Edwin Cuppen

Edwin Cuppen

UNVERIFIED PROFILE

Are you Edwin Cuppen?   Register this Author

Register author
Edwin Cuppen

Edwin Cuppen

Publications by authors named "Edwin Cuppen"

Are you Edwin Cuppen?   Register this Author

100Publications

3454Reads

24Profile Views

Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer.

Genome Res 2019 07 20;29(7):1067-1077. Epub 2019 Jun 20.

Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.246223.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6633256PMC
July 2019

Portrait of a cancer: mutational signature analyses for cancer diagnostics.

BMC Cancer 2019 May 15;19(1):457. Epub 2019 May 15.

Center for Molecular Medicine and Oncode Institute, University Medical Centre Utrecht, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12885-019-5677-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521503PMC
May 2019

Early divergence of mutational processes in human fetal tissues.

Sci Adv 2019 May 29;5(5):eaaw1271. Epub 2019 May 29.

Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584 CG Utrecht, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/sciadv.aaw1271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541467PMC
May 2019

A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells.

Mol Cell Proteomics 2018 10 3;17(10):1892-1908. Epub 2018 Jul 3.

From the ‡Biomolecular Mass Spectrometry and Proteomics Group, Utrecht Institute for Pharmaceutical Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands;

View Article

Download full-text PDF

Source
http://www.mcponline.org/lookup/doi/10.1074/mcp.RA117.000486
Publisher Site
http://dx.doi.org/10.1074/mcp.RA117.000486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166676PMC
October 2018

MutationalPatterns: comprehensive genome-wide analysis of mutational processes.

Genome Med 2018 04 25;10(1):33. Epub 2018 Apr 25.

Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Universiteitsweg 100, 3584, CG, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13073-018-0539-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922316PMC
April 2018

Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures.

Nat Protoc 2018 Jan 7;13(1):59-78. Epub 2017 Dec 7.

Center for Molecular Medicine and Oncode Institute, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2017.111DOI Listing
January 2018

Troy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidney.

Proc Natl Acad Sci U S A 2017 12 13;114(52):E11190-E11198. Epub 2017 Dec 13.

Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences, 3584 CT Utrecht, The Netherlands;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1714145115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748200PMC
December 2017

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.

Science 2017 10 14;358(6360):234-238. Epub 2017 Sep 14.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, 3584CT Utrecht, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aao3130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038908PMC
October 2017

The Genomic Scrapheap Challenge; Extracting Relevant Data from Unmapped Whole Genome Sequencing Reads, Including Strain Specific Genomic Segments, in Rats.

PLoS One 2016 8;11(8):e0160036. Epub 2016 Aug 8.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Centre Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160036PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976967PMC
August 2017

Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids.

Proc Natl Acad Sci U S A 2017 03 7;114(12):E2357-E2364. Epub 2017 Mar 7.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center (UMC) Utrecht, 3584 CT Utrecht, The Netherlands;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1701219114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373343PMC
March 2017

The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies.

