Edward R Whittemore

Edward R Whittemore

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Edward R Whittemore

Edward R Whittemore

Publications by authors named "Edward R Whittemore"

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Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of α7 nicotinic acetylcholine receptors.

J Med Chem 2013 Nov 30;56(21):8352-65. Epub 2013 Oct 30.

Department of Pharmacology, College of Medicine, University of California, Irvine , Med Surge 2, Room 372, Irvine, California 92697, United States.

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http://dx.doi.org/10.1021/jm400704gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912855PMC
November 2013

Limiting activity at beta1-subunit-containing GABAA receptor subtypes reduces ataxia.

J Pharmacol Exp Ther 2010 Mar 25;332(3):1040-53. Epub 2009 Nov 25.

Department of Pharmacology, School of Medicine, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1124/jpet.109.161885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2835428PMC
March 2010

Negative allosteric modulation of nicotinic acetylcholine receptors blocks nicotine self-administration in rats.

J Pharmacol Exp Ther 2007 Dec 14;323(3):907-15. Epub 2007 Sep 14.

Department of Pharmacology, School of Medicine, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1124/jpet.107.128751DOI Listing
December 2007

Enaminone amides as novel orally active GABAA receptor modulators.

J Med Chem 2007 Jul 16;50(14):3369-79. Epub 2007 Jun 16.

Department of Pharmacology, School of Medicine, Med Surge 2, University of California-Irvine, Irvine, California 92697, USA.

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http://dx.doi.org/10.1021/jm070083vDOI Listing
July 2007

Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators.

Proc Natl Acad Sci U S A 2007 May 30;104(19):8059-64. Epub 2007 Apr 30.

Department of Pharmacology, School of Medicine, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1073/pnas.0701321104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876571PMC
May 2007