Publications by authors named "Edward E Tredget"

100Publications

Orbital compartment syndrome following major burn resuscitation: a case series and survey of practice patterns.

J Burn Care Res 2020 Aug 20. Epub 2020 Aug 20.

Division of Plastic & Reconstructive Surgery, University of Toronto, Toronto, ON.

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http://dx.doi.org/10.1093/jbcr/iraa126DOI Listing
August 2020

A Preliminary Report of the Biochemical and Clinical Effects of 1,4-Diaminobutane on Prevention of Human Hypertrophic Scars.

Plast Reconstr Surg 2020 01;145(1):76e-84e

Winnipeg, Manitoba; and Edmonton, Alberta, Canada From the Section of Plastic Surgery, Department of Surgery, University of Manitoba; and the Division of Plastic Surgery, Department of Surgery and Critical Care Medicine, University of Alberta.

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http://dx.doi.org/10.1097/PRS.0000000000006413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940031PMC
January 2020

Advanced Training and Job Satisfaction Among Recent Canadian Plastic Surgery Graduates.

Plast Surg (Oakv) 2019 Aug 31;27(3):223-229. Epub 2019 Mar 31.

Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1177/2292550319826089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696863PMC
August 2019

Ivy Loop Wiring: A Useful Form of Endotracheal Tube Stabilization in Burn Patients.

Plast Surg (Oakv) 2017 Aug 25;25(3):175-178. Epub 2017 Jul 25.

Division of Plastic Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1177/2292550317716123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626208PMC
August 2017

Platelet-derived growth factor receptor beta identifies mesenchymal stem cells with enhanced engraftment to tissue injury and pro-angiogenic property.

Cell Mol Life Sci 2018 02 19;75(3):547-561. Epub 2017 Sep 19.

The Shenzhen Key Laboratory of Health Sciences and Technology, Graduate School at Shenzhen, Tsinghua University, L406A, Tsinghua Campus, The University Town, Shenzhen, 518055, China.

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http://dx.doi.org/10.1007/s00018-017-2641-7DOI Listing
February 2018

Distinctively Expressed Cytokines by Three Different Inflammation Cells and Their Interaction with Keratinocytes in Wound Healing.

Inflammation 2017 Dec;40(6):2151-2162

The Shenzhen Key Laboratory of Health Sciences and Technology, Graduate School at Shenzhen, Tsinghua University, Shenzhen, China.

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http://dx.doi.org/10.1007/s10753-017-0655-9DOI Listing
December 2017

Transplanting Human Skin Grafts onto Nude Mice to Model Skin Scars.

Methods Mol Biol 2017 ;1627:65-80

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1007/978-1-4939-7113-8_5DOI Listing
May 2018

Alternatively activated macrophages derived from THP-1 cells promote the fibrogenic activities of human dermal fibroblasts.

Wound Repair Regen 2017 05 27;25(3):377-388. Epub 2017 Apr 27.

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1111/wrr.12532DOI Listing
May 2017

Biological Principles of Scar and Contracture.

Hand Clin 2017 05 1;33(2):277-292. Epub 2017 Mar 1.

Department of Surgery, University of Alberta, 2D2.28 WMHSC, 8440-112 Street Northwest, Edmonton, Alberta T6G 2B7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.hcl.2016.12.004DOI Listing
May 2017

Scar Management Following Burn Injury.

J Burn Care Res 2017 May/Jun;38(3):146-147

From the *Department of Surgery, University of Alberta-Edmonton, Edmonton, Alberta, Canada; †Firefighters' Burn and Surgical Research Laboratory, MedStar Health Research Institute, Washington, DC; ‡The Burn Center, MedStar Washington Hospital Center, Washington, DC; §Massachusetts General Hospital, Shriners Hospitals for Children®-Boston, Spaulding, Boston, MA; and ‖Rehabilitation Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/BCR.0000000000000548DOI Listing
February 2018

Important Developments in Burn Care.

