.001DOI Listing
October 2010

Proteasome function determines cellular homeostasis and the rate of aging.

Adv Exp Med Biol 2010 ;694:38-46

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vas. Constantinou Ave., Athens 11635, Greece.

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http://dx.doi.org/10.1007/978-1-4419-7002-2_4DOI Listing
October 2010

Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts.

J Biol Chem 2010 Mar 12;285(11):8171-84. Epub 2010 Jan 12.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vassileos Constantinou Avenue, Athens 11635, Greece.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.031575
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http://dx.doi.org/10.1074/jbc.M109.031575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832969PMC
March 2010

Chapter 9: Oxidative stress in malignant progression: The role of Clusterin, a sensitive cellular biosensor of free radicals.

Adv Cancer Res 2009 ;104:171-210

Department of Cell Biology and Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis Zografou, Athens 15784, Greece.

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http://dx.doi.org/10.1016/S0065-230X(09)04009-3DOI Listing
January 2010

Genome-wide transcriptome profile of the human osteosarcoma Sa OS and U-2 OS cell lines.

Cancer Genet Cytogenet 2010 Jan;196(2):109-18

Department of Cell Biology & Biophysics, Faculty of Biology, University of Athens, Panepistimiopolis Zografou, Athens 15784, Greece.

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http://dx.doi.org/10.1016/j.cancergencyto.2009.09.012DOI Listing
January 2010

Transcriptional and posttranslational regulation of clusterin by the two main cellular proteolytic pathways.

Free Radic Biol Med 2009 May;46(9):1267-74

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vas. Constantinou Avenue, Athens, Greece.

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http://dx.doi.org/10.1016/j.freeradbiomed.2009.01.025DOI Listing
May 2009

Advances and challenges in basic and translational research on clusterin.

Cancer Res 2009 Jan;69(2):403-6

Laboratory of Molecular and Cellular Aging, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Avenue, Athens, Greece.

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http://cancerres.aacrjournals.org/content/canres/69/2/403.fu
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-08-2912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848483PMC
January 2009

Proteasome activation as a novel antiaging strategy.

IUBMB Life 2008 Oct;60(10):651-5

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, Athens 11635, Greece.

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http://dx.doi.org/10.1002/iub.99DOI Listing
October 2008

Partial proteasome inhibition in human fibroblasts triggers accelerated M1 senescence or M2 crisis depending on p53 and Rb status.

Aging Cell 2008 Oct 1;7(5):717-32. Epub 2008 Aug 1.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, Athens, Greece.

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http://doi.wiley.com/10.1111/j.1474-9726.2008.00425.x
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http://dx.doi.org/10.1111/j.1474-9726.2008.00425.xDOI Listing
October 2008

Exposure of human diploid fibroblasts to hypoxia extends proliferative life span.

Ann N Y Acad Sci 2007 Nov;1119:9-19

Laboratory of Molecular & Cellular Aging, Institute of Biological Research & Biotechnology, National Hellenic Research Foundation, Athens 11635, Greece.

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http://dx.doi.org/10.1196/annals.1404.025DOI Listing
November 2007

Overexpression of hUMP1/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence.

Exp Gerontol 2007 Sep 4;42(9):899-903. Epub 2007 Feb 4.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vas. Constantinou Ave., Athens 116 35, Greece.

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http://dx.doi.org/10.1016/j.exger.2007.01.012DOI Listing
September 2007

Clusterin/Apolipoprotein J up-regulation after zinc exposure, replicative senescence or differentiation of human haematopoietic cells.

Biogerontology 2006 Oct-Dec;7(5-6):375-82

Laboratory of Molecular & Cellular Ageing, Institute of Biological Research & Biotechnology, National Hellenic Research Foundation, 48 Vas. Constantinou Ave., Athens, 11635, Greece.

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http://link.springer.com/10.1007/s10522-006-9052-8
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http://dx.doi.org/10.1007/s10522-006-9052-8DOI Listing
August 2007

The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts.

Rejuvenation Res 2007 Jun;10(2):157-72

Institute of Biological Research and Biotechnology, Laboratory of Molecular and Cellular Aging, National Hellenic Research Foundation, Athens, Greece.

