Edward Leung

Edward Leung

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Edward Leung

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Smartphone EEG and remote online interpretation for children with epilepsy in the Republic of Guinea: Quality, characteristics, and practice implications.

Seizure 2019 Oct 31;71:93-99. Epub 2019 May 31.

Department of Neurology, Massachusetts General Hospital, Boston, MA, USA; Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2019.05.025DOI Listing
October 2019

Development and validation of a targeted affinity-enrichment and LC-MS/MS proteomics approach for the therapeutic monitoring of adalimumab.

Clin Chim Acta 2018 Aug 9;483:308-314. Epub 2018 May 9.

Department of Pathology, Pritzker School of Medicine, The University of Chicago, Chicago, IL, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S00098981183022
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http://dx.doi.org/10.1016/j.cca.2018.05.015DOI Listing
August 2018

Staff preparedness for providing palliative and end-of-life care in long-term care homes: Instrument development and validation.

Geriatr Gerontol Int 2018 May 16;18(5):745-749. Epub 2018 Jan 16.

Hong Kong Association of Gerontology, Hong Kong, China.

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http://dx.doi.org/10.1111/ggi.13244DOI Listing
May 2018

Smith-Lemli-Opitz Syndrome in a newborn infant with developmental abnormalities and low endogenous cholesterol.

Clin Chim Acta 2018 Apr 31;479:208-211. Epub 2018 Jan 31.

Department of Pathology, Pritzker School of Medicine, The University of Chicago, United States.

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http://dx.doi.org/10.1016/j.cca.2018.01.027DOI Listing
April 2018

Efficacy of the Herpes Zoster Subunit Vaccine in Adults 70 Years of Age or Older.

N Engl J Med 2016 Sep;375(11):1019-32

From Westmead Institute for Medical Research, Westmead, NSW (A.L.C.), University of Sydney, Sydney (A.L.C.), the Department of Infectious Disease, Barwon Health, Deakin University, Geelong, VIC (E.A.), AusTrials and the Discipline of General Practice, School of Medicine, University of Queensland, Brisbane (F.L.), and Illawarra Health and Medical Research Institute, Graduate School of Medicine, University of Wollongong, Wollongong, NSW (W.Y.) - all in Australia; GSK Vaccines, King of Prussia, PA (H.L., T.C.H.); GSK Vaccines, Wavre, Belgium (M.K., O.G., C.V.A., T.Z., L.C., L.O.); Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic (R.C., J.S.); the Department of Family Medicine, Taipei Veterans General Hospital, and National Yang Ming University School of Medicine, Taipei, Taiwan (S.-J.H.); the Vaccine Research Unit, Fundación para el Fomento de la Investigación Sanitaria y Biomédica, Valencia, Spain (J.D.-D., J.P.-B.); the Departments of Pediatrics and Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.J.L.); Health Sciences North Research Institute, Sudbury, ON (J.E.M.), the Section of Infectious Diseases, University of British Colombia, Victoria (W.G.), PrimeHealth Clinical Research, Toronto (I.G.), and the Canadian Center for Vaccinology, IWK Health Center and Nova Scotia Health Authority, Dalhousie University, Halifax (S.A.M.) - all in Canada; Vaccine Research Center, University of Tampere, Tampere, Finland (T.V., A.A., T.K.); the Department of Dermatology, Aichi Medical University, Nagakute, Japan (D.W.); Instituto Dermatologico de Jalisco Dr. José Barba Rubio, Zapopan, Mexico (J.F.B.-G.); Jacksonville Center for Clinical Research, Jacksonville, FL (H.J.D.); the Division of Geriatric Medicine, Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong (E.L.); Center for Clinical Research, Sörmland County Council, Eskilstuna, and Uppsala University, Uppsala - both in Sweden (L.R.); and

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http://dx.doi.org/10.1056/NEJMoa1603800DOI Listing
September 2016

Diiodothyropropionic acid (DITPA) cross-reacts with thyroid function assays on different immunoassay platforms.

Clin Chim Acta 2016 Jan 10;453:203-4. Epub 2015 Dec 10.

Department of Pathology, The University of Chicago, United States.

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http://dx.doi.org/10.1016/j.cca.2015.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819893PMC
January 2016

A survey of morbidity and mortality review meetings in the general surgical units of the West of Scotland.

Scott Med J 2015 Nov 23;60(4):244-8. Epub 2015 Jul 23.

Consultant General and Colorectal Surgeon, Department of Surgery, Crosshouse Hospital, UK.

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http://dx.doi.org/10.1177/0036933015597179DOI Listing
November 2015

Management of lipoprotein X and its complications in a patient with primary sclerosing cholangitis.