Plast Reconstr Surg 2017 Jan;139(1):120e-138e

Toronto, Ontario, and Edmonton, Alberta, Canada From the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Toronto; and the Divisions of Plastic and Reconstructive Surgery and Critical Care, Department of Surgery, University of Alberta.

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http://dx.doi.org/10.1097/PRS.0000000000002908DOI Listing
January 2017

Serum Decorin, Interleukin-1β, and Transforming Growth Factor-β Predict Hypertrophic Scarring Postburn.

J Burn Care Res 2016 Nov/Dec;37(6):356-366

From the *Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada; †Wound Healing Research Group, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Canada; and ‡Critical Care, Department of Surgery, University of Alberta Hospital, Edmonton, Canada.

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http://dx.doi.org/10.1097/BCR.0000000000000271DOI Listing
March 2018

The molecular basis of hypertrophic scars.

Burns Trauma 2016 21;4. Epub 2016 Jan 21.

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta Canada ; Division of Plastic Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta Canada.

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http://dx.doi.org/10.1186/s41038-015-0026-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963951PMC
August 2016

Hair Follicle and Sebaceous Gland De Novo Regeneration With Cultured Epidermal Stem Cells and Skin-Derived Precursors.

Stem Cells Transl Med 2016 12 25;5(12):1695-1706. Epub 2016 Jul 25.

Shenzhen Key Laboratory of Health Sciences and Technology, Graduate School at Shenzhen, Tsinghua University, Beijing, People's Republic of China

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http://dx.doi.org/10.5966/sctm.2015-0397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5189649PMC
December 2016

A Novel Nude Mouse Model of Hypertrophic Scarring Using Scratched Full Thickness Human Skin Grafts.

Adv Wound Care (New Rochelle) 2016 Jul;5(7):299-313

Wound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, Canada.; Divisions of Plastic and Reconstructive Surgery and Critical Care, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1089/wound.2015.0670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900225PMC
July 2016

Modified Meek Micrografting Technique for Wound Coverage in Extensive Burn Injuries.

J Burn Care Res 2016 Sep-Oct;37(5):305-13

From the *Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, †Division of Critical Care Medicine, and ‡Firefighters' Burn Treatment Unit, Department of Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1097/BCR.0000000000000244DOI Listing
March 2018

Self-assembling peptide hydrogel scaffolds support stem cell-based hair follicle regeneration.

Nanomedicine 2016 10 9;12(7):2115-2125. Epub 2016 Jun 9.

The Shenzhen Key Laboratory of Health Sciences and Technology, Graduate School at Shenzhen, Tsinghua University, China; Tsinghua-Berkeley Shenzhen Institute (TBSI), Tsinghua University, China. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2016.05.021DOI Listing
October 2016

Synergistic effect of vitamin D and low concentration of transforming growth factor beta 1, a potential role in dermal wound healing.

Burns 2016 Sep 22;42(6):1277-86. Epub 2016 May 22.

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, 2D2.28 WMC, 8440-112 Street, Edmonton, Alberta, Canada T6G 2B7; Division of Critical Care Medicine, Department of Surgery, University of Alberta, 2D2.28 WMC, 8440-112 Street, Edmonton, Alberta, Canada T6G 2B7. Electronic address:

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http://dx.doi.org/10.1016/j.burns.2016.03.009DOI Listing
September 2016

Systemic depletion of macrophages in the subacute phase of wound healing reduces hypertrophic scar formation.

Wound Repair Regen 2016 07 14;24(4):644-56. Epub 2016 Jun 14.

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery.

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http://dx.doi.org/10.1111/wrr.12442DOI Listing
July 2016

Morphologic and Histologic Comparison of Hypertrophic Scar in Nude Mice, T-Cell Receptor, and Recombination Activating Gene Knockout Mice.

Plast Reconstr Surg 2015 Dec;136(6):1192-204

Ottawa and Hamilton, Ontario, and Edmonton, Alberta, Canada From the Division of Plastic and Reconstructive Surgery, University of Ottawa; Wound Healing Research Group and Alberta Diabetes Institute, Department of Surgery, and Divisions of Plastic and Reconstructive Surgery and Critical Care, University of Alberta; and the Division of Plastic and Reconstructive Surgery, McMaster University.

