Eduardo Vilar

Eduardo Vilar

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Eduardo Vilar

Eduardo Vilar

Publications by authors named "Eduardo Vilar"

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62Publications

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Mismatch Repair-Proficient Colorectal Cancer: Finding the Right TiME to Respond.

Clin Cancer Res 2019 Sep 1;25(17):5185-5187. Epub 2019 Jul 1.

Department of GI Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-1447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726523PMC
September 2019

Immune Activation in Mismatch Repair Deficient Carcinogenesis: More Than Just Mutational Rate.

Clin Cancer Res 2019 Aug 5. Epub 2019 Aug 5.

Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center

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http://dx.doi.org/10.1158/1078-0432.CCR-18-0856DOI Listing
August 2019

Outcomes of disease-specific next-generation sequencing gene panel testing in adolescents and young adults with colorectal cancer.

Cancer Genet 2019 Jun 26;235-236:77-83. Epub 2019 Apr 26.

Department of Clinical Cancer Prevention, UT MD Anderson Cancer Center, Unit 1360, P.O. Box 301439, Houston, TX 77230-1439, USA; Gastrointestinal Medical Oncology, UT MD Anderson Cancer Center, Unit 426, 1515 Holcombe Blvd., Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2019.04.064DOI Listing
June 2019

Genetic predisposition to colorectal cancer: syndromes, genes, classification of genetic variants and implications for precision medicine.

J Pathol 2019 Apr 20;247(5):574-588. Epub 2019 Feb 20.

Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1002/path.5229DOI Listing
April 2019

Targeted Therapy for Cancer-Associated Fibroblasts: Are We There Yet?

J Natl Cancer Inst 2018 01;110(1)

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1093/jnci/djx131DOI Listing
January 2018

Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer.

Genome Res 2017 08 25;27(8):1287-1299. Epub 2017 May 25.

Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1101/gr.209973.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538546PMC
August 2017

Frameshift mutational target gene analysis identifies similarities and differences in constitutional mismatch repair-deficiency and Lynch syndrome.

Mol Carcinog 2017 07 30;56(7):1753-1764. Epub 2017 Mar 30.

Molecular Oncology and Immunotherapy, Rostock University Medical Center, Rostock, Germany.

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http://dx.doi.org/10.1002/mc.22632DOI Listing
July 2017

SPDEF Induces Quiescence of Colorectal Cancer Cells by Changing the Transcriptional Targets of β-catenin.

Gastroenterology 2017 07 5;153(1):205-218.e8. Epub 2017 Apr 5.

Integrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, Houston, Texas; Department of Medicine and Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas; Division of Medicine, Section of Gastroenterology & Hepatology, Baylor College of Medicine, Houston, Texas. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.03.048DOI Listing
July 2017

Beyond COX-1: the effects of aspirin on platelet biology and potential mechanisms of chemoprevention.

Cancer Metastasis Rev 2017 06;36(2):289-303

Department of Cancer Systems Imaging, Division of Diagnostic Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1007/s10555-017-9675-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557878PMC
June 2017

Universal Genetic Testing for Younger Patients With Colorectal Cancer.

JAMA Oncol 2017 04;3(4):448-449

Department of Internal Medicine, University of Michigan, Ann Arbor.

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http://dx.doi.org/10.1001/jamaoncol.2016.5193DOI Listing
April 2017

Oncogenic targets Mmp7, S100a9, Nppb and Aldh1a3 from transcriptome profiling of FAP and Pirc adenomas are downregulated in response to tumor suppression by Clotam.

Int J Cancer 2017 Jan 18;140(2):460-468. Epub 2016 Oct 18.

Center for Epigenetics & Disease Prevention, Texas A&M University Institute of Biosciences & Technology, Houston, TX.

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http://dx.doi.org/10.1002/ijc.30458DOI Listing
January 2017

Rapid and powerful detection of subtle allelic imbalance from exome sequencing data with hapLOHseq.

