Edwin Kamau

Edwin Kamau

UNVERIFIED PROFILE

Are you Edwin Kamau?   Register this Author

Register author
Edwin Kamau

Edwin Kamau

Publications by authors named "Edwin Kamau"

Are you Edwin Kamau?   Register this Author

55Publications

1594Reads

26Profile Views

Antimicrobial Activity of Clinically Isolated Bacterial Species Against .

Front Microbiol 2019 15;10:2977. Epub 2020 Jan 15.

Department of Microbiology and Immunology, F. Edward Hébert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2019.02977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975196PMC
January 2020

The prevalence and antifolate drug resistance profiles of Plasmodium falciparum in study participants randomized to discontinue or continue cotrimoxazole prophylaxis.

PLoS Negl Trop Dis 2019 03 21;13(3):e0007223. Epub 2019 Mar 21.

Department of Emerging and Infectious Diseases (DEID), United States Army Medical Research Directorate-Africa (USAMRD-A), Kenya Medical Research Institute (KEMRI) Kisumu, Kenya.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pntd.0007223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445470PMC
March 2019

Sequential trafficking of Env and Gag to HIV-1 T cell virological synapses revealed by live imaging.

Retrovirology 2019 01 15;16(1). Epub 2019 Jan 15.

Department of Medicine, Division of Infectious Diseases, Immunology Institute, Mount Sinai School of Medicine, New York, NY, 10029, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12977-019-0464-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334456PMC
January 2019

Computational-guided determination of the functional role of 447-52D long CDRH3.

Protein Eng Des Sel 2018 12;31(12):479-487

Department of Biochemistry and Molecular Pharmacology, NYU School of Medicine, New York NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/protein/gzz007DOI Listing
December 2018

Selective sweeps and genetic lineages of Plasmodium falciparum multi-drug resistance (pfmdr1) gene in Kenya.

Malar J 2018 Oct 30;17(1):398. Epub 2018 Oct 30.

Global Emerging Infections Surveillance Program, United States Army Medical Research Directorate-Africa, Kenya Medical Research Institute, P.O. Box 54, 40100, Kisumu, Kenya.

View Article

Download full-text PDF

Source
https://malariajournal.biomedcentral.com/articles/10.1186/s1
Publisher Site
http://dx.doi.org/10.1186/s12936-018-2534-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208105PMC
October 2018

Polymorphisms in the K13 Gene in from Different Malaria Transmission Areas of Kenya.

Am J Trop Med Hyg 2018 05 22;98(5):1360-1366. Epub 2018 Mar 22.

Kenya Medical Research Institute/United States Army Medical Research Directorate-Kenya, Kisumu, Kenya.

View Article

Download full-text PDF

Source
http://www.ajtmh.org/content/journals/10.4269/ajtmh.17-0505
Publisher Site
http://dx.doi.org/10.4269/ajtmh.17-0505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5953360PMC
May 2018

Genetically Determined Response to Artemisinin Treatment in Western Kenyan Plasmodium falciparum Parasites.

PLoS One 2016 9;11(9):e0162524. Epub 2016 Sep 9.

Department of Emerging and Infectious Diseases, United States Army Medical Research Directorate-Kenya, Kenya Medical Research Institute (KEMRI)/Walter Reed Project, Kisumu, Kenya.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162524PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017781PMC
August 2017

The Genotypic and Phenotypic Stability of Plasmodium falciparum Field Isolates in Continuous In Vitro Culture.

PLoS One 2016 11;11(1):e0143565. Epub 2016 Jan 11.

Department of Emerging Infectious Diseases-Global Emerging Infections Surveillance and Response System (DEID-GEIS) Program, United States Army Medical Research Directorate-Kenya (USAMRD-K), Kenya Medical Research Institute (KEMRI)-Walter Reed Project, Kisumu, Kenya.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0143565PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713440PMC
June 2016

Genetic variability and population structure of Plasmodium falciparum parasite populations from different malaria ecological regions of Kenya.

Infect Genet Evol 2016 Apr 22;39:372-380. Epub 2015 Oct 22.

Department of Emerging and Infectious Diseases (DEID), United States Army Medical Research Directorate-Kenya (USAMRD-K), Kenya Medical Research Institute (KEMRI)/Walter Reed Project (WRP), Kisumu, Kenya. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15671348153001
Publisher Site
http://dx.doi.org/10.1016/j.meegid.2015.10.013DOI Listing
April 2016

Assessment of the Worldwide Antimalarial Resistance Network Standardized Procedure for In Vitro Malaria Drug Sensitivity Testing Using SYBR Green Assay for Field Samples with Various Initial Parasitemia Levels.

Antimicrob Agents Chemother 2016 Apr 25;60(4):2417-24. Epub 2016 Mar 25.