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http://dx.doi.org/10.1097/PRS.0000000000001782DOI Listing
December 2015

The Role of Chemokines in Fibrotic Wound Healing.

Adv Wound Care (New Rochelle) 2015 Nov;4(11):673-686

Wound Healing Research Group , Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada . ; Division of Critical Care Medicine, Department of Surgery, University of Alberta , Edmonton, Alberta, Canada .

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http://dx.doi.org/10.1089/wound.2014.0550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4620522PMC
November 2015

The natural behavior of mononuclear phagocytes in HTS formation.

Wound Repair Regen 2016 Jan-Feb;24(1):14-25. Epub 2015 Nov 20.

Division of Plastic and Reconstructive Surgery, Wound Healing Research Group, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/wrr.12378DOI Listing
January 2017

Advances in Skin Substitutes-Potential of Tissue Engineered Skin for Facilitating Anti-Fibrotic Healing.

J Funct Biomater 2015 Jul 9;6(3):547-63. Epub 2015 Jul 9.

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, 2D3.81 WMSHC, 8440-112 Street, Edmonton, AB T6G 2B7, Canada.

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http://dx.doi.org/10.3390/jfb6030547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598670PMC
July 2015

MicroRNA 181b regulates decorin production by dermal fibroblasts and may be a potential therapy for hypertrophic scar.

PLoS One 2015 2;10(4):e0123054. Epub 2015 Apr 2.

Division of Plastic Surgery, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada; Wound Healing Research Group, Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada; Division of Critical Care, Department of Medicine, University of Alberta Hospital, Edmonton, Alberta, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123054PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383602PMC
April 2016

A novel subpopulation of peripheral blood mononuclear cells presents in major burn patients.

Burns 2015 Aug 12;41(5):998-1007. Epub 2015 Feb 12.

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, 2D2.28 WMC, 8440-112 Street, Edmonton, AB, Canada T6G 2B7; Division of Critical Care Medicine, Department of Surgery, University of Alberta, 2D2.28 WMC, 8440-112 Street, Edmonton, AB, Canada T6G 2B7. Electronic address:

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http://dx.doi.org/10.1016/j.burns.2014.12.005DOI Listing
August 2015

A systematic review of post-surgical pyoderma gangrenosum: identification of risk factors and proposed management strategy.

J Plast Reconstr Aesthet Surg 2015 Mar 29;68(3):295-303. Epub 2014 Dec 29.

Division of Dermatology, Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bjps.2014.12.036DOI Listing
March 2015

The effect of keratinocytes on the biomechanical characteristics and pore microstructure of tissue engineered skin using deep dermal fibroblasts.

Biomaterials 2014 Dec 28;35(36):9591-8. Epub 2014 Aug 28.

Division of Plastic and Reconstructive Surgery, University of Alberta, 2D3.81 WMSHC, 8440-112 Street, Edmonton, Alberta T6G 2B7, Canada; Critical Care Medicine, University of Alberta, 2D3.81 WMSHC, 8440-112 Street, Edmonton, Alberta T6G 2B7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2014.07.048DOI Listing
December 2014

The therapeutic potential of a C-X-C chemokine receptor type 4 (CXCR-4) antagonist on hypertrophic scarring in vivo.

Wound Repair Regen 2014 Sep-Oct;22(5):622-30

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://doi.wiley.com/10.1111/wrr.12208
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http://dx.doi.org/10.1111/wrr.12208DOI Listing
June 2015

Biology and principles of scar management and burn reconstruction.

Surg Clin North Am 2014 Aug;94(4):793-815

Shriners Hospital for Children and Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.suc.2014.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286257PMC
August 2014

Fibrocytes participate in the development of heterotopic ossification.