Authors:
Claire Redin Harrison Brand Ryan L Collins Tammy Kammin Elyse Mitchell Jennelle C Hodge Carrie Hanscom Vamsee Pillalamarri Catarina M Seabra Mary-Alice Abbott Omar A Abdul-Rahman Erika Aberg Rhett Adley Sofia L Alcaraz-Estrada Fowzan S Alkuraya Yu An Mary-Anne Anderson Caroline Antolik Kwame Anyane-Yeboa Joan F Atkin Tina Bartell Jonathan A Bernstein Elizabeth Beyer Ian Blumenthal Ernie M H F Bongers Eva H Brilstra Chester W Brown Hennie T Brüggenwirth Bert Callewaert Colby Chiang Ken Corning Helen Cox Edwin Cuppen Benjamin B Currall Tom Cushing Dezso David Matthew A Deardorff Annelies Dheedene Marc D'Hooghe Bert B A de Vries Dawn L Earl Heather L Ferguson Heather Fisher David R FitzPatrick Pamela Gerrol Daniela Giachino Joseph T Glessner Troy Gliem Margo Grady Brett H Graham Cristin Griffis Karen W Gripp Andrea L Gropman Andrea Hanson-Kahn David J Harris Mark A Hayden Rosamund Hill Ron Hochstenbach Jodi D Hoffman Robert J Hopkin Monika W Hubshman A Micheil Innes Mira Irons Melita Irving Jessie C Jacobsen Sandra Janssens Tamison Jewett John P Johnson Marjolijn C Jongmans Stephen G Kahler David A Koolen Jerome Korzelius Peter M Kroisel Yves Lacassie William Lawless Emmanuelle Lemyre Kathleen Leppig Alex V Levin Haibo Li Hong Li Eric C Liao Cynthia Lim Edward J Lose Diane Lucente Michael J Macera Poornima Manavalan Giorgia Mandrile Carlo L Marcelis Lauren Margolin Tamara Mason Diane Masser-Frye Michael W McClellan Cinthya J Zepeda Mendoza Björn Menten Sjors Middelkamp Liya R Mikami Emily Moe Shehla Mohammed Tarja Mononen Megan E Mortenson Graciela Moya Aggie W Nieuwint Zehra Ordulu Sandhya Parkash Susan P Pauker Shahrin Pereira Danielle Perrin Katy Phelan Raul E Piña Aguilar Pino J Poddighe Giulia Pregno Salmo Raskin Linda Reis William Rhead Debra Rita Ivo Renkens Filip Roelens Jayla Ruliera Patrick Rump Samantha L P Schilit Ranad Shaheen Rebecca Sparkes Erica Spiegel Blair Stevens Matthew R Stone Julia Tagoe Joseph V Thakuria Bregje W van Bon Jiddeke van de Kamp Ineke van Der Burgt Ton van Essen Conny M van Ravenswaaij-Arts Markus J van Roosmalen Sarah Vergult Catharina M L Volker-Touw Dorothy P Warburton Matthew J Waterman Susan Wiley Anna Wilson Maria de la Concepcion A Yerena-de Vega Roberto T Zori Brynn Levy Han G Brunner Nicole de Leeuw Wigard P Kloosterman Erik C Thorland Cynthia C Morton James F Gusella Michael E Talkowski

Nat Genet 2017 01 14;49(1):36-45. Epub 2016 Nov 14.

Molecular Neurogenetics Unit, Center for Human Genetic Research, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307971PMC
January 2017

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer.

J Natl Cancer Inst 2016 11 5;108(11). Epub 2016 Jul 5.

Affiliations of authors: Division of Molecular Pathology and Cancer Genomics Centre Netherlands (PtB, PK, EvdB, UB, MdM, EL, LM, JdR, JW, JJ), Division of Molecular Carcinogenesis (IM), Department of Epidemiology and Biostatistics (KJ), and Family Cancer Clinic and Department of Pathology (FH), The Netherlands Cancer Institute, Amsterdam, the Netherlands; Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain (CM, ME); The Breakthrough Breast Cancer Research Centre, Institute of Cancer Research, London, UK (HG, NT); Laboratory of Preclinical Investigation, Translational Research Department, Curie Institute, Paris, France (EM); Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands (WK, MvR, KD, EC); Department of Physiological Sciences II, School of Medicine, University of Barcelona, Barcelona, Catalonia, Spain (ME); Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain (ME).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djw148DOI Listing
November 2016

Systematic analysis of chromatin interactions at disease associated loci links novel candidate genes to inflammatory bowel disease.

Genome Biol 2016 11 30;17(1):247. Epub 2016 Nov 30.

Department of Pediatric Gastroenterology, Wilhelmina Children's Hospital, University Medical Center Utrecht, Huispostnummer KA.03.019.0, Lundlaan 6, P.O. Box 85090, 3508, AB, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13059-016-1100-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131449PMC
November 2016

Lack of major genome instability in tumors of p53 null rats.

PLoS One 2015 26;10(3):e0122066. Epub 2015 Mar 26.

Hubrecht Institute, KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0122066PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4374866PMC
March 2016

Epigenomic annotation of gene regulatory alterations during evolution of the primate brain.

Nat Neurosci 2016 Mar 25;19(3):494-503. Epub 2016 Jan 25.

Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nn.4229DOI Listing
March 2016

Genetic etiology of renal agenesis: fine mapping of Renag1 and identification of Kit as the candidate functional gene.

PLoS One 2015 18;10(2):e0118147. Epub 2015 Feb 18.

McArdle Laboratory for Cancer Research, Department of Oncology, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America; Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, United States of America; University of Wisconsin Carbone Cancer Center, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.

View Article

Download full-text PDF

Source
http://edoc.mdc-berlin.de/14656/1/14656oa.pdf
Web Search
http://dx.plos.org/10.1371/journal.pone.0118147
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118147PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333340PMC
December 2015

A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes.

Diabetologia 2015 Dec 12;58(12):2800-9. Epub 2015 Sep 12.

Institute of Clinical Biochemistry, Hannover Medical School, 30623, Hannover, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00125-015-3757-7DOI Listing
December 2015

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases.

Proc Natl Acad Sci U S A 2015 Oct 12;112(43):13308-11. Epub 2015 Oct 12.

Department of Molecular Oncology, The Netherlands Cancer Institute, 1066 CX, Amsterdam, The Netherlands; Cancer Genomics.nl, 3584 CG Utrecht, The Netherlands; Foundation Hubrecht Organoid Technology (HUB), 3584 CT, Utrecht, The Netherlands; Department of Medical Oncology, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1516689112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629330PMC
October 2015

Toward effective software solutions for big biology.

Nat Biotechnol 2015 Jul;33(7):686-7

Office of the Director, The National Institutes of Health, Bethesda, Maryland, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.3240DOI Listing
July 2015

Sambamba: fast processing of NGS alignment formats.

Bioinformatics 2015 Jun 19;31(12):2032-4. Epub 2015 Feb 19.

Department of Statistical Simulation, St. Petersburg State University, St. Petersburg, Russia, Illumina Cambridge, Cambridge, UK, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands, Department of Medical Genetics, Institute for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands and Department of Nematology, Wageningen University, Wageningen, The Netherlands Department of Statistical Simulation, St. Petersburg State University, St. Petersburg, Russia, Illumina Cambridge, Cambridge, UK, Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands, Department of Medical Genetics, Institute for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands and Department of Nematology, Wageningen University, Wageningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btv098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765878PMC
June 2015

Effective Therapeutic Intervention and Comprehensive Genetic Analysis of mTOR Signaling in PEComa: A Case Report.

Anticancer Res 2015 Jun;35(6):3399-403

Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
June 2015

Pluripotency in the light of the developmental hourglass.

Biol Rev Camb Philos Soc 2015 May 23;90(2):428-43. Epub 2014 May 23.

Hubrecht Institute, KNAW and University Medical Center Utrecht, Utrecht 3584 CT, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/brv.12117DOI Listing
May 2015

Sequential cancer mutations in cultured human intestinal stem cells.

Nature 2015 May 29;521(7550):43-7. Epub 2015 Apr 29.

1] Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584CT Utrecht, The Netherlands [2] Cancer Genomics Netherlands, UMC Utrecht, 3584CG Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature14415DOI Listing
May 2015

Translational regulation shapes the molecular landscape of complex disease phenotypes.

Nat Commun 2015 May 26;6:7200. Epub 2015 May 26.

Cardiovascular and Metabolic Sciences, Max-Delbrück-Center for Molecular Medicine (MDC) in the Helmholtz Association, Robert-Rossle-Strasse 10, 13125 Berlin, Germany.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ncomms8200
Publisher Site
http://dx.doi.org/10.1038/ncomms8200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455061PMC
May 2015

Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance.

Haematologica 2015 Apr 5;100(4):e132-6. Epub 2014 Dec 5.

Department of Pediatric Oncology/Hematology, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam Individualized Therapies for Children with Cancer Study Group Dutch Childhood Oncology Group, The Hague, The Netherlands

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2014.112995DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4380734PMC
April 2015

Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts.

Cell Stem Cell 2015 Feb 22;16(2):158-70. Epub 2015 Jan 22.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Centre Utrecht, CancerGenomiCs.nl, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2014.12.006DOI Listing
February 2015

Simultaneous detection of clinically relevant mutations and amplifications for routine cancer pathology.

