Publications by authors named "Dov Freimark"

73Publications

Sex Differences in Clinical Characteristics and 1- and 10-Year Mortality Among Patients Hospitalized With Acute Heart Failure.

Am J Med Sci 2020 Oct 27;360(4):392-401. Epub 2020 May 27.

The Leviev Heart Center, Sheba Medical Center, Tel Hashomer and Sakler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.amjms.2020.05.028DOI Listing
October 2020

Reduction in Filamin C transcript is associated with arrhythmogenic cardiomyopathy in Ashkenazi Jews.

Int J Cardiol 2020 Oct 5;317:133-138. Epub 2020 Apr 5.

Heart Center, Sheba Medical Center, Tel Hashomer, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1016/j.ijcard.2020.04.005DOI Listing
October 2020

Relation of Low Serum Magnesium to Mortality and Cardiac Allograft Vasculopathy Following Heart Transplantation.

Am J Cardiol 2020 05 5;125(10):1517-1523. Epub 2020 Mar 5.

Heart Transplantation Unit, Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, Israel; Sackler School of Medicine, Tel Aviv University, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2020.02.030DOI Listing
May 2020

Hypomagnesemia is associated with new-onset diabetes mellitus following heart transplantation.

Cardiovasc Diabetol 2019 10 11;18(1):132. Epub 2019 Oct 11.

Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1186/s12933-019-0939-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787962PMC
October 2019

Improved long-term outcomes after heart transplantation utilizing donors with a traumatic mode of brain death.

J Cardiothorac Surg 2019 Jul 22;14(1):138. Epub 2019 Jul 22.

Heart Transplantation Unit, Leviev Cardiothoracic and Vascular Center, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.

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http://dx.doi.org/10.1186/s13019-019-0963-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647135PMC
July 2019

Efficacy and safety of exercise rehabilitation in patients with hypertrophic cardiomyopathy.

J Cardiol 2019 Nov 22;74(5):466-472. Epub 2019 Jun 22.

Leviev Heart Institute, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan, and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

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http://dx.doi.org/10.1016/j.jjcc.2019.04.013DOI Listing
November 2019

Differences in Mortality of New-Onset (De-Novo) Acute Heart Failure Versus Acute Decompensated Chronic Heart Failure.

Am J Cardiol 2019 08 25;124(4):554-559. Epub 2019 May 25.

Heart Research Follow-up Program, University of Rochester, Rochester, New York.

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http://dx.doi.org/10.1016/j.amjcard.2019.05.031DOI Listing
August 2019

Does donor-recipient age difference matter in outcome of heart transplantation?

Clin Transplant 2019 07 19;33(7):e13593. Epub 2019 Jun 19.

Leviev Cardiovascular and Thoracic Surgery Center, Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1111/ctr.13593DOI Listing
July 2019

Recurrent acute cellular rejection graded ISHLT 1R early after heart transplantation negatively affects long-term outcomes: The prognostic significance of 1990 ISHLT grades 1B and 2.

Transpl Immunol 2019 08 21;55:101204. Epub 2019 Mar 21.

The Olga and Lev Leviev Heart Center, Sheba Medical Center, Ramat Gan, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1016/j.trim.2019.03.003DOI Listing
August 2019

Ethnic disparity in Israel impacts long-term results after heart transplantation.

Isr J Health Policy Res 2019 Jan 14;8(1). Epub 2019 Jan 14.

The Olga and Lev Leviev Heart Center, Sheba Medical Center Tel Hashomer, Heart Transplantation Unit, Heart Failure Institute, 52621, Ramat Gan, Israel.

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https://ijhpr.biomedcentral.com/articles/10.1186/s13584-018-
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http://dx.doi.org/10.1186/s13584-018-0271-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330742PMC
January 2019

Trends and Outcomes in Heart Transplantation over the Past Three Decades: A Single Tertiary Center Experience in Israel.

Isr Med Assoc J 2018 Sep;20(9):567-572

Heart Transplantation Unit, Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel.

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September 2018

Donor-recipient ethnic mismatching impacts short- and long-term results of heart transplantation.

Clin Transplant 2018 10 27;32(10):e13389. Epub 2018 Sep 27.

The Olga and Lev Leviev Heart Center, Sheba Medical Center, Ramat Gan, Israel.

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http://dx.doi.org/10.1111/ctr.13389DOI Listing
October 2018

Sub-acute vs. Late-onset Presentation of Oncotherapy Related Cardiotoxicity: Predictors of Cardiac Function Recovery and Long-Term Outcome.

Isr Med Assoc J 2018 Aug;20(8):486-490

Leviev Heart Center, Sheba Medical Center, Tel Hashomer, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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August 2018

High tacrolimus trough level variability is associated with rejections after heart transplant.

Am J Transplant 2018 10 13;18(10):2571-2578. Epub 2018 Aug 13.

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1111/ajt.15016DOI Listing
October 2018

Heart Transplantation in a Left Ventricular Assist Device Recipient After Donor's Extracorporeal Membrane Oxygenation Support: Is It Safe?

