Edmund V Capparelli

Edmund V Capparelli

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Edmund V Capparelli

Publications by authors named "Edmund V Capparelli"

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Darunavir Pharmacokinetics With an Increased Dose During Pregnancy.

J Acquir Immune Defic Syndr 2020 Apr;83(4):373-380

Department of Clinical Pharmacy and Pediatrics, University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA.

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http://dx.doi.org/10.1097/QAI.0000000000002261DOI Listing
April 2020

Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir.

J Clin Pharmacol 2020 Feb 6;60(2):240-255. Epub 2019 Sep 6.

Pediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel (UKBB), Basel, Switzerland.

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http://dx.doi.org/10.1002/jcph.1515DOI Listing
February 2020

Development and preclinical pharmacology of a novel dCK inhibitor, DI-87.

Biochem Pharmacol 2020 Feb 6;172:113742. Epub 2019 Dec 6.

Division of Hematology-Oncology, University of California San Diego, La Jolla, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.113742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981055PMC
February 2020

Population pharmacokinetic analysis of high-dose methotrexate in pediatric and adult oncology patients.

Cancer Chemother Pharmacol 2019 Dec 4;84(6):1339-1348. Epub 2019 Oct 4.

Division of Host-Microbe Systems and Therapeutics, University of California San Diego, 9500 Gilman Drive MC 0657, La Jolla, CA, 92093, USA.

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http://link.springer.com/10.1007/s00280-019-03966-4
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http://dx.doi.org/10.1007/s00280-019-03966-4DOI Listing
December 2019

Population pharmacokinetics of siltuximab: impact of disease state.

Cancer Chemother Pharmacol 2019 Nov 3;84(5):993-1001. Epub 2019 Sep 3.

Division of Host-Microbe Systems and Therapeutics, University of California San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1007/s00280-019-03939-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800650PMC
November 2019

Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum.

J Clin Pharmacol 2019 03 25;59(3):386-393. Epub 2018 Oct 25.

Division of Maternal Fetal Medicine, Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/jcph.1331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368469PMC
March 2019

Sertraline Pharmacokinetics in HIV-Infected and Uninfected Children, Adolescents, and Young Adults.

Front Pediatr 2019 6;7:16. Epub 2019 Feb 6.

Department of Pediatrics-Rady Children's Hospital San Diego, University of California, San Diego, San Diego, CA, United States.

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http://dx.doi.org/10.3389/fped.2019.00016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372542PMC
February 2019

Infliximab Pharmacokinetics are Influenced by Intravenous Immunoglobulin Administration in Patients with Kawasaki Disease.

Clin Pharmacokinet 2018 12;57(12):1593-1601

Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/s40262-018-0653-6DOI Listing
December 2018

Population Pharmacokinetics of Lopinavir/Ritonavir: Changes Across Formulations and Human Development From Infancy Through Adulthood.

J Clin Pharmacol 2018 12 25;58(12):1604-1617. Epub 2018 Sep 25.

Skaggs School of Pharmacy and Pharmaceutical Science, University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1002/jcph.1293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604805PMC
December 2018

Population Pharmacokinetics and Exploratory Exposure-Response Relationships of Diazepam in Children Treated for Status Epilepticus.

CPT Pharmacometrics Syst Pharmacol 2018 11 28;7(11):718-727. Epub 2018 Sep 28.

Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://doi.wiley.com/10.1002/psp4.12349
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http://dx.doi.org/10.1002/psp4.12349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263663PMC
November 2018

Vincristine-associated Neuropathy With Antifungal Usage: A Kaiser Northern California Experience.

J Pediatr Hematol Oncol 2018 07;40(5):e273-e277

Division of Host-Microbe Systems and Therapeutics, University of California San Diego, San Diego.

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http://dx.doi.org/10.1097/MPH.0000000000001220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019195PMC
July 2018

Persistent cytarabine and daunorubicin exposure after administration of novel liposomal formulation CPX-351: population pharmacokinetic assessment.

Cancer Chemother Pharmacol 2018 01 22;81(1):171-178. Epub 2017 Nov 22.

