Edward Flynn

Edward Flynn

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Edward Flynn

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Development of advanced signal processing and source imaging methods for superparamagnetic relaxometry.

Authors:
Ming-Xiong Huang Bill Anderson Charles W Huang Gerd J Kunde Erika C Vreeland Jeffrey W Huang Andrei N Matlashov Todor Karaulanov Christopher P Nettles Andrew Gomez Kayla Minser Caroline Weldon Giulio Paciotti Michael Harsh Roland R Lee Edward R Flynn

Phys Med Biol 2017 02 10;62(3):734-757. Epub 2017 Jan 10.

Radiology and Research Services, VA San Diego Healthcare System, San Diego, CA, USA. Department of Radiology, University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1088/1361-6560/aa553bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797703PMC
February 2017

Breaking up prolonged sitting time with walking does not affect appetite or gut hormone concentrations but does induce an energy deficit and suppresses postprandial glycaemia in sedentary adults.

Authors:
Daniel P Bailey David R Broom Bryna C R Chrismas Lee Taylor Edward Flynn John Hough

Appl Physiol Nutr Metab 2016 Mar 14;41(3):324-31. Epub 2015 Dec 14.

a Institute for Sport and Physical Activity Research, Department of Sport Science and Physical Activity, University of Bedfordshire, Polhill Avenue, Bedford, MK41 9EA, UK.

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http://dx.doi.org/10.1139/apnm-2015-0462DOI Listing
March 2016

Magnetic relaxometry as applied to sensitive cancer detection and localization.

Authors:
Leyma P De Haro Todor Karaulanov Erika C Vreeland Bill Anderson Helen J Hathaway Dale L Huber Andrei N Matlashov Christopher P Nettles Andrew D Price Todd C Monson Edward R Flynn

Biomed Tech (Berl) 2015 Oct;60(5):445-55

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http://dx.doi.org/10.1515/bmt-2015-0053DOI Listing
October 2015

Commensal microbiota stimulate systemic neutrophil migration through induction of serum amyloid A.

Authors:
Michelle Kanther Sarah Tomkovich Sun Xiaolun Melinda R Grosser Jaseol Koo Edward J Flynn Christian Jobin John F Rawls

Cell Microbiol 2014 Jul 24;16(7):1053-67. Epub 2014 Jan 24.

Department of Cell Biology and Physiology, University of North Carolina, Chapel Hill, NC, 27599, USA.

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http://doi.wiley.com/10.1111/cmi.12257
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http://dx.doi.org/10.1111/cmi.12257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364439PMC
July 2014

The role of genetic polymorphisms regulating vitamin D levels in rheumatoid arthritis outcome: a Mendelian randomisation approach.

Authors:
Sebastien Viatte Annie Yarwood Kate McAllister Shibeb Al-Mudhaffer Bo Fu Edward Flynn Deborah P M Symmons Adam Young Anne Barton

Ann Rheum Dis 2014 Jul 20;73(7):1430-3. Epub 2014 Mar 20.

Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust, Manchester Academic Health Sciences Centre, Manchester, UK.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2013-20497
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http://dx.doi.org/10.1136/annrheumdis-2013-204972DOI Listing
July 2014

Modeling the efficiency of a magnetic needle for collecting magnetic cells.

Authors:
Kimberly S Butler Natalie L Adolphi H C Bryant Debbie M Lovato Richard S Larson Edward R Flynn

Phys Med Biol 2014 Jul 29;59(13):3319-35. Epub 2014 May 29.

Department of Pathology, University of New Mexico Health Sciences Center, 1 University of New Mexico, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1088/0031-9155/59/13/3319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084562PMC
July 2014

Development of antibody-tagged nanoparticles for detection of transplant rejection using biomagnetic sensors.

Authors:
Kimberly S Butler Debbie M Lovato Natalie L Adolphi Robert Belfon Danielle L Fegan Todd C Monson Helen J Hathaway Dale L Huber T E Tessier H C Bryant Edward R Flynn Richard S Larson

Cell Transplant 2013 12;22(10):1943-54. Epub 2012 Oct 12.

