Publications by authors named "Edgar Faber"

61Publications

NFKB1 gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.

Ann Hematol 2020 Mar 30;99(3):609-618. Epub 2020 Jan 30.

Department of Hemato-Oncology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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http://dx.doi.org/10.1007/s00277-020-03935-5DOI Listing
March 2020

Allogeneic Stem Cell Transplantation in Patients With FLT3-ITD Mutated AML: Transplantation in CR1 Is the Decisive Factor for Good Outcome.

Clin Lymphoma Myeloma Leuk 2019 07 19;19(7):462-469. Epub 2019 Apr 19.

Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.clml.2019.04.005DOI Listing
July 2019

First-line imatinib in elderly patients with chronic myeloid leukaemia from the CAMELIA registry: Age and dose still matter.

Leuk Res 2019 06 24;81:67-74. Epub 2019 Apr 24.

Department of Haemato- Oncology, Faculty Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.leukres.2019.04.011DOI Listing
June 2019

Granulocyte transfusions collected after steroid priming for severe infections during neutropenia: A single center experience.

Transfus Clin Biol 2019 Nov 6;26(4):299-303. Epub 2018 Oct 6.

Department of Hemato-oncology, Faculty Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, I.P. Pavlova 6, 77520 Olomouc, Czech Republic. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S12467820183027
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http://dx.doi.org/10.1016/j.tracli.2018.09.001DOI Listing
November 2019

Insulin resistance is an underlying mechanism of impaired glucose metabolism during nilotinib therapy.

Am J Hematol 2018 10 31;93(10):E342-E345. Epub 2018 Aug 31.

Department of Internal Medicine, Hematology and Oncology, Masaryk University and University Hospital Brno, Brno, Czech Republic.

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http://dx.doi.org/10.1002/ajh.25232DOI Listing
October 2018

Novel sulphur-containing imatinib metabolites found by untargeted LC-HRMS analysis.

Eur J Pharm Sci 2017 Jun 20;104:335-343. Epub 2017 Apr 20.

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc, Hněvotínská 5, 779 00 Olomouc, Czech Republic; Laboratory for Inherited Metabolic Disorders, Faculty of Medicine and Dentistry, Palacký University Olomouc, I. P. Pavlova 6, 775 20 Olomouc, Czech Republic; Department of Clinical Biochemistry, University Hospital Olomouc, I. P. Pavlova 6, 775 20 Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.ejps.2017.04.014DOI Listing
June 2017

Metabolite Profiling of the Plasma and Leukocytes of Chronic Myeloid Leukemia Patients.

J Proteome Res 2016 09 9;15(9):3158-66. Epub 2016 Aug 9.

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacký University Olomouc , Hněvotínská 5, 779 00 Olomouc, Czech Republic.

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http://dx.doi.org/10.1021/acs.jproteome.6b00356DOI Listing
September 2016

Ultrafast Online SPE-MS/MS Method for Quantification of 3 Tyrosine Kinase Inhibitors in Human Plasma.

Ther Drug Monit 2016 08;38(4):516-24

*Laboratory of Metabolomics, Institute of Molecular and Translational Medicine; †Laboratory of Inherited Metabolic Disorders; ‡Department of Hemato-Oncology; §Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University in Olomouc; and ¶Department of Clinical Biochemistry, University Hospital Olomouc, Czech Republic.

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http://dx.doi.org/10.1097/FTD.0000000000000309DOI Listing
August 2016

[Targeted treatment of chronic myeloid leukemia in the elderly patients].

Authors:
Edgar Faber

Vnitr Lek 2015 Sep;61(9):758-9

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September 2015

Detailed study of imatinib metabolization using high-resolution mass spectrometry.

J Chromatogr A 2015 Aug 13;1409:173-81. Epub 2015 Jul 13.

Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University in Olomouc, Czech Republic; Laboratory for Inherited Metabolic Disorders, Faculty of Medicine and Dentistry, Palacky University in Olomouc, University Hospital Olomouc, Czech Republic; Department of Clinical Chemistry, University Hospital Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.chroma.2015.07.033DOI Listing
August 2015

A lower dosage of imatinib is sufficient to maintain undetectable disease in patients with chronic myeloid leukemia with long-term low-grade toxicity of the treatment.