Division of Hematology-Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s00280-017-3484-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756117PMC
January 2018

External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models.

Antimicrob Agents Chemother 2017 12 22;61(12). Epub 2017 Nov 22.

Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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http://dx.doi.org/10.1128/AAC.01352-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700313PMC
December 2017

Pharmacokinetics of single-dose ceftaroline fosamil in children with cystic fibrosis.

Pediatr Pulmonol 2017 Nov 14;52(11):1424-1434. Epub 2017 Sep 14.

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, California.

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http://dx.doi.org/10.1002/ppul.23827DOI Listing
November 2017

Population Pharmacokinetics and Exploratory Pharmacodynamics of Lorazepam in Pediatric Status Epilepticus.

Clin Pharmacokinet 2017 08;56(8):941-951

Department of Pediatrics and Skaggs School of Pharmacy, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0831, USA.

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http://dx.doi.org/10.1007/s40262-016-0486-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466505PMC
August 2017

Assessment of Nevirapine Prophylactic and Therapeutic Dosing Regimens for Neonates.

J Acquir Immune Defic Syndr 2017 08;75(5):554-560

*PHPT/IRD 174, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; †Department of Immunology and Infectious Diseases, Harvard T.H Chan School of Public Health, Boston, MA; ‡Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom; §Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; ‖Institut d'Etudes Démographiques, Paris, France; ¶Institut de Recherche pour le Développement (IRD) UMI 174-PHPT, Marseille, France; #Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; **Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA; ††Department of Pediatric, Health Promotion Center Region 10, Chiang Mai, Thailand; ‡‡Department of Pediatric, Banglamung Hospital, Chonburi, Thailand; §§Department of Pediatric, Nopparat Rajathanee Hospital, Bangkok, Thailand; ‖‖Department of Pediatric, Hat Yai Hospital, Hat Yai, Thailand; ¶¶Department of Pediatric, Samutprakarn Hospital, Samut Prakan, Thailand; ##Manchester Pharmacy School, The University of Manchester, Manchester, United Kingdom; and ***EAU7323 Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1097/QAI.0000000000001447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508655PMC
August 2017

Utility of Spot Urine Specimens to Assess Tubular Secretion.

Am J Kidney Dis 2017 May 8;69(5):709-711. Epub 2017 Mar 8.

University of California San Diego, San Diego, California. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2016.12.016DOI Listing
May 2017

CYP2B6 genotype-directed dosing is required for optimal efavirenz exposure in children 3-36 months with HIV infection.

AIDS 2017 05;31(8):1129-1136

aCentre for Infectious Disease Research in Zambia, Lusaka, Zambia bUniversity of Alabama at Birmingham, Birmingham, Alabama cUniversity of California San Diego, La Jolla dRady Children's Hospital, San Diego, California eHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA fUniversity of Zimbabwe, Harare, Zimbabwe gNational Institutes of Allergy and Infectious Diseases hEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland iFrontier Science and Technology Research Foundation, Amherst jNew York University's School of Medicine, New York, New York kUNC Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina lSocial and Scientific Systems Inc, Silver Springs, Maryland, USA mBARC-SA and Lancet Laboratories, Johannesburg, South Africa nNorthwestern University's Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623109PMC
May 2017

Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent.

Antimicrob Agents Chemother 2017 01 27;61(1). Epub 2016 Dec 27.

Departments of Pathology and Medicine, University of California, San Diego, School of Medicine, La Jolla, California, USA

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http://dx.doi.org/10.1128/AAC.01947-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192119PMC
January 2017

Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates.

J Pediatr 2016 Nov 10;178:125-129.e1. Epub 2016 Aug 10.

Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Department of Pediatrics, Duke University School of Medicine, Durham, NC.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085855PMC
http://dx.doi.org/10.1016/j.jpeds.2016.07.011DOI Listing
November 2016

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption.

N Engl J Med 2016 11 9;375(21):2037-2050. Epub 2016 Nov 9.

