Edmund Capparelli

Edmund Capparelli

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Edmund Capparelli

Publications by authors named "Edmund Capparelli"

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Darunavir Pharmacokinetics With an Increased Dose During Pregnancy.

J Acquir Immune Defic Syndr 2020 Apr;83(4):373-380

Department of Clinical Pharmacy and Pediatrics, University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA.

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http://dx.doi.org/10.1097/QAI.0000000000002261DOI Listing
April 2020

Fosamprenavir with Ritonavir Pharmacokinetics during Pregnancy.

Antimicrob Agents Chemother 2020 Mar 24;64(4). Epub 2020 Mar 24.

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, California, USA.

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http://dx.doi.org/10.1128/AAC.02260-19DOI Listing
March 2020

Physiologically Based Pharmacokinetic Models to Predict Maternal Pharmacokinetics and Fetal Exposure to Emtricitabine and Acyclovir.

J Clin Pharmacol 2020 Feb 6;60(2):240-255. Epub 2019 Sep 6.

Pediatric Pharmacology and Pharmacometrics Research Center, University Children's Hospital Basel (UKBB), Basel, Switzerland.

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http://dx.doi.org/10.1002/jcph.1515DOI Listing
February 2020

Development and preclinical pharmacology of a novel dCK inhibitor, DI-87.

Biochem Pharmacol 2020 Feb 6;172:113742. Epub 2019 Dec 6.

Division of Hematology-Oncology, University of California San Diego, La Jolla, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2019.113742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981055PMC
February 2020

Population pharmacokinetic analysis of high-dose methotrexate in pediatric and adult oncology patients.

Cancer Chemother Pharmacol 2019 Dec 4;84(6):1339-1348. Epub 2019 Oct 4.

Division of Host-Microbe Systems and Therapeutics, University of California San Diego, 9500 Gilman Drive MC 0657, La Jolla, CA, 92093, USA.

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http://link.springer.com/10.1007/s00280-019-03966-4
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http://dx.doi.org/10.1007/s00280-019-03966-4DOI Listing
December 2019

Population pharmacokinetics of siltuximab: impact of disease state.

Cancer Chemother Pharmacol 2019 Nov 3;84(5):993-1001. Epub 2019 Sep 3.

Division of Host-Microbe Systems and Therapeutics, University of California San Diego, San Diego, CA, USA.

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http://dx.doi.org/10.1007/s00280-019-03939-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800650PMC
November 2019

Meropenem pharmacokinetics during relapsing peritonitis due to ESBL-producing Enterobacteriaciae in a liver transplant recipient.

Clin Case Rep 2019 Nov 30;7(11):2169-2173. Epub 2019 Sep 30.

Division of Infectious Diseases Department of Medical Subspecialties National Center for Child Health and Development Tokyo Japan.

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http://dx.doi.org/10.1002/ccr3.2398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878041PMC
November 2019

Using Mycobacterium tuberculosis Single-Nucleotide Polymorphisms To Predict Fluoroquinolone Treatment Response.

Antimicrob Agents Chemother 2019 07 24;63(7). Epub 2019 Jun 24.

Department of Medicine, University of California San Diego, La Jolla, California, USA

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http://dx.doi.org/10.1128/AAC.00076-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591594PMC
July 2019

Pharmacokinetics of Increased Nelfinavir Plasma Concentrations in Women During Pregnancy and Postpartum.

J Clin Pharmacol 2019 03 25;59(3):386-393. Epub 2018 Oct 25.

Division of Maternal Fetal Medicine, Department of Gynecology & Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/jcph.1331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368469PMC
March 2019

Sertraline Pharmacokinetics in HIV-Infected and Uninfected Children, Adolescents, and Young Adults.

Front Pediatr 2019 6;7:16. Epub 2019 Feb 6.

Department of Pediatrics-Rady Children's Hospital San Diego, University of California, San Diego, San Diego, CA, United States.

