Drew M Pardoll

Drew M Pardoll

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Drew M Pardoll

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Extreme responses to immune checkpoint blockade following bipolar androgen therapy and enzalutamide in patients with metastatic castration resistant prostate cancer.

Prostate 2020 04 23;80(5):407-411. Epub 2020 Jan 23.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.23955DOI Listing
April 2020

An Immunogenomic Investigation of Oral Cavity Squamous Cell Carcinoma in Patients Aged 45 Years and Younger.

Laryngoscope 2020 Apr 16. Epub 2020 Apr 16.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, U.S.A.

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http://dx.doi.org/10.1002/lary.28674DOI Listing
April 2020

YAP Attenuates CD8 T Cell-Mediated Anti-tumor Response.

Front Immunol 2020 8;11:580. Epub 2020 Apr 8.

Immunology and Hematopoiesis Division, Department of Oncology, Bloomberg-Kimmel Institute, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MA, United States.

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http://dx.doi.org/10.3389/fimmu.2020.00580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158852PMC
April 2020

Biomimetic anisotropic polymeric nanoparticles coated with red blood cell membranes for enhanced circulation and toxin removal.

Sci Adv 2020 Apr 15;6(16):eaay9035. Epub 2020 Apr 15.

Departments of Biomedical Engineering, Materials Science and Engineering, Chemical and Biomolecular Engineering, and Oncology, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins School of Medicine, 400 N Broadway, Smith Building 5017, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1126/sciadv.aay9035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239698PMC
April 2020

Kidney retransplantation after anti-programmed cell death-1 (PD-1)-related allograft rejection.

Am J Transplant 2020 Mar 17. Epub 2020 Mar 17.

Department of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1111/ajt.15856DOI Listing
March 2020

Neoadjuvant checkpoint blockade for cancer immunotherapy.

Science 2020 01;367(6477)

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1126/science.aax0182DOI Listing
January 2020

Pan-Cancer Analysis of Loss-of-Function Alterations and Their Association with the Focal Tandem-Duplicator Phenotype.

Oncologist 2019 12 10;24(12):1526-1533. Epub 2019 Jul 10.

Johns Hopkins University School of Medicine and Bloomberg-Kimmel Institute for Cancer Immunotherapy, Baltimore, Maryland, USA

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http://dx.doi.org/10.1634/theoncologist.2019-0214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975947PMC
December 2019

Oral antibiotic use and risk of colorectal cancer in the United Kingdom, 1989-2012: a matched case-control study.

Gut 2019 11 19;68(11):1971-1978. Epub 2019 Aug 19.

The Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1136/gutjnl-2019-318593DOI Listing
November 2019

Mechanisms regulating PD-L1 expression on tumor and immune cells.

J Immunother Cancer 2019 11 15;7(1):305. Epub 2019 Nov 15.

Department of Surgery, Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center, and Bloomberg~Kimmel Institute for Cancer Immunotherapy, Baltimore, MD, 21287, USA.

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http://dx.doi.org/10.1186/s40425-019-0770-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858680PMC
November 2019

Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis.

Sci Immunol 2019 10;4(40)

Translational Tissue Engineering Center, Wilmer Eye Institute, and Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1126/sciimmunol.aax4783DOI Listing
October 2019

Genomic and clinical characterization of pulmonary-only metastatic prostate cancer: A unique molecular subtype.

Prostate 2019 09 7;79(13):1572-1579. Epub 2019 Aug 7.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland.

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http://dx.doi.org/10.1002/pros.23881DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147974PMC
September 2019

Clinical Features and Therapeutic Outcomes in Men with Advanced Prostate Cancer and DNA Mismatch Repair Gene Mutations.

Eur Urol 2019 03 15;75(3):378-382. Epub 2018 Oct 15.

Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03022838183075
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http://dx.doi.org/10.1016/j.eururo.2018.10.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377812PMC
March 2019

Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic.

