Earl Gordon

Earl Gordon

UNVERIFIED PROFILE

Are you Earl Gordon?   Register this Author

Register author
Earl Gordon

Earl Gordon

Publications by authors named "Earl Gordon"

Are you Earl Gordon?   Register this Author

13Publications

69Reads

-Profile Views

Characterizing the role of Thr352 in the inhibition of the large conductance Ca2+-activated K+ channels by 1-[1-hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone.

J Pharmacol Exp Ther 2010 Aug 29;334(2):402-9. Epub 2010 Apr 29.

Metabolic Pathways Center of Excellence in Drug Discovery, GlaxoSmithKline Pharmaceuticals, King of Prussia, PA 19406, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/jpet.110.166017DOI Listing
August 2010

Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells.

Channels (Austin) 2009 May-Jun;3(3):156-60. Epub 2009 May 24.

Metabolic Pathways Center for Excellence in Drug Discovery, GlaxoSmithKline Pharmaceuticals, King of Prussia, PA 19406, USA.

View Article

Download full-text PDF

Source
November 2009

1-[1-Hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone, a potent and highly selective small molecule blocker of the large-conductance voltage-gated and calcium-dependent K+ channel.

J Pharmacol Exp Ther 2008 Oct 30;327(1):168-77. Epub 2008 Jun 30.

Metabolic Pathway Center of Excellence in Drug Discovery, GlaxoSmithKline, King of Prussia, Pennsylvania 19406, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/jpet.108.139733DOI Listing
October 2008

2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels.

Mol Pharmacol 2008 Mar 27;73(3):639-51. Epub 2007 Nov 27.

GlaxoSmithKline, 709 Swedeland Road, UW2511, P.O. Box 1539, King of Prussia, PA 19406, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.107.041152DOI Listing
March 2008

A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance.

Cardiovasc Res 2008 Jan 4;77(1):98-106. Epub 2007 Oct 4.

Greenberg Division of Cardiology, Department of Medicine, Weill Medical College, Cornell University, 520 East 70th Street, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/cardiovascres/article-lookup/doi/10
Publisher Site
http://dx.doi.org/10.1093/cvr/cvm030DOI Listing
January 2008

Acetic acid opens large-conductance Ca2+-activated K+ channels in guinea pig detrusor smooth muscle cells.

Eur J Pharmacol 2007 Jun 27;563(1-3):203-8. Epub 2007 Feb 27.

Department of Pharmaceutical Sciences, College of Pharmacy, North Dakota State University, Fargo ND 58105, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S001429990700247
Publisher Site
http://dx.doi.org/10.1016/j.ejphar.2007.02.037DOI Listing
June 2007

Influence of watershed system management on herbicide concentrations in Mississippi Delta oxbow lakes.

Sci Total Environ 2006 Nov 26;370(2-3):552-60. Epub 2006 Sep 26.

USDA Agricultural Research Service, Southern Weed Science Research Unit, Stoneville, MS 38776, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.scitotenv.2006.08.023DOI Listing
November 2006

1,4-Diazabicyclo[2.2.2]octane derivatives: a novel class of voltage-gated potassium channel blockers.

Mol Pharmacol 2006 Mar 29;69(3):718-26. Epub 2005 Nov 29.

Greenberg Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, 520 East 70th Street, New York, NY 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.105.018663DOI Listing
March 2006

Endogenous KCNE subunits govern Kv2.1 K+ channel activation kinetics in Xenopus oocyte studies.

Biophys J 2006 Feb 2;90(4):1223-31. Epub 2005 Dec 2.

Greenberg Division of Cardiology, Department of Medicine, Cornell University, Weill Medical College, New York 10021, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S000634950672313
Publisher Site
http://dx.doi.org/10.1529/biophysj.105.072504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1367273PMC
February 2006

RNA interference reveals that endogenous Xenopus MinK-related peptides govern mammalian K+ channel function in oocyte expression studies.

J Biol Chem 2003 Apr 15;278(14):11739-45. Epub 2003 Jan 15.

Division of Cardiology, Department of Medicine and Pharmacology, Graduate Program of Neuroscience, Weill Medical College of Cornell University, New York, New York 10021, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M212751200DOI Listing
April 2003