Publications by authors named "Edwin Kwan"

16Publications

Aganglionosis with the absence of hypertrophied nerve fibres predicts disease proximal to rectosigmoid colon.

Pediatr Surg Int 2016 Mar 2;32(3):221-6. Epub 2015 Nov 2.

The Children's Hospital at Westmead, Westmead, New South Wales, Australia.

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March 2016

One-dose vaccination associated with attenuated disease severity of adolescent and adult varicella cases in Beijing's Fengtai District.

Hum Vaccin Immunother 2014 ;10(8):2417-20

Department of Epidemiology and Biostatistics; School of Public Health; Capital Medical University; 2. Fengtai Center for Disease Control and Prevention; Beijing, China.

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July 2015

Pancreatic GLP-1 receptor activation is sufficient for incretin control of glucose metabolism in mice.

J Clin Invest 2012 Jan 19;122(1):388-402. Epub 2011 Dec 19.

Department of Medicine, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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January 2012

High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.

Am J Physiol Endocrinol Metab 2009 Jun 17;296(6):E1251-61. Epub 2009 Feb 17.

Dept. of Medicine, Mount Sinai Hospital, 60 Murray St., Lebovic Bldg, Rm. 5028, Toronto, ON, Canada M5T 3L9.

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June 2009

Rescuing the subprime meltdown in insulin exocytosis in diabetes.

Ann N Y Acad Sci 2009 Jan;1152:154-64

Department of Physiology, University of Toronto, Toronto, Ontario, Canada.

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January 2009

The RalA GTPase is a central regulator of insulin exocytosis from pancreatic islet beta cells.

J Biol Chem 2008 Jun 21;283(26):17939-45. Epub 2008 Apr 21.

Diabetes and Obesity Program, Garvan Institute of Medical Research, Sydney, NSW, Australia.

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June 2008

Munc18-1 is critical for plasma membrane localization of syntaxin1 but not of SNAP-25 in PC12 cells.

Mol Biol Cell 2008 Feb 12;19(2):722-34. Epub 2007 Dec 12.

Division of Fundamental Neurobiology, Toronto Western Research Institute, University Health Network, Toronto, Ontario, M5T 2S8, Canada.

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February 2008

SNAREing voltage-gated K+ and ATP-sensitive K+ channels: tuning beta-cell excitability with syntaxin-1A and other exocytotic proteins.

Endocr Rev 2007 Oct 18;28(6):653-63. Epub 2007 Sep 18.

Departmnet of Physiology, China Medical University, Taichung 40402, Taiwan.

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October 2007

Distinct in vivo roles of caspase-8 in beta-cells in physiological and diabetes models.

Diabetes 2007 Sep 11;56(9):2302-11. Epub 2007 Jun 11.

Department of Medical Biophysics, Ontario Cancer Institute, and the University of Toronto, Toronto, Ontario, Canada.

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September 2007

Munc13-1 deficiency reduces insulin secretion and causes abnormal glucose tolerance.

Diabetes 2006 May;55(5):1421-9

Department of Physiology, University of Toronto, Medical Sciences Building Rm. 7226, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.

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May 2006

Glucagon-like peptide 1 regulates sequential and compound exocytosis in pancreatic islet beta-cells.

Diabetes 2005 Sep;54(9):2734-43

University of Toronto, 1 Kings College Circle, Room 7226, Toronto, ON, Canada.

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September 2005

Disruption of pancreatic beta-cell lipid rafts modifies Kv2.1 channel gating and insulin exocytosis.

J Biol Chem 2004 Jun 8;279(23):24685-91. Epub 2004 Apr 8.

Departments of Medicine and Physiology, University of Toronto, Toronto, Ontario M5S 1A8,Canada.

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June 2004

Visualization of sequential exocytosis in rat pancreatic islet beta cells.

Biochem Biophys Res Commun 2002 Apr;292(4):980-6

Department of Medicine, University of Toronto, Toronto, Ontario, M5S 1A8, Canada.

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April 2002