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http://dx.doi.org/10.3389/fped.2019.00016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372542PMC
February 2019

Infliximab Pharmacokinetics are Influenced by Intravenous Immunoglobulin Administration in Patients with Kawasaki Disease.

Clin Pharmacokinet 2018 12;57(12):1593-1601

Department of Pediatrics, University of California San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/s40262-018-0653-6DOI Listing
December 2018

Population Pharmacokinetics of Lopinavir/Ritonavir: Changes Across Formulations and Human Development From Infancy Through Adulthood.

J Clin Pharmacol 2018 12 25;58(12):1604-1617. Epub 2018 Sep 25.

Skaggs School of Pharmacy and Pharmaceutical Science, University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1002/jcph.1293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604805PMC
December 2018

Population Pharmacokinetics and Exploratory Exposure-Response Relationships of Diazepam in Children Treated for Status Epilepticus.

CPT Pharmacometrics Syst Pharmacol 2018 11 28;7(11):718-727. Epub 2018 Sep 28.

Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

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http://doi.wiley.com/10.1002/psp4.12349
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http://dx.doi.org/10.1002/psp4.12349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263663PMC
November 2018

Vincristine-associated Neuropathy With Antifungal Usage: A Kaiser Northern California Experience.

J Pediatr Hematol Oncol 2018 07;40(5):e273-e277

Division of Host-Microbe Systems and Therapeutics, University of California San Diego, San Diego.

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http://dx.doi.org/10.1097/MPH.0000000000001220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019195PMC
July 2018

Prevention and treatment of HIV infection in neonates: evidence base for existing WHO dosing recommendations and implementation considerations.

Expert Rev Clin Pharmacol 2018 Jan 8;11(1):83-93. Epub 2017 Nov 8.

b Department of Pediatrics , Boston University School of Medicine , Boston , MA , USA.

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http://dx.doi.org/10.1080/17512433.2018.1393331DOI Listing
January 2018

Persistent cytarabine and daunorubicin exposure after administration of novel liposomal formulation CPX-351: population pharmacokinetic assessment.

Cancer Chemother Pharmacol 2018 01 22;81(1):171-178. Epub 2017 Nov 22.

Division of Hematology-Oncology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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http://dx.doi.org/10.1007/s00280-017-3484-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756117PMC
January 2018

Development of Tolerance to Chronic Intermittent Furosemide Therapy in Pediatric Patients.

J Pediatr Pharmacol Ther 2017 Nov-Dec;22(6):394-398

Department of Clinical Pharmacy (GJK, GR, AHT), Rady Children's Hospital San Diego, California, Department of Pediatrics (EC, AHT), University of California, San Diego, Clinical and Translational Research Institute (JAP), University of California, San Diego.

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http://dx.doi.org/10.5863/1551-6776-22.6.394DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736250PMC
January 2018

External Evaluation of Two Fluconazole Infant Population Pharmacokinetic Models.

Antimicrob Agents Chemother 2017 12 22;61(12). Epub 2017 Nov 22.

Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

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http://dx.doi.org/10.1128/AAC.01352-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700313PMC
December 2017

Pharmacokinetics of single-dose ceftaroline fosamil in children with cystic fibrosis.

Pediatr Pulmonol 2017 Nov 14;52(11):1424-1434. Epub 2017 Sep 14.

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, La Jolla, California.

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http://dx.doi.org/10.1002/ppul.23827DOI Listing
November 2017

Population Pharmacokinetics of Dexmedetomidine in Infants.

J Clin Pharmacol 2017 09 25;57(9):1174-1182. Epub 2017 Apr 25.

Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.

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http://dx.doi.org/10.1002/jcph.904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561462PMC
September 2017

Population Pharmacokinetics and Exploratory Pharmacodynamics of Lorazepam in Pediatric Status Epilepticus.

