Eckhard Wolf

Eckhard Wolf

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Eckhard Wolf

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In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.

Biochim Biophys Acta Mol Basis Dis 2020 Mar 23;1866(3):165622. Epub 2019 Nov 23.

Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; radiz - Rare Disease Initiative Zurich, Clinical Research Priority Program for Rare Diseases, University of Zurich, Zurich, Switzerland; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2019.165622DOI Listing
March 2020

Cellular and Molecular Probing of Intact Human Organs.

Cell 2020 Feb 13;180(4):796-812.e19. Epub 2020 Feb 13.

Insititute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Zentrum München, 85764 Neuherberg, Germany; Institute for Stroke and Dementia Research (ISD), University Hospital, Ludwig Maximilian University of Munich (LMU), 81377 Munich, Germany; Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.01.030DOI Listing
February 2020

Porcine models for studying complications and organ crosstalk in diabetes mellitus.

Cell Tissue Res 2020 Jan 13. Epub 2020 Jan 13.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center, LMU Munich, Feodor-Lynen-Strasse 25, D-81377, Munich, Germany.

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http://dx.doi.org/10.1007/s00441-019-03158-9DOI Listing
January 2020

Comparative aspects of early lineage specification events in mammalian embryos - insights from reverse genetics studies.

Cell Cycle 2018 21;17(14):1688-1695. Epub 2018 Aug 21.

a Molecular Animal Breeding and Biotechnology, Gene Center , LMU Munich , Munich , Germany.

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http://dx.doi.org/10.1080/15384101.2018.1496747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6133330PMC
November 2019

Sex-specific programming effects of parental obesity in pre-implantation embryonic development.

Int J Obes (Lond) 2019 Nov 27. Epub 2019 Nov 27.

Institute of Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, Feodor-Lynen-Strasse 25, 81377, Munich, Germany.

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http://dx.doi.org/10.1038/s41366-019-0494-xDOI Listing
November 2019

Animal models of arrhythmia: classic electrophysiology to genetically modified large animals.

Nat Rev Cardiol 2019 08;16(8):457-475

Department of Medicine I, University Hospital Munich, Campus Grosshadern, Ludwig-Maximilians University Munich (LMU), Munich, Germany.

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http://www.nature.com/articles/s41569-019-0179-0
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http://dx.doi.org/10.1038/s41569-019-0179-0DOI Listing
August 2019

Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.

Mol Metab 2019 08 4;26:30-44. Epub 2019 Jun 4.

Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, 81377 Munich, Germany; Center for Innovative Medical Models (CiMM), LMU Munich, 85764 Oberschleißheim, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667734PMC
August 2019

Genetically modified pigs as donors of cells, tissues, and organs for xenotransplantation.

Anim Front 2019 Jul 25;9(3):13-20. Epub 2019 Jun 25.

Walter Brendel Center for Experimental Medicine, LMU Munich, Germany.

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http://dx.doi.org/10.1093/af/vfz014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6951927PMC
July 2019

Targeting αGal epitopes for multi-species embryo immunosurgery.

Reprod Fertil Dev 2019 Apr;31(4):820-826

Chair for Molecular Animal Breeding and Biotechnology, Centre for Innovative Medical Models (CiMM), LMU Munich, Hacker strasse 27, 85764 Oberschleissheim, Germany.

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http://www.publish.csiro.au/?paper=RD18120
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http://dx.doi.org/10.1071/RD18120DOI Listing
April 2019

Recent progress in porcine islet isolation, culture and engraftment strategies for xenotransplantation.

Curr Opin Organ Transplant 2018 12;23(6):633-641

Chair for Molecular Animal Breeding and Biotechnology, Gene Center.

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http://dx.doi.org/10.1097/MOT.0000000000000579DOI Listing
December 2018

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Behav Brain Res 2018 10 29;352:187-196. Epub 2017 Sep 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD), Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; Chair of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Alte Akademie 8, 85354 Freising, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2017.09.048DOI Listing
October 2018

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs.

Mol Metab 2018 10 28;16:180-190. Epub 2018 Jun 28.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany; Center for Innovative Medical Models (CiMM), Department of Veterinary Sciences, LMU Munich, Hackerstr. 27, 85764, Oberschleißheim, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstr. 1, 85764, Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.