J Mol Diagn 2015 Jan 24;17(1):10-8. Epub 2014 Oct 24.

Department of Medical Oncology, University Medical Center Utrecht, Heidelberglaan Utrecht, Utrecht, the Netherlands; Netherlands Center for Personalized Cancer Treatment, Universiteitsweg Utrecht, Utrecht, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2014.09.004DOI Listing
January 2015

Rb and FZR1/Cdh1 determine CDK4/6-cyclin D requirement in C. elegans and human cancer cells.

Nat Commun 2015 Jan 6;6:5906. Epub 2015 Jan 6.

Developmental Biology, Faculty of Sciences, Department of Biology, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncomms6906DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4354291PMC
January 2015

Large-scale identification of coregulated enhancer networks in the adult human brain.

Cell Rep 2014 Oct 16;9(2):767-79. Epub 2014 Oct 16.

Hubrecht Institute-KNAW & University Medical Center Utrecht, Uppsalalaan 8, 3584CT, Utrecht, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.09.023DOI Listing
October 2014

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Cell 2014 Sep 4;159(1):163-175. Epub 2014 Sep 4.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT, Utrecht, Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2014.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772677PMC
September 2014

Natural variation of histone modification and its impact on gene expression in the rat genome.

Genome Res 2014 Jun 2;24(6):942-53. Epub 2014 May 2.

Max-Delbrück-Center for Molecular Medicine (MDC), 13125 Berlin, Germany; DZHK (German Centre for Cardiovascular Research), Partner site Berlin, 13125 Berlin, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.169029.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032858PMC
June 2014

Many inflammatory bowel disease risk loci include regions that regulate gene expression in immune cells and the intestinal epithelium.

Gastroenterology 2014 Apr 12;146(4):1040-7. Epub 2013 Dec 12.

Division of Pediatrics, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2013.12.003DOI Listing
April 2014

Wnt-induced transcriptional activation is exclusively mediated by TCF/LEF.

EMBO J 2014 Jan 10;33(2):146-56. Epub 2014 Jan 10.

Hubrecht Institute-KNAW, University Medical Centre Utrecht, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://emboj.embopress.org/cgi/doi/10.1002/embj.201385358
Publisher Site
http://dx.doi.org/10.1002/embj.201385358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989608PMC
January 2014

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients.

Cell Stem Cell 2013 Dec;13(6):653-8

Hubrecht Institute/KNAW, Uppsalalaan 8, Utrecht 3584 CT, The Netherlands; University Medical Center Utrecht, Uppsalalaan 8, Utrecht 3584 CT, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.stem.2013.11.002DOI Listing
December 2013

A deep sequencing approach to uncover the miRNOME in the human heart.

PLoS One 2013 27;8(2):e57800. Epub 2013 Feb 27.

Department of Cardiology, CARIM School for Cardiovascular Diseases, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057800PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583901PMC
September 2013

Challenges for implementing next-generation sequencing-based genome diagnostics: it's also the people, not just the machines.

Per Med 2013 Jul;10(5):473-484

Department of Medical Genetics, Utrecht University Medical Centre, Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pme.13.41DOI Listing
July 2013

Chromothripsis in congenital disorders and cancer: similarities and differences.

Curr Opin Cell Biol 2013 Jun 13;25(3):341-8. Epub 2013 Mar 13.

Department of Medical Genetics, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09550674130003
Publisher Site
http://dx.doi.org/10.1016/j.ceb.2013.02.008DOI Listing
June 2013

Nucleosomal DNA binding drives the recognition of H3K36-methylated nucleosomes by the PSIP1-PWWP domain.

Epigenetics Chromatin 2013 May 8;6(1):12. Epub 2013 May 8.

NMR Spectroscopy Research Group, Bijvoet Center for Biomolecular Research, Utrecht University Utrecht, Padualaan 8, Utrecht, CH, 3854, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1756-8935-6-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663649PMC
May 2013

Application of exome sequencing in the search for genetic causes of rare disorders of copper metabolism.

Metallomics 2012 Jul 4;4(7):606-13. Epub 2012 May 4.

Department of Metabolic Diseases, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c2mt20034aDOI Listing
July 2012