Clin Pharmacokinet 2017 08;56(8):941-951

Department of Pediatrics and Skaggs School of Pharmacy, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0831, USA.

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http://dx.doi.org/10.1007/s40262-016-0486-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466505PMC
August 2017

Assessment of Nevirapine Prophylactic and Therapeutic Dosing Regimens for Neonates.

J Acquir Immune Defic Syndr 2017 08;75(5):554-560

*PHPT/IRD 174, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; †Department of Immunology and Infectious Diseases, Harvard T.H Chan School of Public Health, Boston, MA; ‡Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, United Kingdom; §Department of Pharmaceutical Care, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; ‖Institut d'Etudes Démographiques, Paris, France; ¶Institut de Recherche pour le Développement (IRD) UMI 174-PHPT, Marseille, France; #Department of Pharmaceutical Sciences, Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand; **Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA; ††Department of Pediatric, Health Promotion Center Region 10, Chiang Mai, Thailand; ‡‡Department of Pediatric, Banglamung Hospital, Chonburi, Thailand; §§Department of Pediatric, Nopparat Rajathanee Hospital, Bangkok, Thailand; ‖‖Department of Pediatric, Hat Yai Hospital, Hat Yai, Thailand; ¶¶Department of Pediatric, Samutprakarn Hospital, Samut Prakan, Thailand; ##Manchester Pharmacy School, The University of Manchester, Manchester, United Kingdom; and ***EAU7323 Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1097/QAI.0000000000001447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508655PMC
August 2017

Population pharmacokinetics analysis of VRC01, an HIV-1 broadly neutralizing monoclonal antibody, in healthy adults.

MAbs 2017 07 3;9(5):792-800. Epub 2017 Apr 3.

a Vaccine and Infectious Disease Division, Public Health Division , Fred Hutchinson Cancer Research Center , Seattle , WA , USA.

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http://dx.doi.org/10.1080/19420862.2017.1311435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524155PMC
July 2017

Utility of Spot Urine Specimens to Assess Tubular Secretion.

Am J Kidney Dis 2017 May 8;69(5):709-711. Epub 2017 Mar 8.

University of California San Diego, San Diego, California. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2016.12.016DOI Listing
May 2017

CYP2B6 genotype-directed dosing is required for optimal efavirenz exposure in children 3-36 months with HIV infection.

AIDS 2017 05;31(8):1129-1136

aCentre for Infectious Disease Research in Zambia, Lusaka, Zambia bUniversity of Alabama at Birmingham, Birmingham, Alabama cUniversity of California San Diego, La Jolla dRady Children's Hospital, San Diego, California eHarvard T.H. Chan School of Public Health, Boston, Massachusetts, USA fUniversity of Zimbabwe, Harare, Zimbabwe gNational Institutes of Allergy and Infectious Diseases hEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland iFrontier Science and Technology Research Foundation, Amherst jNew York University's School of Medicine, New York, New York kUNC Global Health and Infectious Diseases, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina lSocial and Scientific Systems Inc, Silver Springs, Maryland, USA mBARC-SA and Lancet Laboratories, Johannesburg, South Africa nNorthwestern University's Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1097/QAD.0000000000001463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623109PMC
May 2017

Phase I Clinical Trial Results of Auranofin, a Novel Antiparasitic Agent.

Antimicrob Agents Chemother 2017 01 27;61(1). Epub 2016 Dec 27.

Departments of Pathology and Medicine, University of California, San Diego, School of Medicine, La Jolla, California, USA

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http://dx.doi.org/10.1128/AAC.01947-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192119PMC
January 2017

Electronic Health Records and Pharmacokinetic Modeling to Assess the Relationship between Ampicillin Exposure and Seizure Risk in Neonates.

J Pediatr 2016 Nov 10;178:125-129.e1. Epub 2016 Aug 10.

Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Department of Pediatrics, Duke University School of Medicine, Durham, NC.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085855PMC
http://dx.doi.org/10.1016/j.jpeds.2016.07.011DOI Listing
November 2016

Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption.