Bioinformatics 2016 10 10;32(19):3015-7. Epub 2016 Jun 10.

The Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, TX, USA Department of Epidemiology.

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http://dx.doi.org/10.1093/bioinformatics/btw340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039922PMC
October 2016

DNA Mismatch Repair Deficiency in Rectal Cancer: Benchmarking Its Impact on Prognosis, Neoadjuvant Response Prediction, and Clinical Cancer Genetics.

J Clin Oncol 2016 09 18;34(25):3039-46. Epub 2016 Jul 18.

Nicole de Rosa, Miguel A. Rodriguez-Bigas, George J. Chang, Jula Veerapong, Ester Borras, Sunil Krishnan, Brian Bednarski, Craig A. Messick, John M. Skibber, Barry W. Feig, Patrick M. Lynch, Eduardo Vilar, and Y. Nancy You, University of Texas MD Anderson Cancer Center, Houston, TX; Nicole de Rosa, University of Nebraska Medical Center, Omaha, NE; and Jula Veerapong, St Louis University, St Louis, MO.

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http://dx.doi.org/10.1200/JCO.2016.66.6826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012714PMC
September 2016

Leveraging premalignant biology for immune-based cancer prevention.

Proc Natl Acad Sci U S A 2016 09 16;113(39):10750-8. Epub 2016 Sep 16.

Department of Medicine, Moores Cancer Center, University of California San Diego, La Jolla, CA 92093;

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047191PMC
http://dx.doi.org/10.1073/pnas.1608077113DOI Listing
September 2016

Aspirin for Cancer Prevention: One Step Closer.

JAMA Oncol 2016 Jun;2(6):770-1

Division of Cancer Prevention and Population Sciences, Department of Clinical Cancer Prevention, University of Texas MD Anderson Cancer Center, Houston.

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http://dx.doi.org/10.1001/jamaoncol.2015.6395DOI Listing
June 2016

Genomic Landscape of Colorectal Mucosa and Adenomas.

Cancer Prev Res (Phila) 2016 06 24;9(6):417-27. Epub 2016 May 24.

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas. Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas. Clinical Cancer Genetics Program, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1940-6207.CAPR-16-0081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941624PMC
June 2016

Reply to L.B. Saltz.

J Clin Oncol 2016 05 29;34(13):1560-1. Epub 2016 Feb 29.

The University of Texas MD Anderson Cancer Center, Houston, TX

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http://dx.doi.org/10.1200/JCO.2015.66.2049DOI Listing
May 2016

Multistage vector delivery of sulindac and silymarin for prevention of colon cancer.

Colloids Surf B Biointerfaces 2015 Dec 9;136:694-703. Epub 2015 Oct 9.

Department of Nanomedicine, Houston Methodist Research Institute, Houston, TX 77030, USA; Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.colsurfb.2015.10.005DOI Listing
December 2015

Cancer in silico drug discovery: a systems biology tool for identifying candidate drugs to target specific molecular tumor subtypes.

Mol Cancer Ther 2014 Dec 27;13(12):3230-40. Epub 2014 Oct 27.

The Graduate School of Biomedical Sciences, The University of Texas Health Science Center at Houston, Houston, Texas. Department of Epidemiology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-14
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http://dx.doi.org/10.1158/1535-7163.MCT-14-0260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341901PMC
December 2014

Urinary PGE-M in colorectal cancer: predicting more than risk?

Cancer Prev Res (Phila) 2014 Oct 28;7(10):969-72. Epub 2014 Jul 28.

Division of Cancer Prevention and Population Sciences, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1940-6207.CAPR-14-0215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185234PMC
October 2014

Establishing a diagnostic road map for MUTYH-associated polyposis.

Clin Cancer Res 2014 Mar 31;20(5):1061-3. Epub 2014 Jan 31.