J Burn Care Res 2015 May-Jun;36(3):394-404

From the *Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta, Edmonton, Canada; †Division of Critical Care Medicine; and ‡Firefighters' Burn Treatment Unit, Department of Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1097/BCR.0000000000000102DOI Listing
March 2016

Multiple Marjolin's ulcers arising from irradiated post-burn hypertrophic scars: a case report.

Burns 2014 Jun 26;40(4):e21-5. Epub 2013 Nov 26.

Department of Surgery, University of Alberta, 2D2.28 WMC, 8440-112 Street, Edmonton, Alberta T6G 2B7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.burns.2013.10.008DOI Listing
June 2014

Urodynamic improvements following oral medical therapy for partial bladder outlet obstruction in an animal model.

Neurourol Urodyn 2015 Mar 26;34(3):286-91. Epub 2013 Nov 26.

Division of Urology, Department of Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1002/nau.22528DOI Listing
March 2015

Fibrotic remodeling of tissue-engineered skin with deep dermal fibroblasts is reduced by keratinocytes.

Tissue Eng Part A 2014 Feb 9;20(3-4):716-27. Epub 2013 Nov 9.

1 Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta , Edmonton, Canada .

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http://dx.doi.org/10.1089/ten.TEA.2013.0434DOI Listing
February 2014

Novel methods for the investigation of human hypertrophic scarring and other dermal fibrosis.

Methods Mol Biol 2013 ;1037:203-31

Wound Healing Research Group, Plastic Surgery Research Laboratory, Department of Surgery, University of Alberta, Edmonton, AB, Canada.

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http://link.springer.com/10.1007/978-1-62703-505-7_11
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http://dx.doi.org/10.1007/978-1-62703-505-7_11DOI Listing
July 2014

Superficial dermal fibroblasts enhance basement membrane and epidermal barrier formation in tissue-engineered skin: implications for treatment of skin basement membrane disorders.

Tissue Eng Part A 2014 Feb 17;20(3-4):540-52. Epub 2013 Oct 17.

1 Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta , Edmonton, Canada .

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http://dx.doi.org/10.1089/ten.TEA.2013.0160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926179PMC
February 2014

Blunt carotid artery injury after minor facial trauma.

Can J Plast Surg 2012 ;20(3):194-6

Division of Plastic and Reconstructive Surgery;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433818PMC
http://dx.doi.org/10.1177/229255031202000301DOI Listing
September 2013

Characterization of heterotopic ossification in burn patients.

J Burn Care Res 2014 May-Jun;35(3):251-6

From the *Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, †Division of Critical Care Medicine, and ‡Firefighters' Burn Treatment Unit, Department of Surgery, University of Alberta, Edmonton, Canada.

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https://academic.oup.com/jbcr/article/35/3/251-256/4568711
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http://dx.doi.org/10.1097/BCR.0b013e3182957768DOI Listing
January 2015

Deep dermal fibroblast profibrotic characteristics are enhanced by bone marrow-derived mesenchymal stem cells.

Wound Repair Regen 2013 May-Jun;21(3):448-55. Epub 2013 Apr 29.

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/wrr.12046DOI Listing
December 2013

The molecular mechanism of hypertrophic scar.

J Cell Commun Signal 2013 Dec 18;7(4):239-52. Epub 2013 Mar 18.

Wound Healing Research Group, Department of Surgery, University of Alberta, WMC 2D2.28, 8440-112 Street, Edmonton AB, Canada, T6G 2B7.

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http://dx.doi.org/10.1007/s12079-013-0195-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3889252PMC
December 2013

The mouse excisional wound splinting model, including applications for stem cell transplantation.

Nat Protoc 2013 Feb 17;8(2):302-9. Epub 2013 Jan 17.

School of Life Sciences, Tsinghua University, Beijing, China.

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http://dx.doi.org/10.1038/nprot.2013.002DOI Listing
February 2013

Strategies to increase flap survival in nasal reconstruction in patients with deep panfacial burns.