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https://www.liebertpub.com/doi/10.1089/rej.2006.0513
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http://dx.doi.org/10.1089/rej.2006.0513DOI Listing
June 2007

Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of Clusterin/Apolipoprotein J.

Int J Cancer 2007 Feb;120(3):611-22

Laboratory of Molecular & Cellular Ageing, Institute of Biological Research & Biotechnology, National Hellenic Research Foundation, Athens 11635, Greece.

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http://dx.doi.org/10.1002/ijc.22327DOI Listing
February 2007

Regulation of clusterin/apolipoprotein J, a functional homologue to the small heat shock proteins, by oxidative stress in ageing and age-related diseases.

Free Radic Res 2006 Dec;40(12):1324-34

Laboratory of Molecular & Cellular Ageing, Institute of Biological Research & Biotechnology, National Hellenic Research Foundation, Athens, Greece.

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http://www.tandfonline.com/doi/full/10.1080/1071576060090231
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http://dx.doi.org/10.1080/10715760600902310DOI Listing
December 2006

Comparative effects of hypoxia on normal and immortalized human diploid fibroblasts.

Anticancer Res 2006 May-Jun;26(3A):2165-8

Laboratory of Molecular and Cellular Aging, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, 48 Vas. Constantinou Ave., Athens 11635, Greece.

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August 2006

Proteasome response to interferon-gamma is altered in senescent human fibroblasts.

FEBS Lett 2006 Jul 21;580(16):3989-94. Epub 2006 Jun 21.

Department of Biochemistry, University of Bristol, School of Medical Sciences, Bristol, BS8 1TD, United Kingdom.

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http://doi.wiley.com/10.1016/j.febslet.2006.06.029
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http://dx.doi.org/10.1016/j.febslet.2006.06.029DOI Listing
July 2006

The genetics of human longevity.

Ann N Y Acad Sci 2006 May;1067:252-63

CIG - Centro Interdipartimentale L. Galvani, University of Bologna, Italy.

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http://dx.doi.org/10.1196/annals.1354.033DOI Listing
May 2006

Reduced expression levels of the senescence biomarker clusterin/apolipoprotein j in lymphocytes from healthy centenarians.

Ann N Y Acad Sci 2006 May;1067:294-300

Laboratory of Molecular & Cellular Ageing, Institute of Biological Research & Biotechnology, National Hellenic Research Foundation, Athens, Greece.

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http://dx.doi.org/10.1196/annals.1354.039DOI Listing
May 2006

Identification of differentially expressed proteins in senescent human embryonic fibroblasts.

Mech Ageing Dev 2006 Jan 5;127(1):88-92. Epub 2005 Oct 5.

Laboratory of Molecular & Cellular Ageing, Institute of Biological Research & Biotechnology, National Hellenic Research Foundation, 48 Vas. Constantinou Ave., Athens 11635, Greece.

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http://dx.doi.org/10.1016/j.mad.2005.08.009DOI Listing
January 2006

Bcl-2 but not clusterin/apolipoprotein J protected human diploid fibroblasts and immortalized keratinocytes from ceramide-induced apoptosis: role of p53 in the ceramide response.

Arch Biochem Biophys 2006 Jan 2;445(1):184-95. Epub 2005 Nov 2.

Cell and Molecular Physiology Unit, Laboratory of Experimental Physiology, University of Ioannina Medical School, 45 110 Ioannina, Greece.

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http://dx.doi.org/10.1016/j.abb.2005.10.006DOI Listing
January 2006

Proteasome dysfunction in mammalian aging: steps and factors involved.

Exp Gerontol 2005 Dec 24;40(12):931-8. Epub 2005 Oct 24.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vas. Constantinou Ave., Athens 116 35, Greece.

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http://linkinghub.elsevier.com/retrieve/pii/S053155650500205
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http://dx.doi.org/10.1016/j.exger.2005.09.004DOI Listing
December 2005

Cloning of differentially expressed genes in skin fibroblasts from centenarians.

Biogerontology 2004 ;5(6):401-9

Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, 48 Vas.Constantinou Ave., Athens 116 35, Greece.

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http://dx.doi.org/10.1007/s10522-004-3188-1DOI Listing
April 2005

Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates.

J Biol Chem 2005 Mar 20;280(12):11840-50. Epub 2005 Jan 20.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vasileos Constantinou Avenue, Athens 116 35, Greece.