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http://dx.doi.org/10.1016/j.molmet.2018.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157610PMC
October 2018

Will Genetic Engineering Carry Xenotransplantation of Pig Islets to the Clinic?

Curr Diab Rep 2018 09 18;18(11):103. Epub 2018 Sep 18.

Gene Center, and Center for Innovative Medical Models (CiMM), LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.

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http://dx.doi.org/10.1007/s11892-018-1074-5DOI Listing
September 2018

Early weaning completely eliminates porcine cytomegalovirus from a newly established pig donor facility for xenotransplantation.

Xenotransplantation 2018 07;25(4):e12449

Center for Innovative Medical Models (CiMM), Institute for Molecular Animal Breeding and Biotechnology, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1111/xen.12449DOI Listing
July 2018

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.

Mol Metab 2018 05 15;11:113-128. Epub 2018 Mar 15.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Feodor-Lynen-Str. 25, 81377 Munich, Germany; Center for Innovative Medical Models (CiMM), Department of Veterinary Sciences, LMU Munich, Hackerstr. 27, 85764 Oberschleißheim, Germany; Meiji University International Institute for Bio-Resource Research, 1-1-1 Higashimita, Tama, Kawasaki, 214-8571, Japan; German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, 81377 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2018.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001387PMC
May 2018

CD1a-Expressing Monocytes as Mediators of Inflammation in Ulcerative Colitis.

Inflamm Bowel Dis 2018 May 17. Epub 2018 May 17.

Department of General- Visceral-, Vascular- and Transplantation Surgery, Hospital of the LMU, Munich, Germany.

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http://dx.doi.org/10.1093/ibd/izy073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176881PMC
May 2018

Animal models of obesity and diabetes mellitus.

Nat Rev Endocrinol 2018 03 19;14(3):140-162. Epub 2018 Jan 19.

Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstr. 1, D-85764 Neuherberg, Germany.

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http://dx.doi.org/10.1038/nrendo.2017.161DOI Listing
March 2018

OCT4/POU5F1 is required for NANOG expression in bovine blastocysts.

Proc Natl Acad Sci U S A 2018 03 26;115(11):2770-2775. Epub 2018 Feb 26.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, 81377 Munich, Germany;

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http://dx.doi.org/10.1073/pnas.1718833115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856541PMC
March 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Nat Commun 2018 01 18;9(1):288. Epub 2018 Jan 18.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

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http://dx.doi.org/10.1038/s41467-017-01995-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773596PMC
January 2018

Design and validation of a disease network of inflammatory processes in the NSG-UC mouse model.

J Transl Med 2017 12 28;15(1):265. Epub 2017 Dec 28.

Department of General- Visceral-, and Transplantation Surgery, Hospital of the University of Munich, Nussbaumstr. 20, 80336, Munich, Germany.

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http://dx.doi.org/10.1186/s12967-017-1368-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745765PMC
December 2017

Effect of metabolic status on conceptus-maternal interactions on day 19 in dairy cattle: II. Effects on the endometrial transcriptome.

Biol Reprod 2017 Sep;97(3):413-425

Division of Reproduction and Early Development, Faculty of Medicine and Health Sciences, University of Leeds, UK.

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http://dx.doi.org/10.1093/biolre/iox095DOI Listing
September 2017

Retinopathy with central oedema in an INS transgenic pig model of long-term diabetes.

Diabetologia 2017 08 8;60(8):1541-1549. Epub 2017 May 8.

Experimental Ophthalmology, Philipps University of Marburg, Baldingerstrasse, D-35033, Marburg, Germany.

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http://link.springer.com/10.1007/s00125-017-4290-7
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http://dx.doi.org/10.1007/s00125-017-4290-7DOI Listing
August 2017

The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.

Mol Metab 2017 08 13;6(8):931-940. Epub 2017 Jun 13.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, and Center for Innovative Medical Models (CiMM), LMU Munich, Feodor-Lynen-Str. 25, D-81377 Munich, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstr. 1, D-85764 Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, D-81377 Munich, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778173031
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http://dx.doi.org/10.1016/j.molmet.2017.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518720PMC
August 2017

Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice.