Department of Pathology, University of New Mexico, and Cancer Research and Treatment Center, Albuquerque, NM, USA.

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http://dx.doi.org/10.3727/096368912X657963DOI Listing
April 2014

Identification of the tyrosine-protein phosphatase non-receptor type 2 as a rheumatoid arthritis susceptibility locus in europeans.

Authors:
Joanna E Cobb Darren Plant Edward Flynn Meriem Tadjeddine Philippe Dieudé François Cornélis Lisbeth Ärlestig Solbritt Rantapää Dahlqvist George Goulielmos Dimitrios T Boumpas Prodromos Sidiropoulos Sophine B Krintel Lykke M Ørnbjerg Merete L Hetland Lars Klareskog Thomas Haeupl Andrew Filer Christopher D Buckley Karim Raza Torsten Witte Reinhold E Schmidt Oliver FitzGerald Douglas Veale Stephen Eyre Jane Worthington

PLoS One 2013 20;8(6):e66456. Epub 2013 Jun 20.

Arthritis Research UK Epidemiology Unit, Central Manchester Foundation Trust, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066456PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688762PMC
February 2014

Investigation of C reactive protein gene polymorphisms as predictors of cardiovascular mortality in inflammatory polyarthritis: results from the Norfolk Arthritis Register.

Authors:
Ibrahim Ibrahim Darren Plant Mark Lunt Suzanne Verstappen Edward Flynn Deborah Symmons Anne Barton

Ann Rheum Dis 2013 Aug 18;72(8):1429-30. Epub 2013 Apr 18.

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http://dx.doi.org/10.1136/annrheumdis-2012-202920DOI Listing
August 2013

Investigation of rheumatoid arthritis genetic susceptibility markers in the early rheumatoid arthritis study further replicates the TRAF1 association with radiological damage.

Authors:
Sebastien Viatte Darren Plant Mark Lunt Bo Fu Edward Flynn Ben J Parker James Galloway Csilla Solymossy Jane Worthington Deborah P M Symmons Josh J Dixey Adam Young Anne Barton

J Rheumatol 2013 Feb 15;40(2):144-56. Epub 2012 Dec 15.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://www.jrheum.org/cgi/doi/10.3899/jrheum.121034
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http://dx.doi.org/10.3899/jrheum.121034DOI Listing
February 2013

Imaging of Her2-targeted magnetic nanoparticles for breast cancer detection: comparison of SQUID-detected magnetic relaxometry and MRI.

Authors:
Natalie L Adolphi Kimberly S Butler Debbie M Lovato T E Tessier Jason E Trujillo Helen J Hathaway Danielle L Fegan Todd C Monson Tyler E Stevens Dale L Huber Jaivijay Ramu Michelle L Milne Stephen A Altobelli Howard C Bryant Richard S Larson Edward R Flynn

Contrast Media Mol Imaging 2012 May-Jun;7(3):308-19

Department of Biochemistry and Molecular Biology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1002/cmmi.499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883306PMC
December 2012

Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease.

Authors:
Sebastien Viatte Edward Flynn Mark Lunt Joanne Barnes Madeleine Singwe-Ngandeu Sylvette Bas Anne Barton Cem Gabay

Arthritis Res Ther 2012 Nov 3;14(6):R239. Epub 2012 Nov 3.

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http://dx.doi.org/10.1186/ar4082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674592PMC
November 2012

Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort.

Authors:
Darren Plant Ibrahim Ibrahim Mark Lunt Stephen Eyre Edward Flynn Kimme L Hyrich Ann W Morgan Anthony G Wilson John D Isaacs Anne Barton

Arthritis Res Ther 2012 Oct 7;14(5):R214. Epub 2012 Oct 7.

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http://dx.doi.org/10.1186/ar4052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580526PMC
October 2012

Comprehensive assessment of rheumatoid arthritis susceptibility loci in a large psoriatic arthritis cohort.