Transplantation 2018 04;102(4):e185-e186

The Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1097/TP.0000000000002059DOI Listing
April 2018

De novo mitral regurgitation as a cause of heart failure exacerbation in patients with hypertrophic cardiomyopathy.

Int J Cardiol 2018 Feb 21;252:122-127. Epub 2017 Nov 21.

The Leviev Heart Center, Sheba Medical Center, Israel; Tel Aviv University, Israel.

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http://dx.doi.org/10.1016/j.ijcard.2017.11.060DOI Listing
February 2018

CRISPR correction of the PRKAG2 gene mutation in the patient's induced pluripotent stem cell-derived cardiomyocytes eliminates electrophysiological and structural abnormalities.

Heart Rhythm 2018 02 14;15(2):267-276. Epub 2017 Sep 14.

Department of Physiology, Biophysics and Systems Biology, Technion, Haifa, Israel; The Rappaport Institute, Technion, Haifa, Israel; Rappaport Faculty of Medicine, Technion, Haifa, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.09.024DOI Listing
February 2018

Metformin therapy reduces the risk of malignancy after heart transplantation.

J Heart Lung Transplant 2017 Dec 23;36(12):1350-1357. Epub 2017 Jun 23.

The Olga and Lev Leviev Heart Center, Sheba Medical Center, Ramat Gan, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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https://linkinghub.elsevier.com/retrieve/pii/S10532498173187
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http://dx.doi.org/10.1016/j.healun.2017.06.009DOI Listing
December 2017

Feelings of indebtedness and guilt toward donor and immunosuppressive medication adherence among heart transplant (HTx) patients, as assessed in a cross-sectional study with the Basel Assessment of Adherence to Immunosuppressive Medications Scale (BAASIS).

Clin Transplant 2017 Oct 19;31(10). Epub 2017 Aug 19.

Sackler Faculty of Medicine, Stanley Steyer School of Health Professions, Nursing Department, Tel Aviv University, Ramat Aviv, Tel Aviv, Israel.

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http://dx.doi.org/10.1111/ctr.13053DOI Listing
October 2017

Psychiatric and cognitive characteristics of individuals with Danon disease (LAMP2 gene mutation).

Am J Med Genet A 2017 Sep 19;173(9):2461-2466. Epub 2017 Jun 19.

The Behavioral Neurogenetics Center, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1002/ajmg.a.38320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561494PMC
September 2017

The impact of gender mismatching on early and late outcomes following heart transplantation.

ESC Heart Fail 2017 Feb 30;4(1):31-39. Epub 2016 Aug 30.

Heart Failure Institute, Heart Center, Sheba Medical Center and Sackler School of Medicine Tel Aviv University Tel Aviv Israel.

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http://dx.doi.org/10.1002/ehf2.12107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292637PMC
February 2017

Blood pressure dynamics during exercise rehabilitation in heart failure patients.

Eur J Prev Cardiol 2017 05 7;24(8):818-824. Epub 2017 Feb 7.

1 Cardiac Rehabilitation Institute, Leviev Heart Center, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Israel.

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http://dx.doi.org/10.1177/2047487317690951DOI Listing
May 2017

Clinical Experience With Deferiprone Treatment for Friedreich Ataxia.

J Child Neurol 2016 07 29;31(8):1036-40. Epub 2016 Mar 29.

Movement Disorders Institute, Department of Neurology, Sagol Neuroscience Center, Chaim Sheba Medical Center, Tel-Hashomer, Ramat-Gan, Israel Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

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http://dx.doi.org/10.1177/0883073816636087DOI Listing
July 2016

Inflammatory Biomarkers in Refractory Congestive Heart Failure Patients Treated with Peritoneal Dialysis.

Biomed Res Int 2015 11;2015:590851. Epub 2015 Oct 11.

Nephrology and Hypertension Institute, Sheba Medical Center and Sackler Faculty of Medicine, 5265601 Tel-Hashomer, Israel.

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http://dx.doi.org/10.1155/2015/590851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619815PMC
August 2016

Reverse remodeling and the mechanism of mitral regurgitation improvement in patients with dilated cardiomyopathy.

Cardiol J 2015 3;22(4):391-6. Epub 2015 Aug 3.

Leviev Heart Institute, Sheba Medical Center, Sheba, Israel; Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

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http://dx.doi.org/10.5603/CJ.a2015.0022DOI Listing
August 2016

Phenotype and prognostic correlations of the converter region mutations affecting the β myosin heavy chain.

Heart 2015 Jul 2;101(13):1047-53. Epub 2015 May 2.

Health in Code, A Coruña, Spain Inherited Cardiovascular Disease Unit, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas Universidade da Coruña (UDC), A Coruña, Spain.

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http://dx.doi.org/10.1136/heartjnl-2014-307205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484257PMC
July 2015

Predictors and outcome of sustained improvement in left ventricular function in dilated cardiomyopathy.

Clin Cardiol 2014 Nov 18;37(11):687-92. Epub 2014 Sep 18.

Heart Failure Institute and Leviev Heart Center, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1002/clc.22331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649463PMC
November 2014

Titin mutation in familial restrictive cardiomyopathy.

Int J Cardiol 2014 Jan 25;171(1):24-30. Epub 2013 Nov 25.