Biochim Biophys Acta Mol Basis Dis 2017 06 21;1863(6):1605-1614. Epub 2017 Feb 21.

Research Center, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-Universität München, Lindwurmstrasse 4, 80337 Munich, Germany; Experimental Pediatrics and Metabolism, Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital, Heinrich Heine University Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbadis.2017.02.021DOI Listing
June 2017

Vessel Network Architecture of Adult Human Islets Promotes Distinct Cell-Cell Interactions In Situ and Is Altered After Transplantation.

Endocrinology 2017 05;158(5):1373-1385

Paul Langerhans Institute Dresden of Helmholtz Zentrum München at the University Clinic Carl Gustav Carus of Technische Universität Dresden, Helmholtz Zentrum München, 85764 München-Neuherberg, Germany.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2016-1184DOI Listing
May 2017

Abstracts of the 52nd Workshop for Pediatric Research : Frankfurt, Germany. 27-28 October 2016.

Authors:
Rhea van den Bruck Patrick P Weil Thomas Ziegenhals Philipp Schreiner Stefan Juranek Daniel Gödde Silvia Vogel Frauke Schuster Valerie Orth Johannes Dörner Daniel Pembaur Meike Röper Stefan Störkel Hubert Zirngibl Stefan Wirth Andreas C W Jenke Jan Postberg Nikolas Boy Jana Heringer Gisela Haege Esther M Glahn Georg F Hoffmann Sven F Garbade Peter Burgard Stefan Kölker Cho-Ming Chao Faady Yahya Alena Moiseenko Amit Shrestha Negah Ahmadvand Jennifer Quantius Jochen Wilhelm Elie El-Agha Klaus-Peter Zimmer Saverio Bellusci Christian Staufner Stefan Kölker Holger Prokisch Georg F Hoffmann Stephan Seeliger Matthias Müller Andreas Hippe Henrik Steinkraus Roland Wauer Burkhard Lachmann Sigrun R Hofmann Christian M Hedrich Jakob Zierk Farhad Arzideh Rainer Haeckel Wolfgang Rascher Manfred Rauh Markus Metzler Sebastian Thieme Joanna Bandoła Cornelia Richter Martin Ryser Arshad Jamal Michelle P Ashton Malte von Bonin Matthias Kuhn Christian M Hedrich Ezio Bonifacio Reinhard Berner Sebastian Brenner Johanna Hammersen Cristina Has Nora Naumann-Bartsch Daniel Stachel Dimitra Kiritsi Stephan Söder Mathilde Tardieu Markus Metzler Leena Bruckner-Tuderman Holm Schneider F Bohne D Langer R Cencic T Eggermann U Zechner J Pelletier F Zepp T Enklaar D Prawitt Martin Pech Markus Weckmann Femke-Anouska Heinsen Andre Franke Christine Happle Anna-Maria Dittrich Gesine Hansen Oliver Fuchs Erika von Mutius Brian G Oliver Matthias V Kopp Claudia Paret Alexandra Russo Johanna Theruvath Bettina Keller Khalifa El Malki Nadine Lehmann Arthur Wingerter Marie A Neu Gerhold-Ay Aslihan Wolfgang Wagner Clemens Sommer Torsten Pietsch Larissa Seidmann Jörg Faber Felix Schreiner Merle Ackermann Michael Michalik Eva Rother Andras Bilkei-Gorzo Ildiko Racz Laura Bindila Beat Lutz Jörg Dötsch Andreas Zimmer Joachim Woelfle Hendrik S Fischer Tim L Ullrich Christoph Bührer Christoph Czernik Gerd Schmalisch Robert Stein Sigrun R Hofmann Judith Hagenbuchner Ursula Kiechl-Kohlendorfer Petra Obexer Michael J Ausserlechner Niki T Loges Adrien Tobias Frommer Julia Wallmeier Heymut Omran Soner Öner-Sieben Martina Gimpfl Jan Rozman Martin Irmler Johannes Beckers Martin Hrabe De Angelis Adelbert Roscher Eckhard Wolf Regina Ensenauer Karolina Nemes Michael Frühwald Martin Hasselblatt Reiner Siebert Uwe Kordes Marcel Kool Haicui Wang Holly Hardy Osama Refai Katy E S Barwick Holly H Zimmerman Joachim Weis Emma L Baple Andrew H Crosby Sebahattin Cirak C Hellmuth O Uhl M Standl J Heinrich E Thiering B Koletzko Lena Blümel Kornelius Kerl Daniel Picard Michael C Frühwald Max C Liebau Guido Reifenberger Arndt Borkhardt Martin Hasselblatt Marc Remke D Tews M Wabitsch P Fischer-Posovszky Mike-Andrew Westhoff Lisa Nonnenmacher Julia Langhans Lukas Schneele Nancy Trenkler Klaus-Michael Debatin

