Edwin J C G van den Oord

Edwin J C G van den Oord

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Publications by authors named "Edwin J C G van den Oord"

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Independent Methylome-Wide Association Studies of Schizophrenia Detect Consistent Case-Control Differences.

Schizophr Bull 2019 Jun 5. Epub 2019 Jun 5.

Center for Biomarker Research and Precision Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, VA.

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http://dx.doi.org/10.1093/schbul/sbz056DOI Listing
June 2019

Successes and Challenges in Precision Medicine in Psychiatry.

JAMA Psychiatry 2018 Dec;75(12):1269-1270

Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond.

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http://dx.doi.org/10.1001/jamapsychiatry.2018.2897DOI Listing
December 2018

Association of Childhood Trauma Exposure With Adult Psychiatric Disorders and Functional Outcomes.

JAMA Netw Open 2018 Nov 2;1(7):e184493. Epub 2018 Nov 2.

Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1001/jamanetworkopen.2018.4493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324370PMC
November 2018

Epigenetic Aging in Major Depressive Disorder.

Am J Psychiatry 2018 08 16;175(8):774-782. Epub 2018 Apr 16.

From the Department of Psychiatry, VU University Medical Center, Amsterdam Neuroscience, GGZ inGeest, the Amsterdam Public Health Research Institute, Amsterdam; the Center for Biomarker Research and Precision Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond; the Molecular Psychiatry Laboratory, Florey Department of Neuroscience and Mental Health, Melbourne, Australia; and the Centre for Mental Health, Faculty of Health, Arts, and Design, Swinburne University, Hawthorne, Australia.

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http://dx.doi.org/10.1176/appi.ajp.2018.17060595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094380PMC
August 2018

Methyl-CpG-Binding Domain Sequencing: MBD-seq.

Methods Mol Biol 2018 ;1708:171-189

Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, P. O. Box 980533, Richmond, VA, 23298, USA.

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http://dx.doi.org/10.1007/978-1-4939-7481-8_10DOI Listing
July 2018

RaMWAS: fast methylome-wide association study pipeline for enrichment platforms.

Bioinformatics 2018 07;34(13):2283-2285

Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022807PMC
July 2018

A Whole Methylome CpG-SNP Association Study of Psychosis in Blood and Brain Tissue.

Schizophr Bull 2016 07 9;42(4):1018-26. Epub 2015 Dec 9.

Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, VA;

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http://dx.doi.org/10.1093/schbul/sbv182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4903046PMC
July 2016

Evaluation of Methyl-Binding Domain Based Enrichment Approaches Revisited.

PLoS One 2015 15;10(7):e0132205. Epub 2015 Jul 15.

Center for Biomarker Research and Precision Medicine, Virginia Commonwealth University, Richmond, VA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132205PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4503759PMC
April 2016

Candidate gene methylation studies are at high risk of erroneous conclusions.

Epigenomics 2015 ;7(1):13-5

Center for Biomarker Research & Personalized Medicine, Virginia Common-wealth University, PO Box 980533, Richmond, VA 23298, USA.

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http://dx.doi.org/10.2217/epi.14.70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503464PMC
September 2015

Could monitoring methylation markers aid the management of schizophrenia?

Biomark Med 2014 ;8(5):607-11

Center for Biomarker Research & Personalized Medicine, Virginia Commonwealth University, VA 23298, USA.

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https://www.futuremedicine.com/doi/10.2217/bmm.14.44
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http://dx.doi.org/10.2217/bmm.14.44DOI Listing
August 2015

Refinement of schizophrenia GWAS loci using methylome-wide association data.

Hum Genet 2015 Jan 7;134(1):77-87. Epub 2014 Oct 7.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, McGuire Hall, Room 219, P. O. Box 980533, Richmond, VA, 23298-0581, USA,

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http://dx.doi.org/10.1007/s00439-014-1494-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282961PMC
January 2015

Family-based replication study of schizophrenia genes.

JAMA Psychiatry 2014 Oct;71(10):1195-6

Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, Richmond.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.375DOI Listing
October 2014

Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles.

Nat Commun 2014 Sep 4;5:4757. Epub 2014 Sep 4.

