Edward M Scolnick

Edward M Scolnick

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Edward M Scolnick

Edward M Scolnick

Publications by authors named "Edward M Scolnick"

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A vaccine to prevent cervical cancer: academic and industrial collaboration and a Lasker award.

Clin Transl Immunology 2018 28;7(1):e1002. Epub 2017 Dec 28.

Broad Institute of Harvard and Massachusetts Institute of Technology Cambridge MA USA.

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http://dx.doi.org/10.1002/cti2.1002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822403PMC
December 2017

The Path to New Therapies for Schizophrenia and Bipolar Illness.

FASEB J 2017 04;31(4):1254-1259

Stanley Center for Psychiatric Research, Broad Institute, Cambridge, Massachusetts, USA

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http://www.fasebj.org/doi/10.1096/fj.201700028
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http://dx.doi.org/10.1096/fj.201700028DOI Listing
April 2017

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.

Authors:
Christian R Marshall Daniel P Howrigan Daniele Merico Bhooma Thiruvahindrapuram Wenting Wu Douglas S Greer Danny Antaki Aniket Shetty Peter A Holmans Dalila Pinto Madhusudan Gujral William M Brandler Dheeraj Malhotra Zhouzhi Wang Karin V Fuentes Fajarado Michelle S Maile Stephan Ripke Ingrid Agartz Margot Albus Madeline Alexander Farooq Amin Joshua Atkins Silviu A Bacanu Richard A Belliveau Sarah E Bergen Marcelo Bertalan Elizabeth Bevilacqua Tim B Bigdeli Donald W Black Richard Bruggeman Nancy G Buccola Randy L Buckner Brendan Bulik-Sullivan William Byerley Wiepke Cahn Guiqing Cai Murray J Cairns Dominique Campion Rita M Cantor Vaughan J Carr Noa Carrera Stanley V Catts Kimberley D Chambert Wei Cheng C Robert Cloninger David Cohen Paul Cormican Nick Craddock Benedicto Crespo-Facorro James J Crowley David Curtis Michael Davidson Kenneth L Davis Franziska Degenhardt Jurgen Del Favero Lynn E DeLisi Dimitris Dikeos Timothy Dinan Srdjan Djurovic Gary Donohoe Elodie Drapeau Jubao Duan Frank Dudbridge Peter Eichhammer Johan Eriksson Valentina Escott-Price Laurent Essioux Ayman H Fanous Kai-How Farh Martilias S Farrell Josef Frank Lude Franke Robert Freedman Nelson B Freimer Joseph I Friedman Andreas J Forstner Menachem Fromer Giulio Genovese Lyudmila Georgieva Elliot S Gershon Ina Giegling Paola Giusti-Rodríguez Stephanie Godard Jacqueline I Goldstein Jacob Gratten Lieuwe de Haan Marian L Hamshere Mark Hansen Thomas Hansen Vahram Haroutunian Annette M Hartmann Frans A Henskens Stefan Herms Joel N Hirschhorn Per Hoffmann Andrea Hofman Hailiang Huang Masashi Ikeda Inge Joa Anna K Kähler René S Kahn Luba Kalaydjieva Juha Karjalainen David Kavanagh Matthew C Keller Brian J Kelly James L Kennedy Yunjung Kim James A Knowles Bettina Konte Claudine Laurent Phil Lee S Hong Lee Sophie E Legge Bernard Lerer Deborah L Levy Kung-Yee Liang Jeffrey Lieberman Jouko Lönnqvist Carmel M Loughland Patrik K E Magnusson Brion S Maher Wolfgang Maier Jacques Mallet Manuel Mattheisen Morten Mattingsdal Robert W McCarley Colm McDonald Andrew M McIntosh Sandra Meier Carin J Meijer Ingrid Melle Raquelle I Mesholam-Gately Andres Metspalu Patricia T Michie Lili Milani Vihra Milanova Younes Mokrab Derek W Morris Bertram Müller-Myhsok Kieran C Murphy Robin M Murray Inez Myin-Germeys Igor Nenadic Deborah A Nertney Gerald Nestadt Kristin K Nicodemus Laura Nisenbaum Annelie Nordin Eadbhard O'Callaghan Colm O'Dushlaine Sang-Yun Oh Ann Olincy Line Olsen F Anthony O'Neill Jim Van Os Christos Pantelis George N Papadimitriou Elena Parkhomenko Michele T Pato Tiina Paunio Diana O Perkins Tune H Pers Olli Pietiläinen Jonathan Pimm Andrew J Pocklington John Powell Alkes Price Ann E Pulver Shaun M Purcell Digby Quested Henrik B Rasmussen Abraham Reichenberg Mark A Reimers Alexander L Richards Joshua L Roffman Panos Roussos Douglas M Ruderfer Veikko Salomaa Alan R Sanders Adam Savitz Ulrich Schall Thomas G Schulze Sibylle G Schwab Edward M Scolnick Rodney J Scott Larry J Seidman Jianxin Shi Jeremy M Silverman Jordan W Smoller Erik Söderman Chris C A Spencer Eli A Stahl Eric Strengman Jana Strohmaier T Scott Stroup Jaana Suvisaari Dragan M Svrakic Jin P Szatkiewicz Srinivas Thirumalai Paul A Tooney Juha Veijola Peter M Visscher John Waddington Dermot Walsh Bradley T Webb Mark Weiser Dieter B Wildenauer Nigel M Williams Stephanie Williams Stephanie H Witt Aaron R Wolen Brandon K Wormley Naomi R Wray Jing Qin Wu Clement C Zai Rolf Adolfsson Ole A Andreassen Douglas H R Blackwood Elvira Bramon Joseph D Buxbaum Sven Cichon David A Collier Aiden Corvin Mark J Daly Ariel Darvasi Enrico Domenici Tõnu Esko Pablo V Gejman Michael Gill Hugh Gurling Christina M Hultman Nakao Iwata Assen V Jablensky Erik G Jönsson Kenneth S Kendler George Kirov Jo Knight Douglas F Levinson Qingqin S Li Steven A McCarroll Andrew McQuillin Jennifer L Moran Bryan J Mowry Markus M Nöthen Roel A Ophoff Michael J Owen Aarno Palotie Carlos N Pato Tracey L Petryshen Danielle Posthuma Marcella Rietschel Brien P Riley Dan Rujescu Pamela Sklar David St Clair James T R Walters Thomas Werge Patrick F Sullivan Michael C O'Donovan Stephen W Scherer Benjamin M Neale Jonathan Sebat

