Eduardo Tolosa

Eduardo Tolosa

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Eduardo Tolosa

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Emergencies and critical issues in Parkinson's disease.

Pract Neurol 2019 Aug 19. Epub 2019 Aug 19.

Neurology Department, Hospital Clinic de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1136/practneurol-2018-002075DOI Listing
August 2019

Progression of two Progressive Supranuclear Palsy phenotypes with comparable initial disability.

Parkinsonism Relat Disord 2019 Jul 9. Epub 2019 Jul 9.

Clinical and Translational Research Institute, UC San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2019.07.010DOI Listing
July 2019

-synuclein RT-QuIC in cerebrospinal fluid of LRRK2-linked Parkinson's disease.

Ann Clin Transl Neurol 2019 Jun 9;6(6):1024-1032. Epub 2019 May 9.

The National CJD Research & Surveillance Unit Centre for Clinical Brain Sciences University of Edinburgh Edinburgh EH4 2XU United Kingdom.

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http://dx.doi.org/10.1002/acn3.772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562027PMC
June 2019

Co-morbid demyelinating lesions and atypical clinical features in a patient with Parkinson's disease.

Parkinsonism Relat Disord 2019 May 2;62:242-245. Epub 2019 Feb 2.

Neurological Tissue Bank of the Biobanc-Hospital Clinic-IDIBAPS, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain; Institute of Neurology, Medical University of Vienna, Allgemeines Krankenhaus der Stadt Wien, Waehringer Guertel 18-20, 1090, Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2019.01.015DOI Listing
May 2019

Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease.

Stem Cell Reports 2019 Feb 10;12(2):213-229. Epub 2019 Jan 10.

Department of Pathology and Experimental Therapeutics, Bellvitge University Hospital-IDIBELL, Hospitalet de Llobregat, Barcelona 08908, Spain; Institute of Biomedicine of the University of Barcelona (IBUB), Barcelona 08028, Spain; Department of Molecular and Translational Medicine, University of Brescia, Brescia 25121, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.12.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372974PMC
February 2019

Axial motor clues to identify atypical parkinsonism: A multicentre European cohort study.

Parkinsonism Relat Disord 2018 11 8;56:33-40. Epub 2018 Jun 8.

Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Parkinson Centre Nijmegen (ParC) Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.06.015DOI Listing
November 2018

Myoclonus-Dominant Corticobasal Degeneration.

Mov Disord Clin Pract 2018 Nov-Dec;5(6):649-652. Epub 2018 Nov 6.

Parkinson and Movement Disorders Unit, Neurology department, Hospital Clinic of Barcelona Institut Clínic de Neurociències, Hospital Clínic Barcelona Spain.

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http://dx.doi.org/10.1002/mdc3.12670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277364PMC
November 2018

Opicapone for the treatment of Parkinson's disease: A review of a new licensed medicine.

Mov Disord 2018 10 27;33(10):1528-1539. Epub 2018 Sep 27.

Departments of Clinical Pharmacology and Neurosciences, Clinical Investigation Center CIC 1436, NS-Park/FCRIN network and NeuroToul COEN Center, INSERM, CHU de Toulouse, Université de Toulouse 3, Toulouse, France.

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http://dx.doi.org/10.1002/mds.27475DOI Listing
October 2018

Two-hundred Years Later: Is Parkinson's Disease a Single Defined Entity?

Rev Invest Clin 2017 Nov-Dec;69(6):308-313

Neurological Tissue Bank, Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid and Universidad de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.24875/RIC.17002291DOI Listing
July 2018

Extrastriatal monoaminergic dysfunction and enhanced microglial activation in idiopathic rapid eye movement sleep behaviour disorder.

Neurobiol Dis 2018 07 6;115:9-16. Epub 2018 Mar 6.

Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Denmark; Division of Neuroscience, Newcastle University, England, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.02.017DOI Listing
July 2018

An observational study of rotigotine transdermal patch and other currently prescribed therapies in patients with Parkinson's disease.