1] Department of Psychiatry, University of North Carolina, Chapel Hill, North Carolina 27599, USA [2] Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA [3] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-171 77 Stockholm, Sweden [4].

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http://dx.doi.org/10.1038/ncomms5757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155508PMC
September 2014

Genotype-based ancestral background consistently predicts efficacy and side effects across treatments in CATIE and STAR*D.

PLoS One 2013 6;8(2):e55239. Epub 2013 Feb 6.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055239PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566192PMC
December 2013

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.

Authors:
S Hong Lee Stephan Ripke Benjamin M Neale Stephen V Faraone Shaun M Purcell Roy H Perlis Bryan J Mowry Anita Thapar Michael E Goddard John S Witte Devin Absher Ingrid Agartz Huda Akil Farooq Amin Ole A Andreassen Adebayo Anjorin Richard Anney Verneri Anttila Dan E Arking Philip Asherson Maria H Azevedo Lena Backlund Judith A Badner Anthony J Bailey Tobias Banaschewski Jack D Barchas Michael R Barnes Thomas B Barrett Nicholas Bass Agatino Battaglia Michael Bauer Mònica Bayés Frank Bellivier Sarah E Bergen Wade Berrettini Catalina Betancur Thomas Bettecken Joseph Biederman Elisabeth B Binder Donald W Black Douglas H R Blackwood Cinnamon S Bloss Michael Boehnke Dorret I Boomsma Gerome Breen René Breuer Richard Bruggeman Paul Cormican Nancy G Buccola Jan K Buitelaar William E Bunney Joseph D Buxbaum William F Byerley Enda M Byrne Sian Caesar Wiepke Cahn Rita M Cantor Miguel Casas Aravinda Chakravarti Kimberly Chambert Khalid Choudhury Sven Cichon C Robert Cloninger David A Collier Edwin H Cook Hilary Coon Bru Cormand Aiden Corvin William H Coryell David W Craig Ian W Craig Jennifer Crosbie Michael L Cuccaro David Curtis Darina Czamara Susmita Datta Geraldine Dawson Richard Day Eco J De Geus Franziska Degenhardt Srdjan Djurovic Gary J Donohoe Alysa E Doyle Jubao Duan Frank Dudbridge Eftichia Duketis Richard P Ebstein Howard J Edenberg Josephine Elia Sean Ennis Bruno Etain Ayman Fanous Anne E Farmer I Nicol Ferrier Matthew Flickinger Eric Fombonne Tatiana Foroud Josef Frank Barbara Franke Christine Fraser Robert Freedman Nelson B Freimer Christine M Freitag Marion Friedl Louise Frisén Louise Gallagher Pablo V Gejman Lyudmila Georgieva Elliot S Gershon Daniel H Geschwind Ina Giegling Michael Gill Scott D Gordon Katherine Gordon-Smith Elaine K Green Tiffany A Greenwood Dorothy E Grice Magdalena Gross Detelina Grozeva Weihua Guan Hugh Gurling Lieuwe De Haan Jonathan L Haines Hakon Hakonarson Joachim Hallmayer Steven P Hamilton Marian L Hamshere Thomas F Hansen Annette M Hartmann Martin Hautzinger Andrew C Heath Anjali K Henders Stefan Herms Ian B Hickie Maria Hipolito Susanne Hoefels Peter A Holmans Florian Holsboer Witte J Hoogendijk Jouke-Jan Hottenga Christina M Hultman Vanessa Hus Andrés Ingason Marcus Ising Stéphane Jamain Edward G Jones Ian Jones Lisa Jones Jung-Ying Tzeng Anna K Kähler René S Kahn Radhika Kandaswamy Matthew C Keller James L Kennedy Elaine Kenny Lindsey Kent Yunjung Kim George K Kirov Sabine M Klauck Lambertus Klei James A Knowles Martin A Kohli Daniel L Koller Bettina Konte Ania Korszun