Duncan C Thomas

Duncan C Thomas

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Duncan C Thomas

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A Unified Model for the Analysis of Gene-Environment Interaction.

Am J Epidemiol 2019 Apr;188(4):760-767

Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1093/aje/kwy278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438805PMC
April 2019

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

Authors:
Stephanie L Schmit Christopher K Edlund Fredrick R Schumacher Jian Gong Tabitha A Harrison Jeroen R Huyghe Chenxu Qu Marilena Melas David J Van Den Berg Hansong Wang Stephanie Tring Sarah J Plummer Demetrius Albanes M Henar Alonso Christopher I Amos Kristen Anton Aaron K Aragaki Volker Arndt Elizabeth L Barry Sonja I Berndt Stéphane Bezieau Stephanie Bien Amanda Bloomer Juergen Boehm Marie-Christine Boutron-Ruault Hermann Brenner Stefanie Brezina Daniel D Buchanan Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Jose E Castelao Andrew T Chan Jenny Chang-Claude Stephen J Chanock Iona Cheng Ya-Wen Cheng Lee Soo Chin James M Church Timothy Church Gerhard A Coetzee Michelle Cotterchio Marcia Cruz Correa Keith R Curtis David Duggan Douglas F Easton Dallas English Edith J M Feskens Rocky Fischer Liesel M FitzGerald Barbara K Fortini Lars G Fritsche Charles S Fuchs Manuela Gago-Dominguez Manish Gala Steven J Gallinger W James Gauderman Graham G Giles Edward L Giovannucci Stephanie M Gogarten Clicerio Gonzalez-Villalpando Elena M Gonzalez-Villalpando William M Grady Joel K Greenson Andrea Gsur Marc Gunter Christopher A Haiman Jochen Hampe Sophia Harlid John F Harju Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Shu-Chen Huang Jose Maria Huerta Thomas J Hudson David J Hunter Gregory E Idos Motoki Iwasaki Rebecca D Jackson Eric J Jacobs Sun Ha Jee Mark A Jenkins Wei-Hua Jia Shuo Jiao Amit D Joshi Laurence N Kolonel Suminori Kono Charles Kooperberg Vittorio Krogh Tilman Kuehn Sébastien Küry Andrea LaCroix Cecelia A Laurie Flavio Lejbkowicz Mathieu Lemire Heinz-Josef Lenz David Levine Christopher I Li Li Li Wolfgang Lieb Yi Lin Noralane M Lindor Yun-Ru Liu Fotios Loupakis Yingchang Lu Frank Luh Jing Ma Christoph Mancao Frank J Manion Sanford D Markowitz Vicente Martin Koichi Matsuda Keitaro Matsuo Kevin J McDonnell Caroline E McNeil Roger Milne Antonio J Molina Bhramar Mukherjee Neil Murphy Polly A Newcomb Kenneth Offit Hanane Omichessan Domenico Palli Jesus P Paredes Cotoré Julyann Pérez-Mayoral Paul D Pharoah John D Potter Conghui Qu Leon Raskin Gad Rennert Hedy S Rennert Bridget M Riggs Clemens Schafmayer Robert E Schoen Thomas A Sellers Daniela Seminara Gianluca Severi Wei Shi David Shibata Xiao-Ou Shu Erin M Siegel Martha L Slattery Melissa Southey Zsofia K Stadler Mariana C Stern Sebastian Stintzing Darin Taverna Stephen N Thibodeau Duncan C Thomas Antonia Trichopoulou Shoichiro Tsugane Cornelia M Ulrich Franzel J B van Duijnhoven Bethany van Guelpan Joseph Vijai Jarmo Virtamo Stephanie J Weinstein Emily White Aung Ko Win Alicja Wolk Michael Woods Anna H Wu Kana Wu Yong-Bing Xiang Yun Yen Brent W Zanke Yi-Xin Zeng Ben Zhang Niha Zubair Sun-Seog Kweon Jane C Figueiredo Wei Zheng Loic Le Marchand Annika Lindblom Victor Moreno Ulrike Peters Graham Casey Li Hsu David V Conti Stephen B Gruber

J Natl Cancer Inst 2019 Feb;111(2):146-157

Department of Preventive Medicine, USC Norris Comprehensive Cancer Center.

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http://dx.doi.org/10.1093/jnci/djy099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555904PMC
February 2019

Discovery of common and rare genetic risk variants for colorectal cancer.