J Burn Care Res 2013 Jan-Feb;34(1):e42-7

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1097/BCR.0b013e3182676c91DOI Listing
June 2013

A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar.

Wound Repair Regen 2013 Jan-Feb;21(1):77-87. Epub 2012 Nov 5.

Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1524-475X.2012.00856.xDOI Listing
July 2013

The use of laser Doppler imaging as a predictor of burn depth and hypertrophic scar postburn injury.

J Burn Care Res 2012 Nov-Dec;33(6):764-71

From the Department of Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1097/BCR.0b013e318257db36DOI Listing
May 2013

Differential expression of class I small leucine-rich proteoglycans in an animal model of partial bladder outlet obstruction.

J Urol 2012 Oct 19;188(4 Suppl):1543-8. Epub 2012 Aug 19.

Division of Urology, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1016/j.juro.2012.03.045DOI Listing
October 2012

Complications of chlorine inhalation in a pediatric chemical burn patient: a case report.

J Burn Care Res 2012 Jul-Aug;33(4):e216-21

Wound Healing Research Group, Department of Surgery, Division of Plastic Surgery,University of Alberta, Edmonton, Canada.

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https://academic.oup.com/jbcr/article/33/4/e216-e221/4588277
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http://dx.doi.org/10.1097/BCR.0b013e318254d1c8DOI Listing
December 2012

Impaired cutaneous wound healing in transforming growth factor-β inducible early gene1 knockout mice.

Wound Repair Regen 2012 Mar-Apr;20(2):166-77

Division of Plastic and Reconstructive Surgery and Critical Care, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1524-475X.2012.00773.xDOI Listing
June 2012

Carotid rupture following electrical injury: a report of two cases.

J Burn Care Res 2012 May-Jun;33(3):e160-5

Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1097/BCR.0b013e318239ca75DOI Listing
September 2012

Deep dermal fibroblasts refractory to migration and decorin-induced apoptosis contribute to hypertrophic scarring.

J Burn Care Res 2012 Sep-Oct;33(5):668-77

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1097/BCR.0b013e31824088e3DOI Listing
February 2013

Stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 in the formation of postburn hypertrophic scar (HTS).

Wound Repair Regen 2011 Sep-Oct;19(5):568-78

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1111/j.1524-475X.2011.00724.xDOI Listing
March 2012

Reduced decorin, fibromodulin, and transforming growth factor-β3 in deep dermis leads to hypertrophic scarring.

J Burn Care Res 2012 Mar-Apr;33(2):218-27

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1097/BCR.0b013e3182335980DOI Listing
July 2012

Orthostatic convulsive syncope in a burn patient.

J Burn Care Res 2012 Jan-Feb;33(1):e14-6

University of Alberta, Edmonton, Canada.

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https://academic.oup.com/jbcr/article/33/1/e14-e16/4602134
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http://dx.doi.org/10.1097/BCR.0b013e318233b60dDOI Listing
May 2012

Review of burn injuries secondary to home oxygen.

J Burn Care Res 2012 Mar-Apr;33(2):212-7

Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1097/BCR.0b013e3182331dc6DOI Listing
July 2012

Differential collagen-glycosaminoglycan matrix remodeling by superficial and deep dermal fibroblasts: potential therapeutic targets for hypertrophic scar.

Biomaterials 2011 Oct 30;32(30):7581-91. Epub 2011 Jul 30.

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta T6G 2B7, Canada.

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http://dx.doi.org/10.1016/j.biomaterials.2011.06.070DOI Listing
October 2011

Dynamic signals for hair follicle development and regeneration.

Stem Cells Dev 2012 Jan 7;21(1):7-18. Epub 2011 Sep 7.

Life Science Division, Tsinghua University Graduate School at Shenzhen, China.

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http://dx.doi.org/10.1089/scd.2011.0230DOI Listing
January 2012

Small leucine-rich proteoglycans, decorin and fibromodulin, are reduced in postburn hypertrophic scar.

Wound Repair Regen 2011 May-Jun;19(3):368-78. Epub 2011 Apr 21.

