Edi Brogi

Edi Brogi

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Edi Brogi

Edi Brogi

Publications by authors named "Edi Brogi"

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Automatic quantification of gene amplification in invasive breast cancer from chromogenic hybridization whole slide images.

J Med Imaging (Bellingham) 2019 Oct 21;6(4):047501. Epub 2019 Nov 21.

Memorial Sloan Kettering Cancer Center, Department of Pathology, New York, New York, United States.

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http://dx.doi.org/10.1117/1.JMI.6.4.047501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868351PMC
October 2019

Is Sentinel Lymph Node Biopsy Required for a Core Biopsy Diagnosis of Ductal Carcinoma In Situ with Microinvasion?

Ann Surg Oncol 2019 Sep 30;26(9):2738-2746. Epub 2019 May 30.

Breast Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1245/s10434-019-07475-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684408PMC
September 2019

Secretory carcinoma of the breast: clinicopathologic profile of 14 cases emphasising distant metastatic potential.

Histopathology 2019 Aug 10;75(2):213-224. Epub 2019 Jul 10.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1111/his.13879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646069PMC
August 2019

Clinical-grade computational pathology using weakly supervised deep learning on whole slide images.

Nat Med 2019 08 15;25(8):1301-1309. Epub 2019 Jul 15.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41591-019-0508-1DOI Listing
August 2019

Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization.

Elife 2019 03 26;8. Epub 2019 Mar 26.

Cancer Biology and Genetics Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, United States.

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http://dx.doi.org/10.7554/eLife.43627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440742PMC
March 2019

Reply to "Multicentric Ipsilateral Invasive Breast Carcinomas Might Have Higher 21-Gene Recurrence Score Compared with Multifocal Ipsilateral Invasive Breast Carcinomas".

Ann Surg Oncol 2019 01 19;26(1):310-311. Epub 2018 Nov 19.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1245/s10434-018-7078-1DOI Listing
January 2019

Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway.

Cancer Cell 2018 12;34(6):893-905.e8

Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center (MSKCC), New York, NY 10065, USA; Breast Medicine Service, Department of Medicine, MSKCC, New York, NY 10065, USA; Weill-Cornell Medical College, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108183052
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http://dx.doi.org/10.1016/j.ccell.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294301PMC
December 2018

The 21-Gene Recurrence Score in Male Breast Cancer.

Ann Surg Oncol 2018 Jun 8;25(6):1530-1535. Epub 2018 Mar 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1245/s10434-018-6411-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930124PMC
June 2018

Lobular Carcinoma In Situ.

Surg Pathol Clin 2018 Mar 8;11(1):123-145. Epub 2017 Dec 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.path.2017.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841603PMC
March 2018

Monosomy 17 in potentially curable HER2-amplified breast cancer: prognostic and predictive impact.

Breast Cancer Res Treat 2018 01 6;167(2):547-554. Epub 2017 Oct 6.

Cedars-Sinai Medical Center, 8700 Beverly Blvd, AC 1042B, Los Angeles, CA, 90048, USA.

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http://dx.doi.org/10.1007/s10549-017-4520-1DOI Listing
January 2018

Breast carcinoma with 21-gene recurrence score lower than 18: rate of locoregional recurrence in a large series with clinical follow-up.

BMC Cancer 2018 01 6;18(1):42. Epub 2018 Jan 6.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

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http://dx.doi.org/10.1186/s12885-017-3985-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756373PMC
January 2018

Tumor Heterogeneity in Breast Cancer.

Front Med (Lausanne) 2017 8;4:227. Epub 2017 Dec 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, United States.

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http://dx.doi.org/10.3389/fmed.2017.00227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727049PMC
December 2017

Benign vascular lesions of the breast diagnosed by core needle biopsy do not require excision.

Histopathology 2017 Nov 8;71(5):795-804. Epub 2017 Sep 8.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1111/his.13291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5708168PMC
November 2017

21-Gene recurrence score and locoregional recurrence in lymph node-negative, estrogen receptor-positive breast cancer.

Breast Cancer Res Treat 2017 Nov 12;166(1):69-76. Epub 2017 Jul 12.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s10549-017-4381-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647226PMC
November 2017

Specimen Identification Errors in Breast Biopsies: Age Matters. Report of Two Near-Miss Events and Review of the Literature.

Breast J 2017 Sep 16;23(5):583-588. Epub 2017 Mar 16.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York City, New York.

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http://dx.doi.org/10.1111/tbj.12797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600634PMC
September 2017

The 21-gene recurrence score in special histologic subtypes of breast cancer with favorable prognosis.

Breast Cancer Res Treat 2017 Aug 3;165(1):65-76. Epub 2017 Jun 3.

Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s10549-017-4326-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572649PMC
August 2017

Fibroepithelial Lesions in the Breast of Adolescent Females: A Clinicopathological Study of 54 Cases.

Breast J 2017 Mar 4;23(2):182-192. Epub 2016 Nov 4.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1111/tbj.12706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356480PMC
March 2017

Estimating the OncotypeDX score: validation of an inexpensive estimation tool.

Breast Cancer Res Treat 2017 02 7;161(3):435-441. Epub 2016 Dec 7.

Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 300 East 66th Street, New York, NY, 10065, USA.

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http://dx.doi.org/10.1007/s10549-016-4069-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310948PMC
February 2017

The 2015 Fred W. Stewart Award: Robert H. Young, MD.

Am J Surg Pathol 2016 Oct;40(10):1435-1436

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/PAS.0000000000000718DOI Listing
October 2016

PDK1-SGK1 Signaling Sustains AKT-Independent mTORC1 Activation and Confers Resistance to PI3Kα Inhibition.

Cancer Cell 2016 08 21;30(2):229-242. Epub 2016 Jul 21.

Human Oncology & Pathogenesis Program (HOPP), Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA; Department of Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 20, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982440PMC
August 2016

Sentinel Lymph Nodes for Breast Carcinoma: A Paradigm Shift.

Arch Pathol Lab Med 2016 Aug;140(8):791-8

From the Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://www.archivesofpathology.org/doi/10.5858/arpa.2015-014
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http://dx.doi.org/10.5858/arpa.2015-0140-RADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027875PMC
August 2016

Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling.

Cell 2016 Jun;166(1):47-62

Cell Biology Program and Center for Metastasis Research, Sloan Kettering Institute for Cancer Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Department of Cancer Biology and David H. Koch Center for Applied Research of Genitourinary Cancers, UT MD Anderson Cancer Center, Houston, TX 77054, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980842PMC
June 2016

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss.

Genes Dev 2016 Jan 23;30(1):34-51. Epub 2015 Dec 23.

Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA; Molecular and Cellular Biology Program, Stony Brook University, Stony Brook, New York 11790, USA;

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http://dx.doi.org/10.1101/gad.270959.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701977PMC
January 2016

Sentinel lymph nodes for breast carcinoma: an update on current practice.

Histopathology 2016 Jan;68(1):152-67

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1111/his.12853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027880PMC
January 2016

Gene expression profiling of lobular carcinoma in situ reveals candidate precursor genes for invasion.

Mol Oncol 2015 Apr 24;9(4):772-82. Epub 2014 Dec 24.

Breast Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 300 E. 66th St., New York, NY, 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molonc.2014.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387062PMC
April 2015

Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S.

Nat Cell Biol 2014 Sep 3;16(9):876-88. Epub 2014 Aug 3.

1] Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [3] Metastasis Research Center, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1038/ncb3011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249762PMC
September 2014

In search of the ideal immunopanel to distinguish metastatic mammary carcinoma from primary lung carcinoma: a tissue microarray study of 207 cases.

Appl Immunohistochem Mol Morphol 2014 Apr;22(4):266-74

Departments of *Pathology and Laboratory Medicine ‡Public Health, Division of Biostatistics and Epidemiology, Weill Cornell Medical College †Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/PAI.0b013e318297cc0bDOI Listing
April 2014

Cancelled stereotactic biopsy of calcifications not seen using the stereotactic technique: do we still need to biopsy?

Eur Radiol 2014 Apr 12;24(4):907-12. Epub 2013 Nov 12.

Departments of Radiology, Memorial Sloan-Kettering Cancer Center, Evelyn H. Lauder Breast Center, 300 East 66th Street, # 731, New York, NY, 10065, USA,

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http://dx.doi.org/10.1007/s00330-013-3055-zDOI Listing
April 2014

Serpins promote cancer cell survival and vascular co-option in brain metastasis.

Cell 2014 Feb;156(5):1002-16

Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Metastasis Research Center, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.01.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988473PMC
February 2014

TGF-β-Id1 signaling opposes Twist1 and promotes metastatic colonization via a mesenchymal-to-epithelial transition.

Cell Rep 2013 Dec;5(5):1228-42

Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, 415 East 68(th) Street, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891470PMC
December 2013

Focal extravasated mucin in breast core needle biopsies: is surgical excision always necessary?

Breast J 2013 May-Jun;19(3):302-9. Epub 2013 Mar 28.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York City, NY, USA.

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http://dx.doi.org/10.1111/tbj.12104DOI Listing
November 2013

Safety and efficacy of radioactive seed localization with I-125 prior to lumpectomy and/or excisional biopsy.

Eur J Radiol 2013 Sep 14;82(9):1453-7. Epub 2013 May 14.

Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, United States.

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http://dx.doi.org/10.1016/j.ejrad.2013.04.008DOI Listing
September 2013

Selection of bone metastasis seeds by mesenchymal signals in the primary tumor stroma.

