Publications by authors named "Efsevia Vakiani"

88Publications

Cdc42 Mediates Cancer Cell Chemotaxis in Perineural Invasion.

Mol Cancer Res 2020 06 21;18(6):913-925. Epub 2020 Feb 21.

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1541-7786.MCR-19-0726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272295PMC
June 2020

Distinct histomorphological features are associated with IDH1 mutation in intrahepatic cholangiocarcinoma.

Hum Pathol 2019 09 21;91:19-25. Epub 2019 May 21.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065 USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2019.05.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744317PMC
September 2019

Somatic HNF1A mutations in the malignant transformation of hepatocellular adenomas: a retrospective analysis of data from MSK-IMPACT and TCGA.

Hum Pathol 2019 01 17;83:1-6. Epub 2018 Aug 17.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Pathology, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365190PMC
January 2019

Clinical Sequencing Defines the Genomic Landscape of Metastatic Colorectal Cancer.

Cancer Cell 2018 01;33(1):125-136.e3

Marie-Josée and Henry R. Kravis Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Departments of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765991PMC
January 2018

Molecular Testing of Colorectal Cancer in the Modern Era: What Are We Doing and Why?

Authors:
Efsevia Vakiani

Surg Pathol Clin 2017 Dec 5;10(4):1009-1020. Epub 2017 Oct 5.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.path.2017.07.013DOI Listing
December 2017

Kras mutation is a marker of worse oncologic outcomes after percutaneous radiofrequency ablation of colorectal liver metastases.

Oncotarget 2017 Sep 2;8(39):66117-66127. Epub 2017 Aug 2.

Section of Interventional Radiology, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.18632/oncotarget.19806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630397PMC
September 2017

Logarithmic expansion of LGR5 cells in human colorectal cancer.

Cell Signal 2018 Jan 25;42:97-105. Epub 2017 Sep 25.

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2017.09.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766032PMC
January 2018

Erratum: Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 08;23(8):1004

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http://dx.doi.org/10.1038/nm0817-1004cDOI Listing
August 2017

A Subset of Malignant Mesotheliomas in Young Adults Are Associated With Recurrent EWSR1/FUS-ATF1 Fusions.

Am J Surg Pathol 2017 Jul;41(7):980-988

*Department of Pathology §Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY †Department of Pathology, Quebec Heart and Lung Institute, Quebec, QC, Canada ‡Department of Pathology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5468482PMC
July 2017

Mutational landscape of metastatic cancer revealed from prospective clinical sequencing of 10,000 patients.

Authors:
Ahmet Zehir Ryma Benayed Ronak H Shah Aijazuddin Syed Sumit Middha Hyunjae R Kim Preethi Srinivasan Jianjiong Gao Debyani Chakravarty Sean M Devlin Matthew D Hellmann David A Barron Alison M Schram Meera Hameed Snjezana Dogan Dara S Ross Jaclyn F Hechtman Deborah F DeLair JinJuan Yao Diana L Mandelker Donavan T Cheng Raghu Chandramohan Abhinita S Mohanty Ryan N Ptashkin Gowtham Jayakumaran Meera Prasad Mustafa H Syed Anoop Balakrishnan Rema Zhen Y Liu Khedoudja Nafa Laetitia Borsu Justyna Sadowska Jacklyn Casanova Ruben Bacares Iwona J Kiecka Anna Razumova Julie B Son Lisa Stewart Tessara Baldi Kerry A Mullaney Hikmat Al-Ahmadie Efsevia Vakiani Adam A Abeshouse Alexander V Penson Philip Jonsson Niedzica Camacho Matthew T Chang Helen H Won Benjamin E Gross Ritika Kundra Zachary J Heins Hsiao-Wei Chen Sarah Phillips Hongxin Zhang Jiaojiao Wang Angelica Ochoa Jonathan Wills Michael Eubank Stacy B Thomas Stuart M Gardos Dalicia N Reales Jesse Galle Robert Durany Roy Cambria Wassim Abida Andrea Cercek Darren R Feldman Mrinal M Gounder A Ari Hakimi James J Harding Gopa Iyer Yelena Y Janjigian Emmet J Jordan Ciara M Kelly Maeve A Lowery Luc G T Morris Antonio M Omuro Nitya Raj Pedram Razavi Alexander N Shoushtari Neerav Shukla Tara E Soumerai Anna M Varghese Rona Yaeger Jonathan Coleman Bernard Bochner Gregory J Riely Leonard B Saltz Howard I Scher Paul J Sabbatini Mark E Robson David S Klimstra Barry S Taylor Jose Baselga Nikolaus Schultz David M Hyman Maria E Arcila David B Solit Marc Ladanyi Michael F Berger

Nat Med 2017 Jun 8;23(6):703-713. Epub 2017 May 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, USA.