From the University of Pennsylvania (K.J.B., D.B.S., B.S., G.H.L., E.F.K., M.B., J.A.H., P.T.) and Children's Hospital of Philadelphia (N.B.T.) - both in Philadelphia; the Laboratory of Immunoregulation (M.C.S., J.S.J., M.E.P., J.B., E.W.R., K.E.C., S.M., A.S.F., T.-W.C.), Biostatistics Research Branch (M.A.P.), Vaccine Research Center (P.J.M., S.J.O., A.R.S., N.A.D.-R., R.T.B., J.E.L., R.M.L., B.S.G., R.A.K., J.R.M.), and Division of AIDS (R.L.T.), National Institute of Allergy and Infectious Diseases and National Institutes of Health (NIH), and the Critical Care Medicine Department, Clinical Center, NIH (C.A.S., R.W.K.), Bethesda, the AIDS Clinical Trials Group, Silver Spring (K.O.), and Columbus Technologies and Services, Greenbelt (R.L.T.) - all in Maryland; Harvard T.H. Chan School of Public Health, Boston (L.J.H.); the University of Alabama at Birmingham, Birmingham (E.T.O., M.M.); Frontier Science and Technology Research Foundation, Amherst, NY (B.J.); and the University of California, San Diego, La Jolla (E.V.C.).

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http://dx.doi.org/10.1056/NEJMoa1608243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292134PMC
November 2016

Association of concurrent acid-suppression therapy with survival outcomes and adverse event incidence in oncology patients receiving erlotinib.

Cancer Chemother Pharmacol 2016 Aug 2;78(2):427-32. Epub 2016 Jul 2.

Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Moores Cancer Center, UC San Diego Health System, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/s00280-016-3087-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967016PMC
August 2016

Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women.

J Acquir Immune Defic Syndr 2016 07;72(3):289-96

*Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA; †Skaggs School of Pharmacy and Pharmaceutical Sciences, Pediatrics Department-Rady Children's Hospital, University of California, San Diego, CA; ‡Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA; §Department of Biostatistics, Harvard School of Public Health, Boston, MA; ‖Department of Medicine, Children's Hospital Boston, Boston, MA; ¶Irmandade da Santa Casa de Misericordia de Porto Alegre, HIV/AIDS Research Department, Porto Alegre, Brazil; #Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; **FHI 360, IMPAACT Operations Office, Durham, NC; ††Program for HIV Prevention and Treatment, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; ‡‡Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, DHHS, Bethesda, MD; §§National Institute of Allergy and Infectious Diseases, Bethesda, MD; and ‖‖Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911231PMC
July 2016

A randomized controlled trial of gabapentin for chronic low back pain with and without a radiating component.

Pain 2016 07;157(7):1499-507

aVA San Diego Healthcare System, San Diego, CA, USA bDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA cScottsdale Healthcare Research Institute, Scottsdale, AZ, USA dDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, USA eComputational and Applied Statistics Laboratory, University of California, San Diego, La Jolla, CA, USA Departments of fMathematics, gAnesthesiology, and hOrthopaedic Surgery, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1097/j.pain.0000000000000554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001843PMC
July 2016

Population Pharmacokinetic Assessment and Pharmacodynamic Implications of Pediatric Cefepime Dosing for Susceptible-Dose-Dependent Organisms.

Antimicrob Agents Chemother 2016 Apr 25;60(4):2150-6. Epub 2016 Mar 25.

Center for Research in Pediatric and Developmental Pharmacology, University of California, San Diego, La Jolla, and Rady Children's Hospital, San Diego, California, USA

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http://dx.doi.org/10.1128/AAC.02592-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808231PMC
April 2016

Lopinavir/ritonavir plus lamivudine and abacavir or zidovudine dose ratios for paediatric fixed-dose combinations.

Antivir Ther 2015 3;20(2):225-33. Epub 2014 Oct 3.

EA 7323, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.3851/IMP2876DOI Listing
January 2016

Pharmacokinetics of Once Versus Twice Daily Darunavir in Pregnant HIV-Infected Women.