J Neural Transm (Vienna) 2018 06 26;125(6):953-963. Epub 2018 Feb 26.

Department of Neurology, University Hospital Marburg, Marburg, Germany.

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http://dx.doi.org/10.1007/s00702-018-1860-xDOI Listing
June 2018

Glucocerebrosidase gene variants are accumulated in idiopathic REM sleep behavior disorder.

Parkinsonism Relat Disord 2018 05 21;50:94-98. Epub 2018 Feb 21.

Department of Pathology, Hospital Universitari and Health Sciences Research Institute Germans Trias i Pujol, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.02.034DOI Listing
May 2018

A Novel p.Glu298Lys Mutation in the ACMSD Gene in Sporadic Parkinson's Disease.

J Parkinsons Dis 2017 ;7(3):459-463

Department of Neurology, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY, USA.

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http://dx.doi.org/10.3233/JPD-171146DOI Listing
April 2018

α-synuclein (SNCA) but not dynamin 3 (DNM3) influences age at onset of leucine-rich repeat kinase 2 (LRRK2) Parkinson's disease in Spain.

Mov Disord 2018 04 23;33(4):637-641. Epub 2018 Feb 23.

Laboratory of Parkinson Disease and Other Neurodegenerative Movement Disorders, Clinical and Experimental Research, Department of Neurology, Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/mds.27295DOI Listing
April 2018

Lack of pathogenic potential of peripheral α-synuclein aggregates from Parkinson's disease patients.

Acta Neuropathol Commun 2018 02 8;6(1). Epub 2018 Feb 8.

Neurodegenerative Diseases Research Group, Vall d'Hebron Research Institute-Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), 08035, Barcelona, Spain.

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http://dx.doi.org/10.1186/s40478-018-0509-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806361PMC
February 2018

Expanding the phenotype toward spastic paraparesis: A mutation in the M2 domain.

Neurol Genet 2018 Feb 24;4(1):e214. Epub 2018 Jan 24.

Department of Neurology (A.J.E.W., R.Z., M.A.J.T.), and Department of Genetics (F.V., A.H.v.d.H., T.J.d.K.), University Medical Center Groningen, University of Groningen; Department of Pediatrics (J.M.), Deventer Hospital, The Netherlands; and Parkinson's Disease and Movement Disorders Unit (E.T.), Hospital Clinic of Barcelona, Institut Clínic de Neurociències, Barcelona, Spain.

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http://dx.doi.org/10.1212/NXG.0000000000000214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5820596PMC
February 2018

l-Dopa/carbidopa intestinal gel and subthalamic nucleus stimulation: Effects on cognition and behavior.

Brain Behav 2017 11 20;7(11):e00848. Epub 2017 Oct 20.

Parkinson and Movement Disorders Unit Neurology Service Institut Clínic de Neurociències Hospital Clínic Barcelona Spain.

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http://dx.doi.org/10.1002/brb3.848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698866PMC
November 2017

Assessment of neuroinflammation in patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study.

Lancet Neurol 2017 10 3;16(10):789-796. Epub 2017 Jul 3.

Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark; Institute of Neuroscience, Newcastle University, Newcastle, England. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30173-4DOI Listing
October 2017

Opicapone for the management of end-of-dose motor fluctuations in patients with Parkinson's disease treated with L-DOPA.

Expert Rev Neurother 2017 Jul 5;17(7):649-659. Epub 2017 Jun 5.

g Department of Neurology , Innsbruck Medical University , Innsbruck , Austria.

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http://dx.doi.org/10.1080/14737175.2017.1336086DOI Listing
July 2017

Aggregation of α-Synuclein in the Gonadal Tissue of 2 Patients With Parkinson Disease.

JAMA Neurol 2017 05;74(5):606-607

Parkinson's Disease and Movement Disorders Unit, Institut Clínic de Neurociències, Hospital Clinic of Barcelona, Barcelona, Spain2Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.

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http://archneur.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaneurol.2016.6155DOI Listing
May 2017

association with REM sleep behavior disorder.