Wound Healing Research Group, Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1524-475X.2011.00677.xDOI Listing
October 2011

Human hypertrophic scar-like nude mouse model: characterization of the molecular and cellular biology of the scar process.

Wound Repair Regen 2011 Mar-Apr;19(2):274-85

Wound Healing Research Group, Department of Surgery, Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://doi.wiley.com/10.1111/j.1524-475X.2011.00672.x
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http://dx.doi.org/10.1111/j.1524-475X.2011.00672.xDOI Listing
June 2011

Toll-like receptors expressed by dermal fibroblasts contribute to hypertrophic scarring.

J Cell Physiol 2011 May;226(5):1265-73

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://doi.wiley.com/10.1002/jcp.22454
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http://dx.doi.org/10.1002/jcp.22454DOI Listing
May 2011

Bladder outlet obstruction: progression from inflammation to fibrosis.

BJU Int 2010 Dec;106(11):1686-94

Division of Paediatric Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1464-410X.2010.09445.xDOI Listing
December 2010

Infection control in the burn unit.

Burns 2011 Feb 18;37(1):5-15. Epub 2010 Jun 18.

Division of Plastic and Reconstructive Surgery and Critical Care, Department of Surgery, University of Alberta, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1016/j.burns.2009.06.198DOI Listing
February 2011

Concise review: bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration.

Stem Cells 2010 May;28(5):905-15

Life Science Division, Graduate School at Shenzhen, Tsinghua University, Beijing, People's Republic of China.

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http://dx.doi.org/10.1002/stem.420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964514PMC
May 2010

Does nanocrystalline silver have a transferable effect?

Wound Repair Regen 2010 Mar-Apr;18(2):254-65. Epub 2010 Mar 12.

Department of Chemical and Materials Engineering, University of Alberta, Edmonton, AB, Canada.

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September 2010

Anti-inflammatory activity of nanocrystalline silver-derived solutions in porcine contact dermatitis.

J Inflamm (Lond) 2010 Feb 19;7:13. Epub 2010 Feb 19.

Department of Chemical and Materials Engineering, University of Alberta, W7-002 ECERF, Edmonton, Alberta, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2841158PMC
February 2010

Scar and contracture: biological principles.

Hand Clin 2009 Nov;25(4):511-28

Division of Plastic and Reconstructive Surgery, Department of Surgery, 2D2.28 WMC, University of Alberta, 8440-112 Street, Edmonton, AB T6G 2B7, Canada.

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http://dx.doi.org/10.1016/j.hcl.2009.06.007DOI Listing
November 2009

Pathophysiology and management of the burn scar.

Clin Plast Surg 2009 Oct;36(4):661-74

Department of Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1016/j.cps.2009.05.014DOI Listing
October 2009

Analysis of allogenicity of mesenchymal stem cells in engraftment and wound healing in mice.

PLoS One 2009 Sep 22;4(9):e7119. Epub 2009 Sep 22.

College of Animal Science, South China Agricultural University, Wushan, Guangzhou, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743192PMC
September 2009

Wound healing: from embryos to adults and back again.

Lancet 2009 Apr;373(9671):1226-8

Critical Care Medicine, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1016/S0140-6736(09)60705-4DOI Listing
April 2009

Deep dermal fibroblasts contribute to hypertrophic scarring.

Lab Invest 2008 Dec 27;88(12):1278-90. Epub 2008 Oct 27.

1Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1038/labinvest.2008.101DOI Listing
December 2008

Cellular and molecular pathology of HTS: basis for treatment.

Wound Repair Regen 2007 Sep-Oct;15 Suppl 1:S6-17

Department of Surgery, University of Alberta Hospital, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1524-475X.2007.00219.xDOI Listing
January 2008

Bone marrow-derived stem cells in wound healing: a review.

Wound Repair Regen 2007 Sep-Oct;15 Suppl 1:S18-26

Wound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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January 2008

Improved scar in postburn patients following interferon-alpha2b treatment is associated with decreased angiogenesis mediated by vascular endothelial cell growth factor.