J Acquir Immune Defic Syndr 2015 Sep;70(1):33-41

*Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Southern California School of Medicine, Los Angeles, CA; †Department of Biostatistics, Statistical and Data Analysis Center, Harvard School of Public Health, Boston, MA; ‡Department of Medicine, Children's Hospital Boston, Boston, MA; §HIV/AIDS Research Department, Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil; ‖Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; ¶Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; #Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD; **National Institute of Allergy and Infectious Diseases, Bethesda, MD; and ††Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579345PMC
September 2015

Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study.

Clin Ther 2015 Jun 29;37(6):1340-51. Epub 2015 May 29.

University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences and School of Medicine, La Jolla, California; Rady Children's Hospital of San Diego, San Diego, California.

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http://dx.doi.org/10.1016/j.clinthera.2015.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475435PMC
June 2015

Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing.

Cancer Chemother Pharmacol 2015 Mar 4;75(3):495-503. Epub 2015 Jan 4.

University of California San Diego, 9500 Gilman Drive, MC 0657, La Jolla, CA, 92093-0657, USA.

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http://dx.doi.org/10.1007/s00280-014-2667-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344382PMC
March 2015

Adverse Event Detection and Labeling in Pediatric Drug Development: Antiretroviral Drugs.

Ther Innov Regul Sci 2015 Mar;49(2):302-309

4 Office of Clinical Pharmacology, Office of Translational Sciences, US Food and Drug Administration, Silver Spring, MD, USA.

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http://dx.doi.org/10.1177/2168479014565471DOI Listing
March 2015

Optimizing pediatric esmolol dosing using computerized practitioner order entry.

J Pediatr Pharmacol Ther 2014 Oct-Dec;19(4):302-9

University of California, San Diego, School of Medicine, San Diego, California ; University of California, San Diego, Skaggs School of Pharmacy, San Diego, California.

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http://dx.doi.org/10.5863/1551-6776-19.4.302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341416PMC
March 2015

Raltegravir pharmacokinetics during pregnancy.

J Acquir Immune Defic Syndr 2014 Dec;67(4):375-81

*Office of the Global AIDS Coordinator, U.S. Department of State, Washington, DC; †Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, CA; ‡Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA; §Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA; ‖Program for HIV Prevention and Treatment (IRD URI 174), Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; ¶Department of Clinical Pharmacy, Drug Research Unit, University of California, San Francisco, San Francisco, CA; #HIV/AIDS Research Department, Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil; **Boston Children's Hospital, Harvard Medical School, Boston, MA; ††Social and Scientific Systems, Inc, Silver Spring, MD; ‡‡Maternal, Adolescent, and Pediatric Research Branch, National Institute of Allergy and Infectious Diseases, Bethesda, MD; and §§Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213295PMC
December 2014

Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections.

Pediatr Infect Dis J 2014 Oct;33(10):e270-2

From the *Duke Clinical Research Institute; †Department of Pediatrics, Duke University, Durham; ‡Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC; §Department of Pediatric Pharmacology, University of California, San Diego, CA; and ¶Department of Neurosurgery, Duke University, Durham, NC.

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http://dx.doi.org/10.1097/INF.0000000000000385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209191PMC
October 2014

Variable and suboptimal nevirapine levels in infants given single-dose nevirapine at birth without maternal prophylaxis.

AIDS 2014 Oct;28(16):2491-3

aSeattle Children's Research Institute bUniversity of Washington, Seattle, Washington cUniversity of California San Diego, San Diego, California dHealth Alliance International, Seattle, Washington, USA eHealth Alliance International, Beira, Mozambique fUniversity of Wisconsin-Madison, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332529PMC
October 2014

Vancomycin monitoring in children using bayesian estimation.

Ther Drug Monit 2014 Aug;36(4):510-8

*Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla; †Miller Children's Hospital, Long Beach; and ‡Rady Children's Hospital, San Diego, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101060PMC
http://dx.doi.org/10.1097/FTD.0000000000000039DOI Listing
August 2014

Determining population and developmental pharmacokinetics of metronidazole using plasma and dried blood spot samples from premature infants.