N Engl J Med 2016 11 9;375(21):2037-2050. Epub 2016 Nov 9.

From the University of Pennsylvania (K.J.B., D.B.S., B.S., G.H.L., E.F.K., M.B., J.A.H., P.T.) and Children's Hospital of Philadelphia (N.B.T.) - both in Philadelphia; the Laboratory of Immunoregulation (M.C.S., J.S.J., M.E.P., J.B., E.W.R., K.E.C., S.M., A.S.F., T.-W.C.), Biostatistics Research Branch (M.A.P.), Vaccine Research Center (P.J.M., S.J.O., A.R.S., N.A.D.-R., R.T.B., J.E.L., R.M.L., B.S.G., R.A.K., J.R.M.), and Division of AIDS (R.L.T.), National Institute of Allergy and Infectious Diseases and National Institutes of Health (NIH), and the Critical Care Medicine Department, Clinical Center, NIH (C.A.S., R.W.K.), Bethesda, the AIDS Clinical Trials Group, Silver Spring (K.O.), and Columbus Technologies and Services, Greenbelt (R.L.T.) - all in Maryland; Harvard T.H. Chan School of Public Health, Boston (L.J.H.); the University of Alabama at Birmingham, Birmingham (E.T.O., M.M.); Frontier Science and Technology Research Foundation, Amherst, NY (B.J.); and the University of California, San Diego, La Jolla (E.V.C.).

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http://dx.doi.org/10.1056/NEJMoa1608243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292134PMC
November 2016

Association of concurrent acid-suppression therapy with survival outcomes and adverse event incidence in oncology patients receiving erlotinib.

Cancer Chemother Pharmacol 2016 Aug 2;78(2):427-32. Epub 2016 Jul 2.

Center for Personalized Cancer Therapy and Division of Hematology and Oncology, Moores Cancer Center, UC San Diego Health System, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/s00280-016-3087-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967016PMC
August 2016

Pharmacokinetics of Rilpivirine in HIV-Infected Pregnant Women.

J Acquir Immune Defic Syndr 2016 07;72(3):289-96

*Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA; †Skaggs School of Pharmacy and Pharmaceutical Sciences, Pediatrics Department-Rady Children's Hospital, University of California, San Diego, CA; ‡Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA; §Department of Biostatistics, Harvard School of Public Health, Boston, MA; ‖Department of Medicine, Children's Hospital Boston, Boston, MA; ¶Irmandade da Santa Casa de Misericordia de Porto Alegre, HIV/AIDS Research Department, Porto Alegre, Brazil; #Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; **FHI 360, IMPAACT Operations Office, Durham, NC; ††Program for HIV Prevention and Treatment, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; ‡‡Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health, DHHS, Bethesda, MD; §§National Institute of Allergy and Infectious Diseases, Bethesda, MD; and ‖‖Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911231PMC
July 2016

A randomized controlled trial of gabapentin for chronic low back pain with and without a radiating component.

Pain 2016 07;157(7):1499-507

aVA San Diego Healthcare System, San Diego, CA, USA bDepartment of Psychiatry, University of California, San Diego, La Jolla, CA, USA cScottsdale Healthcare Research Institute, Scottsdale, AZ, USA dDepartment of Pediatrics, University of California, San Diego, La Jolla, CA, USA eComputational and Applied Statistics Laboratory, University of California, San Diego, La Jolla, CA, USA Departments of fMathematics, gAnesthesiology, and hOrthopaedic Surgery, University of California, San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1097/j.pain.0000000000000554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001843PMC
July 2016

Pharmacokinetics, Safety and Tolerability of Single Oral or Intravenous Administration of 200 mg Tedizolid Phosphate in Adolescents.