Neurol Genet 2017 Feb 13;3(1):e131. Epub 2017 Jan 13.

Laboratory of Neurodegenerative Disorders (R.F.-S., M.F., E.T., M.E.), Multidisciplinary Sleep Unit (A.I., C.G., M.S., J.S.), Movement Disorders Unit (E.T.), Department of Neurology, Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED) (R.F.-S., A.I., C.G., M.S., M.F., E.T., J.S., M.E.), Madrid; and Movement Disorders Unit (P.P.), Department of Neurology, University Hospital Mutua de Terrassa, Barcelona, Spain.

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http://ng.neurology.org/lookup/doi/10.1212/NXG.0000000000000
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http://dx.doi.org/10.1212/NXG.0000000000000131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5238706PMC
February 2017

Consensus on the Definition of Advanced Parkinson's Disease: A Neurologists-Based Delphi Study (CEPA Study).

Parkinsons Dis 2017 23;2017:4047392. Epub 2017 Jan 23.

Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain; Neurology Service, Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1155/2017/4047392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292396PMC
January 2017

Total α-synuclein levels in human blood cells, CSF, and saliva determined by a lipid-ELISA.

Anal Bioanal Chem 2016 Nov 13;408(27):7669-7677. Epub 2016 Sep 13.

Biochemistry and Molecular Biology, IMRIC, The Hebrew University-Hadassah Medical School, Ein Kerem, 91120, Jerusalem, Israel.

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http://dx.doi.org/10.1007/s00216-016-9863-7DOI Listing
November 2016

White matter hyperintensities, cerebrospinal amyloid-β and dementia in Parkinson's disease.

J Neurol Sci 2016 Aug 11;367:284-90. Epub 2016 Jun 11.

Parkinson disease & Movement Disorders Unit, Neurology Service, Institut Clínic de Neurociències (ICN), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Centro de Investigación en Red de Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, University of Barcelona, Barcelona, Catalonia, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2016.06.009DOI Listing
August 2016

Assessment of α-synuclein in submandibular glands of patients with idiopathic rapid-eye-movement sleep behaviour disorder: a case-control study.

Lancet Neurol 2016 06 30;15(7):708-718. Epub 2016 Mar 30.

Neurological Tissue Bank, Biobanc-Hospital Clinic, Instituto de Investigaciones Biomédicas August Pi i Sunyer, Barcelona, Spain.

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http://dx.doi.org/10.1016/S1474-4422(16)00080-6DOI Listing
June 2016

Cerebrospinal fluid biomarkers and clinical features in leucine-rich repeat kinase 2 (LRRK2) mutation carriers.

Mov Disord 2016 06 4;31(6):906-14. Epub 2016 Apr 4.

Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut de Neurociències Hospital Clínic, University of Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/mds.26591DOI Listing
June 2016

Challenges of modifying disease progression in prediagnostic Parkinson's disease.

Lancet Neurol 2016 05 16;15(6):637-48. Epub 2016 Mar 16.

Parkinson's Disease Research, August Pi i Sunyer Biomedical Research Institute, University of Barcelona, Barcelona, Spain; Parkinson Disease and Movement Disorder Unit, Neurology Service, Hospital Clínic de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Universidad de Barcelona, Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(16)00060-0DOI Listing
May 2016

Idiopathic rapid eye movement sleep behaviour disorder: diagnosis, management, and the need for neuroprotective interventions.

Lancet Neurol 2016 Apr;15(4):405-19

Neurology Service, Multidisciplinary Sleep Unit, Hospital Clinic de Barcelona, IDIBAPS, CIBERNED, Barcelona, Spain.

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http://dx.doi.org/10.1016/S1474-4422(16)00057-0DOI Listing
April 2016

Absence of LRRK2 mutations in a cohort of patients with idiopathic REM sleep behavior disorder.

Neurology 2016 Mar 8;86(11):1072-3. Epub 2016 Jan 8.