Cell 2013 Aug;154(5):1060-1073

Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Chevy Chase, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2013.07.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3974915PMC
August 2013

Ductal carcinoma in situ: morphology-based knowledge and molecular advances.

Adv Anat Pathol 2013 Jul;20(4):205-16

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1097/PAP.0b013e3182976ed5DOI Listing
July 2013

Classic lobular carcinoma in situ and atypical lobular hyperplasia at percutaneous breast core biopsy: outcomes of prospective excision.

Cancer 2013 Mar 6;119(5):1073-9. Epub 2012 Nov 6.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1002/cncr.27841DOI Listing
March 2013

Non-mammary metastases to the breast and axilla: a study of 85 cases.

Mod Pathol 2013 Mar 23;26(3):343-9. Epub 2012 Nov 23.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://www.nature.com/articles/modpathol2012191
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http://dx.doi.org/10.1038/modpathol.2012.191DOI Listing
March 2013

Should breast density influence patient selection for breast-conserving surgery?

Ann Surg Oncol 2013 Feb 1;20(2):600-6. Epub 2012 Sep 1.

Breast Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 300 E. 66th St., New York, NY, USA.

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http://dx.doi.org/10.1245/s10434-012-2604-zDOI Listing
February 2013

DNA mismatch repair deficiency in breast carcinoma: a pilot study of triple-negative and non-triple-negative tumors.

Am J Surg Pathol 2012 Nov;36(11):1700-8

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1097/PAS.0b013e3182627787DOI Listing
November 2012

Papilloma diagnosed at MRI-guided vacuum-assisted breast biopsy: is surgical excision still warranted?

AJR Am J Roentgenol 2012 Oct;199(4):W512-9

Department of Radiology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA.

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http://dx.doi.org/10.2214/AJR.12.8750DOI Listing
October 2012

Id4 protein is highly expressed in triple-negative breast carcinomas: possible implications for BRCA1 downregulation.

Breast Cancer Res Treat 2012 Aug 27;135(1):93-102. Epub 2012 Apr 27.

Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.

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http://dx.doi.org/10.1007/s10549-012-2070-0DOI Listing
August 2012

The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites.

Cell 2012 Aug;150(4):764-79

Cell Biology Program, Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.cell.2012.06.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711709PMC
August 2012

Cadherin-catenin complex dissociation in lobular neoplasia of the breast.

Breast Cancer Res Treat 2012 Apr 13;132(2):641-52. Epub 2011 Nov 13.

Breast Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 300 E. 66th St., New York, NY 10065, USA.

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http://dx.doi.org/10.1007/s10549-011-1860-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349355PMC
April 2012

Synchronous breast cancers with different morphologic and molecular phenotypes occurring in Lynch syndrome: what does the heterogeneity imply?

Am J Surg Pathol 2011 Nov;35(11):1743-8

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1097/PAS.0b013e3182320cffDOI Listing
November 2011

The need to examine metastatic tissue at the time of progression of breast cancer: is re-biopsy a necessity or a luxury?

Curr Oncol Rep 2011 Feb;13(1):17-25

Evelyn H. Lauder Breast and Imaging Center, Memorial Sloan-Kettering Cancer Center, 300 East 66th Street, New York, NY 10065, USA.

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http://dx.doi.org/10.1007/s11912-010-0137-9DOI Listing
February 2011

Lobular carcinoma, not only a classic.

Breast J 2010 Sep-Oct;16 Suppl 1:S10-4

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.

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http://dx.doi.org/10.1111/j.1524-4741.2010.00994.xDOI Listing
February 2011

Challenges in the interpretation of breast core biopsies.

Breast J 2010 Sep-Oct;16 Suppl 1:S5-9

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

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http://dx.doi.org/10.1111/j.1524-4741.2010.00993.xDOI Listing
February 2011

Nomogram for predicting the risk of local recurrence after breast-conserving surgery for ductal carcinoma in situ.

J Clin Oncol 2010 Aug 12;28(23):3762-9. Epub 2010 Jul 12.

Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1200/JCO.2009.26.8847DOI Listing
August 2010

Endosalpingiosis in axillary lymph nodes: a possible pitfall in the staging of patients with breast carcinoma.

Am J Surg Pathol 2010 Aug;34(8):1211-6

Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1097/PAS.0b013e3181e5e03eDOI Listing
August 2010

Subtle variations in Pten dose determine cancer susceptibility.

Nat Genet 2010 May 18;42(5):454-8. Epub 2010 Apr 18.

Cancer Genetics Program, Department of Medicine, Beth Israel Deaconess Cancer Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://www.nature.com/articles/ng.556
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http://dx.doi.org/10.1038/ng.556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118559PMC
May 2010