Ed Reznik

Ed Reznik

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Ed Reznik

Ed Reznik

Publications by authors named "Ed Reznik"

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Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1.

Cell Metab 2019 Sep 24. Epub 2019 Sep 24.

Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15504131193049
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http://dx.doi.org/10.1016/j.cmet.2019.08.024DOI Listing
September 2019

Metabolomics informs common patterns of molecular dysfunction across histologies of renal cell carcinoma.

Urol Oncol 2019 May 30. Epub 2019 May 30.

Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2019.04.028DOI Listing
May 2019

Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma.

Proc Natl Acad Sci U S A 2018 07 11;115(27):E6274-E6282. Epub 2018 Jun 11.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115.

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http://dx.doi.org/10.1073/pnas.1710849115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142242PMC
July 2018

A Landscape of Metabolic Variation across Tumor Types.

Cell Syst 2018 Mar 27;6(3):301-313.e3. Epub 2018 Jan 27.

cBio Center, Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2017.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876114PMC
March 2018

Mitochondrial respiratory gene expression is suppressed in many cancers.

Elife 2017 01 18;6. Epub 2017 Jan 18.

Department of Cell Biology, Harvard Medical School, Boston, United States.

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http://dx.doi.org/10.7554/eLife.21592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243113PMC
January 2017

Mapping the landscape of metabolic goals of a cell.

Genome Biol 2016 05 23;17(1):109. Epub 2016 May 23.

Department of Biomedical Engineering, Boston University, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1186/s13059-016-0968-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878026PMC
May 2016

Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.

Cell Rep 2016 Mar 3;14(10):2476-89. Epub 2016 Mar 3.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794376PMC
March 2016

Mitochondrial DNA copy number variation across human cancers.

Elife 2016 Feb 22;5. Epub 2016 Feb 22.

Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, United States.

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http://dx.doi.org/10.7554/eLife.10769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775221PMC
February 2016

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

Authors:
W Marston Linehan Paul T Spellman Christopher J Ricketts Chad J Creighton Suzanne S Fei Caleb Davis David A Wheeler Bradley A Murray Laura Schmidt Cathy D Vocke Myron Peto Abu Amar M Al Mamun Eve Shinbrot Anurag Sethi Samira Brooks W Kimryn Rathmell Angela N Brooks Katherine A Hoadley A Gordon Robertson Denise Brooks Reanne Bowlby Sara Sadeghi Hui Shen Daniel J Weisenberger Moiz Bootwalla Stephen B Baylin Peter W Laird Andrew D Cherniack Gordon Saksena Scott Haake Jun Li Han Liang Yiling Lu Gordon B Mills Rehan Akbani Mark D M Leiserson Benjamin J Raphael Pavana Anur Donald Bottaro Laurence Albiges Nandita Barnabas Toni K Choueiri Bogdan Czerniak Andrew K Godwin A Ari Hakimi Thai H Ho James Hsieh Michael Ittmann William Y Kim Bhavani Krishnan Maria J Merino Kenna R Mills Shaw Victor E Reuter Ed Reznik Carl S Shelley Brian Shuch Sabina Signoretti Ramaprasad Srinivasan Pheroze Tamboli George Thomas Satish Tickoo Kenneth Burnett Daniel Crain Johanna Gardner Kevin Lau David Mallery Scott Morris Joseph D Paulauskis Robert J Penny Candace Shelton W Troy Shelton Mark Sherman Eric Thompson Peggy Yena Melissa T Avedon Jay Bowen Julie M Gastier-Foster Mark Gerken Kristen M Leraas Tara M Lichtenberg Nilsa C Ramirez Tracie Santos Lisa Wise Erik Zmuda John A Demchok Ina Felau Carolyn M Hutter Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean C Zenklusen Jiashan Zhang Brenda Ayala Julien Baboud Sudha Chudamani Jia Liu Laxmi Lolla Rashi Naresh Todd Pihl Qiang Sun Yunhu Wan Ye Wu Adrian Ally Miruna Balasundaram Saianand Balu Rameen Beroukhim Tom Bodenheimer Christian Buhay Yaron S N Butterfield Rebecca Carlsen Scott L Carter Hsu Chao Eric Chuah Amanda Clarke Kyle R Covington Mahmoud Dahdouli Ninad Dewal Noreen Dhalla Harsha V Doddapaneni Jennifer A Drummond Stacey B Gabriel Richard A Gibbs Ranabir Guin Walker Hale Alicia Hawes D Neil Hayes Robert A Holt Alan P Hoyle Stuart R Jefferys Steven J M Jones Corbin D Jones Divya Kalra Christie Kovar Lora Lewis Jie Li Yussanne Ma Marco A Marra Michael Mayo Shaowu Meng Matthew Meyerson Piotr A Mieczkowski Richard A Moore Donna Morton Lisle E Mose Andrew J Mungall Donna Muzny Joel S Parker Charles M Perou Jeffrey Roach Jacqueline E Schein Steven E Schumacher Yan Shi Janae V Simons Payal Sipahimalani Tara Skelly Matthew G Soloway Carrie Sougnez Angela Tam Donghui Tan Nina Thiessen Umadevi Veluvolu Min Wang Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Jane Zhou Jason Bedford Fengju Chen Yao Fu Mark Gerstein David Haussler Katayoon Kasaian Phillip Lai Shiyun Ling Amie Radenbaugh David Van Den Berg John N Weinstein Jingchun Zhu Monique Albert Iakovina Alexopoulou Jeremiah J Andersen J Todd Auman John Bartlett Sheldon Bastacky Julie Bergsten Michael L Blute Lori Boice Roni J Bollag Jeff Boyd Erik Castle Ying-Bei Chen John C Cheville Erin Curley Benjamin Davies April DeVolk Rajiv Dhir Laura Dike John Eckman Jay Engel Jodi Harr Ronald Hrebinko Mei Huang Lori Huelsenbeck-Dill Mary Iacocca Bruce Jacobs Michael Lobis Jodi K Maranchie Scott McMeekin Jerome Myers Joel Nelson Jeremy Parfitt Anil Parwani Nicholas Petrelli Brenda Rabeno Somak Roy Andrew L Salner Joel Slaton Melissa Stanton R Houston Thompson Leigh Thorne Kelinda Tucker Paul M Weinberger Cynthia Winemiller Leigh Anne Zach Rosemary Zuna

