Publications by authors named "Eddy S Yang"

94Publications

Role of orbitofrontal cortex in incubation of oxycodone craving in male rats.

Addict Biol 2020 Jun 22:e12927. Epub 2020 Jun 22.

Department of Psychology, University of Maryland College Park, College Park, MD, USA.

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http://dx.doi.org/10.1111/adb.12927DOI Listing
June 2020

CHK1/2 Inhibitor Prexasertib Suppresses NOTCH Signaling and Enhances Cytotoxicity of Cisplatin and Radiation in Head and Neck Squamous Cell Carcinoma.

Mol Cancer Ther 2020 06 5;19(6):1279-1288. Epub 2020 May 5.

Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama.

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http://dx.doi.org/10.1158/1535-7163.MCT-19-0946DOI Listing
June 2020

Osteoporosis screening using computed tomography for men with prostate cancer: results of a prospective study.

Arch Osteoporos 2020 02 29;15(1):32. Epub 2020 Feb 29.

Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1007/s11657-020-0711-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402416PMC
February 2020

Combined Targeting of Mutant p53 and Jumonji Family Histone Demethylase Augments Therapeutic Efficacy of Radiation in H3K27M DIPG.

Int J Mol Sci 2020 Jan 13;21(2). Epub 2020 Jan 13.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA.

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http://dx.doi.org/10.3390/ijms21020490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7014308PMC
January 2020

Differential escape mechanisms in cetuximab-resistant head and neck cancer cells.

Biochem Biophys Res Commun 2019 09 13;517(1):36-42. Epub 2019 Jul 13.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL, 35249, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.06.159DOI Listing
September 2019

The BET inhibitor JQ1 attenuates double-strand break repair and sensitizes models of pancreatic ductal adenocarcinoma to PARP inhibitors.

EBioMedicine 2019 Jun 22;44:419-430. Epub 2019 May 22.

Department of Pharmacology and Toxicology, University of Alabama at Birmingham, 1670 University Blvd, Birmingham, AL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.05.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604668PMC
June 2019

Targeting DNA repair in precision medicine.

Adv Protein Chem Struct Biol 2019 5;115:135-155. Epub 2018 Dec 5.

Department of Radiation Oncology, University of Alabama-Birmingham School of Medicine, Birmingham, AL, United States; Hugh Kaul Precision Medicine Institute, University of Alabama-Birmingham School of Medicine, Birmingham, AL, United States. Electronic address:

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http://dx.doi.org/10.1016/bs.apcsb.2018.10.005DOI Listing
December 2019

Patient Demographics and Referral Patterns for [F-18]Fluciclovine-PET Imaging at a Tertiary Academic Medical Center.

J Am Coll Radiol 2019 Mar 14;16(3):315-320. Epub 2018 Nov 14.

Department of Radiology, University of Alabama at Birmingham, Birmingham, Alabama; Department of Urology, University of Alabama at Birmingham, Birmingham, Alabama.

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https://linkinghub.elsevier.com/retrieve/pii/S15461440183116
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http://dx.doi.org/10.1016/j.jacr.2018.09.026DOI Listing
March 2019

The Impact of DNA Repair Pathways in Cancer Biology and Therapy.

Cancers (Basel) 2017 Sep 19;9(9). Epub 2017 Sep 19.

Department of Radiation Oncology, UAB Comprehensive Cancer Center, Birmingham, AL 35249, USA.

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http://dx.doi.org/10.3390/cancers9090126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615341PMC
September 2017

Presurgical weight loss affects tumour traits and circulating biomarkers in men with prostate cancer.

Br J Cancer 2017 Oct 7;117(9):1303-1313. Epub 2017 Sep 7.

University of Alabama at Birmingham Comprehensive Cancer Center, Wallace Tumor Institute, 1824 6th Avenue South, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1038/bjc.2017.303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5672928PMC
October 2017

Subcutaneous adipose tissue characteristics and the risk of biochemical recurrence in men with high-risk prostate cancer.

Urol Oncol 2017 11 7;35(11):663.e15-663.e21. Epub 2017 Aug 7.

