Eduardo M Sotomayor

Eduardo M Sotomayor

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Eduardo M Sotomayor

Eduardo M Sotomayor

Publications by authors named "Eduardo M Sotomayor"

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High Red Cell Distribution Width is an Adverse Predictive and Prognostic Factor in Patients With Diffuse Large B-Cell Lymphoma Treated With Chemoimmunotherapy.

Clin Lymphoma Myeloma Leuk 2019 Sep 15;19(9):e551-e557. Epub 2019 Jun 15.

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.clml.2019.06.005DOI Listing
September 2019

Recent advances and future directions in mantle cell lymphoma research: report of the 2018 mantle cell lymphoma consortium workshop.

Leuk Lymphoma 2019 Aug 30;60(8):1853-1865. Epub 2019 Jan 30.

f GW Cancer Center, George Washington University , Washington , DC , USA.

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http://dx.doi.org/10.1080/10428194.2019.1571205DOI Listing
August 2019

BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models.

Cancer Cell 2019 May;35(5):752-766.e9

Chemical Biology and Molecular Medicine Program, Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA; Department of Laboratory Medicine and Hematopathology, Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.04.005DOI Listing
May 2019

The neutrophil-lymphocyte ratio is prognostic in patients with early stage aggressive peripheral T cell lymphoma.

Br J Haematol 2019 Feb 26;184(4):650-653. Epub 2018 Feb 26.

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/bjh.15141DOI Listing
February 2019

Loss of HDAC11 ameliorates clinical symptoms in a multiple sclerosis mouse model.

Life Sci Alliance 2018 Oct 24;1(5):e201800039. Epub 2018 Sep 24.

George Washington University Cancer Center, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

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http://www.life-science-alliance.org/lookup/doi/10.26508/lsa
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http://dx.doi.org/10.26508/lsa.201800039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238389PMC
October 2018

EBV-positive diffuse large B-cell lymphoma, not otherwise specified: 2018 update on diagnosis, risk-stratification and management.

Am J Hematol 2018 07;93(7):953-962

Department of Hematology and Oncology, George Washington Cancer Center, George Washington University, Washington, DC.

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http://dx.doi.org/10.1002/ajh.25112DOI Listing
July 2018

The impact of the neutrophil:lymphocyte ratio in response and survival of patients with de novo diffuse large B-cell lymphoma.

Leuk Res 2018 04 19;67:82-85. Epub 2018 Feb 19.

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.leukres.2018.02.011DOI Listing
April 2018

Response and survival benefit with chemoimmunotherapy in Epstein-Barr virus-positive diffuse large B-cell lymphoma.

Hematol Oncol 2018 Feb 22;36(1):93-97. Epub 2017 Jun 22.

Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1002/hon.2449DOI Listing
February 2018

Mantle Cell Lymphoma: Contemporary Diagnostic and Treatment Perspectives in the Age of Personalized Medicine.

Hematol Oncol Stem Cell Ther 2017 Sep 6;10(3):99-115. Epub 2017 Apr 6.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

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http://dx.doi.org/10.1016/j.hemonc.2017.02.003DOI Listing
September 2017

Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function.

Sci Rep 2017 08 17;7(1):8626. Epub 2017 Aug 17.

Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Diseases, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1038/s41598-017-09211-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561267PMC
August 2017

Recent advances and future directions in mantle cell lymphoma research: report of the 2016 mantle cell lymphoma consortium workshop.

Leuk Lymphoma 2017 07 31;58(7):1561-1569. Epub 2017 Jan 31.

e Department of Medicine, George Washington University , Washington DC , USA.

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http://dx.doi.org/10.1080/10428194.2017.1283036DOI Listing
July 2017

The neutrophil-to-lymphocyte ratio is an independent prognostic factor in patients with peripheral T-cell lymphoma, unspecified.

Leuk Lymphoma 2016 19;57(1):58-62. Epub 2015 Jun 19.

d Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Harvard Medical School Boston , MA , USA.

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http://dx.doi.org/10.3109/10428194.2015.1045897DOI Listing
October 2016

Advances and issues in mantle cell lymphoma research: report of the 2014 Mantle Cell Lymphoma Consortium Workshop.

Leuk Lymphoma 2015 25;56(9):2505-11. Epub 2015 May 25.

e H. Lee Moffitt Cancer Center and Research Institute , Tampa , FL , USA.

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http://dx.doi.org/10.3109/10428194.2015.1045903DOI Listing
August 2016

Lymphomatoid Granulomatosis: A Single Institution Experience and Review of the Literature.