Clin Lipidol 2015 Aug;10(4):305-312

Department of Medicine, University of Chicago, Chicago, IL, 60637,USA ; Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA ; Section of Endocrinology, Diabetes & Metabolism, University of Chicago, Chicago, IL, 60637,USA.

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https://www.futuremedicine.com/doi/10.2217/clp.15.23
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http://dx.doi.org/10.2217/clp.15.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578808PMC
August 2015

Transition State Features in the Hepatitis Delta Virus Ribozyme Reaction Revealed by Atomic Perturbations.

J Am Chem Soc 2015 Jul 14;137(28):8973-82. Epub 2015 Jul 14.

§Department of Biochemistry and Center for Proteomics, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, United States.

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http://dx.doi.org/10.1021/jacs.5b01189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758122PMC
July 2015

Physical and social activities mediate the associations between social network types and ventilatory function in Chinese older adults.

Health Psychol 2014 Jun;33(6):524-34

Department of Psychological and Brain Sciences, Indiana University.

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http://dx.doi.org/10.1037/hea0000026DOI Listing
June 2014

Clinical evaluation of the QMS® Tacrolimus immunoassay.

Clin Chim Acta 2014 Apr 8;431:270-5. Epub 2014 Feb 8.

Department of Pathology, Pritzker School of Medicine, The University of Chicago, Chicago, IL, United States.

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http://dx.doi.org/10.1016/j.cca.2014.01.027DOI Listing
April 2014

Childlessness and subjective well-being in Chinese widowed persons.

J Gerontol B Psychol Sci Soc Sci 2014 Jan 26;69(1):48-52. Epub 2013 Jun 26.

Correspondence should be addressed to Sheung-Tak Cheng, Department of Psychological Studies, Hong Kong Institute of Education, 10 Lo Ping Road, Tai Po, N.T., Hong Kong. E-mail:

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http://dx.doi.org/10.1093/geronb/gbt049DOI Listing
January 2014

Reducing the risk of hyperammonemia from transfusion of stored red blood cells.

Transfus Apher Sci 2013 Dec 29;49(3):459-62. Epub 2013 May 29.

Department of Pathology, The University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.transci.2013.05.002DOI Listing
December 2013

The effects of a foot and toenail care protocol for older adults.

Geriatr Nurs 2012 Nov-Dec;33(6):446-53. Epub 2012 Jun 9.

The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1016/j.gerinurse.2012.04.003DOI Listing
November 2013

Outcome of perinatal hypophosphatasia in manitoba mennonites: a retrospective cohort analysis.

JIMD Rep 2013 12;11:73-8. Epub 2013 Apr 12.

Manitoba Institute of Child Health and Department of Pediatrics and Child Health, University of Manitoba, AE308 - 820 Sherbrook St, R3A 1R9, Winnipeg, Manitoba, Canada,

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http://dx.doi.org/10.1007/8904_2013_224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755555PMC
August 2013

Social exchanges and subjective well-being: do sources of positive and negative exchanges matter?

J Gerontol B Psychol Sci Soc Sci 2011 Nov 9;66(6):708-18. Epub 2011 Jul 9.

Department of Psychological Studies, Hong Kong Institute of Education, 10 Lo Ping Road, Tai Po, New Territories, Hong Kong, China.

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http://dx.doi.org/10.1093/geronb/gbr061DOI Listing
November 2011

The mechanism of peptidyl transfer catalysis by the ribosome.

Annu Rev Biochem 2011 ;80:527-55

Department of Biochemistry and Molecular Biology, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1146/annurev-biochem-082108-165150DOI Listing
October 2011

Homemade laparoscopic simulators for surgical trainees.

Clin Teach 2011 Jun;8(2):118-21

Department of Surgery, Crosshouse Hospital, Kilmarnock, UK.

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http://dx.doi.org/10.1111/j.1743-498X.2011.00441.xDOI Listing
June 2011

Psychometric properties of the Chinese version of the European Heart Failure Self-care Behaviour Scale.

Int J Nurs Stud 2011 Apr;48(4):458-67

The Nethersole School of Nursing, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong.

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http://dx.doi.org/10.1016/j.ijnurstu.2010.08.011DOI Listing
April 2011

The use of charge flow and quenching (CFQ) to probe nucleic acid folds and folding.

Methods 2010 Oct 8;52(2):141-9. Epub 2010 Jun 8.

Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.ymeth.2010.06.006DOI Listing
October 2010

Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors.

Biochem Pharmacol 2010 May 21;79(10):1483-95. Epub 2010 Jan 21.

Department of Clinical and Experimental Medicine, Interdisciplinary Center for the Study of Inflammation, University of Ferrara, Italy.

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http://dx.doi.org/10.1016/j.bcp.2010.01.009DOI Listing
May 2010

Oxidative/nitrosative stress selectively altered A(2B) adenosine receptors in chronic obstructive pulmonary disease.