Department of Radiation Oncology, University of Alabama at Birmingham, Hazelrig-Salter Radiation Oncology Center, Birmingham, AL.

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http://dx.doi.org/10.1016/j.urolonc.2017.07.012DOI Listing
November 2017

A step towards predicting checkpoint inhibitor response in kidney cancer.

Lancet Oncol 2017 08 26;18(8):982-983. Epub 2017 Jul 26.

Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(17)30533-8DOI Listing
August 2017

Potential biomarkers for radiosensitivity in head and neck cancers.

Ann Transl Med 2016 Dec;4(24):524

Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Alabama, USA.

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http://dx.doi.org/10.21037/atm.2016.12.45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5233482PMC
December 2016

Combining Chk1/2 Inhibition with Cetuximab and Radiation Enhances and Cytotoxicity in Head and Neck Squamous Cell Carcinoma.

Mol Cancer Ther 2017 04 30;16(4):591-600. Epub 2017 Jan 30.

Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560482PMC
April 2017

Poly(ADP-ribose) polymerase activity and inhibition in cancer.

Semin Cell Dev Biol 2017 03 10;63:144-153. Epub 2017 Jan 10.

Department of Radiation Oncology, University of Alabama at Birmingham, 1700 6th Avenue South, 176F Hazelrig-Salter Radiation Oncology Center, Room 2232-N, Birmingham, AL 35249-6832, United States. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2017.01.007DOI Listing
March 2017

Let-7 Status Is Crucial for PARP1 Expression in HER2-Overexpressing Breast Tumors.

Mol Cancer Res 2017 03 28;15(3):340-347. Epub 2016 Dec 28.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0287-TDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334184PMC
March 2017

CT Measures of Bone Mineral Density and Muscle Mass Can Be Used to Predict Noncancer Death in Men with Prostate Cancer.

Radiology 2017 Feb 5;282(2):475-483. Epub 2016 Sep 5.

From the Department of Radiation Oncology (A.M.M., R.A.C., E.S.Y., J.B.F.), School of Public Health (T.A.S.), and School of Medicine (C.B.B., D.M.H.), Hazelrig-Salter Radiation Oncology Center, University of Alabama at Birmingham, 1700 6th Ave S, Birmingham, AL 35233; and Department of Radiation Oncology, Tufts University, Medford, Mass (D.L.M.).

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http://dx.doi.org/10.1148/radiol.2016160626DOI Listing
February 2017

DNA-Pk expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery.

Head Neck 2017 02 10;39(2):206-214. Epub 2016 Aug 10.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1002/hed.24562DOI Listing
February 2017

Notch Signaling Activation Is Associated with Patient Mortality and Increased FGF1-Mediated Invasion in Squamous Cell Carcinoma of the Oral Cavity.

Mol Cancer Res 2016 09 27;14(9):883-91. Epub 2016 Jun 27.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1158/1541-7786.MCR-16-0114DOI Listing
September 2016

Current and Emerging Clinical Applications of Multispectral Optoacoustic Tomography (MSOT) in Oncology.

Clin Cancer Res 2016 07 20;22(14):3432-9. Epub 2016 May 20.

Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046137PMC
http://dx.doi.org/10.1158/1078-0432.CCR-16-0573DOI Listing
July 2016

Pelvic Radiotherapy versus Radical Prostatectomy with Limited Lymph Node Sampling for High-Grade Prostate Adenocarcinoma.

Prostate Cancer 2016 9;2016:2674954. Epub 2016 Mar 9.

Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, AL 35249, USA.

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http://dx.doi.org/10.1155/2016/2674954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804089PMC
April 2016

Prostate Radiotherapy in the Era of Advanced Imaging and Precision Medicine.

Prostate Cancer 2016 16;2016:4897515. Epub 2016 Feb 16.