From the Laboratory of Neurodegenerative Disorders (R.F.-S., M.F., E.T., M.E.), Multidisciplinary Sleep Unit (A.I., C.G., M.S., J.S.), and Movement Disorders Unit (E.T.), Department of Neurology, Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona; and Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (R.F.-S., A.I., C.G., M.S., M.F., E.T., J.S., M.E.), Madrid, Spain.

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http://dx.doi.org/10.1212/WNL.0000000000002304DOI Listing
March 2016

Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.

EMBO Mol Med 2015 Dec;7(12):1529-46

Laboratory of Neurodegenerative Disorders, Department of Neurology, Hospital Clínic of Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) University of Barcelona (UB), Barcelona, Spain Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain Cell Therapy Program, Faculty of Medicine, University of Barcelona (UB), Barcelona, Spain Movement Disorders Unit, Department of Neurology, Hospital Clínic of Barcelona Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) University of Barcelona (UB), Barcelona, Spain.

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http://dx.doi.org/10.15252/emmm.201505439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693505PMC
December 2015

Enteric nervous system α-synuclein immunoreactivity in idiopathic REM sleep behavior disorder.

Neurology 2015 Nov 16;85(20):1761-8. Epub 2015 Oct 16.

From the Departments of Neurology (F.S.S., N.S., K.S., B.H., B.F., G.K.W., W.P.) and Gastroenterology (W.V.), Medical University of Innsbruck, Austria; Neurological Tissue Bank of the Biobanc-Hospital Clinic de Barcelona (E.G.), IDIBAPS; the Departments of Neurology (J.N.-O., D.V., F.V., C.P.-S., C.G., A.I., E.T.), Pathology (I.A., M.C.), and Gastroenterology (A.G.), Hospital Clinic de Barcelona, Spain; and the Institute of Pathology (F.O.), Academic Teaching Hospital, Feldkirch, Austria.

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http://dx.doi.org/10.1212/WNL.0000000000002126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653104PMC
November 2015

Clinical and imaging markers in premotor LRRK2 G2019S mutation carriers.

Parkinsonism Relat Disord 2015 Oct 12;21(10):1170-6. Epub 2015 Aug 12.

Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut de Neurociències Hospital Clínic, University of Barcelona, Catalonia, Spain; Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2015.08.007DOI Listing
October 2015

Levodopa-Induced Nocturnal Stereotypies with Logorrhea in a Patient with Parkinson's Disease.

Mov Disord Clin Pract 2015 Sep 28;2(3):301-303. Epub 2015 Mar 28.

Movement Disorder Unit Neurology Service Hospital Clínic Barcelona Barcelona Spain.

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http://dx.doi.org/10.1002/mdc3.12150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353415PMC
September 2015

Long-term response to continuous duodenal infusion of levodopa/carbidopa gel in patients with advanced Parkinson disease: The Barcelona registry.

Parkinsonism Relat Disord 2015 Aug 19;21(8):871-6. Epub 2015 May 19.

Parkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic, University of Barcelona, Spain; Instituto de Investigaciones Biomédicas August Pi I Sunyer - IDIBAPS, Barcelona, Spain; CIBERNED Carlos III Health Institute, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2015.05.014DOI Listing
August 2015

Peripheral synuclein tissue markers: a step closer to Parkinson's disease diagnosis.

Brain 2015 Aug;138(Pt 8):2120-2

Neurology Service, Hospital Clínic, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), IDIBAPS, Universitat de Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1093/brain/awv164DOI Listing
August 2015

Nonmotor symptoms in LRRK2 G2019S associated Parkinson's disease.

PLoS One 2014 17;9(10):e108982. Epub 2014 Oct 17.

Parkinson's Disease and Movement Disorders Unit, Neurology Service, Institut de Neurociències Hospital Clínic, University of Barcelona, Barcelona, Spain; Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108982PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201457PMC
July 2015

Brainstem raphe and substantia nigra echogenicity in idiopathic REM sleep behavior disorder with comorbid depression.

J Neurol 2015 Jul 1;262(7):1665-72. Epub 2015 May 1.