J Clin Invest 2019 03 11;129(4):1699-1712. Epub 2019 Mar 11.

Bloomberg-Kimmel Institute for Immunotherapy, Departments of Oncology and Medicine and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1172/JCI124196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436866PMC
March 2019

Divergent immune responses to synthetic and biological scaffolds.

Biomaterials 2019 02 9;192:405-415. Epub 2018 Nov 9.

Translational Tissue Engineering Center, Wilmer Eye Institute, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Bloomberg∼Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2018.11.002DOI Listing
February 2019

The prognostic impact of pathologic lymph nodes in HPV-positive oropharyngeal cancers.

Oral Oncol 2019 02 15;89:23-29. Epub 2018 Dec 15.

The Bloomberg-Kimmel Institute for Cancer Immunotherapy, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Johns Hopkins Division of Biostatistics and Bioinformatics, Johns Hopkins University School of Medicine, 550 North Broadway, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.oraloncology.2018.12.005DOI Listing
February 2019

ExCYT: A Graphical User Interface for Streamlining Analysis of High-Dimensional Cytometry Data.

J Vis Exp 2019 01 16(143). Epub 2019 Jan 16.

The Bloomberg~Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine; Department of Pathology, Johns Hopkins University School of Medicine;

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http://dx.doi.org/10.3791/57473DOI Listing
January 2019

Neoadjuvant PD-1 Blockade in Resectable Lung Cancer.

N Engl J Med 2018 May 16;378(21):1976-1986. Epub 2018 Apr 16.

From the Bloomberg-Kimmel Institute for Cancer Immunotherapy and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore (P.M.F., K.N.S., V.A., T.R.C., M.Z., S.C.Y., S.B., R.J.B., J.N., K.A.M., F.V., H.G., J.Z., J.X.C., H.Y.C., J.-W.S., R.B.S., J.W., E.G., H.W., G.L.R., J.M.T., V.E.V., S.L.T., J.R.B., D.M.P.); Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine (J.E.C., M.D.H., D.R.J., M.J.V., N.R., Z.O., V.R., J.D.W., T.M.) and the Ludwig Collaborative (J.D.W., T.M.) - all in New York; the Parker Institute for Cancer Immunotherapy, San Francisco (J.D.W., T.M.); and Swim Across America Laboratory, Charlotte, NC (J.D.W., T.M.).

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http://www.nejm.org/doi/10.1056/NEJMoa1716078
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http://dx.doi.org/10.1056/NEJMoa1716078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223617PMC
May 2018

The intestinal microbiome influences checkpoint blockade.

Nat Med 2018 03;24(3):254-255

Bloomberg-Kimmel Institute for Immunotherapy, Johns Hopkins University School of Medicine, Balitmore, Maryland, USA.

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http://dx.doi.org/10.1038/nm.4511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435254PMC
March 2018

Biodegradable STING agonist nanoparticles for enhanced cancer immunotherapy.

Nanomedicine 2018 02 7;14(2):237-246. Epub 2017 Nov 7.

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Otolaryngology / Head & Neck Surgery, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2017.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035751PMC
February 2018

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

Cell Host Microbe 2018 Feb 1;23(2):203-214.e5. Epub 2018 Feb 1.

Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2018.01.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954996PMC
February 2018

The Scaffold Immune Microenvironment: Biomaterial-Mediated Immune Polarization in Traumatic and Nontraumatic Applications.

Tissue Eng Part A 2017 10 9;23(19-20):1044-1053. Epub 2016 Nov 9.

1 Translational Tissue Engineering Center, Department of Biomedical Engineering, Johns Hopkins University School of Medicine , Baltimore, Maryland.

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http://dx.doi.org/10.1089/ten.TEA.2016.0304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436021PMC
October 2017

Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors.

Proc Natl Acad Sci U S A 2016 11 11;113(48):E7769-E7777. Epub 2016 Nov 11.