Authors:
John Bowes Pauline Ho Edward Flynn Faisal Ali Helena Marzo-Ortega Laura C Coates Richard B Warren Ross McManus Anthony W Ryan David Kane Eleanor Korendowych Neil McHugh Oliver FitzGerald Jonathon Packham Ann W Morgan Ian N Bruce Anne Barton

Ann Rheum Dis 2012 Aug 10;71(8):1350-4. Epub 2012 Feb 10.

Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, UK.

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2011-20080
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http://dx.doi.org/10.1136/annrheumdis-2011-200802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396450PMC
August 2012

Magnetic Relaxometry with an Atomic Magnetometer and SQUID Sensors on Targeted Cancer Cells.

Authors:
Cort Johnson Natalie L Adolphi Kimberly L Butler Lovato Debbie M Richard Larson Peter D D Schwindt Edward R Flynn

J Magn Magn Mater 2012 Aug;324(17):2613-2619

Sandia National Laboratories, P.O. Box 5800, Albuquerque, New Mexico 87185.

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http://dx.doi.org/10.1016/j.jmmm.2012.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3389787PMC
August 2012

LRP1-dependent endocytic mechanism governs the signaling output of the bmp system in endothelial cells and in angiogenesis.

Authors:
Xinchun Pi Christopher E Schmitt Liang Xie Andrea L Portbury Yaxu Wu Pamela Lockyer Laura A Dyer Martin Moser Guojun Bu Edward J Flynn Suk-Won Jin Cam Patterson

Circ Res 2012 Aug 9;111(5):564-74. Epub 2012 Jul 9.

Health Care Entrepreneurship, UNC Center for Heart and Vascular Care, Division of Cardiology, 8200 Medical Biomolecular Research Building, Chapel Hill, NC 27599-7126, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.112.274597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495066PMC
August 2012

Investigation of rheumatoid arthritis susceptibility loci in juvenile idiopathic arthritis confirms high degree of overlap.

Authors:
Anne Hinks Joanna Cobb Marc Sudman Stephen Eyre Paul Martin Edward Flynn Jonathon Packham Anne Barton Jane Worthington Carl D Langefeld David N Glass Susan D Thompson Wendy Thomson

Ann Rheum Dis 2012 Jul 31;71(7):1117-21. Epub 2012 Jan 31.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/annrheumdis-2011-200814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375583PMC
July 2012

Investigation of IL1, VEGF, PPARG and MEFV genes in psoriatic arthritis susceptibility.

Authors:
John Bowes Pauline Ho Edward Flynn Salma Salah Neil McHugh Oliver FitzGerald Jonathan Packham Ann W Morgan Philip S Helliwell Ian N Bruce Anne Barton

Ann Rheum Dis 2012 Feb 28;71(2):313-4. Epub 2011 Jul 28.

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http://dx.doi.org/10.1136/ard.2011.154690DOI Listing
February 2012

Detection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field sensors.

Authors:
Helen J Hathaway Kimberly S Butler Natalie L Adolphi Debbie M Lovato Robert Belfon Danielle Fegan Todd C Monson Jason E Trujillo Trace E Tessier Howard C Bryant Dale L Huber Richard S Larson Edward R Flynn

Breast Cancer Res 2011 Nov 3;13(5):R108. Epub 2011 Nov 3.

Department of Cell Biology & Physiology, University of New Mexico School of Medicine, MSC08 4750, 1 University of New Mexico, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1186/bcr3050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3262221PMC
November 2011

Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis.

Authors:
John Bowes Gisela Orozco Edward Flynn Pauline Ho Rasha Brier Helena Marzo-Ortega Laura Coates Ross McManus Anthony W Ryan David Kane Eleanor Korendowych Neil McHugh Oliver FitzGerald Jonathan Packham Ann W Morgan Ian N Bruce Anne Barton

Ann Rheum Dis 2011 Sep 29;70(9):1641-4. Epub 2011 May 29.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/ard.2011.150102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147229PMC
September 2011

Microbial colonization induces dynamic temporal and spatial patterns of NF-κB activation in the zebrafish digestive tract.