FASEB J 2010 Apr 14;24(4):1192-204. Epub 2009 Dec 14.

Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, via Fossato di Mortara 17-19, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1096/fj.09-139485DOI Listing
April 2010

A2A adenosine receptor overexpression and functionality, as well as TNF-alpha levels, correlate with motor symptoms in Parkinson's disease.

FASEB J 2010 Feb 23;24(2):587-98. Epub 2009 Sep 23.

Department of Clinical and Experimental Medicine, Pharmacology Section, University of Ferrara, via Fossato di Mortara 17-19 44100 Ferrara, Italy.

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http://dx.doi.org/10.1096/fj.09-141044DOI Listing
February 2010

Adenosine modulates HIF-1{alpha}, VEGF, IL-8, and foam cell formation in a human model of hypoxic foam cells.

Arterioscler Thromb Vasc Biol 2010 Jan 15;30(1):90-7. Epub 2009 Oct 15.

Chair of Pharmacology, Faculty of Medicine, University of Ferrara, Department of Clinical and Experimental Medicine, Pharmacology Unit, Via Fossato di Mortara 17-19, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1161/ATVBAHA.109.194902DOI Listing
January 2010

Social network types and subjective well-being in Chinese older adults.

J Gerontol B Psychol Sci Soc Sci 2009 Nov 9;64(6):713-22. Epub 2009 Oct 9.

Department of Applied Social Studies, City University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1093/geronb/gbp075DOI Listing
November 2009

LRRK2 Gly2385Arg mutation and clinical features in a Chinese population with early-onset Parkinson's disease compared to late-onset patients.

J Neural Transm (Vienna) 2008 Sep 4;115(9):1275-7. Epub 2008 Jun 4.

Department of Aged Care and Rehabilitation, Bankstown-Lidcombe Hospital, Locked bag 1600, Bankstown, NSW 2200, Australia.

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http://dx.doi.org/10.1007/s00702-008-0065-0DOI Listing
September 2008

Impact of oral health status on oral health-related quality of life in Chinese hospitalised geriatric patients.

Qual Life Res 2008 Apr 9;17(3):397-405. Epub 2008 Feb 9.

The Nethersole School of Nursing, The Chinese University of Hong Kong, Rm 729, Esther Lee Building, Shatin, New Territories, Hong Kong.

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http://dx.doi.org/10.1007/s11136-008-9314-9DOI Listing
April 2008

Laparoscopic colorectal resection does not reduce incisional hernia rates when compared with open colorectal resection.

Surg Endosc 2008 Mar;22(3):689-92

University Department of Surgery, Western Infirmary, Glasgow, G11 6NT, Scotland.

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http://dx.doi.org/10.1007/s00464-007-9462-yDOI Listing
March 2008

Thermodynamics of A2B adenosine receptor binding discriminates agonistic from antagonistic behaviour.

Biochem Pharmacol 2008 Jan 8;75(2):562-9. Epub 2007 Sep 8.

Department of Clinical and Experimental Medicine, Pharmacology Unit and Interdisciplinary Center for Study of Inflammation, Ferrara, Italy.

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http://dx.doi.org/10.1016/j.bcp.2007.09.003DOI Listing
January 2008

The A3 adenosine receptor: an enigmatic player in cell biology.

Pharmacol Ther 2008 Jan 22;117(1):123-40. Epub 2007 Sep 22.

Department of Clinical and Experimental Medicine, Pharmacology Unit and Interdisciplinary Center for the Study of Inflammation, Ferrara, Italy.

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http://dx.doi.org/10.1016/j.pharmthera.2007.09.002DOI Listing
January 2008

Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells.

Mol Pharmacol 2007 Jul 30;72(1):162-72. Epub 2007 Mar 30.

Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1124/mol.106.031849DOI Listing
July 2007

Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: focus on the A(3) adenosine subtype.

J Cell Physiol 2007 Jun;211(3):826-36

Department of Clinical and Experimental Medicine, Pharmacology Unit and Interdisciplinary Center for the Study of Inflammation, Ferrara, Italy.

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http://dx.doi.org/10.1002/jcp.20994DOI Listing
June 2007

Adenosine and lymphocyte regulation.

Purinergic Signal 2007 Mar 16;3(1-2):109-16. Epub 2007 Jan 16.

Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, Via Fossato di Mortara 17-19, 44100, Ferrara, Italy.

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http://dx.doi.org/10.1007/s11302-006-9042-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096755PMC
March 2007

Electron hole flow patterns through the RNA-cleaving 8-17 deoxyribozyme yield unusual information about its structure and folding.

Chem Biol 2007 Jan;14(1):41-51

Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, British Columbia, V5A 1S6, Canada.