Authors:
Jeroen R Huyghe Stephanie A Bien Tabitha A Harrison Hyun Min Kang Sai Chen Stephanie L Schmit David V Conti Conghui Qu Jihyoun Jeon Christopher K Edlund Peyton Greenside Michael Wainberg Fredrick R Schumacher Joshua D Smith David M Levine Sarah C Nelson Nasa A Sinnott-Armstrong Demetrius Albanes M Henar Alonso Kristin Anderson Coral Arnau-Collell Volker Arndt Christina Bamia Barbara L Banbury John A Baron Sonja I Berndt Stéphane Bézieau D Timothy Bishop Juergen Boehm Heiner Boeing Hermann Brenner Stefanie Brezina Stephan Buch Daniel D Buchanan Andrea Burnett-Hartman Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Sergi Castellví-Bel Andrew T Chan Jenny Chang-Claude Stephen J Chanock Maria-Dolores Chirlaque Sang Hee Cho Charles M Connolly Amanda J Cross Katarina Cuk Keith R Curtis Albert de la Chapelle Kimberly F Doheny David Duggan Douglas F Easton Sjoerd G Elias Faye Elliott Dallas R English Edith J M Feskens Jane C Figueiredo Rocky Fischer Liesel M FitzGerald David Forman Manish Gala Steven Gallinger W James Gauderman Graham G Giles Elizabeth Gillanders Jian Gong Phyllis J Goodman William M Grady John S Grove Andrea Gsur Marc J Gunter Robert W Haile Jochen Hampe Heather Hampel Sophia Harlid Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Wan-Ling Hsu Wen-Yi Huang Thomas J Hudson David J Hunter Gemma Ibañez-Sanz Gregory E Idos Roxann Ingersoll Rebecca D Jackson Eric J Jacobs Mark A Jenkins Amit D Joshi Corinne E Joshu Temitope O Keku Timothy J Key Hyeong Rok Kim Emiko Kobayashi Laurence N Kolonel Charles Kooperberg Tilman Kühn Sébastien Küry Sun-Seog Kweon Susanna C Larsson Cecelia A Laurie Loic Le Marchand Suzanne M Leal Soo Chin Lee Flavio Lejbkowicz Mathieu Lemire Christopher I Li Li Li Wolfgang Lieb Yi Lin Annika Lindblom Noralane M Lindor Hua Ling Tin L Louie Satu Männistö Sanford D Markowitz Vicente Martín Giovanna Masala Caroline E McNeil Marilena Melas Roger L Milne Lorena Moreno Neil Murphy Robin Myte Alessio Naccarati Polly A Newcomb Kenneth Offit Shuji Ogino N Charlotte Onland-Moret Barbara Pardini Patrick S Parfrey Rachel Pearlman Vittorio Perduca Paul D P Pharoah Mila Pinchev Elizabeth A Platz Ross L Prentice Elizabeth Pugh Leon Raskin Gad Rennert Hedy S Rennert Elio Riboli Miguel Rodríguez-Barranco Jane Romm Lori C Sakoda Clemens Schafmayer Robert E Schoen Daniela Seminara Mitul Shah Tameka Shelford Min-Ho Shin Katerina Shulman Sabina Sieri Martha L Slattery Melissa C Southey Zsofia K Stadler Christa Stegmaier Yu-Ru Su Catherine M Tangen Stephen N Thibodeau Duncan C Thomas Sushma S Thomas Amanda E Toland Antonia Trichopoulou Cornelia M Ulrich David J Van Den Berg Franzel J B van Duijnhoven Bethany Van Guelpen Henk van Kranen Joseph Vijai Kala Visvanathan Pavel Vodicka Ludmila Vodickova Veronika Vymetalkova Korbinian Weigl Stephanie J Weinstein Emily White Aung Ko Win C Roland Wolf Alicja Wolk Michael O Woods Anna H Wu Syed H Zaidi Brent W Zanke Qing Zhang Wei Zheng Peter C Scacheri John D Potter Michael C Bassik Anshul Kundaje Graham Casey Victor Moreno Goncalo R Abecasis Deborah A Nickerson Stephen B Gruber Li Hsu Ulrike Peters

Nat Genet 2019 01 3;51(1):76-87. Epub 2018 Dec 3.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41588-018-0286-6
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http://dx.doi.org/10.1038/s41588-018-0286-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437PMC
January 2019

Re: Kheifets et al. (2017): Residential magnetic fields exposure and childhood leukemia: a population-based case-control study in California.