Neurology Service, Hospital Clinic de Barcelona, IDIBAPS, CIBERNED, C/Villarroel 170, 08036, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00415-015-7745-0DOI Listing
July 2015

Cystatin C is differentially involved in multiple system atrophy phenotypes.

Neuropathol Appl Neurobiol 2015 Jun;41(4):507-19

Servicio de Anatomía Patológica, Instituto de Investigación en Ciencias de la Salud Germans Trias i Pujol, Hospital Universitario Germans Trias i Pujol, Barcelona, Spain.

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http://dx.doi.org/10.1111/nan.12134DOI Listing
June 2015

Prevalence and timeline of nonmotor symptoms in idiopathic rapid eye movement sleep behavior disorder.

J Neurol 2015 Jun 1;262(6):1568-78. Epub 2015 May 1.

Neurology Service, Hospital Clinic de Barcelona, IDIBAPS, CIBERNED, C/Villarroel 170, 08036, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00415-015-7742-3DOI Listing
June 2015

Disclosure of research results in genetic studies of Parkinson's disease caused by LRRK2 mutations.

Mov Disord 2015 Jun 7;30(7):904-8. Epub 2015 May 7.

Department of Neurology, Mount Sinai Beth Israel Medical Center, New York, NY, USA.

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http://dx.doi.org/10.1002/mds.26250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478096PMC
June 2015

MicroRNA association with synucleinopathy conversion in rapid eye movement behavior disorder.

Ann Neurol 2015 May 13;77(5):895-901. Epub 2015 Mar 13.

Laboratory of Neurodegenerative Disorders, Department of Neurology, Hospital Clínic of Barcelona, August Pi i Sunyer Biomedical Research Institute (IDIBAPS), University of Barcelona, Barcelona; Center for Biomedical Research in Neurodegenerative Diseases, Madrid.

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http://dx.doi.org/10.1002/ana.24384DOI Listing
May 2015

Resting-state frontostriatal functional connectivity in Parkinson's disease-related apathy.

Mov Disord 2015 Apr 20;30(5):671-9. Epub 2015 Jan 20.

Departament de Psiquiatria i Psicobiologia Clínica, Universitat de Barcelona. Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/mds.26137DOI Listing
April 2015

The onset of nonmotor symptoms in Parkinson's disease (the ONSET PD study).

Mov Disord 2015 Feb 1;30(2):229-37. Epub 2014 Dec 1.

Neurology Service, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Catalonia, Spain.

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http://dx.doi.org/10.1002/mds.26077DOI Listing
February 2015

Olfactory dysfunction predicts early transition to a Lewy body disease in idiopathic RBD.

Neurology 2015 Feb 21;84(7):654-8. Epub 2015 Jan 21.

From the Department of Neurology (P.M., B.H., B.F., C.M., T.M., V.G., F.B., C.S., W.P., K.S.), Medical University Innsbruck; Department of Medical Statistics, Informatics and Health Economics (G.G.), Medical University Innsbruck, Austria; Neurology Service (A.I., J.S., E.T., M.S.), Hospital Clinic, Barcelona; Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED) (A.I., J.S., E.T., M.S.); and IDIBAPS (A.I., J.S., E.T., M.S.), Barcelona, Spain.

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http://dx.doi.org/10.1212/WNL.0000000000001265DOI Listing
February 2015

Cognitive impairment and resting-state network connectivity in Parkinson's disease.

Hum Brain Mapp 2015 Jan 28;36(1):199-212. Epub 2014 Aug 28.

Departament de Psiquiatria i Psicobiologia Clínica, Universitat de Barcelona, Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/hbm.22622DOI Listing
January 2015

Four pioneers of L-dopa treatment: Arvid Carlsson, Oleh Hornykiewicz, George Cotzias, and Melvin Yahr.

Mov Disord 2015 Jan 8;30(1):19-36. Epub 2014 Dec 8.

The National Hospital, Queen Square and University College London, London, UK.