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http://www.nature.com/doifinder/10.1038/nm.4333
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http://dx.doi.org/10.1038/nm.4333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461196PMC
June 2017

Clinicopathologic Features of Colorectal Carcinoma in HIV-Positive Patients.

Cancer Epidemiol Biomarkers Prev 2016 07 13;25(7):1098-104. Epub 2016 May 13.

Division of General Internal Medicine, Mount Sinai School of Medicine, New York, New York.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-1179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942127PMC
July 2016

ARID1A expression in early stage colorectal adenocarcinoma: an exploration of its prognostic significance.

Hum Pathol 2016 07 2;53:97-104. Epub 2016 Mar 2.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994515PMC
July 2016

Tumor evolution and intratumor heterogeneity in colorectal carcinoma: insights from comparative genomic profiling of primary tumors and matched metastases.

J Gastrointest Oncol 2015 Dec;6(6):668-75

1 Human Oncology and Pathogenesis Program, 2 Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.3978/j.issn.2078-6891.2015.083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671856PMC
December 2015

Identification of Targetable Kinase Alterations in Patients with Colorectal Carcinoma That are Preferentially Associated with Wild-Type RAS/RAF.

Mol Cancer Res 2016 Mar 11;14(3):296-301. Epub 2015 Dec 11.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York. Human Oncology & Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0392-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972456PMC
March 2016

Phase II Trial of Sorafenib in Patients with Chemotherapy Refractory Metastatic Esophageal and Gastroesophageal (GE) Junction Cancer.

PLoS One 2015 14;10(8):e0134731. Epub 2015 Aug 14.

Gastrointestinal Oncology Service, Division of Solid Tumor Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134731PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537304PMC
May 2016

HER2 testing in gastric and gastroesophageal adenocarcinomas.

Authors:
Efsevia Vakiani

Adv Anat Pathol 2015 May;22(3):194-201

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/PAP.0000000000000067DOI Listing
May 2015

Corrigendum to "Asymptomatic Liver Abscesses Mimicking Metastases in Patients after Whipple Surgery: Infectious Complications following Percutaneous Biopsy-A Report of Two Cases".

Case Reports Hepatol 2015 3;2015:783506. Epub 2015 Feb 3.

Division of Interventional Radiology, Department of Radiology, Memorial Sloan-Kettering Cancer Center (MSKCC), 1275 York Avenue, M276C, New York, NY 10065, USA.

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http://dx.doi.org/10.1155/2015/783506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332762PMC
March 2015

Immunohistochemical detection of the BRAF V600E mutant protein in colorectal neoplasms.

Appl Immunohistochem Mol Morphol 2015 Jul;23(6):438-43

Departments of *Pathology †Medicine ‡Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/PAI.0000000000000116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994705PMC
July 2015

Ganetespib, a novel Hsp90 inhibitor in patients with KRAS mutated and wild type, refractory metastatic colorectal cancer.

Clin Colorectal Cancer 2014 Dec 21;13(4):207-12. Epub 2014 Sep 21.

Gastrointestinal Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1016/j.clcc.2014.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5489410PMC
December 2014

Mismatch repair deficient-crypts in non-neoplastic colonic mucosa in Lynch syndrome: insights from an illustrative case.

Fam Cancer 2015 Mar;14(1):61-8

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, 10065, USA,

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http://dx.doi.org/10.1007/s10689-014-9751-2DOI Listing
March 2015

Poorly differentiated neuroendocrine carcinomas of the pancreas: a clinicopathologic analysis of 44 cases.

Am J Surg Pathol 2014 Apr;38(4):437-47

Departments of *Pathology ***Surgery †††Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY †Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center ‡‡‡Department of Surgery, Johns Hopkins University, Baltimore, MD ‡Department of Pathology, Emory University, Atlanta, GA §Department of Pathology, Penn State Hershey MC, Hershey ∥Department of Pathology, University of Pittsburgh, Pittsburgh, PA **Department of Pathology, Ohio State University, Columbus ††Department of Pathology, Cleveland Clinic, Cleveland, OH ‡‡Department of Pathology, Mayo Clinic, Rochester, MN §§Department of Pathology, University of Michigan, Ann Arbor, MI ∥∥Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA ¶¶Department of Pathology, Indiana University, Indianapolis, IN ##Department of Pathology, Vanderbilt University, Nashville, TN §§§Department of Pathology, Massachusetts General Hospital, Boston, MA ¶Department of Pathology, Ospedale di Circolo, Varese, Italy #Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0000000000000169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977000PMC
April 2014

Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.

Cancer Discov 2013 Mar 28;3(3):294-307. Epub 2012 Dec 28.

Molecular Pathology Unit, Center for Cancer Research and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Charlestown 02129 , USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595397PMC
March 2013

Radiation impairs perineural invasion by modulating the nerve microenvironment.