Lydia Krabbendam Robert Krasucki Jonna Kuntsi Phoenix Kwan Mikael Landén Niklas Långström Mark Lathrop Jacob Lawrence William B Lawson Marion Leboyer David H Ledbetter Phil H Lee Todd Lencz Klaus-Peter Lesch Douglas F Levinson Cathryn M Lewis Jun Li Paul Lichtenstein Jeffrey A Lieberman Dan-Yu Lin Don H Linszen Chunyu Liu Falk W Lohoff Sandra K Loo Catherine Lord Jennifer K Lowe Susanne Lucae Donald J MacIntyre Pamela A F Madden Elena Maestrini Patrik K E Magnusson Pamela B Mahon Wolfgang Maier Anil K Malhotra Shrikant M Mane Christa L Martin Nicholas G Martin Manuel Mattheisen Keith Matthews Morten Mattingsdal Steven A McCarroll Kevin A McGhee James J McGough Patrick J McGrath Peter McGuffin Melvin G McInnis Andrew McIntosh Rebecca McKinney Alan W McLean Francis J McMahon William M McMahon Andrew McQuillin Helena Medeiros Sarah E Medland Sandra Meier Ingrid Melle Fan Meng Jobst Meyer Christel M Middeldorp Lefkos Middleton Vihra Milanova Ana Miranda Anthony P Monaco Grant W Montgomery Jennifer L Moran Daniel Moreno-De-Luca Gunnar Morken Derek W Morris Eric M Morrow Valentina Moskvina Pierandrea Muglia Thomas W Mühleisen Walter J Muir Bertram Müller-Myhsok Michael Murtha Richard M Myers Inez Myin-Germeys Michael C Neale Stan F Nelson Caroline M Nievergelt Ivan Nikolov Vishwajit Nimgaonkar Willem A Nolen Markus M Nöthen John I Nurnberger Evaristus A Nwulia Dale R Nyholt Colm O'Dushlaine Robert D Oades Ann Olincy Guiomar Oliveira Line Olsen Roel A Ophoff Urban Osby Michael J Owen Aarno Palotie Jeremy R Parr Andrew D Paterson Carlos N Pato Michele T Pato Brenda W Penninx Michele L Pergadia Margaret A Pericak-Vance Benjamin S Pickard Jonathan Pimm Joseph Piven Danielle Posthuma James B Potash Fritz Poustka Peter Propping Vinay Puri Digby J Quested Emma M Quinn Josep Antoni Ramos-Quiroga Henrik B Rasmussen Soumya Raychaudhuri Karola Rehnström Andreas Reif Marta Ribasés John P Rice Marcella Rietschel Kathryn Roeder Herbert Roeyers Lizzy Rossin Aribert Rothenberger Guy Rouleau Douglas Ruderfer Dan Rujescu Alan R Sanders Stephan J Sanders Susan L Santangelo Joseph A Sergeant Russell Schachar Martin Schalling Alan F Schatzberg William A Scheftner Gerard D Schellenberg Stephen W Scherer Nicholas J Schork Thomas G Schulze Johannes Schumacher Markus Schwarz Edward Scolnick Laura J Scott Jianxin Shi Paul D Shilling Stanley I Shyn Jeremy M Silverman Susan L Slager Susan L Smalley Johannes H Smit Erin N Smith Edmund J S Sonuga-Barke David St Clair Matthew State Michael Steffens Hans-Christoph Steinhausen John S Strauss Jana Strohmaier T Scott Stroup James S Sutcliffe Peter Szatmari Szabocls Szelinger Srinivasa Thirumalai Robert C Thompson Alexandre A Todorov Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Jim Van Os Astrid M Vicente Veronica J Vieland John B Vincent Peter M Visscher Christopher A Walsh Thomas H Wassink Stanley J Watson Myrna M Weissman Thomas Werge Thomas F Wienker Ellen M Wijsman Gonneke Willemsen Nigel Williams A Jeremy Willsey Stephanie H Witt Wei Xu Allan H Young Timothy W Yu Stanley Zammit Peter P Zandi Peng Zhang Frans G Zitman Sebastian Zöllner Bernie Devlin John R Kelsoe Pamela Sklar Mark J Daly Michael C O'Donovan Nicholas Craddock Patrick F Sullivan Jordan W Smoller Kenneth S Kendler Naomi R Wray

Nat Genet 2013 Sep 11;45(9):984-94. Epub 2013 Aug 11.