Clin Lymphoma Myeloma Leuk 2016 08;16 Suppl:S170-4

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research, Tampa, FL.

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http://dx.doi.org/10.1016/j.clml.2016.02.024DOI Listing
August 2016

EBV-positive diffuse large B-cell lymphoma of the elderly: 2016 update on diagnosis, risk-stratification, and management.

Am J Hematol 2016 May;91(5):529-37

Department of Hematology and Oncology, George Washington Cancer Center, George Washington University, Washington, DC.

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http://dx.doi.org/10.1002/ajh.24370DOI Listing
May 2016

HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade.

Cancer Immunol Res 2015 Dec 21;3(12):1375-85. Epub 2015 Aug 21.

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.

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http://dx.doi.org/10.1158/2326-6066.CIR-15-0077-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674300PMC
December 2015

Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function.

Mol Immunol 2015 Feb 23;63(2):579-85. Epub 2014 Aug 23.

Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States; Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2014.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4252813PMC
February 2015

Clinical characteristics and prognostic factors of bone lymphomas: focus on the clinical significance of multifocal bone involvement by primary bone large B-cell lymphomas.

BMC Cancer 2014 Dec 2;14:900. Epub 2014 Dec 2.

Department of Hematopathology and Laboratory Medicine, H, Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.

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http://dx.doi.org/10.1186/1471-2407-14-900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265495PMC
December 2014

Quantitative flow cytometric identification of aberrant T cell clusters in erythrodermic cutaneous T cell lymphoma. Implications for staging and prognosis.

J Clin Pathol 2014 May 6;67(5):431-6. Epub 2013 Dec 6.

Department of Hematopathology and Labororatory Medicine, H. Lee Moffitt Cancer Center, , Tampa, Florida, USA.

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http://dx.doi.org/10.1136/jclinpath-2013-201748DOI Listing
May 2014

Epigenetic regulation of a brain-specific glycosyltransferase N-acetylglucosaminyltransferase-IX (GnT-IX) by specific chromatin modifiers.

J Biol Chem 2014 Apr 10;289(16):11253-61. Epub 2014 Mar 10.

From the Disease Glycomics Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, Global Research Cluster, RIKEN, Wako 351-0198, Japan and.

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http://dx.doi.org/10.1074/jbc.M114.554311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036263PMC
April 2014

Selective histone deacetylase 6 inhibitors bearing substituted urea linkers inhibit melanoma cell growth.

J Med Chem 2012 Nov 23;55(22):9891-9. Epub 2012 Oct 23.

Drug Discovery Program, Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1021/jm301098eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562128PMC
November 2012

Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity.

Cancer Res 2012 Sep 22;72(17):4440-8. Epub 2012 Jun 22.

Departments of Malignant Hematology, Drug Discovery, and Hematopathology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-3619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990429PMC
September 2012

Mantle cell lymphoma: a clinically heterogeneous disease in need of tailored approaches.

Cancer Control 2012 Jul;19(3):227-35

Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL 33612, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015063PMC
http://dx.doi.org/10.1177/107327481201900307DOI Listing
July 2012

Modulation of antigen-presenting cells by HDAC inhibitors: implications in autoimmunity and cancer.

Immunol Cell Biol 2012 Jan 22;90(1):55-65. Epub 2011 Nov 22.

Department of Immunology, H Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1038/icb.2011.96DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990411PMC
January 2012

Epigenetic repolarization of T lymphocytes from chronic lymphocytic leukemia patients using 5-aza-2'-deoxycytidine.

Leuk Res 2011 Sep 5;35(9):1193-9. Epub 2011 Mar 5.

Department of Experimental Therapeutics at H. Lee Moffitt Cancer Center, Tampa, FL 33612-9416, USA.

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http://dx.doi.org/10.1016/j.leukres.2011.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607255PMC
September 2011

EBV-positive diffuse large B-cell lymphoma of the elderly: a case series from Peru.

Am J Hematol 2011 Aug;86(8):663-7

Department of Oncology and Radiotherapy, Edgardo Rebagliati Martins Hospital, Lima, Peru.

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http://dx.doi.org/10.1002/ajh.22078DOI Listing
August 2011

Outcome of diffuse large B-Cell lymphoma in the United States has improved over time but racial disparities remain: review of SEER data.

Clin Lymphoma Myeloma Leuk 2011 Jun 20;11(3):257-60. Epub 2011 Apr 20.

Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1016/j.clml.2011.03.012DOI Listing
June 2011

Restoring the functional immunogenicity of chronic lymphocytic leukemia using epigenetic modifiers.

Leuk Res 2011 Mar 22;35(3):394-404. Epub 2010 Sep 22.