PLoS One 2012 29;7(6):e39925. Epub 2012 Jun 29.

Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039925PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386941PMC
November 2012

A phase 2 study of the insulin-like growth factor-1 receptor inhibitor MK-0646 in patients with metastatic, well-differentiated neuroendocrine tumors.

Cancer 2012 Oct 21;118(19):4795-800. Epub 2012 Mar 21.

Department of Medicine, Division of Solid Tumors, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1002/cncr.27459DOI Listing
October 2012

Asymptomatic Liver Abscesses Mimicking Metastases in Patients after Whipple Surgery: Infectious Complications following Percutaneous Biopsy-A Report of Two Cases.

Case Reports Hepatol 2012 3;2012:817314. Epub 2012 Sep 3.

Division of Interventional Radiology, Department of Radiology, Memorial Sloan-Kettering Cancer Center (MSKCC), 1275 York Avenue, M276C, New York, NY 10065, USA.

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http://dx.doi.org/10.1155/2012/817314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4208445PMC
November 2014

KRAS and BRAF: drug targets and predictive biomarkers.

J Pathol 2011 Jan 28;223(2):219-29. Epub 2010 Oct 28.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://doi.wiley.com/10.1002/path.2796
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http://dx.doi.org/10.1002/path.2796DOI Listing
January 2011

Acinar cell cystadenoma of the pancreas in a 9-year-old boy.

J Pediatr Surg 2010 May;45(5):e7-9

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.jpedsurg.2010.02.043DOI Listing
May 2010

Collagenous sprue is not always associated with dismal outcomes: a clinicopathological study of 19 patients.

Mod Pathol 2010 Jan 23;23(1):12-26. Epub 2009 Oct 23.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/modpathol.2009.151DOI Listing
January 2010

Pathologic features and biologic importance of colorectal serrated polyps.

Adv Anat Pathol 2009 Mar;16(2):79-91

Department of Pathology, Memorial Sloan-Kettering Cancer Center, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10065, USA.

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http://dx.doi.org/10.1097/PAP.0b013e31819923b3DOI Listing
March 2009

Acinar cell carcinoma of the pancreas metastatic to the ovary: a report of 4 cases.

Am J Surg Pathol 2008 Oct;32(10):1540-5

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1097/PAS.0b013e31817a8ebbDOI Listing
October 2008

The spectrum of B-cell non-Hodgkin lymphomas with dual IgH-BCL2 and BCL6 translocations.

Am J Clin Pathol 2008 Aug;130(2):193-201

Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1309/ELPKF130Q0MCMWU8DOI Listing
August 2008

Neoadjuvant chemotherapy and radiation for patients with locally unresectable pancreatic adenocarcinoma: feasibility, efficacy, and survival.

J Gastrointest Surg 2008 Jan 5;12(1):91-100. Epub 2007 Sep 5.

Department of Surgery, Columbia University College of Physicians and Surgeons, 630 West 168th St., New York, NY 10032, USA.

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http://link.springer.com/10.1007/s11605-007-0296-7
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http://dx.doi.org/10.1007/s11605-007-0296-7DOI Listing
January 2008

Hepatitis C-associated granulomas after liver transplantation: morphologic spectrum and clinical implications.

Am J Clin Pathol 2007 Jan;127(1):128-34

Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA.

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https://academic.oup.com/ajcp/article-lookup/doi/10.1309/NN0
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http://dx.doi.org/10.1309/NN03WMD8V0GK6HFWDOI Listing
January 2007

Intrachromosomal rearrangement of chromosome 3q27: an under recognized mechanism of BCL6 translocation in B-cell non-Hodgkin lymphoma.

Hum Pathol 2006 Aug 21;37(8):1093-9. Epub 2006 Jun 21.

Department of Pathology, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.humpath.2006.03.016DOI Listing
August 2006

CD117 expression in diffuse large B-cell lymphomas: fact or fiction?

Pathol Int 2005 Nov;55(11):716-23

Department of Pathology, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1111/j.1440-1827.2005.01893.xDOI Listing
November 2005

T-Cell lymphoblastic lymphoma presenting as bilateral multinodular breast masses: a case report and review of the literature.

Am J Hematol 2005 Nov;80(3):216-22

Department of Pathology, Columbia Presbyterian Medical Center, 630 West 168th Street, New York, New York 10033, USA.

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http://dx.doi.org/10.1002/ajh.20448DOI Listing
November 2005

Successful bilateral lung transplantation for pulmonary fibrosis associated with the Hermansky-Pudlak syndrome.

J Heart Lung Transplant 2005 Oct;24(10):1697-9

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S105324980400618
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http://dx.doi.org/10.1016/j.healun.2004.11.015DOI Listing
October 2005