The University of Queensland, Queensland Brain Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/ng.2711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800159PMC
September 2013

Testing two models describing how methylome-wide studies in blood are informative for psychiatric conditions.

Epigenomics 2013 Aug;5(4):367-77

Center for Biomarker Research & Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, 1112 East Clay Street, PO Box 980533, Richmond, VA 23298, USA.

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http://dx.doi.org/10.2217/epi.13.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904748PMC
August 2013

High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot.

Epigenetics 2013 May 18;8(5):542-7. Epub 2013 Apr 18.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.4161/epi.24508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3741224PMC
May 2013

A mega-analysis of genome-wide association studies for major depressive disorder.

Authors:
Stephan Ripke Naomi R Wray Cathryn M Lewis Steven P Hamilton Myrna M Weissman Gerome Breen Enda M Byrne Douglas H R Blackwood Dorret I Boomsma Sven Cichon Andrew C Heath Florian Holsboer Susanne Lucae Pamela A F Madden Nicholas G Martin Peter McGuffin Pierandrea Muglia Markus M Noethen Brenda P Penninx Michele L Pergadia James B Potash Marcella Rietschel Danyu Lin Bertram Müller-Myhsok Jianxin Shi Stacy Steinberg Hans J Grabe Paul Lichtenstein Patrik Magnusson Roy H Perlis Martin Preisig Jordan W Smoller Kari Stefansson Rudolf Uher Zoltan Kutalik Katherine E Tansey Alexander Teumer Alexander Viktorin Michael R Barnes Thomas Bettecken Elisabeth B Binder René Breuer Victor M Castro Susanne E Churchill William H Coryell Nick Craddock Ian W Craig Darina Czamara Eco J De Geus Franziska Degenhardt Anne E Farmer Maurizio Fava Josef Frank Vivian S Gainer Patience J Gallagher Scott D Gordon Sergey Goryachev Magdalena Gross Michel Guipponi Anjali K Henders Stefan Herms Ian B Hickie Susanne Hoefels Witte Hoogendijk Jouke Jan Hottenga Dan V Iosifescu Marcus Ising Ian Jones Lisa Jones Tzeng Jung-Ying James A Knowles Isaac S Kohane Martin A Kohli Ania Korszun Mikael Landen William B Lawson Glyn Lewis Donald Macintyre Wolfgang Maier Manuel Mattheisen Patrick J McGrath Andrew McIntosh Alan McLean Christel M Middeldorp Lefkos Middleton Grant M Montgomery Shawn N Murphy Matthias Nauck Willem A Nolen Dale R Nyholt Michael O'Donovan Högni Oskarsson Nancy Pedersen William A Scheftner Andrea Schulz Thomas G Schulze Stanley I Shyn Engilbert Sigurdsson Susan L Slager Johannes H Smit Hreinn Stefansson Michael Steffens Thorgeir Thorgeirsson Federica Tozzi Jens Treutlein Manfred Uhr Edwin J C G van den Oord Gerard Van Grootheest Henry Völzke Jeffrey B Weilburg Gonneke Willemsen Frans G Zitman Benjamin Neale Mark Daly Douglas F Levinson Patrick F Sullivan

Mol Psychiatry 2013 Apr 3;18(4):497-511. Epub 2012 Apr 3.

Harvard University/Broad Institute, USA.

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http://dx.doi.org/10.1038/mp.2012.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837431PMC
April 2013

Genetic association between RGS1 and internalizing disorders.

Psychiatr Genet 2013 Apr;23(2):56-60

Departments of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Richmond, VA 23298-0126, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/YPG.0b013e32835d7048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3606916PMC
April 2013

Large-scale neurochemical metabolomics analysis identifies multiple compounds associated with methamphetamine exposure.

Metabolomics 2013 Apr 26;9(2):392-402. Epub 2012 Aug 26.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia Campus, Virginia Commonwealth University, McGuire Hall, 1112 East Clay Street, Richmond, VA 23298-0533, USA.

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http://dx.doi.org/10.1007/s11306-012-0456-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611962PMC
April 2013

MethylPCA: a toolkit to control for confounders in methylome-wide association studies.