Department of Oncology, The Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287;

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http://dx.doi.org/10.1073/pnas.1607836113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137776PMC
November 2016

MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor.

Immunity 2016 07;45(1):83-93

Immunology and Hematopoiesis Division, Department of Oncology, Bloomberg-Kimmel Institute, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957244PMC
July 2016

PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma.

N Engl J Med 2016 Jun 19;374(26):2542-52. Epub 2016 Apr 19.

From the University of Washington Medical Center (P.T.N., S. Bhatia, N.J.M., E.M.S., M.M.S., J.A.T., M.A.C.), Fred Hutchinson Cancer Research Center (P.T.N., S. Bhatia, S.P.F., L.L., J.A.T., M.A.C.), Cancer Immunotherapy Trials Network (S.P.F., L.L., M.A.C.), and Cancer Research and Biostatistics (A.M., L.R.S.) - all in Seattle; Johns Hopkins University School of Medicine and Kimmel Cancer Center, Baltimore (E.J.L., S. Berry, D.M.P., W.H.S., J.C.S., J.M.T., S.L.T.), and Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda. (E.S.) - both in Maryland; Winship Cancer Institute of Emory University, Atlanta (R.R.K.); Merck Research Laboratories, Kenilworth, NJ (L.A., E.K.C., S.M.T., J.H.Y.); University of California, San Francisco, San Francisco (A.D.), and Stanford University, Stanford (H.E.K., K.M., S.A.R.) - both in California; Mt. Sinai Medical Center, New York (P.A.F.); Yale University, New Haven, CT (H.M.K.); and Ohio State University, Columbus (T.O.).

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http://dx.doi.org/10.1056/NEJMoa1603702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927341PMC
June 2016

Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy.

Nat Rev Cancer 2016 05 15;16(5):275-87. Epub 2016 Apr 15.

Department of Oncology, Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center and Bloomberg-Kimmel Institute for Cancer Immunotherapy, 1550 Orleans Street, CRB2 Room 508, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1038/nrc.2016.36DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381938PMC
May 2016

Erratum to: PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment.

J Neurooncol 2016 05;128(1):183

Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/s11060-016-2130-0DOI Listing
May 2016

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis.

Cancer Res 2016 04 15;76(8):2115-24. Epub 2016 Feb 15.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-0749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873376PMC
April 2016

Developing a pro-regenerative biomaterial scaffold microenvironment requires T helper 2 cells.

Science 2016 Apr;352(6283):366-70

Translational Tissue Engineering Center, Wilmer Eye Institute and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21287, USA. Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.aad9272
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http://dx.doi.org/10.1126/science.aad9272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866509PMC
April 2016

Regulatory T-cell Response to Enterotoxigenic Bacteroides fragilis Colonization Triggers IL17-Dependent Colon Carcinogenesis.

Cancer Discov 2015 Oct 22;5(10):1098-109. Epub 2015 Jul 22.

Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592451PMC
October 2015

Concepts of immunotherapy for glioma.

J Neurooncol 2015 Jul 13;123(3):323-30. Epub 2015 Jun 13.

Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.

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http://link.springer.com/10.1007/s11060-015-1810-5
Publisher Site
http://dx.doi.org/10.1007/s11060-015-1810-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498978PMC
July 2015

Ubiquitin-dependent regulation of Foxp3 and Treg function.

Immunol Rev 2015 Jul;266(1):27-45

Immunology and Hematopoiesis Division, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/imr.12312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930875PMC
July 2015

Survival, Durable Response, and Long-Term Safety in Patients With Previously Treated Advanced Renal Cell Carcinoma Receiving Nivolumab.

J Clin Oncol 2015 Jun 30;33(18):2013-20. Epub 2015 Mar 30.