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http://www.jbc.org/cgi/doi/10.1074/jbc.M413007200
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http://dx.doi.org/10.1074/jbc.M413007200DOI Listing
March 2005

Differential effects of clusterin/apolipoprotein J on cellular growth and survival.

Free Radic Biol Med 2005 Feb;38(4):436-49

Laboratory of Molecular & Cellular Aging, Institute of Biological Research & Biotechnology, National Hellenic Research Foundation, 48 Vas. Constantinou Ave., Athens 11635, Greece.

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http://dx.doi.org/10.1016/j.freeradbiomed.2004.10.038DOI Listing
February 2005

Ectopic expression of clusterin/apolipoprotein J or Bcl-2 decreases the sensitivity of HaCaT cells to toxic effects of ropivacaine.

Cell Res 2004 Oct;14(5):415-22

Laboratory of Experimental Physiology, University of Ioannina Medical School, 45110 Ioannina, Greece.

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http://dx.doi.org/10.1038/sj.cr.7290242DOI Listing
October 2004

Proteasome inhibition induces a senescence-like phenotype in primary human fibroblasts cultures.

Biogerontology 2004 ;5(1):55-61

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vas. Constantinou Ave., Athens 116 35, Greece.

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http://dx.doi.org/10.1023/b:bgen.0000017687.55667.42DOI Listing
August 2004

Alterations of senescence biomarkers in human cells by exposure to CrVI in vivo and in vitro.

Exp Gerontol 2004 Jul;39(7):1079-87

National Hellenic Research Foundation, Laboratory of Molecular and Cellular Ageing, Institute of Biological Research and Biotechnology, 48 Vas. Constantinou Avenue, Athens 11635, Greece.

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http://dx.doi.org/10.1016/j.exger.2004.03.039DOI Listing
July 2004

Functional analysis of clusterin/apolipoprotein J in cellular death induced by severe genotoxic stress.

Ann N Y Acad Sci 2004 Jun;1019:206-10

Laboratory of Molecular and Cellular Aging, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens 11635, Greece.

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http://dx.doi.org/10.1196/annals.1297.033DOI Listing
June 2004

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

J Biol Chem 2003 Jul 7;278(30):28026-37. Epub 2003 May 7.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vas. Constantinou Ave., Athens 11635, Greece.

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http://dx.doi.org/10.1074/jbc.M301048200DOI Listing
July 2003

Serum levels of the senescence biomarker clusterin/apolipoprotein J increase significantly in diabetes type II and during development of coronary heart disease or at myocardial infarction.

Exp Gerontol 2002 Oct-Nov;37(10-11):1175-87

Laboratory of Molecular and Cellular Ageing, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, 48 Vas. Constantinou Avenue, Athens 11635, Greece.

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http://dx.doi.org/10.1016/s0531-5565(02)00139-0DOI Listing
April 2003

Protein degradation during aging: the lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems.

Biogerontology 2002 ;3(1-2):121-3

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, Athens, Greece.

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http://dx.doi.org/10.1023/a:1015236203379DOI Listing
November 2002

Clusterin/apolipoprotein J in human aging and cancer.

Int J Biochem Cell Biol 2002 Nov;34(11):1430-48

Laboratory of Molecular & Cellular Aging, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, 48 Vas Constantinou Avenue, Athens 11635, Greece.

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http://dx.doi.org/10.1016/s1357-2725(02)00041-9DOI Listing
November 2002

Identification of a candidate tumor-suppressor gene specifically activated during Ras-induced senescence.

Exp Cell Res 2002 Feb;273(2):127-37

Department of Immunology and Oncology, Spanish National Center of Biotechnology (CSIC), Campus de Cantoblanco, Madrid E-28049, Spain.

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http://dx.doi.org/10.1006/excr.2001.5434DOI Listing
February 2002

Cloning approaches for identifying aging and longevity-related genes in mammals.

ScientificWorldJournal 2002 Feb 22;2:483-91. Epub 2002 Feb 22.

National Hellenic Research Foundation, Institute of Biological Research and Biotechnology, 48 Vas. Constantinou Ave., Athens 11635, Greece.

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http://www.hindawi.com/journals/tswj/2002/878390/abs/
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http://dx.doi.org/10.1100/tsw.2002.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009395PMC
February 2002