BMC Bioinformatics 2013 Mar 2;14:74. Epub 2013 Mar 2.

Department of Biostatistics, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1186/1471-2105-14-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599654PMC
March 2013

Genome-wide association study of patient-rated and clinician-rated global impression of severity during antipsychotic treatment.

Pharmacogenet Genomics 2013 Feb;23(2):69-77

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298-0581, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835ca260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922978PMC
February 2013

Estimation of CpG coverage in whole methylome next-generation sequencing studies.

BMC Bioinformatics 2013 Feb 12;14:50. Epub 2013 Feb 12.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, 1112 East Clay Street, P.O. Box 980533, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1186/1471-2105-14-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599116PMC
February 2013

Methylome-wide comparison of human genomic DNA extracted from whole blood and from EBV-transformed lymphocyte cell lines.

Eur J Hum Genet 2012 Sep 29;20(9):953-5. Epub 2012 Feb 29.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1038/ejhg.2012.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3421118PMC
September 2012

The influence of five monoamine genes on trajectories of depressive symptoms across adolescence and young adulthood.

Dev Psychopathol 2012 Feb;24(1):267-85

Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, McGuire Hall, Room 216A, 1112 East Clay Street, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1017/S0954579411000824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515661PMC
February 2012

Analysis of efficacy and side effects in CATIE demonstrates drug response subgroups and potential for personalized medicine.

Schizophr Res 2011 Nov 27;132(2-3):114-20. Epub 2011 Aug 27.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298-0581, USA.

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http://dx.doi.org/10.1016/j.schres.2011.07.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195895PMC
November 2011

Epstein-barr virus transformed DNA as a source of false positive findings in methylation studies of psychiatric conditions.

Biol Psychiatry 2011 Sep 15;70(5):e25-6; author reply e27-8. Epub 2011 Apr 15.

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http://dx.doi.org/10.1016/j.biopsych.2011.01.042DOI Listing
September 2011

Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.

Neuropsychopharmacology 2011 Feb 24;36(3):616-26. Epub 2010 Nov 24.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA 23298-0533, USA.

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http://dx.doi.org/10.1038/npp.2010.193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055694PMC
February 2011

MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders.

Schizophr Res 2010 Dec 2;124(1-3):183-91. Epub 2010 Aug 2.

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Medical College of Virginia of Virginia Commonwealth University, Richmond, VA 23298-0424, USA.

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http://dx.doi.org/10.1016/j.schres.2010.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4373420PMC
December 2010

(1)H nuclear magnetic resonance metabolomics analysis identifies novel urinary biomarkers for lung function.

J Proteome Res 2010 Jun;9(6):3083-90

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia 23298, USA.

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http://dx.doi.org/10.1021/pr1000048DOI Listing
June 2010

Estimating effect sizes in genome-wide association studies.

Behav Genet 2010 May 6;40(3):394-403. Epub 2010 Jan 6.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, P.O. Box 980533, Richmond, VA 23298-0533, USA.

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http://dx.doi.org/10.1007/s10519-009-9321-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923086PMC
May 2010

Association study between GABA receptor genes and anxiety spectrum disorders.

Depress Anxiety 2009 ;26(11):998-1003

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298-0126, USA.

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http://dx.doi.org/10.1002/da.20628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783721PMC
February 2010

Estimating the number and size of the main effects in genome-wide case-control association studies.

BMC Proc 2007 18;1 Suppl 1:S143. Epub 2007 Dec 18.

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, 800 East Leigh Street, Biotech 1, VIPBG, Suite 1-130, Richmond, Virginia 23219, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367536PMC
http://dx.doi.org/10.1186/1753-6561-1-S1-S143DOI Listing
December 2009

In silico whole genome association scan for murine prepulse inhibition.

PLoS One 2009 16;4(4):e5246. Epub 2009 Apr 16.

Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, Richmond, VA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005246PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666808PMC
July 2009

In silico whole genome association scan for murine prepulse inhibition.

PLoS One 2009 16;4(4):e5246. Epub 2009 Apr 16.