Authors:
Duncan C Thomas

Cancer Causes Control 2018 07 7;29(7):609-610. Epub 2018 May 7.

Department of Preventive Medicine, University of Southern California, 2001 N Soto St., Los Angeles, CA, 90089-9234, USA.

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http://dx.doi.org/10.1007/s10552-018-1037-9DOI Listing
July 2018

Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women's Environmental Cancer and Radiation Epidemiology Study.

J Clin Oncol 2018 05 5;36(15):1513-1520. Epub 2018 Apr 5.

Anne S. Reiner, Julia Sisti, Marinela Capanu, Mark Robson, Xiaolin Liang, Meghan Woods, and Jonine L. Bernstein, Memorial Sloan Kettering Cancer Center; Mark Robson, Cornell University; Roy Shore, New York University School of Medicine, New York, NY; Esther M. John, Cancer Prevention Institute of California, Fremont, and Stanford School of Medicine, Stanford; David V. Conti, Daniel O. Stram, and Duncan C. Thomas, University of Southern California, Los Angeles; Leslie Bernstein, City of Hope National Medical Center, Duarte, CA; Charles F. Lynch, University of Iowa, Iowa City, IA; Jennifer D. Brooks and Julia A. Knight, University of Toronto; Julia A. Knight, Sinai Health System, Toronto, Ontario, Canada; Lene Mellemkjær, Danish Cancer Society Research Center, Copenhagen, Denmark; John D. Boice, Vanderbilt University Medical Center and the Vanderbilt-Ingram Cancer Center, Nashville, TN; Patrick Concannon, University of Florida, Gainesville, FL; Marc Tischkowitz, University of Cambridge, Cambridge, United Kingdom; David Duggan, Translational Genomics Research Institute, Phoenix, AZ; and Kathleen E. Malone, Fred Hutchinson Cancer Research Center, Seattle, WA.

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http://dx.doi.org/10.1200/JCO.2017.77.3424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959199PMC
May 2018

What Does "Precision Medicine" Have to Say About Prevention?

Authors:
Duncan C Thomas

Epidemiology 2017 07;28(4):479-483

From the Department of Preventive Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/EDE.0000000000000667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453815PMC
July 2017

Estimating the Effect of Targeted Screening Strategies: An Application to Colonoscopy and Colorectal Cancer.

Authors:
Duncan C Thomas

Epidemiology 2017 07;28(4):470-478

From the Department of Preventive Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/EDE.0000000000000668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453827PMC
July 2017

Inclusion of biological knowledge in a Bayesian shrinkage model for joint estimation of SNP effects.

Genet Epidemiol 2017 05 10;41(4):320-331. Epub 2017 Apr 10.

National Heart and Lung Institute, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1002/gepi.22038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397385PMC
May 2017

Linkage Analysis of Urine Arsenic Species Patterns in the Strong Heart Family Study.

Toxicol Sci 2015 Nov 23;148(1):89-100. Epub 2015 Jul 23.

Department of Environmental Health Sciences, Johns Hopkins University, Baltimore, Maryland; Department of Epidemiology, Johns Hopkins Medical Institutions, Baltimore, Maryland; Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Medical Institutions, Baltimore, Maryland; Department of Oncology, Johns Hopkins Medical Institutions, Baltimore, Maryland.

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http://dx.doi.org/10.1093/toxsci/kfv164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731407PMC
November 2015

Corrigendum: genome-wide association study of colorectal cancer identifies six new susceptibility loci.