Mol Cell Pediatr 2017 May;4(Suppl 1)

Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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http://dx.doi.org/10.1186/s40348-017-0071-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435609PMC
May 2017

Direct introduction of gene constructs into the pronucleus-like structure of cloned embryos: a new strategy for the generation of genetically modified pigs.

Transgenic Res 2017 04 10;26(2):309-318. Epub 2016 Dec 10.

Chair for Molecular Animal Breeding and Biotechnology, Center for Innovative Medical Models (CiMM), LMU Munich, Hackerstr. 27, 85764, Oberschleißheim, Germany.

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http://dx.doi.org/10.1007/s11248-016-0004-zDOI Listing
April 2017

Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.

Mol Metab 2017 03 6;6(3):256-266. Epub 2017 Jan 6.

Institute of Experimental Genetics, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD e.V.), Ingolstädter Landstraße 1, 85764 Neuherberg, Germany; Center of Life and Food Sciences Weihenstephan, Technische Universität München, Alte Akademie 8, 85354 Freising, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2016.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323884PMC
March 2017

Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).

J Am Assoc Lab Anim Sci 2016 ;55(4):375-86

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Germany; German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research, Neuherberg, Germany; Experimental Genetics, Center of Life and Food Sciences, Weihenstephan, Technische Universitaet Muenchen, Freising-Weihenstephan, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943607PMC
February 2017

Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD).

Sci Rep 2017 02 21;7:42970. Epub 2017 Feb 21.

Institute of Veterinary Pathology, Center for Clinical Veterinary Medicine, Ludwig-Maximilians-Universität München, D-80539 Munich, Germany.

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http://dx.doi.org/10.1038/srep42970DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318959PMC
February 2017

Loss of DRO1/CCDC80 results in obesity and promotes adipocyte differentiation.

Mol Cell Endocrinol 2017 01 16;439:286-296. Epub 2016 Sep 16.

Department of Medicine II, University of Munich, Munich, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Internal Medicine and Gastroenterology, HELIOS Klinikum Berlin-Buch, Berlin, Germany.

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http://dx.doi.org/10.1016/j.mce.2016.09.014DOI Listing
January 2017

Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium.

J Am Coll Cardiol 2017 Jan;69(2):131-143

I. Medizinische Klinik und Poliklinik, University Clinic Rechts der Isar, Technical University of Munich, Munich, Germany; DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany; Walter-Brendel-Centre for Experimental Medicine, Ludwig Maximilian University of Munich, Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2016.10.058DOI Listing
January 2017

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 2b: genetically modified source pigs.

Xenotransplantation 2016 Jan-Feb;23(1):32-7. Epub 2016 Mar 1.

Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1111/xen.12224DOI Listing
December 2016

Progress in Clinical Encapsulated Islet Xenotransplantation.

Transplantation 2016 Nov;100(11):2301-2308

1 Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA. 2 Otsuka Pharmaceutical Factory, Tateiwa, Muya-cho, Naruto Tokushima, Japan. 3 Hospital Eva Peron de San Martin, Buenos Aires, Argentina. 4 Department of Regenerative Medicine and Transplantation, Faculty of Medicine, Fukuoka University, Fukuoka City, Fukuoka, Japan. 5 Laboratory of Surgery and Transplantation, Catholic University of Louvain, Brussels, Belgium. 6 Gene Center, LMU Munich and German Center for Diabetes Research (DZD), Munich, Germany. 7 Transplantation Immunology Unit, Padua University Hospital, and the Consortium for Research in Organ Transplantation (CORIT), Padua, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5077652PMC
http://dx.doi.org/10.1097/TP.0000000000001371DOI Listing
November 2016

Transgenic Expression of Human Thrombomodulin Inhibits HMGB1-Induced Porcine Aortic Endothelial Cell Activation.