David F. McDermott, Beth Israel Deaconess Medical Center; Toni K. Choueiri, Dana-Farber Cancer Institute/Brigham and Women's Hospital; Igor Puzanov and F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Charles G. Drake, Julie R. Brahmer, Hans J. Hammers, Suzanne L. Topalian, and Drew M. Pardoll, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD; Mario Sznol, Yale University School of Medicine and Smilow Cancer Center, Yale-New Haven Hospital, New Haven, CT; John D. Powderly, Carolina BioOncology Institute, Huntersville, NC; David C. Smith, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Richard D. Carvajal, Memorial Sloan-Kettering Cancer Center, New York, NY; Jon M. Wigginton, Georgia D. Kollia, Ashok Gupta, Dan McDonald, and Vindira Sankar, Bristol-Myers Squibb, Princeton, NJ; Jeffrey A. Sosman, Vanderbilt-Ingram Cancer Center, Nashville, TN; and Michael B. Atkins, Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC.

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http://dx.doi.org/10.1200/JCO.2014.58.1041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517051PMC
June 2015

Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.

J Clin Oncol 2015 Jun 20;33(18):2004-12. Epub 2015 Apr 20.

Scott N. Gettinger and Mario Sznol, Yale Cancer Center, New Haven, CT; Leora Horn, David P. Carbone, and Jeffrey A. Sosman, Vanderbilt University Medical Center; David R. Spigel, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Leena Gandhi, David M. Jackman, and F. Stephen Hodi, Dana-Farber Cancer Institute; Rebecca S. Heist and Lecia V. Sequist, Massachusetts General Hospital Cancer Center; David F. McDermott, Beth Israel Deaconess Medical Center, Boston, MA; Scott J. Antonia and Mary C. Pinder-Schenck, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; Naiyer A. Rizvi, Richard D. Carvajal, and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center, New York, NY; John D. Powderly, Carolina BioOncology Institute, Huntersville, NC; David C. Smith, University of Michigan, Ann Arbor, MI; Philip Leming, Christ Hospital Cancer Center, Cincinnati, OH; Suzanne L. Topalian, Drew M. Pardoll, and Julie R. Brahmer, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins, Baltimore, MD; and Vindira Sankar, Christoph M. Ahlers, Mark Salvati, Jon M. Wigginton, Georgia D. Kollia, and Ashok K. Gupta, Bristol-Myers Squibb, Princeton, NJ.

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http://jco.ascopubs.org/content/early/2015/04/15/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.3708
Publisher Site
http://dx.doi.org/10.1200/JCO.2014.58.3708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672027PMC
June 2015

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

N Engl J Med 2015 Jun 30;372(26):2509-20. Epub 2015 May 30.

From the Swim Across America Laboratory (D.T.L., J.N.U., B.R.B., L.A.D.), Sidney Kimmel Comprehensive Cancer Center (D.T.L., J.N.U., H.W., H.K., A.D.E., A.D.S., B.S.L., N.S.A., D.L., B.B., R.C.D., D.M.P., N.P., K.W.K., S.Z., B.V., L.A.D.), Ludwig Center and Howard Hughes Medical Institute (B.R.B., A.D.S., N.P., K.W.K., S.Z., B.V., L.A.D.), and the Departments of Radiology (A.Z.) and Pathology (F.B., T.H., R.H.H., L.D.W., N.C., T.C.C., J.M.T., R.A.A., J.R.E.), Johns Hopkins University School of Medicine, Baltimore; Department of Medicine, Stanford University School of Medicine, Stanford, CA (G.A.F.); Providence Cancer Center at Providence Health and Services, Portland, OR (T.S.C.); Department of Medicine, University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, Pittsburgh (J.J.L.); Bon Secours Cancer Institute, Richmond, VA (S.M.D.); Division of Medical Oncology, Ohio State University Comprehensive Cancer Center-James Cancer Center and Solove Research Institute, and Human Cancer Genetics Program, Ohio State University Comprehensive Cancer Center, Columbus (R.M.G., A.C.); and Merck, Kenilworth, NJ, and North Wales, PA (M.K.).