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http://dx.doi.org/10.1002/mds.26120DOI Listing
January 2015

The phenotypic spectrum of progressive supranuclear palsy: a retrospective multicenter study of 100 definite cases.

Mov Disord 2014 Dec 5;29(14):1758-66. Epub 2014 Nov 5.

Department of Neurology, Technische Universität München, Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany; Department of Neurology, Philipps Universität, Marburg, Germany.

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http://www.neurokopfzentrum.med.tum.de/pdf/respondek2014.pdf
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http://doi.wiley.com/10.1002/mds.26054
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http://dx.doi.org/10.1002/mds.26054DOI Listing
December 2014

Cortical thinning associated with mild cognitive impairment in Parkinson's disease.

Mov Disord 2014 Oct 7;29(12):1495-503. Epub 2014 Aug 7.

Institute of Biomedical Research August Pi i Sunyer (IDIBAPS), Catalonia, Spain; Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/mds.25982DOI Listing
October 2014

Functional brain networks and cognitive deficits in Parkinson's disease.

Hum Brain Mapp 2014 Sep 17;35(9):4620-34. Epub 2014 Mar 17.

Departament de Psiquiatria i Psicobiologia Clinica, Universitat de Barcelona, Spain.

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http://dx.doi.org/10.1002/hbm.22499DOI Listing
September 2014

Multiple organ involvement by alpha-synuclein pathology in Lewy body disorders.

Mov Disord 2014 Jul 2;29(8):1010-8. Epub 2014 Jan 2.

Neurological Tissue Bank of the Biobanc-Hospital Clinic-Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1002/mds.25776DOI Listing
July 2014

Analysis of Parkinson's disease brain-derived DNA for alpha-synuclein coding somatic mutations.

Mov Disord 2014 Jul 21;29(8):1060-4. Epub 2014 Apr 21.

Department of Clinical Neuroscience, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.25883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190821PMC
July 2014

A distinct variant of mixed dysarthria reflects parkinsonism and dystonia due to ephedrone abuse.

J Neural Transm (Vienna) 2014 Jun 21;121(6):655-64. Epub 2014 Jan 21.

Department of Circuit Theory, Faculty of Electrical Engineering, Czech Technical University in Prague, Prague, Czech Republic.

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June 2014

Symptomatic efficacy of rasagiline monotherapy in early Parkinson's disease: post-hoc analyses from the ADAGIO trial.

Parkinsonism Relat Disord 2014 Jun 5;20(6):640-3. Epub 2014 Mar 5.

Neurology Service, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, IDIBAPS, Universitat de Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.parkreldis.2014.02.024DOI Listing
June 2014

Efficacy of levodopa/carbidopa/entacapone versus levodopa/carbidopa in patients with early Parkinson's disease experiencing mild wearing-off: a randomised, double-blind trial.

J Neural Transm (Vienna) 2014 Apr 20;121(4):357-66. Epub 2013 Nov 20.

Neurology Service, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain,

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April 2014

A phase 2 trial of the GSK-3 inhibitor tideglusib in progressive supranuclear palsy.

Mov Disord 2014 Apr 14;29(4):470-8. Epub 2014 Feb 14.

Neurology Service, Hospital Clinic de Barcelona, Universidad de Barcelona, Institut d'Investigacions Biomédiques August Pi i Sunyer (IDIBAPS), Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Spain.

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http://dx.doi.org/10.1002/mds.25824DOI Listing
April 2014

Regional vulnerability of hippocampal subfields and memory deficits in Parkinson's disease.

Hippocampus 2013 Aug 30;23(8):720-8. Epub 2013 Apr 30.

Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1002/hipo.22131DOI Listing
August 2013

Parkinson disease: New guidelines for diagnosis of Parkinson disease.

Nat Rev Neurol 2013 Apr 26;9(4):190-1. Epub 2013 Mar 26.

Servicio de Neurologia, Hospital Clinic de Barcelona (IDIBAPS; CIBERNED), Villarroel 170, 08036 Barcelona, Spain.