Leuk Lymphoma 2016 Feb 22;57(2):370-375. Epub 2015 Jun 22.

a Department of Hemato-Oncology , University Hospital and Faculty of Medicine and Dentistry, Palacky University , Olomouc , Czech Republic.

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http://dx.doi.org/10.3109/10428194.2015.1056184DOI Listing
February 2016

ATM gene single nucleotide polymorphisms predict regimen-related gastrointestinal toxicity in patients allografted after reduced conditioning.

Biol Blood Marrow Transplant 2015 Jun 7;21(6):1136-40. Epub 2015 Mar 7.

Department of Hemato-Oncology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.bbmt.2015.02.021DOI Listing
June 2015

Comparison of reduced conditionings combining fludarabine with melphalan or 3-day busulfan in patients allografted for myeloid neoplasms.

Int J Hematol 2014 Dec 11;100(6):582-91. Epub 2014 Oct 11.

Department of Hemato-Oncology, University Hospital and Faculty of Medicine and Dentistry, Palacky University, I. P. Pavlova 6, 775 20, Olomouc, Czech Republic,

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http://link.springer.com/content/pdf/10.1007%2Fs12185-014-16
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http://link.springer.com/10.1007/s12185-014-1684-x
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http://dx.doi.org/10.1007/s12185-014-1684-xDOI Listing
December 2014

Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-α monotherapy.

PLoS One 2014 31;9(1):e87794. Epub 2014 Jan 31.

Hematology Research Unit Helsinki, Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0087794PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909235PMC
October 2014

Spontaneous splenic rupture in a patient with acute promyelocytic leukaemia during induction chemotherapy.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2015 Jun 26;159(2):294-8. Epub 2013 Nov 26.

Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2013.086DOI Listing
June 2015

Reduced relative dose intensity of primary chemotherapy does not influence prognosis of patients with Hodgkin lymphoma.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014 Sep 10;158(3):428-32. Epub 2013 Apr 10.

Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2013.022DOI Listing
September 2014

Interferon-alpha in chronic myeloid leukemia revisited: a long-term retrospective study in Central and Northern Moravia.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2013 Sep 27;157(3):248-56. Epub 2012 Nov 27.

Department of Hemato-Oncology, University Hospital Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2012.068DOI Listing
September 2013

A significant proportion of patients with chronic myeloid leukemia and suboptimal response according to European Leukemia Net criteria have excellent prognosis without treatment change.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2013 Jun 30;157(2):181-8. Epub 2011 Nov 30.

Department of Hemato-Oncology, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2011.059DOI Listing
June 2013

High serum carbohydrate antigen-125 (CA-125) level predicts poor outcome in patients with follicular lymphoma independently of the FLIPI score.

Int J Hematol 2012 Jul 26;96(1):58-64. Epub 2012 May 26.

Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacký University Olomouc, I. P. Pavlova 6, Olomouc, Czech Republic.

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http://dx.doi.org/10.1007/s12185-012-1102-1DOI Listing
July 2012

Comparison of new flu-bu12-tg conditioning with the standard bu-cy myeloablative regimen in patients undergoing allogeneic stem cell transplantation for acute myeloid leukemia.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2011 Dec;155(4):327-32

Department of Hemato-Oncology, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2011.040DOI Listing
December 2011

High baseline serum thymidine kinase 1 level predicts unfavorable outcome in patients with follicular lymphoma.

Leuk Lymphoma 2012 Jul 21;53(7):1306-10. Epub 2012 Feb 21.

Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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http://dx.doi.org/10.3109/10428194.2011.654339DOI Listing
July 2012

Imatinib trough plasma levels do not correlate with the response to therapy in patients with chronic myeloid leukemia in routine clinical setting.

Ann Hematol 2012 Jun 11;91(6):923-9. Epub 2012 Jan 11.

Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacký University Olomouc, University Hospital Olomouc, Czech Republic.

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http://dx.doi.org/10.1007/s00277-011-1394-xDOI Listing
June 2012

Operational cures after interferon-alpha in patients with chronic myeloid leukemia in Central and Northern Moravia.

J Interferon Cytokine Res 2012 May 22;32(5):230-4. Epub 2011 Dec 22.

Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University in Olomouc, Olomouc, Czech Republic.