Department of Emerging Infectious Diseases-Global Emerging Infections Surveillance and Response System (DEID-GEIS) Program, U.S. Army Medical Research Directorate-Kenya (USAMRD-K), Kenya Medical Research Institute (KEMRI)-Walter Reed Project, Kisumu, Kenya

View Article

Download full-text PDF

Source
http://aac.asm.org/content/early/2016/02/02/AAC.00527-15.ful
Web Search
http://aac.asm.org/lookup/doi/10.1128/AAC.00527-15
Publisher Site
http://dx.doi.org/10.1128/AAC.00527-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808143PMC
April 2016

Temporal trends in prevalence of Plasmodium falciparum molecular markers selected for by artemether-lumefantrine treatment in pre-ACT and post-ACT parasites in western Kenya.

Int J Parasitol Drugs Drug Resist 2015 Dec 29;5(3):92-9. Epub 2015 Jun 29.

Department of Emerging Infectious Diseases, United States Army Medical Research Unit-Kenya/Kenya Medical Research Institute, Kisumu, Kenya.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijpddr.2015.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501530PMC
December 2015

K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa.

J Infect Dis 2015 Apr 2;211(8):1352-5. Epub 2014 Nov 2.

Wellcome Trust Sanger Institute, Hinxton Malaria Research and Training Centre, Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Science, Techniques and Technologies of Bamako, Mali.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/infdis/jiu608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827505PMC
April 2015

Antiplasmodial compounds from the stem bark of Neoboutonia macrocalyx pax.

J Ethnopharmacol 2015 Mar 19;162:317-22. Epub 2014 Dec 19.

Centre de Recherche de Gif, Institut de Chimie des Substances Naturelles, CNRS-Avenue de la Terresse, 91198 Gif-sur-Yvette, France. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03788741140089
Publisher Site
http://dx.doi.org/10.1016/j.jep.2014.12.018DOI Listing
March 2015

Molecular characterization of the cytochrome b gene and in vitro atovaquone susceptibility of Plasmodium falciparum isolates from Kenya.

Antimicrob Agents Chemother 2015 Mar 12;59(3):1818-21. Epub 2015 Jan 12.

Department of Emerging Infectious Diseases-Global Emerging Infections Surveillance and Response System (DEID-GEIS) Program, U.S. Army Medical Research Unit-Kenya (USAMRU-K), Kenya Medical Research Institute (KEMRI)-Walter Reed Project, Kisumu, Kenya

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.03956-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4325819PMC
March 2015

Analysis of major genome loci underlying artemisinin resistance and pfmdr1 copy number in pre- and post-ACTs in western Kenya.

Sci Rep 2015 Feb 6;5:8308. Epub 2015 Feb 6.

Department of Emerging Infectious Diseases-Global Emerging Infections Surveillance and Response System (DEID-GEIS) Program, United States Army Medical Research Unit-Kenya (USAMRU-K), Kenya Medical Research Institute (KEMRI)-Walter Reed Project, Kisumu, Kenya.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep08308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4319159PMC
February 2015

Five-year tracking of Plasmodium falciparum allele frequencies in a holoendemic area with indistinct seasonal transitions.

J Multidiscip Healthc 2014 6;7:515-23. Epub 2014 Nov 6.

Global Emerging Infections Surveillance Program, United States Army Medical Research Unit-Kenya, Kenya Medical Research Institute, Walter Reed Project, Kisumu and Nairobi, Kenya.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2147/JMDH.S67252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227620PMC
November 2014

Reduced in vitro doxycycline susceptibility in plasmodium falciparum field isolates from Kenya is associated with PfTetQ KYNNNN sequence polymorphism.

Antimicrob Agents Chemother 2014 Oct 28;58(10):5894-9. Epub 2014 Jul 28.

Department of Emerging Infectious Diseases-Global Emerging Infections Surveillance and Response System (DEID-GEIS) Program, United States Army Medical Research Unit-Kenya (USAMRU-K), Kenya Medical Research Institute (KEMRI)-Walter Reed Project, Kisumu, Kenya

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.02788-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187988PMC
October 2014

Monitoring parasite diversity for malaria elimination in sub-Saharan Africa.

Science 2014 Sep;345(6202):1297-8

Malaria Research and Training Centre (MRTC), Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, University of Sciences, Techniques and Technologies of Bamako, Bamako, Mali. Wellcome Trust Sanger Institute, Hinxton, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1259423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541720PMC
September 2014

Single genome analysis reveals genetic characteristics of Neuroadaptation across HIV-1 envelope.

Retrovirology 2014 Aug 15;11:65. Epub 2014 Aug 15.

Aaron Diamond AIDS Research Center, an affiliate of the Rockefeller University, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12977-014-0065-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4145222PMC
August 2014

Trends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012.

Malar J 2014 Jul 2;13:250. Epub 2014 Jul 2.

Global Emerging Infections Surveillance (GEIS) Program, United States Army Medical Research Unit-Kenya (USAMRU-K), Kenya Medical Research Institute (KEMRI) - Walter Reed Project, Kisumu and Nairobi, Kenya.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2875-13-250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094641PMC
July 2014

Longitudinal study on Plasmodium falciparum gametocyte carriage following artemether-lumefantrine administration in a cohort of children aged 12-47 months living in Western Kenya, a high transmission area.