Department of Urology, University of Alabama at Birmingham, Birmingham, AL 35294, USA; Department of Radiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1155/2016/4897515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771898PMC
March 2016

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Authors:
Keith I Block Charlotte Gyllenhaal Leroy Lowe Amedeo Amedei A R M Ruhul Amin Amr Amin Katia Aquilano Jack Arbiser Alexandra Arreola Alla Arzumanyan S Salman Ashraf Asfar S Azmi Fabian Benencia Dipita Bhakta Alan Bilsland Anupam Bishayee Stacy W Blain Penny B Block Chandra S Boosani Thomas E Carey Amancio Carnero Marianeve Carotenuto Stephanie C Casey Mrinmay Chakrabarti Rupesh Chaturvedi Georgia Zhuo Chen Helen Chen Sophie Chen Yi Charlie Chen Beom K Choi Maria Rosa Ciriolo Helen M Coley Andrew R Collins Marisa Connell Sarah Crawford Colleen S Curran Charlotta Dabrosin Giovanna Damia Santanu Dasgupta Ralph J DeBerardinis William K Decker Punita Dhawan Anna Mae E Diehl Jin-Tang Dong Q Ping Dou Janice E Drew Eyad Elkord Bassel El-Rayes Mark A Feitelson Dean W Felsher Lynnette R Ferguson Carmela Fimognari Gary L Firestone Christian Frezza Hiromasa Fujii Mark M Fuster Daniele Generali Alexandros G Georgakilas Frank Gieseler Michael Gilbertson Michelle F Green Brendan Grue Gunjan Guha Dorota Halicka William G Helferich Petr Heneberg Patricia Hentosh Matthew D Hirschey Lorne J Hofseth Randall F Holcombe Kanya Honoki Hsue-Yin Hsu Gloria S Huang Lasse D Jensen Wen G Jiang Lee W Jones Phillip A Karpowicz W Nicol Keith Sid P Kerkar Gazala N Khan Mahin Khatami Young H Ko Omer Kucuk Rob J Kulathinal Nagi B Kumar Byoung S Kwon Anne Le Michael A Lea Ho-Young Lee Terry Lichtor Liang-Tzung Lin Jason W Locasale Bal L Lokeshwar Valter D Longo Costas A Lyssiotis Karen L MacKenzie Meenakshi Malhotra Maria Marino Maria L Martinez-Chantar Ander Matheu Christopher Maxwell Eoin McDonnell Alan K Meeker Mahya Mehrmohamadi Kapil Mehta Gregory A Michelotti Ramzi M Mohammad Sulma I Mohammed D James Morre Vinayak Muralidhar Irfana Muqbil Michael P Murphy Ganji Purnachandra Nagaraju Rita Nahta Elena Niccolai Somaira Nowsheen Carolina Panis Francesco Pantano Virginia R Parslow Graham Pawelec Peter L Pedersen Brad Poore Deepak Poudyal Satya Prakash Mark Prince Lizzia Raffaghello Jeffrey C Rathmell W Kimryn Rathmell Swapan K Ray Jörg Reichrath Sarallah Rezazadeh Domenico Ribatti Luigi Ricciardiello R Brooks Robey Francis Rodier H P Vasantha Rupasinghe Gian Luigi Russo Elizabeth P Ryan Abbas K Samadi Isidro Sanchez-Garcia Andrew J Sanders Daniele Santini Malancha Sarkar Tetsuro Sasada Neeraj K Saxena Rodney E Shackelford H M C Shantha Kumara Dipali Sharma Dong M Shin David Sidransky Markus David Siegelin Emanuela Signori Neetu Singh Sharanya Sivanand Daniel Sliva Carl Smythe Carmela Spagnuolo Diana M Stafforini John Stagg Pochi R Subbarayan Tabetha Sundin Wamidh H Talib Sarah K Thompson Phuoc T Tran Hendrik Ungefroren Matthew G Vander Heiden Vasundara Venkateswaran Dass S Vinay Panagiotis J Vlachostergios Zongwei Wang Kathryn E Wellen Richard L Whelan Eddy S Yang Huanjie Yang Xujuan Yang Paul Yaswen Clement Yedjou Xin Yin Jiyue Zhu Massimo Zollo

Semin Cancer Biol 2015 Dec;35 Suppl:S276-S304

Centro di Ingegneria Genetica e Biotecnologia Avanzate, Naples, Italy; Department of Molecular Medicine and Medical Biotechnology, Federico II, Via Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1016/j.semcancer.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819002PMC
December 2015

Enhancement of Cetuximab-Induced Radiosensitization by JAK-1 Inhibition.

