Edward L Huttlin

Edward L Huttlin

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Edward L Huttlin

Edward L Huttlin

Publications by authors named "Edward L Huttlin"

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Characterization of Plasmodium falciparum Atypical Kinase PfPK7 Dependent Phosphoproteome.

J Proteome Res 2018 06 30;17(6):2112-2123. Epub 2018 Apr 30.

Division of Molecular Biology and Microbiology, Burnett School of Biomedical Sciences , University of Central Florida , Orlando , Florida 32826 , United States.

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http://dx.doi.org/10.1021/acs.jproteome.8b00062DOI Listing
June 2018

DNAJC12: A molecular chaperone involved in proteostasis, PKU, biogenic amines metabolism and beyond?

Mol Genet Metab 2018 03 12;123(3):285-286. Epub 2018 Feb 12.

Reference Center for Inborn Errors of Metabolism, Robert Debré University Hospital, APHP, Paris 75019, France; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2018.01.006DOI Listing
March 2018

BioPlex Display: An Interactive Suite for Large-Scale AP-MS Protein-Protein Interaction Data.

J Proteome Res 2018 01 31;17(1):722-726. Epub 2017 Oct 31.

Department of Cell Biology, Harvard Medical School , Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00572DOI Listing
January 2018

Compositional Proteomics: Effects of Spatial Constraints on Protein Quantification Utilizing Isobaric Tags.

J Proteome Res 2018 01 15;17(1):590-599. Epub 2017 Dec 15.

Department of Cell Biology, Harvard Medical School , Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00699DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806995PMC
January 2018

Neutral Loss Is a Very Common Occurrence in Phosphotyrosine-Containing Peptides Labeled with Isobaric Tags.

J Proteome Res 2017 02 30;16(2):1069-1076. Epub 2016 Dec 30.

Department of Cell Biology, Harvard Medical School , Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/acs.jproteome.6b00487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479408PMC
February 2017

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

Nat Cell Biol 2015 Oct 21;17(10):1356-69. Epub 2015 Sep 21.

Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ncb3238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610257PMC
October 2015

Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

Mol Cell 2015 Sep 4;59(5):867-81. Epub 2015 Jun 4.

Department of Genetics, Harvard Medical School; Division of Genetics, Brigham and Women's Hospital; Howard Hughes Medical Institute, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560960PMC
September 2015

A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides.

Nat Biotechnol 2015 Jul 15;33(7):743-9. Epub 2015 Jun 15.

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.3267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515955PMC
July 2015

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation.

Genes Dev 2014 Feb;28(4):357-71

Institute for Research in Immunology and Cancer (IRIC), Université de Montréal, Montreal, Quebec H3C 3J7, Canada;

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http://dx.doi.org/10.1101/gad.231407.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937514PMC
February 2014

Candidate serum biomarkers for early intestinal cancer using 15N metabolic labeling and quantitative proteomics in the ApcMin/+ mouse.

J Proteome Res 2013 Sep 8;12(9):4152-66. Epub 2013 Aug 8.

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.

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http://dx.doi.org/10.1021/pr400467cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792563PMC
September 2013

Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility.

Mol Cell Biol 2013 Apr 11;33(8):1657-70. Epub 2013 Feb 11.

Institute for Research in Immunology and Cancer, Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1128/MCB.01353-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3624252PMC
April 2013

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.

Nature 2013 Apr 17;496(7445):372-6. Epub 2013 Mar 17.

Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nature12043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641819PMC
April 2013

Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses.

Anal Chem 2012 Sep 20;84(17):7469-78. Epub 2012 Aug 20.

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.

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http://dx.doi.org/10.1021/ac301572tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715028PMC
September 2012

Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics.

Mol Cell Proteomics 2011 Dec 13;10(12):M111.009910. Epub 2011 Sep 13.

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1074/mcp.M111.009910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237076PMC
December 2011

Correct interpretation of comprehensive phosphorylation dynamics requires normalization by protein expression changes.

Mol Cell Proteomics 2011 Aug 7;10(8):M111.009654. Epub 2011 May 7.

Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1074/mcp.M111.009654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149096PMC
August 2011

A large-scale method to measure absolute protein phosphorylation stoichiometries.

Nat Methods 2011 Jul 3;8(8):677-83. Epub 2011 Jul 3.

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nmeth.1636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146562PMC
July 2011

Democratization and integration of genomic profiling tools.

Methods Mol Biol 2009 ;553:373-93

Department of Biochemistry, UW Biotechnology Center, University of Wisconsin-Madison, Madison, WI, USA.

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http://link.springer.com/10.1007/978-1-60327-563-7_20
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http://dx.doi.org/10.1007/978-1-60327-563-7_20DOI Listing
January 2010

Matching isotopic distributions from metabolically labeled samples.

Bioinformatics 2008 Jul;24(13):i339-47

Department of Computer Sciences, University of Wisconsin, Madison, WI, USA.

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http://dx.doi.org/10.1093/bioinformatics/btn190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2718665PMC
July 2008

Stable isotope assisted assignment of elemental compositions for metabolomics.

Anal Chem 2007 Sep 21;79(18):6912-21. Epub 2007 Aug 21.

Department of Biochemistry, University of Wisconsin, 433 Babcock Drive, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1021/ac070346tDOI Listing
September 2007

Comparison of full versus partial metabolic labeling for quantitative proteomics analysis in Arabidopsis thaliana.

Mol Cell Proteomics 2007 May 9;6(5):860-81. Epub 2007 Feb 9.

Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://www.mcponline.org/content/6/5/860.full.pdf
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http://www.mcponline.org/cgi/doi/10.1074/mcp.M600347-MCP200
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http://dx.doi.org/10.1074/mcp.M600347-MCP200DOI Listing
May 2007

Implications of 15N-metabolic labeling for automated peptide identification in Arabidopsis thaliana.

Proteomics 2007 Apr;7(8):1279-92

Department of Comparative Biosciences, University of Wisconsin, Madison, WI, USA.

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http://doi.wiley.com/10.1002/pmic.200600832
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http://dx.doi.org/10.1002/pmic.200600832DOI Listing
April 2007

A transcriptome-based characterization of habituation in plant tissue culture.

Plant Physiol 2006 Apr 17;140(4):1255-78. Epub 2006 Feb 17.

University of Wisconsin Biotechnology Center and Department of Biochemistry, Madison, Wisconsin 53706, USA.

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http://www.plantphysiol.org/cgi/doi/10.1104/pp.105.076059
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http://dx.doi.org/10.1104/pp.105.076059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1435795PMC
April 2006