Pediatr Infect Dis J 2013 Sep;32(9):956-61

From the *Department of Pediatrics, Duke University; †Duke Clinical Research Institute, Durham, NC; ‡Wichita Medical Research and Education Foundation, Wichita, KS; §Division of Infectious Diseases, CHOC-Children's Hospital of Orange County, Orange, CA; ¶Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Vanderbilt University Medical Center, Nashville, TN; ‖EMMES Corporation, Rockville, MD; **Department of Pediatrics, University of Missouri-Kansas City School of Medicine and the Division of Pediatric Pharmacology and Therapeutic Innovation, The Children's Mercy Hospital, Kansas City, MO; ††Department of Pediatric Pharmacology, University of California, San Diego, CA; and ‡‡Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.

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https://insights.ovid.com/crossref?an=00006454-201309000-000
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http://dx.doi.org/10.1097/INF.0b013e3182947cf8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769518PMC
September 2013

Determination of efavirenz in human dried blood spots by reversed-phase high-performance liquid chromatography with UV detection.

Ther Drug Monit 2013 Apr;35(2):203-8

Skagg's School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA 92093-0831, USA.

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http://dx.doi.org/10.1097/FTD.0b013e31827fb72bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848783PMC
April 2013

Developmental pharmacokinetic changes of Lamivudine in infants and children.

J Clin Pharmacol 2012 Dec 16;52(12):1824-32. Epub 2011 Dec 16.

UC San Diego Pediatric Research Center, 7910 Frost St, #360, San Diego, CA 92123, USA.

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http://dx.doi.org/10.1177/0091270011426563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369109PMC
December 2012

Pharmacokinetic considerations of perinatal antiretroviral therapy.

Curr Drug Metab 2012 Jul;13(6):744-59

Division of Infectious Disease, Children's National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

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http://dx.doi.org/10.2174/138920012800840365DOI Listing
July 2012

High dose of darunavir in treatment-experienced HIV-infected adolescent results in virologic suppression and improved CD4 cell count.

Ther Drug Monit 2012 Jun;34(3):237-41

Division of Infectious Diseases, Department of Pediatrics, Children's National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.

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http://dx.doi.org/10.1097/FTD.0b013e3182511efeDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354040PMC
June 2012

Omeprazole limited sampling strategies to predict area under the concentration-time curve ratios: implications for cytochrome P450 2C19 and 3A phenotyping.

Eur J Clin Pharmacol 2012 Apr 19;68(4):407-13. Epub 2011 Oct 19.

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego (UCSD), 9500 Gilman Drive, MC 0714, La Jolla, CA 92093-0714, USA.

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http://link.springer.com/content/pdf/10.1007/s00228-011-1136
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http://link.springer.com/10.1007/s00228-011-1136-y
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http://dx.doi.org/10.1007/s00228-011-1136-yDOI Listing
April 2012

Pharmacokinetics of intravenous lorazepam in pediatric patients with and without status epilepticus.

J Pediatr 2012 Apr 1;160(4):667-672.e2. Epub 2011 Nov 1.

Division of Emergency Medicine, Children's National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.

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http://dx.doi.org/10.1016/j.jpeds.2011.09.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274567PMC
April 2012

Pharmacokinetics of lopinavir/ritonavir crushed versus whole tablets in children.

J Acquir Immune Defic Syndr 2011 Dec;58(4):385-91

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093-0719, USA.

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http://dx.doi.org/10.1097/QAI.0b013e318232b057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205189PMC
December 2011

Innovative clinical trial design for pediatric therapeutics.

Expert Rev Clin Pharmacol 2011 Sep;4(5):643-52

School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1586/ecp.11.43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3184526PMC
September 2011

Efavirenz concentrations in CSF exceed IC50 for wild-type HIV.

J Antimicrob Chemother 2011 Feb 23;66(2):354-7. Epub 2010 Nov 23.

University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA, USA.

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http://dx.doi.org/10.1093/jac/dkq434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019085PMC
February 2011

Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease.

J Pediatr Gastroenterol Nutr 2011 Feb;52(2):198-202

Department of Pediatrics, University of California, San Diego, USA.