Authors:
Michelle Kanther Xiaolun Sun Marcus Mühlbauer Lantz C Mackey Edward J Flynn Michel Bagnat Christian Jobin John F Rawls

Gastroenterology 2011 Jul 24;141(1):197-207. Epub 2011 Mar 24.

Department of Cell and Molecular Physiology, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S001650851100385
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http://dx.doi.org/10.1053/j.gastro.2011.03.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164861PMC
July 2011

Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris.

Authors:
John Bowes Steve Eyre Edward Flynn Pauline Ho Salma Salah Richard B Warren Helena Marzo-Ortega Laura Coates Ross McManus Anthony W Ryan David Kane Eleanor Korendowych Neil McHugh Oliver FitzGerald Jonathan Packham Ann W Morgan Christopher E M Griffiths Ian N Bruce Jane Worthington Anne Barton

Ann Rheum Dis 2011 Jun 23;70(6):1016-9. Epub 2011 Feb 23.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/ard.2010.143123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086035PMC
June 2011

Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease.

Authors:
Stephen Eyre Anne Hinks John Bowes Edward Flynn Paul Martin Anthony G Wilson Ann W Morgan Paul Emery Sophia Steer Lynne J Hocking David M Reid Pille Harrison Paul Wordsworth Wendy Thomson Jane Worthington Anne Barton

Arthritis Res Ther 2010 20;12(5):R175. Epub 2010 Sep 20.

Arthritis Research UK, Epidemiology Unit, Stopford Building, Oxford Road, The University of Manchester, Manchester M13 9PT, UK.

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http://arthritis-research.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/ar3139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2991006PMC
March 2011

Magnetic Properties of Nanoparticles Useful for SQUID Relaxometry in Biomedical Applications.

Authors:
H C Bryant Natalie L Adolphi Dale L Huber Danielle L Fegan Todd C Monson Trace E Tessier Edward R Flynn

J Magn Magn Mater 2011 Mar;323(6):767-774

Senior Scientific LLC, 11109 Country Club NE, Albuquerque, New Mexico, 87111.

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http://dx.doi.org/10.1016/j.jmmm.2010.10.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3079235PMC
March 2011

The role of rheumatoid arthritis genetic susceptibility markers in the prediction of erosive disease in patients with early inflammatory polyarthritis: results from the Norfolk Arthritis Register.

Authors:
Darren Plant Wendy Thomson Mark Lunt Edward Flynn Paul Martin Steven Eyre Tracey Farragher Diane Bunn Jane Worthington Deborah Symmons Anne Barton

Rheumatology (Oxford) 2011 Jan 10;50(1):78-84. Epub 2010 Mar 10.

ARC Epidemiology Unit, Manchester Academic Health Sciences Centre, The University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/rheumatology/keq032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999953PMC
January 2011

Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP1 with the enthesitis related arthritis subtype and IL23R with juvenile psoriatic arthritis.

Authors:
Anne Hinks Paul Martin Edward Flynn Steve Eyre Jon Packham Anne Barton Jane Worthington Wendy Thomson

Arthritis Res Ther 2011 Jan 31;13(1):R12. Epub 2011 Jan 31.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, Stopford Building, Oxford Road, The University of Manchester, Manchester M139PT, UK.

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http://arthritis-research.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/ar3235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3241356PMC
January 2011

Variants in linkage disequilibrium with the late cornified envelope gene cluster deletion are associated with susceptibility to psoriatic arthritis.

Authors:
John Bowes Edward Flynn Pauline Ho Batool Aly Ann W Morgan Helena Marzo-Ortega Laura Coates Ross McManus Anthony W Ryan David Kane Eleanor Korendowych Neil McHugh Oliver FitzGerald Jonathan Packham Ian N Bruce Anne Barton

Ann Rheum Dis 2010 Dec 19;69(12):2199-203. Epub 2010 Jul 19.