Pediatr Infect Dis J 2016 06;35(6):628-33

From the *Department of Pediatrics, University of California, San Diego, California; †Rady Children's Hospital, San Diego, California; ‡Clinical Development Merck & Co., Inc., Kenilworth, New Jersey; §Division of Infectious Diseases Children's Hospital of Orange County, Orange California; and ¶Department of Pediatrics, Arkansas Children's Hospital, Little Rock, Arkansas.

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http://dx.doi.org/10.1097/INF.0000000000001096DOI Listing
June 2016

Population Pharmacokinetic Assessment and Pharmacodynamic Implications of Pediatric Cefepime Dosing for Susceptible-Dose-Dependent Organisms.

Antimicrob Agents Chemother 2016 Apr 25;60(4):2150-6. Epub 2016 Mar 25.

Center for Research in Pediatric and Developmental Pharmacology, University of California, San Diego, La Jolla, and Rady Children's Hospital, San Diego, California, USA

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http://dx.doi.org/10.1128/AAC.02592-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808231PMC
April 2016

Lopinavir/ritonavir plus lamivudine and abacavir or zidovudine dose ratios for paediatric fixed-dose combinations.

Antivir Ther 2015 3;20(2):225-33. Epub 2014 Oct 3.

EA 7323, Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.3851/IMP2876DOI Listing
January 2016

Pharmacodynamic Characteristics of Nephrotoxicity Associated With Vancomycin Use in Children.

J Pediatric Infect Dis Soc 2015 Dec 3;4(4):e109-16. Epub 2014 Nov 3.

San Diego School of Medicine, La Jolla Rady Children's Hospital San Diego, California.

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http://dx.doi.org/10.1093/jpids/piu110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681388PMC
December 2015

Pharmacokinetics of Once Versus Twice Daily Darunavir in Pregnant HIV-Infected Women.

J Acquir Immune Defic Syndr 2015 Sep;70(1):33-41

*Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Southern California School of Medicine, Los Angeles, CA; †Department of Biostatistics, Statistical and Data Analysis Center, Harvard School of Public Health, Boston, MA; ‡Department of Medicine, Children's Hospital Boston, Boston, MA; §HIV/AIDS Research Department, Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil; ‖Research Institute for Health Sciences, Chiang Mai University, Chiang Mai, Thailand; ¶Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; #Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, DHHS, Bethesda, MD; **National Institute of Allergy and Infectious Diseases, Bethesda, MD; and ††Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579345PMC
September 2015

Fluconazole population pharmacokinetics and dosing for prevention and treatment of invasive Candidiasis in children supported with extracorporeal membrane oxygenation.

Antimicrob Agents Chemother 2015 Jul 20;59(7):3935-43. Epub 2015 Apr 20.

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, USA Duke Clinical Research Institute, Duke University Medical Center, Durham, North Carolina, USA

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http://dx.doi.org/10.1128/AAC.00102-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468733PMC
July 2015

Bayesian Estimation of Vancomycin Pharmacokinetics in Obese Children: Matched Case-Control Study.

Clin Ther 2015 Jun 29;37(6):1340-51. Epub 2015 May 29.

University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences and School of Medicine, La Jolla, California; Rady Children's Hospital of San Diego, San Diego, California.

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http://dx.doi.org/10.1016/j.clinthera.2015.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475435PMC
June 2015

Auranofin is highly efficacious against Toxoplasma gondii in vitro and in an in vivo experimental model of acute toxoplasmosis.

PLoS Negl Trop Dis 2014 31;8(7):e2973. Epub 2014 Jul 31.

Department of Medicine, University of California, San Diego, San Diego, California, United States of America; Department of Pathology, University of California, San Diego, San Diego, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0002973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117455PMC
March 2015

Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing.

Cancer Chemother Pharmacol 2015 Mar 4;75(3):495-503. Epub 2015 Jan 4.

University of California San Diego, 9500 Gilman Drive, MC 0657, La Jolla, CA, 92093-0657, USA.