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http://dx.doi.org/10.1016/j.chembiol.2006.11.006DOI Listing
January 2007

Novel selective antagonist radioligands for the pharmacological study of A(2B) adenosine receptors.

Purinergic Signal 2006 Nov 8;2(4):583-8. Epub 2006 Jul 8.

Department of Clinical and Experimental Medicine, Pharmacology Unit and "Interdisciplinary Center for the Study of Inflammation (ICSI),", Ferrara, Italy.

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http://dx.doi.org/10.1007/s11302-006-9019-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096665PMC
November 2006

Modulation of the Akt/Ras/Raf/MEK/ERK pathway by A₃ adenosine receptor.

Purinergic Signal 2006 Nov 26;2(4):627-32. Epub 2006 Jul 26.

Department of Clinical and Experimental Medicine, Pharmacology Section, University of Ferrara, Via Fossato di Mortara 17-19, 44100, Ferrara, Italy.

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http://link.springer.com/10.1007/s11302-006-9020-4
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http://dx.doi.org/10.1007/s11302-006-9020-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2096659PMC
November 2006

Adenosine modulates vascular endothelial growth factor expression via hypoxia-inducible factor-1 in human glioblastoma cells.

Biochem Pharmacol 2006 Jun 29;72(1):19-31. Epub 2006 Mar 29.

Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1016/j.bcp.2006.03.020DOI Listing
June 2006

Alteration of adenosine receptors in patients with chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2006 Feb 1;173(4):398-406. Epub 2005 Dec 1.

Department of Clinical and Experimental Medicine, Pharmacology Unit, Via Fossato di Mortara 17-19, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1164/rccm.200506-869OCDOI Listing
February 2006

Assessing quality of life of patients with advanced chronic obstructive pulmonary disease in the end of life.

J Palliat Care 2005 ;21(3):180-7

School of Nursing, The Hong Kong Polytechnic University, China.

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February 2006

The RNA-cleaving bipartite DNAzyme is a distinctive metalloenzyme.

Chembiochem 2006 Jan;7(1):98-105

Department of Molecular Biology and Biochemistry 1 and Department of Chemistry 2 Simon Fraser University, Burnaby, British Columbia V5A 1S6, Canada.

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http://dx.doi.org/10.1002/cbic.200500264DOI Listing
January 2006

Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors.

Biochem Pharmacol 2005 Nov 10;70(11):1601-12. Epub 2005 Oct 10.

Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, via Fossato di Mortara 17-19, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1016/j.bcp.2005.08.018DOI Listing
November 2005

Expression, pharmacological profile, and functional coupling of A2B receptors in a recombinant system and in peripheral blood cells using a novel selective antagonist radioligand, [3H]MRE 2029-F20.

Mol Pharmacol 2005 Jun 23;67(6):2137-47. Epub 2005 Mar 23.

Faculty of Medicine, Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, Via Fossato di Mortara 17-19, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1124/mol.104.009225DOI Listing
June 2005

Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells.

Clin Cancer Res 2004 Sep;10(17):5895-901

Department of Clinical and Experimental Medicine, Pharmacology Unit, Interdisciplinary Center for the Study of Inflammation, St. Anna Hospital, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-1134-03DOI Listing
September 2004

Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation.

Mol Pharmacol 2004 Mar;65(3):711-9

Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1124/mol.65.3.711DOI Listing
March 2004

A glance at adenosine receptors: novel target for antitumor therapy.

Pharmacol Ther 2003 Oct;100(1):31-48

Pharmacology Unit, Department of Clinical and Experimental Medicine, Via Fossato di Mortara 17-19, 44100, Ferrara, Italy.

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http://dx.doi.org/10.1016/s0163-7258(03)00084-6DOI Listing
October 2003

Pyrazolotriazolopyrimidine derivatives sensitize melanoma cells to the chemotherapic drugs: taxol and vindesine.

Biochem Pharmacol 2003 Sep;66(5):739-48

Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1016/s0006-2952(03)00400-3DOI Listing
September 2003

Adenosine receptors as mediators of both cell proliferation and cell death of cultured human melanoma cells.

J Invest Dermatol 2002 Oct;119(4):923-33

Department of Clinical and Experimental Medicine, Pharmacology Unit, University of Ferrara, Italy.

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http://dx.doi.org/10.1046/j.1523-1747.2002.00111.xDOI Listing
October 2002

Binding thermodynamics at the human A(3) adenosine receptor.

Biochem Pharmacol 2002 Jan;63(2):157-61

Department of Clinical and Experimental Medicine, Pharmacology Unit, Centro Nazionale di Eccellenza per lo Sviluppo di Metodologie Innovative per lo Studio ed il Trattamento delle Patologie Infiammatorie, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1016/s0006-2952(01)00825-5DOI Listing
January 2002