Arthritis Research UK Epidemiology Unit, Stopford Building, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1136/ard.2010.130575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002763PMC
December 2010

Investigation of type 1 diabetes and coeliac disease susceptibility loci for association with juvenile idiopathic arthritis.

Authors:
Anne Hinks Paul Martin Edward Flynn Steve Eyre Jon Packham Anne Barton Jane Worthington Wendy Thomson

Ann Rheum Dis 2010 Dec 20;69(12):2169-72. Epub 2010 Jul 20.

Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, Stopford Building, The University of Manchester, Manchester, UK.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2009.126938
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http://dx.doi.org/10.1136/ard.2009.126938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002762PMC
December 2010

Characterization of single-core magnetite nanoparticles for magnetic imaging by SQUID relaxometry.

Authors:
Natalie L Adolphi Dale L Huber Howard C Bryant Todd C Monson Danielle L Fegan Jitkang Lim Jason E Trujillo Trace E Tessier Debbie M Lovato Kimberly S Butler Paula P Provencio Helen J Hathaway Sara A Majetich Richard S Larson Edward R Flynn

Phys Med Biol 2010 Oct 21;55(19):5985-6003. Epub 2010 Sep 21.

Department of Biochemistry and Molecular Biology, University of New Mexico, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1088/0031-9155/55/19/023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883308PMC
October 2010

Confirmation of association of the REL locus with rheumatoid arthritis susceptibility in the UK population.

Authors:
Stephen Eyre Anne Hinks Edward Flynn Paul Martin Anthony G Wilson James R Maxwell Ann W Morgan Paul Emery Sophia Steer Lynne J Hocking David M Reid Pille Harrison Paul Wordsworth Wendy Thomson Jane Worthington Anne Barton

Ann Rheum Dis 2010 Aug 27;69(8):1572-3. Epub 2009 Nov 27.

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http://ard.bmj.com/cgi/doi/10.1136/ard.2009.122887
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http://dx.doi.org/10.1136/ard.2009.122887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3009391PMC
August 2010

Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers.

Authors:
Darren Plant Edward Flynn Hamdi Mbarek Philippe Dieudé François Cornelis Lisbeth Arlestig Solbritt Rantapää Dahlqvist George Goulielmos Dimitrios T Boumpas Prodromos Sidiropoulos Julia S Johansen Lykke M Ørnbjerg Merete Lund Hetland Lars Klareskog Andrew Filer Christopher D Buckley Karim Raza Torsten Witte Reinhold E Schmidt Jane Worthington

Ann Rheum Dis 2010 Aug 24;69(8):1548-53. Epub 2010 May 24.

arc-Epidemiology Unit, Stopford Building, The University of Manchester, Manchester M13 9PT, UK.

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http://ard.bmj.com/content/69/8/1548.full.pdf
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http://ard.bmj.com/cgi/doi/10.1136/ard.2009.121020
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http://dx.doi.org/10.1136/ard.2009.121020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938898PMC
August 2010

No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort.

Authors:
Stephen Eyre Edward Flynn Paul Martin Anne Hinks Anthony G Wilson Ann W Morgan Paul Emery Sophia Steer Lynne J Hocking David M Reid Pille Harrison Paul Wordsworth Wendy Thomson Jane Worthington Anne Barton

Ann Rheum Dis 2010 Jul 11;69(7):1407-8. Epub 2009 Nov 11.

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http://dx.doi.org/10.1136/ard.2009.120428DOI Listing
July 2010

Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis.

Authors:
Anne Hinks Steve Eyre Xiayi Ke Anne Barton Paul Martin Edward Flynn Jon Packham Jane Worthington Wendy Thomson

Ann Rheum Dis 2010 Jun 11;69(6):1049-53. Epub 2009 Aug 11.

Stopford Building, Oxford Road, The University of Manchester, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1136/ard.2009.110650DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935325PMC
June 2010

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.