Authors:
Fredrick R Schumacher Stephanie L Schmit Shuo Jiao Christopher K Edlund Hansong Wang Ben Zhang Li Hsu Shu-Chen Huang Christopher P Fischer John F Harju Gregory E Idos Flavio Lejbkowicz Frank J Manion Kevin McDonnell Caroline E McNeil Marilena Melas Hedy S Rennert Wei Shi Duncan C Thomas David J Van Den Berg Carolyn M Hutter Aaron K Aragaki Katja Butterbach Bette J Caan Christopher S Carlson Stephen J Chanock Keith R Curtis Charles S Fuchs Manish Gala Edward L Giovannucci Stephanie M Gogarten Richard B Hayes Brian Henderson David J Hunter Rebecca D Jackson Laurence N Kolonel Charles Kooperberg Sébastien Küry Andrea LaCroix Cathy C Laurie Cecelia A Laurie Mathieu Lemire David Levine Jing Ma Karen W Makar Conghui Qu Darin Taverna Cornelia M Ulrich Kana Wu Suminori Kono Dee W West Sonja I Berndt Stephane Bezieau Hermann Brenner Peter T Campbell Andrew T Chan Jenny Chang-Claude Gerhard A Coetzee David V Conti David Duggan Jane C Figueiredo Barbara K Fortini Steven J Gallinger W James Gauderman Graham Giles Roger Green Robert Haile Tabitha A Harrison Michael Hoffmeister John L Hopper Thomas J Hudson Eric Jacobs Motoki Iwasaki Sun Ha Jee Mark Jenkins Wei-Hua Jia Amit Joshi Li Li Noralene M Lindor Keitaro Matsuo Victor Moreno Bhramar Mukherjee Polly A Newcomb John D Potter Leon Raskin Gad Rennert Stephanie Rosse Gianluca Severi Robert E Schoen Daniela Seminara Xiao-Ou Shu Martha L Slattery Shoichiro Tsugane Emily White Yong-Bing Xiang Brent W Zanke Wei Zheng Loic Le Marchand Graham Casey Stephen B Gruber Ulrike Peters

Nat Commun 2015 Oct 26;6:8739. Epub 2015 Oct 26.

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http://dx.doi.org/10.1038/ncomms9739DOI Listing
October 2015

Genome-wide association study of colorectal cancer identifies six new susceptibility loci.

Authors:
Fredrick R Schumacher Stephanie L Schmit Shuo Jiao Christopher K Edlund Hansong Wang Ben Zhang Li Hsu Shu-Chen Huang Christopher P Fischer John F Harju Gregory E Idos Flavio Lejbkowicz Frank J Manion Kevin McDonnell Caroline E McNeil Marilena Melas Hedy S Rennert Wei Shi Duncan C Thomas David J Van Den Berg Carolyn M Hutter Aaron K Aragaki Katja Butterbach Bette J Caan Christopher S Carlson Stephen J Chanock Keith R Curtis Charles S Fuchs Manish Gala Edward L Giovannucci Stephanie M Gogarten Richard B Hayes Brian Henderson David J Hunter Rebecca D Jackson Laurence N Kolonel Charles Kooperberg Sébastien Küry Andrea LaCroix Cathy C Laurie Cecelia A Laurie Mathieu Lemire David Levine Jing Ma Karen W Makar Conghui Qu Darin Taverna Cornelia M Ulrich Kana Wu Suminori Kono Dee W West Sonja I Berndt Stéphane Bezieau Hermann Brenner Peter T Campbell Andrew T Chan Jenny Chang-Claude Gerhard A Coetzee David V Conti David Duggan Jane C Figueiredo Barbara K Fortini Steven J Gallinger W James Gauderman Graham Giles Roger Green Robert Haile Tabitha A Harrison Michael Hoffmeister John L Hopper Thomas J Hudson Eric Jacobs Motoki Iwasaki Sun Ha Jee Mark Jenkins Wei-Hua Jia Amit Joshi Li Li Noralene M Lindor Keitaro Matsuo Victor Moreno Bhramar Mukherjee Polly A Newcomb John D Potter Leon Raskin Gad Rennert Stephanie Rosse Gianluca Severi Robert E Schoen Daniela Seminara Xiao-Ou Shu Martha L Slattery Shoichiro Tsugane Emily White Yong-Bing Xiang Brent W Zanke Wei Zheng Loic Le Marchand Graham Casey Stephen B Gruber Ulrike Peters

Nat Commun 2015 Jul 7;6:7138. Epub 2015 Jul 7.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98124, USA.

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http://dx.doi.org/10.1038/ncomms8138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967357PMC
July 2015

Two-stage family-based designs for sequencing studies.

BMC Proc 2014 17;8(Suppl 1):S32. Epub 2014 Jun 17.

Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089-9234, USA.

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http://dx.doi.org/10.1186/1753-6561-8-S1-S32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143728PMC
December 2014

Complex pedigrees in the sequencing era: to track transmissions or decorrelate?

Genet Epidemiol 2014 Sep;38 Suppl 1:S29-36

Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1002/gepi.21822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272198PMC
September 2014

Comprehensive analyses of DNA repair pathways, smoking and bladder cancer risk in Los Angeles and Shanghai.