Department of Malignant Hematology, Immunology, and Experimental Therapeutics, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

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http://dx.doi.org/10.1016/j.leukres.2010.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458853PMC
March 2011

Follicular dendritic cell-dependent drug resistance of non-Hodgkin lymphoma involves cell adhesion-mediated Bim down-regulation through induction of microRNA-181a.

Blood 2010 Dec 14;116(24):5228-36. Epub 2010 Sep 14.

Department of Malignant Hematology, Molecular Oncology and Experimental Therapeutics Program, H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, FL, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-03-27
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http://dx.doi.org/10.1182/blood-2010-03-275925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012540PMC
December 2010

"Skulls and bones" new member: Th17.

Blood 2010 Nov;116(18):3380-2

Moffitt Cancer Center & Research Institute.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2010-08-30
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http://dx.doi.org/10.1182/blood-2010-08-300574DOI Listing
November 2010

Enhanced CD8 T cell cross-presentation by macrophages with targeted disruption of STAT3.

Immunol Lett 2010 Jul 25;131(2):126-30. Epub 2010 Mar 25.

Department of Immunology and Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, United States.

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http://dx.doi.org/10.1016/j.imlet.2010.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2906450PMC
July 2010

Circumventing immune tolerance through epigenetic modification.

Curr Pharm Des 2010 Jan;16(3):268-76

Department of Immunology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

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http://dx.doi.org/10.2174/138161210790170120DOI Listing
January 2010

TLR5 ligation by flagellin converts tolerogenic dendritic cells into activating antigen-presenting cells that preferentially induce T-helper 1 responses.

Immunol Lett 2009 Aug 23;125(2):114-8. Epub 2009 Jun 23.

Division of Immunology and Division of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL 33612, United States.

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http://dx.doi.org/10.1016/j.imlet.2009.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758552PMC
August 2009

Monoclonal antibodies for B-cell lymphomas: rituximab and beyond.

Hematology Am Soc Hematol Educ Program 2007 :233-42

Lee Moffitt Cancer Center and Research Inst., 12902 Magnolia Drive, MRC 3 East, Room 3056D, Tampa, FL 33612-9497, USA.

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http://dx.doi.org/10.1182/asheducation-2007.1.233DOI Listing
July 2009

Identification of a novel negative role of flagellin in regulating IL-10 production.

Eur J Immunol 2007 Nov;37(11):3164-75

Division of Immunology, Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center & Research Institute, University of South Florida, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1002/eji.200737306DOI Listing
November 2007

Immunosuppressive strategies that are mediated by tumor cells.

Annu Rev Immunol 2007 ;25:267-96

Division of Immunogenetics, Hospital de Clínicas José de San Martín, University of Buenos Aires, Buenos Aires, Argentina.

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http://dx.doi.org/10.1146/annurev.immunol.25.022106.141609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895922PMC
June 2007

Cellular and molecular mechanisms of tumor-induced T-cell tolerance.

Curr Cancer Drug Targets 2007 Feb;7(1):41-53

Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612-9497, USA.

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February 2007

In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by B-cell lymphomas leading to antitumor immunity.

Blood 2006 Apr 8;107(7):2871-8. Epub 2005 Dec 8.

Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, MRC 4 East, Rm 4072-H, 12902 Magnolia Dr, Tampa, FL 33612-9497, USA.

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http://dx.doi.org/10.1182/blood-2005-07-3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895389PMC
April 2006

Immune tolerance in breast cancer.

Breast Dis 2004 ;20:93-103

Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center & Research Institute at the University of South Florida, Tampa, FL 33612-9497, USA.

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April 2005

Imatinib mesylate (STI-571) enhances antigen-presenting cell function and overcomes tumor-induced CD4+ T-cell tolerance.

Blood 2005 Feb 28;105(3):1135-43. Epub 2004 Sep 28.

Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center & Research Institute at the University of South Florida, Tampa, FL, USA.

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http://dx.doi.org/10.1182/blood-2004-01-0027DOI Listing
February 2005

Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens.

Cancer Res 2003 Dec;63(24):9007-15

Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, Florida 33612, USA.

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December 2003

A critical role for Stat3 signaling in immune tolerance.

Immunity 2003 Sep;19(3):425-36

Department of Interdisciplinary Oncology, University of South Florida, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1016/s1074-7613(03)00232-2DOI Listing
September 2003

Cancer vaccines for hematologic malignancies.

Cancer Control 2002 Mar-Apr;9(2):138-51

Department of Oncology at the Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1177/107327480200900206DOI Listing
June 2002