J Interferon Cytokine Res 2008 Jul;28(7):423-34

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://www.liebertpub.com/doi/10.1089/jir.2007.0104
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July 2008

Increased severity of bleomycin-induced skin fibrosis in mice with leukocyte-specific protein 1 deficiency.

J Invest Dermatol 2008 Dec 26;128(12):2767-76. Epub 2008 Jun 26.

Wound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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December 2008

Anti-inflammatory activity of nanocrystalline silver in a porcine contact dermatitis model.

Nanomedicine 2008 Sep 11;4(3):241-51. Epub 2008 Jun 11.

Department of Chemical and Materials Engineering, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1016/j.nano.2008.04.006DOI Listing
September 2008

Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing.

PLoS One 2008 Apr 2;3(4):e1886. Epub 2008 Apr 2.

Department of Surgery, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2270908PMC
April 2008

The effectiveness of pressure garment therapy for the prevention of abnormal scarring after burn injury: a meta-analysis.

J Plast Reconstr Aesthet Surg 2009 Jan 14;62(1):77-84. Epub 2008 Jan 14.

Division of Plastic and Reconstructive Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1016/j.bjps.2007.10.052DOI Listing
January 2009

Improvement in postburn hypertrophic scar after treatment with IFN-alpha2b is associated with decreased fibrocytes.

J Interferon Cytokine Res 2007 Nov;27(11):921-30

Wound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1089/jir.2007.0008DOI Listing
November 2007

Accelerated wound healing in leukocyte-specific, protein 1-deficient mouse is associated with increased infiltration of leukocytes and fibrocytes.

J Leukoc Biol 2007 Dec;82(6):1554-63

Wound Healing Research Group Division of Plastic and Reconstructive Surgery and Critical Care, Department of Surgery, University of Alberta, Edmonton, Alberta T6G 2B7, Canada.

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http://dx.doi.org/10.1189/0507306DOI Listing
December 2007

Hypertrophic scar, wound contraction and hyper-hypopigmentation.

J Burn Care Res 2007 Jul-Aug;28(4):593-7

Division of Plastic Surgery, Department of Surgery, University of Washington, Harborview Medical Center, 325 Ninth Avenue, Seattle, WA 98104, USA.

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October 2007

The basis of fibrosis and wound healing disorders following thermal injury.

Authors:
Edward E Tredget

J Trauma 2007 Jun;62(6 Suppl):S69

Firefighters' Burn Treatment Unit, University of Alberta, Edmonton, Alberta, Canada.

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June 2007

The impact of nosocomially-acquired resistant Pseudomonas aeruginosa infection in a burn unit.

J Trauma 2007 Jul;63(1):164-71

Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta Hospital, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1097/01.ta.0000240175.18189.afDOI Listing
July 2007

Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis.

Stem Cells 2007 Oct 5;25(10):2648-59. Epub 2007 Jul 5.

161 HMRC, University of Alberta, 113 Street & 87 Avenue, Edmonton, Alberta T6G 2E1, Canada.

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http://dx.doi.org/10.1634/stemcells.2007-0226DOI Listing
October 2007

Toxic shock syndrome in an adult burn patient.

Burns 2007 Dec 30;33(8):1051-3. Epub 2007 Apr 30.

Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alberta Hospital, Edmonton, Alberta, Canada T6G 2B7.

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December 2007

Fibrocytes from burn patients regulate the activities of fibroblasts.

Wound Repair Regen 2007 Jan-Feb;15(1):113-21

Wound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1111/j.1524-475X.2006.00192.xDOI Listing
June 2007

The effect of treating infected skin grafts with Acticoat on immune cells.

Burns 2007 Feb 31;33(1):52-8. Epub 2006 Oct 31.

Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alta., Canada T6G 2P5.

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http://dx.doi.org/10.1016/j.burns.2006.04.027DOI Listing
February 2007

Polarized Th2 cytokine production in patients with hypertrophic scar following thermal injury.