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http://dx.doi.org/10.1056/NEJMoa1500596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481136PMC
June 2015

Immune checkpoint blockade: a common denominator approach to cancer therapy.

Cancer Cell 2015 Apr 6;27(4):450-61. Epub 2015 Apr 6.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center and Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15356108150008
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http://dx.doi.org/10.1016/j.ccell.2015.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400238PMC
April 2015

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.

Sci Transl Med 2015 Apr;7(283):283ra52

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD 21231, USA. Department of Oncology and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa4306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4504692PMC
April 2015

Distinct mechanisms of tumor resistance to NK killing: of mice and men.

Authors:
Drew M Pardoll

Immunity 2015 Apr;42(4):605-6

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5598348PMC
April 2015

PD-L1 expression in melanocytic lesions does not correlate with the BRAF V600E mutation.

Cancer Immunol Res 2015 Feb 4;3(2):110-5. Epub 2014 Nov 4.

Department of Pathology, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland. Department of Dermatology, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Baltimore, Maryland. Department of Oncology, The Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, Baltimore, Maryland.

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http://dx.doi.org/10.1158/2326-6066.CIR-14-0145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324161PMC
February 2015

The Bacteroides fragilis toxin gene is prevalent in the colon mucosa of colorectal cancer patients.

Clin Infect Dis 2015 Jan 9;60(2):208-15. Epub 2014 Oct 9.

Department of Medicine Department of Oncology Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1093/cid/ciu787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351371PMC
January 2015

PD-1, PD-L1, PD-L2 expression in the chordoma microenvironment.

J Neurooncol 2015 01 28;121(2):251-9. Epub 2014 Oct 28.

Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1007/s11060-014-1637-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4322919PMC
January 2015

Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade.

J Immunother Cancer 2014 16;2(1):42. Epub 2014 Dec 16.

Department of Oncology, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD USA ; Ludwig Center for Cancer Genetics and Therapeutics and the Swim Across America Laboratory, Johns Hopkins University School of Medicine and Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD USA.

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http://dx.doi.org/10.1186/s40425-014-0042-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267741PMC
December 2014

Survival, durable tumor remission, and long-term safety in patients with advanced melanoma receiving nivolumab.

J Clin Oncol 2014 Apr 3;32(10):1020-30. Epub 2014 Mar 3.

Suzanne L. Topalian, William H. Sharfman, Julie R. Brahmer, Evan J. Lipson, Janis M. Taube, and Drew M. Pardoll, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD; Mario Sznol and Harriet M. Kluger, Yale University School of Medicine and Smilow Cancer Center, Yale-New Haven Hospital, New Haven, CT; David F. McDermott, Beth Israel Deaconess Medical Center; Donald P. Lawrence, Massachusetts General Hospital Cancer Center; F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA; Richard D. Carvajal, Memorial Sloan-Kettering Cancer Center, New York, NY; Michael B. Atkins, Georgetown-Lombardi Comprehensive Cancer Center, Washington, DC; John D. Powderly, Carolina BioOncology Institute, Huntersville, NC; Philip D. Leming, The Christ Hospital Cancer Center, Cincinnati, OH; Igor Puzanov and Jeffrey A. Sosman, Vanderbilt University Medical Center, Nashville, TN; David C. Smith, University of Michigan, Ann Arbor, MI; and Jon M. Wigginton, Georgia D. Kollia, and Ashok Gupta, Bristol-Myers Squibb, Princeton, NJ.

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http://dx.doi.org/10.1200/JCO.2013.53.0105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811023PMC
April 2014

Immune checkpoint inhibitors: making immunotherapy a reality for the treatment of lung cancer.

Cancer Immunol Res 2013 Aug 22;1(2):85-91. Epub 2013 Jul 22.

Authors' Affiliation: The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland.

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856021PMC
August 2013