Edward T Chouchani

Edward T Chouchani

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Edward T Chouchani

Edward T Chouchani

Publications by authors named "Edward T Chouchani"

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39Publications

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New Advances in Adaptive Thermogenesis: UCP1 and Beyond.

Cell Metab 2019 01 29;29(1):27-37. Epub 2018 Nov 29.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.11.002DOI Listing
January 2019

Coupling Krebs cycle metabolites to signalling in immunity and cancer.

Nat Metab 2019 Jan;1:16-33

Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/s42255-018-0014-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485344PMC
January 2019

Mechanisms of Mitochondria Assembly, Dynamics and Turnover in Health and Disease.

J Mol Biol 2018 12 11;430(24):4821-4822. Epub 2018 Nov 11.

Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD) and Institute for Mitochondrial Diseases and Aging, Medical Faculty, University of Cologne, Cologne, Germany, Center for Molecular Medicine (CMMC), University of Cologne, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2018.11.009DOI Listing
December 2018

Mitochondrial reactive oxygen species and adipose tissue thermogenesis: Bridging physiology and mechanisms.

J Biol Chem 2017 10 24;292(41):16810-16816. Epub 2017 Aug 24.

From the Dana-Farber Cancer Institute, Harvard Medical School and

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http://dx.doi.org/10.1074/jbc.R117.789628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641863PMC
October 2017

Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity.

Cell Metab 2017 Oct 24;26(4):660-671.e3. Epub 2017 Aug 24.

Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629120PMC
October 2017

Identification and quantification of protein -nitrosation by nitrite in the mouse heart during ischemia.

J Biol Chem 2017 09 14;292(35):14486-14495. Epub 2017 Jul 14.

the Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0XY, United Kingdom, and

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http://dx.doi.org/10.1074/jbc.M117.798744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582841PMC
September 2017

Stress turns on the heat: Regulation of mitochondrial biogenesis and UCP1 by ROS in adipocytes.

Adipocyte 2017 01 16;6(1):56-61. Epub 2016 Dec 16.

a Department of Nutrition and Integrative Physiology and Division of Endocrinology , Metabolism and Diabetes and Program in Molecular Medicine, University of Utah School of Medicine , Salt Lake City , Utah , USA.

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http://dx.doi.org/10.1080/21623945.2016.1273298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358708PMC
January 2017

Succinate metabolism: a new therapeutic target for myocardial reperfusion injury.

Cardiovasc Res 2016 07 18;111(2):134-41. Epub 2016 May 18.

Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK

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http://dx.doi.org/10.1093/cvr/cvw100DOI Listing
July 2016

Moving Forwards by Blocking Back-Flow: The Yin and Yang of MI Therapy.

Circ Res 2016 Mar;118(5):898-906

From the Department of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom (V.R.P., T.K.); Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA (E.T.C.); Department of Cell Biology, Harvard Medical School, Boston, MA (E.T.C.); MRC Mitochondrial Biology Unit, Cambridge, United Kingdom (M.P.M.); and Department of Anesthesiology, University of Rochester Medical Center, Rochester, NY (P.S.B.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.306569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809200PMC
March 2016

A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury.

Cell Metab 2016 Feb 14;23(2):254-63. Epub 2016 Jan 14.

MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.12.009DOI Listing
February 2016

A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat.

Cell 2015 Oct 22;163(3):643-55. Epub 2015 Oct 22.

Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Cell Biology, Harvard University Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.09.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656041PMC
October 2015

Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species.

J Biol Chem 2012 Oct 21;287(42):35153-60. Epub 2012 Aug 21.

Mitochondrial Biology Unit, Medical Research Council, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M112.400002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471752PMC
October 2012

Mitochondrial redox signalling at a glance.

J Cell Sci 2012 Feb;125(Pt 4):801-6

MRC Mitochondrial Biology Unit, Wellcome Trust-MRC Building, Hills Road, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1242/jcs.098475DOI Listing
February 2012

Proteomic approaches to the characterization of protein thiol modification.

Curr Opin Chem Biol 2011 Feb 2;15(1):120-8. Epub 2010 Dec 2.

MRC Mitochondrial Biology Unit, Hills Road, Cambridge CB2 0XY, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S13675931100016
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http://dx.doi.org/10.1016/j.cbpa.2010.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3087609PMC
February 2011

Quantification and identification of mitochondrial proteins containing vicinal dithiols.

Arch Biochem Biophys 2010 Dec 15;504(2):228-35. Epub 2010 Sep 15.

MRC Mitochondrial Biology Unit, Cambridge, UK.

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http://dx.doi.org/10.1016/j.abb.2010.09.003DOI Listing
December 2010

Measuring mitochondrial protein thiol redox state.

Methods Enzymol 2010 20;474:123-47. Epub 2010 Jun 20.

Medical Research Council Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Cambridge, UK.

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http://dx.doi.org/10.1016/S0076-6879(10)74008-8DOI Listing
October 2010