J Interferon Cytokine Res 2006 Mar;26(3):179-89

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery and Critical Care, University of Alberta, Edmonton, Alberta, T6G 2B7, Canada.

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http://dx.doi.org/10.1089/jir.2006.26.179DOI Listing
March 2006

Fibroblast extracellular matrix gene expression in response to keratinocyte-releasable stratifin.

J Cell Biochem 2006 May;98(2):383-93

Department of Surgery, BC Professional Firefighter's Burn and Wound Healing Research Lab, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1002/jcb.20782DOI Listing
May 2006

Local expression of indoleamine 2,3-dioxygenase protects engraftment of xenogeneic skin substitute.

J Invest Dermatol 2006 Jan;126(1):128-36

Department of Surgery, University of Alberta, Edmonton, Alberta, Canada T6G 2E1.

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January 2006

Antifibrogenic effects of liposome-encapsulated IFN-alpha2b cream on skin wounds in a fibrotic rabbit ear model.

J Interferon Cytokine Res 2005 Oct;25(10):627-31

Department of Surgery, Wound Healing Research Group, University of Alberta, Edmonton, Alberta, Canada T6G 2B7.

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http://www.liebertpub.com/doi/10.1089/jir.2005.25.627
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October 2005

Quality-of-life and outcome predictors following massive burn injury.

Plast Reconstr Surg 2005 Sep;116(3):791-7

Division of Plastic Surgery and Critical Care Medicine, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1097/01.prs.0000176257.22583.4bDOI Listing
September 2005

Stratifin-induced matrix metalloproteinase-1 in fibroblast is mediated by c-fos and p38 mitogen-activated protein kinase activation.

J Invest Dermatol 2005 Aug;125(2):230-8

Wound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, AB, Canada.

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August 2005

Fluorescent-activated cell-sorting analysis of intracellular interferon-gamma and interleukin-4 in fresh and frozen human peripheral blood T-helper cells.

Wound Repair Regen 2005 Jul-Aug;13(4):441-9

Wound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1111/j.1067-1927.2005.130412.xDOI Listing
December 2005

Identification of fibrocytes in postburn hypertrophic scar.

Wound Repair Regen 2005 Jul-Aug;13(4):398-404

Wound Healing Research Group, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

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http://doi.wiley.com/10.1111/j.1067-1927.2005.130407.x
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December 2005

Pathophysiology of chronic nonhealing wounds.

J Burn Care Rehabil 2005 Jul-Aug;26(4):306-19

Wound Healing Research Group, Division of Plastic and Reconstructive Surgery, University of Alberta, 8440-112 Street, Edmonton, Alberta, Canada T6G 2B7.

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http://dx.doi.org/10.1097/01.bcr.0000169887.04973.3aDOI Listing
December 2005

Interaction of keratinocytes and fibroblasts modulates the expression of matrix metalloproteinases-2 and -9 and their inhibitors.

Mol Cell Biochem 2005 Jan;269(1-2):209-16

Department of Pharmacology, Cardiovascular Research Group, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1007/s11010-005-3178-xDOI Listing
January 2005

Transforming growth factor-beta and its effect on reepithelialization of partial-thickness ear wounds in transgenic mice.

Wound Repair Regen 2005 Jan-Feb;13(1):61-7

Department of Surgery, Division of Plastic Surgery, Wound Healing Research Group, University of Alberta, Edmonton, Alberta, Canada.

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http://doi.wiley.com/10.1111/j.1067-1927.2005.130108.x
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July 2005

Insulin suppresses collagenase stimulatory effect of stratifin in dermal fibroblasts.

Mol Cell Biochem 2004 Nov;266(1-2):167-74

Department of Surgery, Wound Healing Research Group, University of Alberta, Edmonton, Canada.

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http://link.springer.com/content/pdf/10.1023/B:MCBI.00000491
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http://dx.doi.org/10.1023/b:mcbi.0000049156.82563.2dDOI Listing
November 2004