Int J Cancer 2014 Jul 13;135(2):335-47. Epub 2014 Jan 13.

Department of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1002/ijc.28693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4016180PMC
July 2014

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

Cancer Epidemiol Biomarkers Prev 2014 Apr 3;23(4):658-69. Epub 2014 Feb 3.

Authors' Affiliations: Center for Cancer Epidemiology and Prevention; Departments of Health Studies, Medicine, and Human Genetics; Comprehensive Cancer Center, University of Chicago, Chicago, Illinois; Department of Health Research and Policy, Stanford University School of Medicine; Stanford Cancer Institute, Stanford; Cancer Prevention Institute of California, Fremont; Department of Preventive Medicine, University of Southern California, Los Angeles; Stanford Cancer Institute, Palo Alto, California; Epidemiology and Genetics Research Program; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York; Integrated Cancer Genomics Division, Translational Genomics Research Institute, Phoenix; Department of Health Science Research, Mayo Clinic Arizona, Scottsdale, Arizona; Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg; Clinic of Gynaecology and Obstetrics, Division for Gynaecological Tumor-Genetics, Technische Universität München; Max Planck Institute of Psychiatry, Munich; Department of Obstetrics and Gynaecology, Division of Molecular Gynaeco-Oncology, PMV Research Group at the Department of Child and Adolescent Psychiatry and Psychotherapy, University of Cologne; Foundation for Quality and Efficiency in Health Care, Cologne; Department of Cancer Epidemiology/Clinical Cancer Registry; Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, Hamburg; Department of Psychiatry, University of Mainz, Mainz, Germany; Samuel Lunenfeld Research Institute; Zane Cohen Cen

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990360PMC
April 2014

Three authors reply.

Am J Epidemiol 2014 Apr 19;179(8):1037. Epub 2014 Mar 19.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1093/aje/kwu042DOI Listing
April 2014

Invited commentary: is it time to retire the "pack-years" variable? Maybe not!

Authors:
Duncan C Thomas

Am J Epidemiol 2014 Feb 18;179(3):299-302. Epub 2013 Dec 18.

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http://dx.doi.org/10.1093/aje/kwt274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895098PMC
February 2014

A Bayesian Hierarchical Model for Relating Multiple SNPs within Multiple Genes to Disease Risk.

Int J Genomics 2013 31;2013:406217. Epub 2013 Dec 31.

Division of Biostatistics, Department of Preventive Medicine, University of Southern California (USC), 2001 N. Soto Street, Los Angeles, CA, USA.

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http://dx.doi.org/10.1155/2013/406217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892936PMC
February 2014

Two-phase and family-based designs for next-generation sequencing studies.

Front Genet 2013 Dec 13;4:276. Epub 2013 Dec 13.

Department of Preventive Medicine, University of Southern California Los Angeles, CA, USA.

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http://dx.doi.org/10.3389/fgene.2013.00276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861783PMC
December 2013

Measurement Error in Spatial Exposure Models: Study Design Implications.

Authors:
Duncan C Thomas

Environmetrics 2013 Dec;24(8):518-520

Department of Preventive Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1002/env.2243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979582PMC
December 2013

Joint analysis for integrating two related studies of different data types and different study designs using hierarchical modeling approaches.

Hum Hered 2012 18;74(2):83-96. Epub 2013 Jan 18.

Division of Biostatistics, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1159/000345181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4106669PMC
September 2013

Efficient two-step testing of gene-gene interactions in genome-wide association studies.

Genet Epidemiol 2013 Jul 30;37(5):440-51. Epub 2013 Apr 30.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90032, USA.

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http://dx.doi.org/10.1002/gepi.21720DOI Listing
July 2013

Analysis and optimal design for association studies using next-generation sequencing with case-control pools.

Genet Epidemiol 2012 Dec 12;36(8):870-81. Epub 2012 Sep 12.

Department of Preventive Medicine, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1002/gepi.21681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4139478PMC
December 2012

Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationships.

Hum Genet 2012 Oct 28;131(10):1565-89. Epub 2012 Jun 28.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USC Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1007/s00439-012-1189-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432200PMC
October 2012

Invited commentary: GE-Whiz! Ratcheting gene-environment studies up to the whole genome and the whole exposome.