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http://dx.doi.org/10.1007/s00280-014-2667-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344382PMC
March 2015

Adverse Event Detection and Labeling in Pediatric Drug Development: Antiretroviral Drugs.

Ther Innov Regul Sci 2015 Mar;49(2):302-309

4 Office of Clinical Pharmacology, Office of Translational Sciences, US Food and Drug Administration, Silver Spring, MD, USA.

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http://dx.doi.org/10.1177/2168479014565471DOI Listing
March 2015

The effect of malnutrition on the pharmacokinetics and virologic outcomes of lopinavir, efavirenz and nevirapine in food insecure HIV-infected children in Tororo, Uganda.

Pediatr Infect Dis J 2015 Mar;34(3):e63-70

From the Department of *Clinical Pharmacy, †Bioengineering & Therapeutic Sciences, ‡Medicine, and §Pediatrics, and ¶Center for AIDS Prevention Studies of the University of California, San Francisco, CA; ‖Department of Pediatric Immunology and Infectious Diseases, Emma Children's Hospital AMC, The Netherlands; **University of California San Diego, La Jolla, CA; ††Department of Pharmacology, Hôpital Européen Georges Pompidou, Paris Descartes, France; ‡‡Division of Nutritional Sciences, Cornell University, Ithaca, NY; and Departments of §§Pediatrics and Child Health, and ¶¶Medicine, Makerere University, Kampala, Uganda.

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http://dx.doi.org/10.1097/INF.0000000000000603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351793PMC
March 2015

Optimizing pediatric esmolol dosing using computerized practitioner order entry.

J Pediatr Pharmacol Ther 2014 Oct-Dec;19(4):302-9

University of California, San Diego, School of Medicine, San Diego, California ; University of California, San Diego, Skaggs School of Pharmacy, San Diego, California.

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http://dx.doi.org/10.5863/1551-6776-19.4.302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341416PMC
March 2015

Raltegravir pharmacokinetics during pregnancy.

J Acquir Immune Defic Syndr 2014 Dec;67(4):375-81

*Office of the Global AIDS Coordinator, U.S. Department of State, Washington, DC; †Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, CA; ‡Department of Pediatrics and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, CA; §Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA; ‖Program for HIV Prevention and Treatment (IRD URI 174), Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; ¶Department of Clinical Pharmacy, Drug Research Unit, University of California, San Francisco, San Francisco, CA; #HIV/AIDS Research Department, Irmandade da Santa Casa de Misericordia de Porto Alegre, Porto Alegre, Brazil; **Boston Children's Hospital, Harvard Medical School, Boston, MA; ††Social and Scientific Systems, Inc, Silver Spring, MD; ‡‡Maternal, Adolescent, and Pediatric Research Branch, National Institute of Allergy and Infectious Diseases, Bethesda, MD; and §§Department of Pediatrics, Boston University School of Medicine, Boston, MA.

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http://dx.doi.org/10.1097/QAI.0000000000000318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213295PMC
December 2014

Vancomycin cerebrospinal fluid pharmacokinetics in children with cerebral ventricular shunt infections.

Pediatr Infect Dis J 2014 Oct;33(10):e270-2

From the *Duke Clinical Research Institute; †Department of Pediatrics, Duke University, Durham; ‡Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC; §Department of Pediatric Pharmacology, University of California, San Diego, CA; and ¶Department of Neurosurgery, Duke University, Durham, NC.

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http://dx.doi.org/10.1097/INF.0000000000000385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209191PMC
October 2014

Predictive performance of a gentamicin population pharmacokinetic model in neonates receiving full-body hypothermia.

Ther Drug Monit 2014 Oct;36(5):584-9

*Duke Clinical Research Institute, Durham; †Department of Pharmacotherapy and Experiment Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC; ‡Department of Pediatrics, Stanford University, Palo Alto, CA; §Department of Pediatrics, Duke University Medical Center, Durham, NC; ¶Schools of Medicine and Pharmacy, University of California San Diego, La Jolla; and ‖Department of Pediatrics, University of California, San Francisco.