Transplantation 2016 09;100(9):1871-9

1 Immunology Research Centre, St. Vincent's Hospital Melbourne, Victoria, Australia. 2 Institute of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilian University, Munich, Germany. 3 Revivicor, Inc., Blacksburg, VA. 4 Department of Clinical Research, University of Bern, Bern, Switzerland. 5 Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1097/TP.0000000000001188DOI Listing
September 2016

Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.

Diabetes 2016 09 9;65(9):2540-52. Epub 2016 Jun 9.

Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany German Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany Center of Life and Food Sciences Weihenstephan, Technische Universität München, Freising, Germany

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http://diabetes.diabetesjournals.org/content/diabetes/early/
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http://dx.doi.org/10.2337/db15-1670DOI Listing
September 2016

A mouse model for ulcerative colitis based on NOD-scid IL2R γnull mice reconstituted with peripheral blood mononuclear cells from affected individuals.

Dis Model Mech 2016 09 4;9(9):985-97. Epub 2016 Aug 4.

Department of General- Visceral-, and Transplantation Surgery, Hospital of the University of Munich, Nussbaumstr. 20, Munich 80336, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5047691PMC
http://dx.doi.org/10.1242/dmm.025452DOI Listing
September 2016

Progressive muscle proteome changes in a clinically relevant pig model of Duchenne muscular dystrophy.

Sci Rep 2016 09 16;6:33362. Epub 2016 Sep 16.

Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, D-81377 Munich, Germany.

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http://dx.doi.org/10.1038/srep33362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5025886PMC
September 2016

Comparative aspects of rodent and nonrodent animal models for mechanistic and translational diabetes research.

Theriogenology 2016 Jul 21;86(1):406-21. Epub 2016 Apr 21.

Gene Center and Center for Innovative Medical Models (CiMM), Ludwig-Maximilians-Universität München, Munich, Germany; German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Neuherberg, Germany.

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http://dx.doi.org/10.1016/j.theriogenology.2016.04.055DOI Listing
July 2016

Stage-dependent remodeling of the nuclear envelope and lamina during rabbit early embryonic development.

J Reprod Dev 2016 Apr 4;62(2):127-35. Epub 2015 Dec 4.

Division of Anthropology and Human Genetics, Biocenter, LMU Munich, D-82152 Planegg-Martinsried, Germany.

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https://www.jstage.jst.go.jp/article/jrd/62/2/62_2015-100/_a
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http://dx.doi.org/10.1262/jrd.2015-100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848569PMC
April 2016

Tissue Sampling Guides for Porcine Biomedical Models.

Toxicol Pathol 2016 Apr 16;44(3):414-20. Epub 2016 Feb 16.

Institute of Veterinary Pathology, Center for Clinical Veterinary Medicine, Ludwig-Maximilians-Universität München, Munich, Germany

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http://dx.doi.org/10.1177/0192623316631023DOI Listing
April 2016

Inhibition of complement component C5 prevents clotting in an ex vivo model of xenogeneic activation of coagulation.

Xenotransplantation 2016 03 16;23(2):117-27. Epub 2016 Jan 16.

Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1111/xen.12218DOI Listing
March 2016

Growth hormone (GH)-transgenic insulin-like growth factor 1 (IGF1)-deficient mice allow dissociation of excess GH and IGF1 effects on glomerular and tubular growth.

Physiol Rep 2016 Mar;4(5)

Institute of Veterinary Pathology at the Centre for Clinical Veterinary Medicine, Ludwig-Maximilians-University Muenchen, Munich, Germany.

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http://doi.wiley.com/10.14814/phy2.12709
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http://dx.doi.org/10.14814/phy2.12709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823598PMC
March 2016

3D structured illumination microscopy of mammalian embryos and spermatozoa.

BMC Dev Biol 2015 Nov 26;15:46. Epub 2015 Nov 26.

Chair for Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, D-81377, Munich, Germany.

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http://www.biomedcentral.com/1471-213X/15/46
Publisher Site
http://dx.doi.org/10.1186/s12861-015-0092-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661982PMC
November 2015