Am J Epidemiol 2012 Feb 22;175(3):203-7; discussion 208-9. Epub 2011 Dec 22.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1093/aje/kwr365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261438PMC
February 2012

Two-stage design of sequencing studies for testing association with rare variants.

Hum Hered 2011 2;71(4):209-20. Epub 2011 Jul 2.

Department of Preventive Medicine, University of Southern California, Los Angeles, USA.

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http://dx.doi.org/10.1159/000328193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136374PMC
December 2011

Incorporating model uncertainty in detecting rare variants: the Bayesian risk index.

Genet Epidemiol 2011 Nov 26;35(7):638-49. Epub 2011 Aug 26.

Department of Preventive Medicine, Division of Biostatistics, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1002/gepi.20613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936341PMC
November 2011

Sample size requirements to detect gene-environment interactions in genome-wide association studies.

Genet Epidemiol 2011 Apr 9;35(3):201-10. Epub 2011 Feb 9.

Department of Preventive Medicine, University of Southern California, Los Angeles, California 90089-9010, USA.

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http://dx.doi.org/10.1002/gepi.20569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076801PMC
April 2011

Using biological knowledge to discover higher order interactions in genetic association studies.

Genet Epidemiol 2010 Dec;34(8):863-78

Division of Biostatics, Department of Preventive Medicine, University of Southern California, Los Angeles, California 90089-9601, USA.

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http://doi.wiley.com/10.1002/gepi.20542
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http://dx.doi.org/10.1002/gepi.20542DOI Listing
December 2010

Complex system approaches to genetic analysis Bayesian approaches.

Adv Genet 2010 ;72:47-71

Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1016/B978-0-12-380862-2.00003-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4190044PMC
November 2010

Discovery of complex pathways from observational data.

Stat Med 2010 Aug;29(19):1998-2011

Department of Preventive Medicine, University of Southern California, Los Angeles, USA.

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http://dx.doi.org/10.1002/sim.3962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2922970PMC
August 2010

Efficient genome-wide association testing of gene-environment interaction in case-parent trios.

Am J Epidemiol 2010 Jul 11;172(1):116-22. Epub 2010 Jun 11.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, 90033, USA.

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http://dx.doi.org/10.1093/aje/kwq097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915477PMC
July 2010

Genome-wide association studies for discrete traits.

Authors:
Duncan C Thomas

Genet Epidemiol 2009 ;33 Suppl 1:S8-12

Department of Preventive Medicine, University of Southern California, Los Angeles, California 90089-9011, USA.

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http://doi.wiley.com/10.1002/gepi.20465
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http://dx.doi.org/10.1002/gepi.20465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920891PMC
March 2010

Bayesian hierarchical modeling of means and covariances of gene expression data within families.

BMC Proc 2007 18;1 Suppl 1:S111. Epub 2007 Dec 18.

Department of Preventive Medicine, University of Southern California, 1540 Alcazar Street, CHP-220, Los Angeles, California 90089, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367475PMC
http://dx.doi.org/10.1186/1753-6561-1-s1-s111DOI Listing
December 2009

Methodological Issues in Multistage Genome-wide Association Studies.

Stat Sci 2009 Nov;24(4):414-429

Department of Preventive Medicine, University of Southern California.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895324PMC
November 2009

Use of pathway information in molecular epidemiology.

Hum Genomics 2009 Oct;4(1):21-42

Department of Preventive Medicine, University of Southern California, 1540 Alcazar St., CHP-220, Los Angeles, CA 90089-9011, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2999471PMC
October 2009

Gene-trait similarity regression for multimarker-based association analysis.

Biometrics 2009 Sep 4;65(3):822-32. Epub 2009 Feb 4.

Department of Statistics, North Carolina State University, Raleigh, North Carolina 27695, USA.

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http://dx.doi.org/10.1111/j.1541-0420.2008.01176.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2748404PMC
September 2009

Approaches to complex pathways in molecular epidemiology: summary of a special conference of the American Association for Cancer Research.

Cancer Res 2008 Dec;68(24):10028-30

Department of Preventive Medicine, University of Southern California, Los Angeles, California 90089-9011, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-1690DOI Listing
December 2008

Design considerations in a sib-pair study of linkage for susceptibility loci in cancer.

BMC Med Genet 2008 Jul 10;9:64. Epub 2008 Jul 10.