Malar J 2014 Jul 9;13:265. Epub 2014 Jul 9.

Department of Emerging Infectious Diseases-Global Emerging Infections Surveillance and Response System (DEID-GEIS) Program, United States Army Medical Research Unit-Kenya (USAMRU-K), Kenya Medical Research Institute (KEMRI)-Walter Reed Project, P,O, Box 54, Kisumu, 40100, Kenya.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2875-13-265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4105514PMC
July 2014

Measurement of parasitological data by quantitative real-time PCR from controlled human malaria infection trials at the Walter Reed Army Institute of Research.

Malar J 2014 Jul 28;13:288. Epub 2014 Jul 28.

Military Malaria Research Program, Malaria Vaccine Branch, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2875-13-288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4128310PMC
July 2014

Multiplex qPCR for detection and absolute quantification of malaria.

PLoS One 2013 29;8(8):e71539. Epub 2013 Aug 29.

Military Malaria Research Program, Malaria Vaccine Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071539PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756973PMC
April 2014

Sample-ready multiplex qPCR assay for detection of malaria.

Malar J 2014 Apr 25;13:158. Epub 2014 Apr 25.

Walter Reed Army Institute of Research, Military Malaria Research Program, Malaria Vaccine Branch, 503 Robert Grant Ave, Silver Spring, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2875-13-158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4026594PMC
April 2014

Phenotypic characterization of Plasmodium berghei responsive CD8+ T cells after immunization with live sporozoites under chloroquine cover.

Malar J 2014 Mar 12;13:92. Epub 2014 Mar 12.

Military Malaria Research Program, Malaria Vaccine Branch, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2875-13-92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008132PMC
March 2014

Comparative evaluation of published real-time PCR assays for the detection of malaria following MIQE guidelines.

Malar J 2013 Aug 8;12:277. Epub 2013 Aug 8.

Military Malaria Research Program, Malaria Vaccine Branch, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2875-12-277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750446PMC
August 2013

A focused small-molecule screen identifies 14 compounds with distinct effects on Toxoplasma gondii.

Antimicrob Agents Chemother 2012 Nov 20;56(11):5581-90. Epub 2012 Aug 20.

University of Pittsburgh, Department of Biological Sciences, Pittsburgh, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.00868-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486605PMC
November 2012

Development of a TaqMan Allelic Discrimination assay for detection of single nucleotides polymorphisms associated with anti-malarial drug resistance.

Malar J 2012 Jan 20;11:23. Epub 2012 Jan 20.

Military Malaria Research Program, Malaria Vaccine Branch, Department of Molecular Diagnostics and Genomic Studies, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, 20 Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1475-2875-11-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273427PMC
January 2012

Expression of yeast high mobility group protein HMO1 is regulated by TOR signaling.

Gene 2011 Dec 5;489(1):55-62. Epub 2011 Sep 5.

Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gene.2011.08.017DOI Listing
December 2011

A novel benzodioxole-containing inhibitor of Toxoplasma gondii growth alters the parasite cell cycle.

Antimicrob Agents Chemother 2011 Dec 26;55(12):5438-51. Epub 2011 Sep 26.

Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.00455-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232785PMC
December 2011

Development of a highly sensitive genus-specific quantitative reverse transcriptase real-time PCR assay for detection and quantitation of plasmodium by amplifying RNA and DNA of the 18S rRNA genes.

J Clin Microbiol 2011 Aug 8;49(8):2946-53. Epub 2011 Jun 8.

Division of Malaria Vaccine Development, Center for Molecular Diagnostics and Genomic Studies, Walter Reed Army Institute of Research, 503 Robert Grant Ave., Silver Spring, MD, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/JCM.00276-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147742PMC
August 2011

The deviation of liver dose in real patients for thoracic computed tomography scans: a new approach to individual dosimetry with methods of radiotherapy treatment planning.

Health Phys 2011 Jul;101(1):79-83

Institute for Radiology and Academy of Radiation Protection, Klinikum Links der Weser, Bremen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/HP.0b013e31820be7a5DOI Listing
July 2011

Interactions between N- and C-terminal domains of the Saccharomyces cerevisiae high-mobility group protein HMO1 are required for DNA bending.

Biochemistry 2006 Mar;45(11):3635-45

Department of Biological Sciences, Louisiana State University, Baton Rouge, Louisiana 70803, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi0522798DOI Listing
March 2006

Surface salt bridges modulate the DNA site size of bacterial histone-like HU proteins.

Biochem J 2005 Aug;390(Pt 1):49-55

Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20050274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184562PMC
August 2005

The Saccharomyces cerevisiae high mobility group box protein HMO1 contains two functional DNA binding domains.

J Biol Chem 2004 Dec 25;279(53):55234-40. Epub 2004 Oct 25.

Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M409459200DOI Listing
December 2004

Fluoroquinolone-dependent DNA supercoiling by Vaccinia topoisomerase I.

J Mol Biol 2004 Sep;342(2):479-87

Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmb.2004.06.082DOI Listing
September 2004