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http://dx.doi.org/10.1097/MPG.0b013e3181f9b3a0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059772PMC
February 2011

Lopinavir tablet pharmacokinetics with an increased dose during pregnancy.

J Acquir Immune Defic Syndr 2010 Aug;54(4):381-8

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, San Diego, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265163PMC
http://dx.doi.org/10.1097/qai.0b013e3181d6c9edDOI Listing
August 2010

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.

N Engl J Med 2010 Mar;362(9):790-9

Comprehensive Epilepsy Center, Division of Neurology, Cincinnati Children's Hospital, 3333 Burnet Ave., MLC 2015, Cincinnati, OH 45229, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa0902014
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http://dx.doi.org/10.1056/NEJMoa0902014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924476PMC
March 2010

Rapid weight gain in children soon after diagnosis of type 1 diabetes: is there room for concern?

Pediatr Diabetes 2009 Aug 20;10(5):310-5. Epub 2008 Nov 20.

Division of Pediatric Endocrinology, Department of Pediatrics, Rady Children's Hospital - San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1111/j.1399-5448.2008.00475.xDOI Listing
August 2009

Low atazanavir concentrations in cerebrospinal fluid.

AIDS 2009 Jan;23(1):83-7

Skaggs School of Pharmacy andPharmaceutical Sciences, School of Medicine, Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, MC 0719, La Jolla, CA 92093-0719, USA.

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http://dx.doi.org/10.1097/QAD.0b013e328317a702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642983PMC
January 2009

Infliximab treatment of intravenous immunoglobulin-resistant Kawasaki disease.

J Pediatr 2008 Dec 30;153(6):833-8. Epub 2008 Jul 30.

Department of Pediatrics, University of California San Diego School of Medicine and Rady Children's Hospital San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1016/j.jpeds.2008.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856847PMC
December 2008

Meropenem pharmacokinetics, pharmacodynamics, and Monte Carlo simulation in the neonate.

Pediatr Infect Dis J 2008 Sep;27(9):794-9

Division of Infectious diseases, Children's Hospital and Health Center, San Diego, CA 92123, USA.

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http://dx.doi.org/10.1097/INF.0b013e318170f8d2DOI Listing
September 2008

Implications of gender and pregnancy for antiretroviral drug dosing.

Curr Opin HIV AIDS 2008 May;3(3):277-82

University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, California, USA.

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http://dx.doi.org/10.1097/COH.0b013e3282f39f7eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804899PMC
May 2008

UGT2B7 promoter variant -840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease.

Am J Hematol 2008 Mar;83(3):200-2

Center for Cancer and Blood Disorders, Children's National Medical Center, Washington, DC 20010, USA.

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http://dx.doi.org/10.1002/ajh.21051DOI Listing
March 2008

Population pharmacokinetics of lamivudine in human immunodeficiency virus-exposed and -infected infants.

Antimicrob Agents Chemother 2007 Dec 24;51(12):4297-302. Epub 2007 Sep 24.

Division of Pharmacology and Drug Discovery, Pediatric Pharmacology Research Unit, University of California San Diego, MC 8214, San Diego, CA 92103-8214, USA.

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http://dx.doi.org/10.1128/AAC.00332-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168008PMC
December 2007

Pharmacokinetics of dexmedetomidine in postsurgical pediatric intensive care unit patients: preliminary study.

Pediatr Crit Care Med 2007 Sep;8(5):419-24

Rady Children's Hospital and Health Center and Presbyterian Healthcare Services, Albuquerque, NM 87125, USA.

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http://dx.doi.org/10.1097/01.PCC.0000282046.66773.39DOI Listing
September 2007

Pharmacologic, pharmacodynamic, and pharmacokinetic considerations with intravenous Ibuprofen lysine.

J Pediatr Pharmacol Ther 2007 Jul;12(3):158-70

University of California, San Diego, Division of Pharmacology and Drug Discovery, School of Medicine, Department of Pediatrics and Skagg's School of Pharmacy & Pharmaceutical Sciences, San Diego, California.

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http://dx.doi.org/10.5863/1551-6776-12.3.158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3462098PMC
July 2007