MutationAligner: a resource of recurrent mutation hotspots in protein domains in cancer.

Nucleic Acids Res 2016 Jan 20;44(D1):D986-91. Epub 2015 Nov 20.

Cancer Research UK, Cambridge Institute, University of Cambridge, Cambridge, CB2 0RE, UK

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http://dx.doi.org/10.1093/nar/gkv1132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702822PMC
January 2016

Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.

Cell Syst 2015 Sep 23;1(3):197-209. Epub 2015 Sep 23.

Computational Biology Program, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2015.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982675PMC
September 2015

Graph Curvature for Differentiating Cancer Networks.

Sci Rep 2015 Jul 14;5:12323. Epub 2015 Jul 14.

Departments of Computer Science and Applied Mathematics/Statistics, Stony Brook University, Stony Brook, NY 11794.

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http://dx.doi.org/10.1038/srep12323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500997PMC
July 2015

Extensive decoupling of metabolic genes in cancer.

PLoS Comput Biol 2015 May 11;11(5):e1004176. Epub 2015 May 11.

Computational Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.

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https://dx.plos.org/10.1371/journal.pcbi.1004176
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http://dx.doi.org/10.1371/journal.pcbi.1004176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427321PMC
May 2015

Flux imbalance analysis and the sensitivity of cellular growth to changes in metabolite pools.

PLoS Comput Biol 2013 29;9(8):e1003195. Epub 2013 Aug 29.

Department of Biomedical Engineering, Boston University, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757068PMC
February 2014

Pathway thermodynamics highlights kinetic obstacles in central metabolism.

PLoS Comput Biol 2014 Feb 20;10(2):e1003483. Epub 2014 Feb 20.

Department of Plant Sciences, The Weizmann Institute of Science, Rehovot, Israel.

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http://dx.doi.org/10.1371/journal.pcbi.1003483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930492PMC
February 2014

The average enzyme principle.

FEBS Lett 2013 Sep 23;587(17):2891-4. Epub 2013 Jul 23.

Computational Biology Center, Sloan-Kettering Institute for Cancer Research, New York, NY, USA.

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http://dx.doi.org/10.1016/j.febslet.2013.07.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983706PMC
September 2013

The stubborn roots of metabolic cycles.

J R Soc Interface 2013 Jun 3;10(83):20130087. Epub 2013 Apr 3.

Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.

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http://dx.doi.org/10.1098/rsif.2013.0087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645417PMC
June 2013

Temporal expression-based analysis of metabolism.

PLoS Comput Biol 2012 29;8(11):e1002781. Epub 2012 Nov 29.

Program in Bioinformatics, Boston University, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1002781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510039PMC
April 2013

Invariance and optimality in the regulation of an enzyme.

Biol Direct 2013 Mar 22;8. Epub 2013 Mar 22.

Department of Biomedical Engineering, Boston University, 44 Cummington Mall, Boston, MA 02215, USA.

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http://dx.doi.org/10.1186/1745-6150-8-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3665469PMC
March 2013

The dynamics of hybrid metabolic-genetic oscillators.

Chaos 2013 Mar;23(1):013132

Department of Biomedical Engineering, Boston University, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1063/1.4793573DOI Listing
March 2013

On the stability of metabolic cycles.

J Theor Biol 2010 Oct 29;266(4):536-49. Epub 2010 Jul 29.

Bioinformatics Program, 24 Cummington St, Boston, MA, United States. addresses:

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http://dx.doi.org/10.1016/j.jtbi.2010.07.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038548PMC
October 2010