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http://dx.doi.org/10.1097/FTD.0000000000000056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4166612PMC
October 2014

Variable and suboptimal nevirapine levels in infants given single-dose nevirapine at birth without maternal prophylaxis.

AIDS 2014 Oct;28(16):2491-3

aSeattle Children's Research Institute bUniversity of Washington, Seattle, Washington cUniversity of California San Diego, San Diego, California dHealth Alliance International, Seattle, Washington, USA eHealth Alliance International, Beira, Mozambique fUniversity of Wisconsin-Madison, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000451DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4332529PMC
October 2014

Vancomycin monitoring in children using bayesian estimation.

Ther Drug Monit 2014 Aug;36(4):510-8

*Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla; †Miller Children's Hospital, Long Beach; and ‡Rady Children's Hospital, San Diego, CA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101060PMC
http://dx.doi.org/10.1097/FTD.0000000000000039DOI Listing
August 2014

Population pharmacokinetics of intravenous acyclovir in preterm and term infants.

Pediatr Infect Dis J 2014 Jan;33(1):42-9

From the *Duke Clinical Research Institute, Durham; †University of North Carolina, Eshelman School of Pharmacy, Chapel Hill, NC; ‡Wichita Medical Research and Education Foundation, Wichita, KS; §EMMES Corporation, Rockville, MD; and ¶University of California-San Diego, Schools of Medicine and Pharmacy, La Jolla, CA.

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http://dx.doi.org/10.1097/01.inf.0000435509.75114.3dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904301PMC
January 2014

Reduced indinavir exposure during pregnancy.

Br J Clin Pharmacol 2013 Sep;76(3):475-83

Program for HIV Prevention and Treatment (IRD URI 174), Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand; Harvard School of Public Health, Boston, MA, USA; Institut de Recherché pour le Développement (IRD), UMI 174-PHPT, Marseille, France.

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http://doi.wiley.com/10.1111/bcp.12078
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http://dx.doi.org/10.1111/bcp.12078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769674PMC
September 2013

Determining population and developmental pharmacokinetics of metronidazole using plasma and dried blood spot samples from premature infants.

Pediatr Infect Dis J 2013 Sep;32(9):956-61

From the *Department of Pediatrics, Duke University; †Duke Clinical Research Institute, Durham, NC; ‡Wichita Medical Research and Education Foundation, Wichita, KS; §Division of Infectious Diseases, CHOC-Children's Hospital of Orange County, Orange, CA; ¶Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Vanderbilt University Medical Center, Nashville, TN; ‖EMMES Corporation, Rockville, MD; **Department of Pediatrics, University of Missouri-Kansas City School of Medicine and the Division of Pediatric Pharmacology and Therapeutic Innovation, The Children's Mercy Hospital, Kansas City, MO; ††Department of Pediatric Pharmacology, University of California, San Diego, CA; and ‡‡Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD.

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https://insights.ovid.com/crossref?an=00006454-201309000-000
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http://dx.doi.org/10.1097/INF.0b013e3182947cf8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769518PMC
September 2013

Etravirine in CSF is highly protein bound.

J Antimicrob Chemother 2013 May 20;68(5):1161-8. Epub 2013 Jan 20.

Department of Pediatrics (Rady Children's Hospital), University of California San Diego, 3020 Childrens Way, San Diego, CA 92123, USA.

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http://dx.doi.org/10.1093/jac/dks517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625433PMC
May 2013

Determination of efavirenz in human dried blood spots by reversed-phase high-performance liquid chromatography with UV detection.

Ther Drug Monit 2013 Apr;35(2):203-8

Skagg's School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA 92093-0831, USA.

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http://dx.doi.org/10.1097/FTD.0b013e31827fb72bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848783PMC
April 2013