Center for Biomarker Research and Personalized Medicine, Virginia Commonwealth University, Richmond, VA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005246PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666808PMC
July 2009

Estimating the posterior probability that genome-wide association findings are true or false.

Bioinformatics 2009 Jul 6;25(14):1807-13. Epub 2009 May 6.

Center for Biomarker Research and Personalized Medicine, School of Pharmacy, Medical College of Virginia, Virginia Commonwealth University, 1112 East Clay Street, PO Box 980533, Richmond, Virginia 23298, USA.

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http://dx.doi.org/10.1093/bioinformatics/btp305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2705227PMC
July 2009

Asthma pharmacogenetic study using finite mixture models to handle drug-response heterogeneity.

Pharmacogenomics 2009 May;10(5):753-67

Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298-0003, USA.

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http://dx.doi.org/10.2217/pgs.09.19DOI Listing
May 2009

A systematic method for estimating individual responses to treatment with antipsychotics in CATIE.

Schizophr Res 2009 Jan 18;107(1):13-21. Epub 2008 Oct 18.

Center for Biomarker Research and Personalized Medicine, Medical College of Virginia of Virginia Commonwealth University, Richmond VA, USA.

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http://dx.doi.org/10.1016/j.schres.2008.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652489PMC
January 2009

Model-based gene selection shows engrailed 1 is associated with antipsychotic response.

Pharmacogenet Genomics 2008 Sep;18(9):751-9

Center for Biomarker Research and Personalized Medicine, Department of Pharmacy, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, VA 23298, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32830162bcDOI Listing
September 2008

Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism.

Arch Gen Psychiatry 2008 Sep;65(9):1062-71

Center for Biomarker Research and Personalized Medicine, Medical College of Virginia, Virginia Commonwealth University, PO Box 980533, Richmond, VA 23298-0533, USA.

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http://archpsyc.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archpsyc.65.9.1062DOI Listing
September 2008

Catechol-O-methyltransferase contributes to genetic susceptibility shared among anxiety spectrum phenotypes.

Biol Psychiatry 2008 Aug 23;64(4):302-10. Epub 2008 Apr 23.

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, 23298-0126, USA.

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http://dx.doi.org/10.1016/j.biopsych.2008.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597663PMC
August 2008

Controlling false discoveries in genetic studies.

Am J Med Genet B Neuropsychiatr Genet 2008 Jul;147B(5):637-44

Center for Biomarker Research and Personalized Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298-0533, USA.

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July 2008

Lack of association between the amiloride-sensitive cation channel 2 (ACCN2) gene and anxiety spectrum disorders.

Psychiatr Genet 2008 Apr;18(2):73-9

Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298-0126, USA.

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April 2008

Twins and the study of rater (dis)agreement.

Psychol Methods 2007 Dec;12(4):451-466

Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University School of Medicine.

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http://doi.apa.org/getdoi.cfm?doi=10.1037/1082-989X.12.4.451
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December 2007

Optimization of two-stage genetic designs where data are combined using an accurate and efficient approximation for Pearson's statistic.

Biometrics 2006 Dec;62(4):1132-7

Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Medical College of Virginia of Virginia Commonwealth University, P.O. Box 980126, Richmond, Virginia 23298-0126, U.S.A.

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http://dx.doi.org/10.1111/j.1541-0420.2006.00583.xDOI Listing
December 2006

Ethnic differences in birth weight: maternal effects emerge from an analysis involving mixed-race us couples.

Ethn Dis 2006 ;16(3):706-11

Medical College of Virginia of Virginia Commonwealth University, Richmond, Virginia 23298-0126, USA.

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October 2006

Accurate and efficient power calculations for 2 x m tables in unmatched case-control designs.

Stat Med 2006 Aug;25(15):2632-46

Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, 23298-0126, USA.

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http://dx.doi.org/10.1002/sim.2269DOI Listing
August 2006

A method for analyzing strain differences in acquisition of IV cocaine self-administration in mice.

Behav Genet 2006 Jul 4;36(4):525-35. Epub 2006 Apr 4.

Virginia Institute of Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298-0126 USA.

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http://dx.doi.org/10.1007/s10519-006-9068-5DOI Listing
July 2006

A cautionary note on the use of simulation procedures for analyzing contingency tables containing small expected cell frequencies.