Population Sciences Program, Hunstman Cancer Institute, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1186/1471-2350-9-64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488325PMC
July 2008

Hierarchical Bayes prioritization of marker associations from a genome-wide association scan for further investigation.

Genet Epidemiol 2007 Dec;31(8):871-82

Department of Preventive Medicine, University of Southern California, Los Angeles, California 90089-9011, USA.

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http://dx.doi.org/10.1002/gepi.20248DOI Listing
December 2007

Multistage sampling for latent variable models.

Authors:
Duncan C Thomas

Lifetime Data Anal 2007 Dec 18;13(4):565-81. Epub 2007 Oct 18.

Department of Preventive Medicine, University of Southern California, 1540 Alcazar St., CHP-220, Los Angeles, CA 90089-9011, USA.

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http://dx.doi.org/10.1007/s10985-007-9061-1DOI Listing
December 2007

Viewpoint: using gene-environment interactions to dissect the effects of complex mixtures.

Authors:
Duncan C Thomas

J Expo Sci Environ Epidemiol 2007 Dec;17 Suppl 2:S71-4

Department of Preventive Medicine, University of Southern California, 1540 Alcazar Street, CHP-220, Los Angeles, California 90089-9011, USA.

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http://www.nature.com/articles/7500630
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http://dx.doi.org/10.1038/sj.jes.7500630DOI Listing
December 2007

Dissecting effects of complex mixtures: who's afraid of informative priors?

Epidemiology 2007 Mar;18(2):186-90

Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089-9011, USA.

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http://dx.doi.org/10.1097/01.ede.0000254682.47697.70DOI Listing
March 2007

Bayesian model averaging in time-series studies of air pollution and mortality.

J Toxicol Environ Health A 2007 Feb;70(3-4):311-5

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089-9011, USA.

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http://dx.doi.org/10.1080/15287390600884941DOI Listing
February 2007

An utter refutation of the "Fundamental Theorem of the HapMap" by Terwilliger and Hiekkalinna.

Eur J Hum Genet 2006 Dec 2;14(12):1238-9. Epub 2006 Aug 2.

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http://dx.doi.org/10.1038/sj.ejhg.5201697DOI Listing
December 2006

High-volume "-omics" technologies and the future of molecular epidemiology.

Authors:
Duncan C Thomas

Epidemiology 2006 Sep;17(5):490-1

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1097/01.ede.0000229950.29674.68DOI Listing
September 2006

Optimal two-stage genotyping designs for genome-wide association scans.

Genet Epidemiol 2006 May;30(4):356-68

Division of Biostatistics and Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

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http://dx.doi.org/10.1002/gepi.20150DOI Listing
May 2006

Are we ready for genome-wide association studies?

Authors:
Duncan C Thomas

Cancer Epidemiol Biomarkers Prev 2006 Apr;15(4):595-8

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http://dx.doi.org/10.1158/1055-9965.EPI-06-0146DOI Listing
April 2006

Recent developments in genomewide association scans: a workshop summary and review.

Am J Hum Genet 2005 Sep 1;77(3):337-45. Epub 2005 Aug 1.

Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089-9011, USA.

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http://dx.doi.org/10.1086/432962DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1226200PMC
September 2005

BRCA1 variants in a family study of African-American and Latina women.

Hum Genet 2005 May 23;116(6):497-506. Epub 2005 Feb 23.

Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, 1441 Eastlake Avenue MS 44, Los Angeles, CA 90089-9175, USA.

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http://dx.doi.org/10.1007/s00439-004-1240-5DOI Listing
May 2005

A three-level model for binary time-series data: the effects of air pollution on school absences in the Southern California Children's Health Study.

Stat Med 2005 Apr;24(7):1103-15

Institut National de la Santé et de la Recherche Médicale, Equipe Mixte INSERM E03 38 (Biostatistique), Université Bordeaux2, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France.

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http://dx.doi.org/10.1002/sim.1980DOI Listing
April 2005

The need for a systematic approach to complex pathways in molecular epidemiology.

Authors:
Duncan C Thomas

Cancer Epidemiol Biomarkers Prev 2005 Mar;14(3):557-9

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http://dx.doi.org/10.1158/1055-9965.EPI-14-3-EDBDOI Listing
March 2005

Case-sibling gene-association studies for diseases with variable age at onset.

Stat Med 2004 Dec;23(23):3697-712

Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1002/sim.1722DOI Listing
December 2004