Authors:
Eli A Stahl Soumya Raychaudhuri Elaine F Remmers Gang Xie Stephen Eyre Brian P Thomson Yonghong Li Fina A S Kurreeman Alexandra Zhernakova Anne Hinks Candace Guiducci Robert Chen Lars Alfredsson Christopher I Amos Kristin G Ardlie Anne Barton John Bowes Elisabeth Brouwer Noel P Burtt Joseph J Catanese Jonathan Coblyn Marieke J H Coenen Karen H Costenbader Lindsey A Criswell J Bart A Crusius Jing Cui Paul I W de Bakker Philip L De Jager Bo Ding Paul Emery Edward Flynn Pille Harrison Lynne J Hocking Tom W J Huizinga Daniel L Kastner Xiayi Ke Annette T Lee Xiangdong Liu Paul Martin Ann W Morgan Leonid Padyukov Marcel D Posthumus Timothy R D J Radstake David M Reid Mark Seielstad Michael F Seldin Nancy A Shadick Sophia Steer Paul P Tak Wendy Thomson Annette H M van der Helm-van Mil Irene E van der Horst-Bruinsma C Ellen van der Schoot Piet L C M van Riel Michael E Weinblatt Anthony G Wilson Gert Jan Wolbink B Paul Wordsworth Cisca Wijmenga Elizabeth W Karlson Rene E M Toes Niek de Vries Ann B Begovich Jane Worthington Katherine A Siminovitch Peter K Gregersen Lars Klareskog Robert M Plenge

Nat Genet 2010 Jun 9;42(6):508-14. Epub 2010 May 9.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243840PMC
June 2010

Association of a rheumatoid arthritis susceptibility variant at the CCL21 locus with premature mortality in inflammatory polyarthritis patients.

Authors:
Tracey M Farragher Darren Plant Edward Flynn Steve Eyre Diane Bunn Wendy Thomson Deborah Symmons Anne Barton

Arthritis Care Res (Hoboken) 2010 May;62(5):676-82

arc Epidemiology Unit, The University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1002/acr.20208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936115PMC
May 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk.

Authors:
Soumya Raychaudhuri Brian P Thomson Elaine F Remmers Stephen Eyre Anne Hinks Candace Guiducci Joseph J Catanese Gang Xie Eli A Stahl Robert Chen Lars Alfredsson Christopher I Amos Kristin G Ardlie Anne Barton John Bowes Noel P Burtt Monica Chang Jonathan Coblyn Karen H Costenbader Lindsey A Criswell J Bart A Crusius Jing Cui Phillip L De Jager Bo Ding Paul Emery Edward Flynn Pille Harrison Lynne J Hocking Tom W J Huizinga Daniel L Kastner Xiayi Ke Fina A S Kurreeman Annette T Lee Xiangdong Liu Yonghong Li Paul Martin Ann W Morgan Leonid Padyukov David M Reid Mark Seielstad Michael F Seldin Nancy A Shadick Sophia Steer Paul P Tak Wendy Thomson Annette H M van der Helm-van Mil Irene E van der Horst-Bruinsma Michael E Weinblatt Anthony G Wilson Gert Jan Wolbink Paul Wordsworth David Altshuler Elizabeth W Karlson Rene E M Toes Niek de Vries Ann B Begovich Katherine A Siminovitch Jane Worthington Lars Klareskog Peter K Gregersen Mark J Daly Robert M Plenge

Nat Genet 2009 Dec 8;41(12):1313-8. Epub 2009 Nov 8.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142887PMC
December 2009

Enhanced leukemia cell detection using a novel magnetic needle and nanoparticles.

Authors:
Jason E Jaetao Kimberly S Butler Natalie L Adolphi Debbie M Lovato Howard C Bryant Ian Rabinowitz Stuart S Winter Trace E Tessier Helen J Hathaway Christian Bergemann Edward R Flynn Richard S Larson

Cancer Res 2009 Nov 6;69(21):8310-6. Epub 2009 Oct 6.

Department of Pathology, University of New Mexico and Cancer Research and Treatment Center, Albuquerque, New Mexico 87131, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-1083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783727PMC
November 2009

Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio).

Authors:
Edward J Flynn Chad M Trent John F Rawls

J Lipid Res 2009 Aug 14;50(8):1641-52. Epub 2009 Apr 14.