Am J Med Genet B Neuropsychiatr Genet 2006 Jun;141B(4):414-7

Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond, 23298-0126, USA.

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http://dx.doi.org/10.1002/ajmg.b.30268DOI Listing
June 2006

Variance component analysis of polymorphic metabolic systems.

J Theor Biol 2006 May 28;240(1):149-59. Epub 2005 Nov 28.

Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia, Virginia Commonwealth University, Biotech 1, 800 East Leigh Street, Richmond, VA 23298-0126, USA.

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http://dx.doi.org/10.1016/j.jtbi.2005.09.011DOI Listing
May 2006

Multivariate adaptive regression splines: a powerful method for detecting disease-risk relationship differences among subgroups.

Stat Med 2006 Apr;25(8):1355-67

Massey Cancer Center, Virginia Commonwealth University, Virginia Institute for Psychiatric and Behavioral Genetics, P.O. Box 980003, Richmond, VA 23298-0003, USA.

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April 2006

Factor structure and external validity of the PANSS revisited.

Schizophr Res 2006 Feb 17;82(2-3):213-23. Epub 2005 Oct 17.

Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia of Virginia Commonwealth University, P.O. Box 980126, Richmond VA 23298-0126, USA.

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February 2006

A framework for controlling false discovery rates and minimizing the amount of genotyping in the search for disease mutations.

Hum Hered 2003 ;56(4):188-99

Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia/Virginia Commonwealth University, PO Box 980126, Richmond, VA 23298-0126, USA.

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http://dx.doi.org/10.1159/000076393DOI Listing
November 2004

lga972: a cross-platform application for optimizing LD studies using a genetic algorithm.

Bioinformatics 2004 Nov 4;20(17):3244-5. Epub 2004 Jun 4.

Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia of Virginia Commonwealth University, Richmond, VA 23298-0126, USA.

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http://dx.doi.org/10.1093/bioinformatics/bth348DOI Listing
November 2004

Modeling with measured genotypes: effects of the vitamin D receptor gene, age, and latent genetic and environmental factors on bone mineral density.

Behav Genet 2004 Mar;34(2):197-206

Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia, PO Box 980126, Richmond, VA 23298-0126, USA.

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http://dx.doi.org/10.1023/B:BEGE.0000013733.38236.d1DOI Listing
March 2004

A study of parent ratings of internalizing and externalizing problem behavior in 12-year-old twins.

J Am Acad Child Adolesc Psychiatry 2003 Nov;42(11):1351-9

Department of Biological Psychiatry, Vrije Universiteit, Room 1F 66, van der Boechorststraat 1, 1081 BT Amsterdam, the Netherlands.

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http://dx.doi.org/10.1097/01.CHI.0000085755.71002.5dDOI Listing
November 2003

False discoveries and models for gene discovery.

Trends Genet 2003 Oct;19(10):537-42

Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298-0126, USA.

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http://dx.doi.org/10.1016/j.tig.2003.08.003DOI Listing
October 2003

Genetic and environmental contributions to stability and change in children's internalizing and externalizing problems.

J Am Acad Child Adolesc Psychiatry 2003 Oct;42(10):1212-20

Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands.

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October 2003

Normal variation and abnormality: an empirical study of the liability distributions underlying depression and delinquency.

J Child Psychol Psychiatry 2003 Feb;44(2):180-92

Department of Psychiatry, Medical College of Virginia of Virginia Commonwealth University, Richmond 23298-0126, USA.

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February 2003

Moderators of blood pressure development from childhood to adulthood: a 10-year longitudinal study.

J Pediatr 2002 Dec;141(6):770-9

Georgia Prevention Institute, Medical College of Georgia, Augusta 30912, USA.

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http://dx.doi.org/10.1067/mpd.2002.128113DOI Listing
December 2002

Growth of left ventricular mass in African American and European American youth.

Hypertension 2002 May;39(5):943-51

Georgia Prevention Institute, Medical College of Georgia, Augusta.

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http://dx.doi.org/10.1161/01.hyp.0000015612.73413.91DOI Listing
May 2002