BMC Cancer 2015 Oct 12;15:673. Epub 2015 Oct 12.

The University of Alabama at Birmingham, Department of Radiation Oncology, Hazelrig-Salter Radiation Oncology Center, Suite 2262, 1700 6th Avenue South, Birmingham, AL, 35249, UK.

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http://dx.doi.org/10.1186/s12885-015-1679-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603644PMC
October 2015

Effect of African-American Race on Tumor Recurrence After Radical Cystectomy for Urothelial Carcinoma of the Bladder.

Clin Genitourin Cancer 2015 Oct 6;13(5):469-75. Epub 2015 Mar 6.

Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, AL; Division of Hematology Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, AL. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2015.02.010DOI Listing
October 2015

PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers.

Breast Cancer Res Treat 2015 Apr 2;150(3):569-79. Epub 2015 Apr 2.

Department of Radiation Oncology, University of Alabama at Birmingham, 1700 6th Avenue South, 176F HSROC Rm 2232 N, Birmingham, AL, USA.

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http://dx.doi.org/10.1007/s10549-015-3359-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396624PMC
April 2015

An ex vivo assay of XRT-induced Rad51 foci formation predicts response to PARP-inhibition in ovarian cancer.

Gynecol Oncol 2014 Aug 15;134(2):331-7. Epub 2014 May 15.

Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2014.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221419PMC
August 2014

Activity of CEP-9722, a poly (ADP-ribose) polymerase inhibitor, in urothelial carcinoma correlates inversely with homologous recombination repair response to DNA damage.

Anticancer Drugs 2014 Sep;25(8):878-86

Departments of aUrology bImmunology, Baylor College of Medicine, Houston, Texas cDepartment of Medicine, Division of Hematology-Oncology dDepartment of Radiation Oncology, University of Alabama, Birmingham (UAB) Comprehensive Cancer Center, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1097/CAD.0000000000000114DOI Listing
September 2014

Beyond DNA Repair: Additional Functions of PARP-1 in Cancer.

Front Oncol 2013 Nov 27;3:290. Epub 2013 Nov 27.

Department of Radiation Oncology, School of Medicine, The University of Alabama at Birmingham , Birmingham, AL , USA ; Department of Cell, Developmental, and Integrative Biology, School of Medicine, The University of Alabama at Birmingham , Birmingham, AL , USA ; Department of Pharmacology and Toxicology, School of Medicine, The University of Alabama at Birmingham , Birmingham, AL , USA.

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http://dx.doi.org/10.3389/fonc.2013.00290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3841914PMC
November 2013

Discussion of PARP inhibitors in cancer therapy.

Pharm Pat Anal 2013 Nov;2(6):755-66

Department of Radiation Oncology, Comprehensive Cancer Center, School of Medicine, University of Alabama at Birmingham, 1700 6th Avenue South, AL 35294-6832, USA.

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http://dx.doi.org/10.4155/ppa.13.53DOI Listing
November 2013

PARP-1: Friend or Foe of DNA Damage and Repair in Tumorigenesis?

Cancers (Basel) 2013 Jul 26;5(3):943-58. Epub 2013 Jul 26.

Department of Radiation Oncology Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, 176F HSROC Suite 2232B, 1700 6th Avenue South, Birmingham, AL 35249, USA.

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http://dx.doi.org/10.3390/cancers5030943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795373PMC
July 2013

Assaying DNA damage in hippocampal neurons using the comet assay.

J Vis Exp 2012 Dec 19(70):e50049. Epub 2012 Dec 19.

Department of Radiation Oncology, University of Alabama-Birmingham.

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http://dx.doi.org/10.3791/50049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576424PMC
December 2012

Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer.

Clin Cancer Res 2013 Jan 12;19(1):170-82. Epub 2012 Nov 12.

Departments of Obstetrics and Gynecology, Radiation Oncology, and Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-1045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3537868PMC
January 2013

Synthetic lethal interactions between EGFR and PARP inhibition in human triple negative breast cancer cells.

PLoS One 2012 11;7(10):e46614. Epub 2012 Oct 11.

Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046614PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469581PMC
April 2013

HER2 overexpression renders human breast cancers sensitive to PARP inhibition independently of any defect in homologous recombination DNA repair.

Cancer Res 2012 Sep;72(18):4796-806

Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-1287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458582PMC
September 2012

Hypofractionated Prostate Radiotherapy with or without Conventionally Fractionated Nodal Irradiation: Clinical Toxicity Observations and Retrospective Daily Dosimetry.

Prostate Cancer 2012 28;2012:546794. Epub 2012 Jun 28.

Department of Radiation Oncology, Hazelrig-Salter Radiation Oncology Center, University of Alabama at Birmingham, 1700 6th Avenue South Birmingham, Birmingham, AL 35249, USA.

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http://www.hindawi.com/journals/pc/2012/546794/
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http://dx.doi.org/10.1155/2012/546794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394386PMC
September 2012

Targeting BRCA1 localization to augment breast tumor sensitivity to poly(ADP-Ribose) polymerase inhibition.

Cancer Res 2012 Nov 7;72(21):5547-55. Epub 2012 Sep 7.

Departments of Radiation Oncology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771348PMC
November 2012

Epigenetic inactivation of DNA repair in breast cancer.

Cancer Lett 2014 Jan 23;342(2):213-22. Epub 2012 May 23.

Department of Radiation Oncology, Hazelrig-Salter Radiation Oncology Center, University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, AL 35294, USA.

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http://dx.doi.org/10.1016/j.canlet.2012.05.015DOI Listing
January 2014

Kinomic profiling approach identifies Trk as a novel radiation modulator.

Radiother Oncol 2012 Jun 5;103(3):380-7. Epub 2012 May 5.

Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL 35249-6832, USA.

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http://dx.doi.org/10.1016/j.radonc.2012.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368103PMC
June 2012

Emerging roles of glycogen synthase kinase 3 in the treatment of brain tumors.

Front Mol Neurosci 2011 25;4:47. Epub 2011 Nov 25.

Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama-Birmingham School of Medicine Birmingham, AL, USA.

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http://journal.frontiersin.org/article/10.3389/fnmol.2011.00
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http://dx.doi.org/10.3389/fnmol.2011.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223722PMC
October 2012

Cetuximab augments cytotoxicity with poly (adp-ribose) polymerase inhibition in head and neck cancer.

PLoS One 2011 30;6(8):e24148. Epub 2011 Aug 30.

Department of Radiation Oncology, Comprehensive Cancer Center, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024148PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166164PMC
December 2011

p53-dependent BRCA1 nuclear export controls cellular susceptibility to DNA damage.

Cancer Res 2011 Aug 8;71(16):5546-57. Epub 2011 Jul 8.

Departments of Radiation Oncology and Cancer Biology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-5671, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-3423DOI Listing
August 2011

Treatment of small cell lung cancer with TRA-8 in combination with cisplatin and radiation.

Radiother Oncol 2011 Oct 30;101(1):183-9. Epub 2011 Jun 30.

Department of Radiation Oncology, The University of Alabama, Birmingham, AL 35249, USA.

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http://dx.doi.org/10.1016/j.radonc.2011.05.083DOI Listing
October 2011

The poly(ADP-Ribose) polymerase inhibitor ABT-888 reduces radiation-induced nuclear EGFR and augments head and neck tumor response to radiotherapy.

Radiother Oncol 2011 Jun 28;99(3):331-8. Epub 2011 Jun 28.

Department of Radiation Oncology, University of Alabama at Birmingham School of Medicine, USA.

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http://dx.doi.org/10.1016/j.radonc.2011.05.084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157293PMC
June 2011

Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma.

Radiother Oncol 2011 Jun 23;99(3):339-43. Epub 2011 Jun 23.

Department of Radiation Oncology, The University of Alabama at Birmingham, USA.

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http://dx.doi.org/10.1016/j.radonc.2011.05.070DOI Listing
June 2011

Glycogen synthase kinase 3beta inhibition enhances repair of DNA double-strand breaks in irradiated hippocampal neurons.

Neuro Oncol 2011 May 11;13(5):459-70. Epub 2011 Mar 11.

Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN 37232-5671, USA.

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/nor016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3093336PMC
May 2011

DNA damage-induced cytotoxicity is dissociated from BRCA1's DNA repair function but is dependent on its cytosolic accumulation.

Cancer Res 2010 Aug 14;70(15):6258-67. Epub 2010 Jul 14.

Departments of Radiation Oncology and Cancer Biology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232-5671, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-4713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912952PMC
August 2010

BRCA1 16 years later: DNA damage-induced BRCA1 shuttling.

Authors:
Eddy S Yang Fen Xia

FEBS J 2010 Aug 1;277(15):3079-85. Epub 2010 Jul 1.

Department of Radiation Oncology, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232-5671, USA.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07734.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158790PMC
August 2010

Reduction of dose delivered to organs at risk in prostate cancer patients via image-guided radiation therapy.

Int J Radiat Oncol Biol Phys 2010 Mar 11;76(3):924-34. Epub 2009 Dec 11.

Department of Radiation Oncology, Vanderbilt University School of Medicine, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee 37232-5671, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2009.06.068DOI Listing
March 2010

Refractory lympho-epithelial carcinoma of the nasopharynx: a case report illustrating a protracted clinical course.

Head Neck Oncol 2009 Jun 15;1:18. Epub 2009 Jun 15.

Department of Radiation Oncology, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1186/1758-3284-1-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704192PMC
June 2009

Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice.

J Clin Invest 2009 May;119(5):1124-35

Department of Radiation Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673855PMC
http://dx.doi.org/10.1172/jci34051DOI Listing
May 2009

Erlotinib attenuates homologous recombinational repair of chromosomal breaks in human breast cancer cells.

Cancer Res 2008 Nov;68(22):9141-6

Department of Radiation Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586988PMC
November 2008

Evolution of clinical trials in head and neck cancer.

Crit Rev Oncol Hematol 2009 Jul 7;71(1):29-42. Epub 2008 Nov 7.

Department of Radiation Oncology, Vanderbilt University Medical Center, Nashville, TN 37232-5671, USA.

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http://dx.doi.org/10.1016/j.critrevonc.2008.09.015DOI Listing
July 2009

The role of mTOR inhibition in augmenting radiation induced autophagy.

Technol Cancer Res Treat 2007 Oct;6(5):443-7

Department of Radiation Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA.

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http://tct.sagepub.com/content/6/5/443.full.pdf
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http://dx.doi.org/10.1177/153303460700600510DOI Listing
October 2007

Autophagy signaling in cancer and its potential as novel target to improve anticancer therapy.

Drug Resist Updat 2007 Aug-Oct;10(4-5):135-43. Epub 2007 Jul 12.

Department of Radiation Oncology, Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, 1301 22nd Avenue South, B-902 The Vanderbilt Clinic, Nashville, TN 37232-5671, United States.

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http://dx.doi.org/10.1016/j.drup.2007.05.001DOI Listing
January 2008

Deregulation of the Rho GTPase, Rac1, suppresses cyclin-dependent kinase inhibitor p21(CIP1) levels in androgen-independent human prostate cancer cells.

Oncogene 2004 Jul;23(32):5513-22

Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, 1600 NW 10th Avenue, Miami, FL 33136, USA.

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http://dx.doi.org/10.1038/sj.onc.1207708DOI Listing
July 2004

Vitamin D inhibits G1 to S progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm.

J Biol Chem 2003 Nov 3;278(47):46862-8. Epub 2003 Sep 3.

Department of Molecular and Cellular Pharmacology, University of Miami School of Medicine, Miami, FL 33136, USA.

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http://dx.doi.org/10.1074/jbc.M306340200DOI Listing
November 2003

Vitamin D-mediated growth inhibition of an androgen-ablated LNCaP cell line model of human prostate cancer.

Mol Cell Endocrinol 2002 Jan;186(1):69-79

Department of Molecular and Cellular Pharmacology (R-189), University of Miami School of Medicine, PO Box 016189 (R-189), Miami, FL 33136, USA.

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http://dx.doi.org/10.1016/s0303-7207(01)00671-2DOI Listing
January 2002