Department of Cell and Molecular Physiology, University of North Carolina, Chapel Hill, NC 27599-7545, USA.

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http://dx.doi.org/10.1194/jlr.M800590-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724053PMC
August 2009

Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes.

Authors:
Anne Barton Steve Eyre Xiayi Ke Anne Hinks John Bowes Edward Flynn Paul Martin Anthony G Wilson Ann W Morgan Paul Emery Sophia Steer Lynne J Hocking David M Reid Pille Harrison Paul Wordsworth Wendy Thomson Jane Worthington

Hum Mol Genet 2009 Jul 9;18(13):2518-22. Epub 2009 Apr 9.

University of Manchester, Manchester, UK.

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http://hmg.oxfordjournals.org/content/18/13/2518.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddp177
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http://dx.doi.org/10.1093/hmg/ddp177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694689PMC
July 2009

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.

Authors:
Gisela Orozco Anne Hinks Steve Eyre Xiayi Ke Laura J Gibbons John Bowes Edward Flynn Paul Martin Anthony G Wilson Deborah E Bax Ann W Morgan Paul Emery Sophia Steer Lynne Hocking David M Reid Paul Wordsworth Pille Harrison Wendy Thomson Anne Barton Jane Worthington

Hum Mol Genet 2009 Jul 5;18(14):2693-9. Epub 2009 May 5.

arc-Epidemiology Unit, Stopford Building, The University of Manchester, Manchester M13 9PT, UK.

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http://dx.doi.org/10.1093/hmg/ddp193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701332PMC
July 2009

Characterization of magnetite nanoparticles for SQUID-relaxometry and magnetic needle biopsy.

Authors:
Natalie L Adolphi Dale L Huber Jason E Jaetao Howard C Bryant Debbie M Lovato Danielle L Fegan Eugene L Venturini Todd C Monson Trace E Tessier Helen J Hathaway Christian Bergemann Richard S Larson Edward R Flynn

J Magn Magn Mater 2009 May;321(10):1459-1464

Senior Scientific, LLC, 11109 Country Club NE, Albuquerque, New Mexico 87111 USA.

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http://dx.doi.org/10.1016/j.jmmm.2009.02.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734090PMC
May 2009

Magnetic needles and superparamagnetic cells.

Authors:
H C Bryant D A Sergatskov Debbie Lovato Natalie L Adolphi Richard S Larson Edward R Flynn

Phys Med Biol 2007 Jul 8;52(14):4009-25. Epub 2007 Jun 8.

Senior Scientific, LLC, 11109 Country Club Dr. NE, Albuquerque, NM 87111, USA.

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http://dx.doi.org/10.1088/0031-9155/52/14/001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2041887PMC
July 2007

Use of a SQUID array to detect T-cells with magnetic nanoparticles in determining transplant rejection.

Authors:
Edward R Flynn H C Bryant Christian Bergemann Richard S Larson Debbie Lovato Dmitri A Sergatskov

J Magn Magn Mater 2007 Apr;311(1):429-435

Senior Scientific, 11109 Country Club NE, Albuquerque, NM 87111, USA.

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http://dx.doi.org/10.1016/j.jmmm.2006.10.1148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139906PMC
April 2007

Incorporation of the genetic control of alcohol dehydrogenase into a physiologically based pharmacokinetic model for ethanol in humans.

Authors:
Lester G Sultatos Gina M Pastino Clint A Rosenfeld Edward J Flynn

Toxicol Sci 2004 Mar 12;78(1):20-31. Epub 2004 Jan 12.

Department of Pharmacology and Physiology, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, New Jersey 07103, USA.

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http://dx.doi.org/10.1093/toxsci/kfh057DOI Listing
March 2004

Federal statutes--constitutional law--Medicaid Act requires states to fund all medically necessary abortions subject to Hyde Amendment.

Authors:
Edward C Flynn

Notre Dame Lawyer 1980 Feb;55(3):412-23

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February 1980