Nat Genet 2017 01 21;49(1):27-35. Epub 2016 Nov 21.

Beyster Center for Psychiatric Genomics, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1038/ng.3725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737772PMC
January 2017

A polygenic burden of rare disruptive mutations in schizophrenia.

Nature 2014 Feb 22;506(7487):185-90. Epub 2014 Jan 22.

1] Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [3] Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.

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http://dx.doi.org/10.1038/nature12975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136494PMC
February 2014

Validating therapeutic targets through human genetics.

Nat Rev Drug Discov 2013 Aug 19;12(8):581-94. Epub 2013 Jul 19.

Division of Rheumatology, Immunology and Allergy, Brigham And Women's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nrd4051DOI Listing
August 2013

Chemical genetics identifies small-molecule modulators of neuritogenesis involving neuregulin-1/ErbB4 signaling.

ACS Chem Neurosci 2010 Jan;1(4):325-342

Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, 7 Cambridge Center, Cambridge, MA, 02142, USA.

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http://dx.doi.org/10.1021/cn900046aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2873204PMC
January 2010

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

Nat Genet 2008 Sep;40(9):1056-8

Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

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http://research.mssm.edu/statgen/library/ferreira-2008-bipol
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http://www.nature.com/doifinder/10.1038/ng.209
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http://dx.doi.org/10.1038/ng.209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703780PMC
September 2008

Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia.

Am J Hum Genet 2006 Nov 3;79(5):903-9. Epub 2006 Oct 3.

Psychiatric Disease Initiative, Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA, USA.

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http://dx.doi.org/10.1086/508942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698571PMC
November 2006

Schizophrenia: do the genetics and neurobiology of neuregulin provide a pathogenesis model?

Harv Rev Psychiatry 2006 Mar-Apr;14(2):64-77

Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 02139, USA.

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http://dx.doi.org/10.1080/10673220600642960DOI Listing
September 2006

Mechanisms of action of medicines for schizophrenia and bipolar illness: status and limitations.

Biol Psychiatry 2006 Jun 17;59(11):1039-45. Epub 2006 Apr 17.

Psychiatric Disease Initiative, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02139, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000632230600240
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http://dx.doi.org/10.1016/j.biopsych.2006.02.022DOI Listing
June 2006

Discovery and development of antidepressants: a perspective from a pharmaceutical discovery company.

Biol Psychiatry 2002 Aug;52(3):154-6

Merck & Co., Inc., WP26-215, West Point, PA 19486, USA.

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http://dx.doi.org/10.1016/s0006-3223(01)01353-1DOI Listing
August 2002

A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease.

Proc Natl Acad Sci U S A 2002 May 7;99(10):6603-6. Epub 2002 May 7.

Department of High Throughput Screening and Automation, Merck Research Laboratories, Rahway, NJ 07065-0900, USA.

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http://dx.doi.org/10.1073/pnas.062171599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC124449PMC
May 2002