Authors' Affiliations: Departments of Clinical Cancer Prevention, Pathology, and Gastroenterology, Hepatology and Nutrition, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-3295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996649PMC
March 2014

Patient-reported disease knowledge and educational needs in Lynch syndrome: findings of an interactive multidisciplinary patient conference.

Hered Cancer Clin Pract 2014 Feb 5;12(1). Epub 2014 Feb 5.

Department of Surgical Oncology, The University of Texas M, D, Anderson Cancer Center, Houston, Texas, USA.

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http://dx.doi.org/10.1186/1897-4287-12-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922108PMC
February 2014

Mismatch repair status and clinical outcome in endometrial cancer: a systematic review and meta-analysis.

Crit Rev Oncol Hematol 2013 Oct 4;88(1):154-67. Epub 2013 Apr 4.

Division of Medical Oncology, Centro Integral Oncologico Clara Campal, Hospital Universitario HM Sanchinarro, Madrid, Spain; Division of Medical Oncology and Hematology, Princess Margaret Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2013.03.002DOI Listing
October 2013

Molecular dissection of microsatellite instable colorectal cancer.

Cancer Discov 2013 May 1;3(5):502-11. Epub 2013 Mar 1.

Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651752PMC
May 2013

Classifying MMR variants: time for revised nomenclature in Lynch syndrome.

Clin Cancer Res 2013 May 26;19(9):2280-2. Epub 2013 Mar 26.

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77230, USA.

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http://clincancerres.aacrjournals.org/content/early/2013/04/
Web Search
http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
Publisher Site
http://dx.doi.org/10.1158/1078-0432.CCR-13-0392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854938PMC
May 2013

Trends in digestive cancer mortality, Cuba 1987-2008.

Eur J Public Health 2013 Feb 7;23(1):164-70. Epub 2012 Feb 7.

Department of Biostatistics, National Institute of Gastroenterology, Havana, Cuba.

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http://dx.doi.org/10.1093/eurpub/ckr210DOI Listing
February 2013

Cancer: Pinprick diagnostics.

Nature 2012 Jun 27;486(7404):482-3. Epub 2012 Jun 27.

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http://dx.doi.org/10.1038/486482aDOI Listing
June 2012

Micromanaging the classification of colon cancer: the role of the microRNAome.

Clin Cancer Res 2011 Dec 21;17(23):7207-9. Epub 2011 Oct 21.

Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2440DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422018PMC
December 2011

Molecular predictors of response to chemotherapy in colorectal cancer.

Cancer J 2011 Mar-Apr;17(2):114-26

Medical Oncology Department, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1097/PPO.0b013e318212f844DOI Listing
July 2011

Pushing the envelope in the mTOR pathway: the second generation of inhibitors.

Mol Cancer Ther 2011 Mar 7;10(3):395-403. Epub 2011 Jan 7.

Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan Medical Center, C369 Med Inn Bldg, 1500 E. Medical Center Dr., Ann Arbor, MI, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-10
Publisher Site
http://dx.doi.org/10.1158/1535-7163.MCT-10-0905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413411PMC
March 2011

Microsatellite instability in colorectal cancer-the stable evidence.

Nat Rev Clin Oncol 2010 Mar 9;7(3):153-62. Epub 2010 Feb 9.

Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://www.nature.com/articles/nrclinonc.2009.237
Publisher Site
http://dx.doi.org/10.1038/nrclinonc.2009.237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427139PMC
March 2010

Chemotherapy and role of the proliferation marker Ki-67 in digestive neuroendocrine tumors.

Endocr Relat Cancer 2007 Jun;14(2):221-32

Department of Medical Oncology, Vall d'Hebron University Hospital, Barcelona 08035, Spain.

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http://dx.doi.org/10.1677/ERC-06-0074DOI Listing
June 2007

[New challenges for molecular oncology in ovarian carcinoma].

Med Clin (Barc) 2007 Jan;128(1):15-7

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http://dx.doi.org/10.1016/s0025-7753(07)72466-1DOI Listing
January 2007