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http://dx.doi.org/10.1038/nrneurol.2013.47DOI Listing
April 2013

Alpha-synuclein aggregates in epicardial fat tissue in living subjects without parkinsonism.

Parkinsonism Relat Disord 2013 Jan 1;19(1):27-31; discussion 27. Epub 2012 Aug 1.

Parkinson's Disease and Movement Disorders Unit, Neurology Service, Hospital Clínic, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1016/j.parkreldis.2012.07.005DOI Listing
January 2013

Levodopa in the treatment of Parkinson's disease: current status and new developments.

J Parkinsons Dis 2013 Jan;3(3):255-69

Universitat Autònoma de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.3233/JPD-130186DOI Listing
January 2013

Progression of cortical thinning in early Parkinson's disease.

Mov Disord 2012 Dec 2;27(14):1746-53. Epub 2012 Nov 2.

Centro de Investigación en Red de Enfermedades Neurodegenerativas, Hospital Clínic de Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1002/mds.25240DOI Listing
December 2012

Assessment of cortical degeneration in patients with Parkinson's disease by voxel-based morphometry, cortical folding, and cortical thickness.

Hum Brain Mapp 2012 Nov 6;33(11):2521-34. Epub 2011 Sep 6.

Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Spain.

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http://dx.doi.org/10.1002/hbm.21378DOI Listing
November 2012

Grey matter volume correlates of cerebrospinal markers of Alzheimer-pathology in Parkinson's disease and related dementia.

Parkinsonism Relat Disord 2012 Sep 15;18(8):941-7. Epub 2012 May 15.

Parkinson's Disease & Movement Disorders Unit, Neurology Service, Institut Clínic de Neurociències/IDIBAPS, Centro de Investigación en Red de Enfermedades Neurodegenerativas, Hospital Clínic, Barcelona, Catalonia, Spain.

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September 2012

Donepezil in Parkinson's disease dementia: a randomized, double-blind efficacy and safety study.

Mov Disord 2012 Sep 22;27(10):1230-8. Epub 2012 Aug 22.

Université Pierre et Marie Curie-Paris 6, Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière (CRICM), UMR-S975, France.

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http://dx.doi.org/10.1002/mds.25098DOI Listing
September 2012

Perampanel in Parkinson disease fluctuations: a double-blind randomized trial with placebo and entacapone.

Clin Neuropharmacol 2012 Jan-Feb;35(1):15-20

Institut National de la Santé et de la Recherche Médicale Clinical Investigation Center, Toulouse University Hospital and University of Toulouse, France.

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http://dx.doi.org/10.1097/WNF.0b013e318241520bDOI Listing
May 2012

Premotor signs and symptoms of multiple system atrophy.

Lancet Neurol 2012 Apr 19;11(4):361-8. Epub 2012 Mar 19.

Clinic of Neurology, School of Medicine, University of Belgrade, Serbia.

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http://dx.doi.org/10.1016/S1474-4422(12)70022-4DOI Listing
April 2012

Impulse control disorders in Parkinson's disease.

Parkinsonism Relat Disord 2012 Jan;18 Suppl 1:S80-4

Institut Clínic de Neurodències, Hospital Clínic de Barcelona, Department of Medicine, Universitat de Barcelona, IDIBAPS, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Barcelona, Catalonia, Spain.

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http://dx.doi.org/10.1016/S1353-8020(11)70026-8DOI Listing
January 2012

Brain structural MRI correlates of cognitive dysfunctions in Parkinson's disease.

J Neurol Sci 2011 Nov 23;310(1-2):70-4. Epub 2011 Aug 23.

Centro de Investigación en Red de Enfermedades Neurodegenerativas (CIBERNED), Hospital Clínic de Barcelona, Spain.

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http://dx.doi.org/10.1016/j.jns.2011.07.054DOI Listing
November 2011

Idiopathic Parkinson's syndrome. Preface.

J Neurol Sci 2011 Nov 3;310(1-2). Epub 2011 Sep 3.

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http://dx.doi.org/10.1016/j.jns.2011.08.011DOI Listing
November 2011