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http://dx.doi.org/10.1089/jir.2011.0108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354581PMC
May 2012

Identification of e6a2 BCR-ABL fusion in a Philadelphia-positive CML with marked basophilia: implications for treatment strategy.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2011 Jun;155(2):187-90

Department of Hemato-Oncology, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2011.030DOI Listing
June 2011

Interactions of N-desmethyl imatinib, an active metabolite of imatinib, with P-glycoprotein in human leukemia cells.

Ann Hematol 2011 Jul 12;90(7):837-42. Epub 2011 Jan 12.

Department of Biology, Faculty of Medicine and Dentistry, Palacky University Olomouc, Hnevotinska 3, Olomouc, 77515, Czech Republic.

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http://dx.doi.org/10.1007/s00277-010-1142-7DOI Listing
July 2011

Flow injection analysis vs. ultra high performance liquid chromatography coupled with tandem mass spectrometry for determination of imatinib in human plasma.

Clin Chim Acta 2010 Dec 13;411(23-24):1957-62. Epub 2010 Aug 13.

Laboratory of Inherited Metabolic Disorders, University Hospital and Palacký University in Olomouc, I.P. Pavlova 6, CZ 775 20 Olomouc, Czech Republic.

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https://linkinghub.elsevier.com/retrieve/pii/S00098981100051
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http://dx.doi.org/10.1016/j.cca.2010.08.014DOI Listing
December 2010

Salivary neutrophils level as an indicator of bone marrow engraftment.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2009 Dec;153(4):263-9

Department of Oral and Maxillofacial Surgery, University Hospital, Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2009.051DOI Listing
December 2009

Saliva as a diagnostic medium.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2009 Jun;153(2):103-10

Department of Oral and Maxillofacial Surgery, University Hospital, Olomouc, 775 20, Czech Republic.

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http://dx.doi.org/10.5507/bp.2009.017DOI Listing
June 2009

Prevalence and spread of pseudomonas aeruginosa and Klebsiella pneumoniae strains in patients with hematological malignancies.

New Microbiol 2009 Jan;32(1):67-76

Department of Microbiology, Faculty of Medicine and Dentistry, Palacký University in Olomouc, Czech Republic.

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January 2009

Prolonged survival of patients with peripheral T-cell lymphoma after first-line intensive sequential chemotherapy with autologous stem cell transplantation.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2009 Mar;153(1):63-6

Department of Hemato-Oncology, University Hospital, Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2009.011DOI Listing
March 2009

Possible impact of MADCAM1 gene single nucleotide polymorphisms to the outcome of allogeneic hematopoietic stem cell transplantation.

Hum Immunol 2009 Jun 12;70(6):457-60. Epub 2009 Mar 12.

Laboratory of Immunogenomics and Proteomics, Department of Immunology, Palacky University and University Hospital, Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.humimm.2009.03.008DOI Listing
June 2009

Has the time come for induction and maintenance imatinib therapy in chronic myeloid leukemia?

Authors:
Edgar Faber

Leuk Res 2009 May 4;33(5):605-6. Epub 2008 Dec 4.

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http://dx.doi.org/10.1016/j.leukres.2008.10.021DOI Listing
May 2009

[Occurrence of AmpC-positive Klebsiella pneumoniae strains in patients with haematological malignancies].

Klin Mikrobiol Infekc Lek 2008 Oct;14(5):173-7

Institute of Microbiology Faculty of Medicine UP Olomouc, Olomouc, Czech Republic.

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October 2008

Successful childbirth in a patient with chronic myelogenous leukemia treated with imatinib mesylate during early pregnancy.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2008 Jun;152(1):121-3

Department of Hemato-Oncology, Teaching Hospital Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2008.019DOI Listing
June 2008

Sources and pathways of spread of vancomycin-resistant enterococci in hemato-oncological patients.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2006 Jul;150(1):117-20

Department of Microbiology, Faculty of Medicine, Palacky University, University Hospital Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2006.017DOI Listing
July 2006

Intermittent dosage of imatinib mesylate in CML patients with a history of significant hematologic toxicity after standard dosing.

Leuk Lymphoma 2006 Jun;47(6):1082-90

Department of Hemato-Oncology, University Hospital Olomouc and Faculty of Medicine, Palacky University in Olomouc, Olomouc, Czech Republic.

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http://dx.doi.org/10.1080/10428190600565057DOI Listing
June 2006