Heart Failure Service and Heart Institute, Tel Aviv University, Tel Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2013.11.037DOI Listing
January 2014

Efficacy of exercise training in symptomatic patients with hypertrophic cardiomyopathy: results of a structured exercise training program in a cardiac rehabilitation center.

Eur J Prev Cardiol 2015 Jan 8;22(1):13-9. Epub 2013 Aug 8.

Sackler Faculty of Medicine, Tel Aviv University, Israel Heart Failure Service, Sheba Medical Center, Israel.

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http://dx.doi.org/10.1177/2047487313501277DOI Listing
January 2015

Peritoneal dialysis in patients with refractory congestive heart failure: potential prognostic factors.

Blood Purif 2013 24;35(4):285-94. Epub 2013 May 24.

Nephrology and Hypertension Institute, Sheba Medical Center and Sackler Faculty of Medicine, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1159/000351202DOI Listing
March 2014

Predicting prognosis in dilated cardiomyopathy.

Isr Med Assoc J 2012 Nov;14(11):687-9

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November 2012

Tricuspid valve regurgitation after orthotopic heart transplantation: prevalence and etiology.

J Transplant 2012 14;2012:120702. Epub 2012 Oct 14.

Heart Transplantation Unit, Department of Cardiac Surgery, Leviev Heart Center, Sheba Medical Center, and the Sackler Faculty of Medicine, Tel Aviv University, 52621 Ramat Gan, Israel.

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http://dx.doi.org/10.1155/2012/120702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477771PMC
October 2012

A novel titin mutation in adult-onset familial dilated cardiomyopathy.

Am J Cardiol 2012 Jun 3;109(11):1644-50. Epub 2012 Apr 3.

Heart Failure Service and Heart Institute, Sheba Medical Center, Tel Hashomer, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1016/j.amjcard.2012.01.392DOI Listing
June 2012

[Hospice for end-stage heart failure and its relevance to Israel].

Harefuah 2011 Apr;150(4):359-62, 418

Heart Failure Service, Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel.

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April 2011

An advanced chronic heart failure day care service: a 5 year single-center experience.

Isr Med Assoc J 2009 Jul;11(7):419-25

Heart Failure Service, Leviev Heart Center, Sheba Medical Center, Tel Hashomer, Israel.

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July 2009

Vascular endothelial function predicts mortality risk in patients with advanced ischaemic chronic heart failure.

Eur J Heart Fail 2009 Jun 30;11(6):588-93. Epub 2009 Apr 30.

Heart Institute, Chaim Sheba Medical Center, 52621 Tel Hashomer, Israel.

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http://dx.doi.org/10.1093/eurjhf/hfp053DOI Listing
June 2009

Increased glycogen stores due to gamma-AMPK overexpression protects against ischemia and reperfusion damage.

Biochem Pharmacol 2008 Apr 5;75(7):1482-91. Epub 2008 Jan 5.

The Cardiac Research Laboratory, Felsenstein Medical Research Center, Rabin Medical Center, Tel Aviv University, Petah Tikva 49100, Israel.

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http://dx.doi.org/10.1016/j.bcp.2007.12.011DOI Listing
April 2008

[Criteria for the acceptable heart donor: maximizing the use of hearts recovered from potential donors in Israel].

Harefuah 2007 Nov;146(11):894-9, 908

Department of Cardiology, Rabin Medical Center, Campus Beilinson & Shneider, Petah Tikva, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv.

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November 2007

[Ventricular assist devices as bridge to heart transplantation in cardiogenic shock or terminal heart failure--12 years experience at the Sheba Medical Center].

Harefuah 2007 Nov;146(11):833-6, 911

Heart Transplantation Unit, Department of Cardiothoracic Surgery, Sheba Medical Center, Tel Hashomer affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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November 2007

[AMP-activated protein kinase: how a mistake in energy gauge causes glycogen storage].

Harefuah 2007 Oct;146(10):770-5, 813-4

The Cardiac Research Laboratory, Felsenstein Medical Research Center, Rabin Medical Center, Petah Tikva.

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October 2007

Exercise training in advanced heart failure patients: discordance between improved exercise tolerance and unchanged NT-proBNP levels.

Int J Cardiol 2008 May 24;126(1):114-9. Epub 2007 Jul 24.

Heart Failure Service and Heart Institute, Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1016/j.ijcard.2007.05.005DOI Listing
May 2008

Improved exercise tolerance and cardiac function in severe chronic heart failure patients undergoing a supervised exercise program.

Int J Cardiol 2007 Apr 1;116(3):309-14. Epub 2007 Feb 1.

Heart Failure Center, Department of Neurology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1016/j.ijcard.2006.03.021DOI Listing
April 2007

Improvement of congestive heart failure by upgrading of conventional to resynchronization pacemakers.

Pacing Clin Electrophysiol 2006 Aug;29(8):880-4

Heart Institute, Sheba Medical Center, Tel-Hashomer, and Sackler School of Medicine, Tel-Aviv University, Israel.

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http://dx.doi.org/10.1111/j.1540-8159.2006.00455.xDOI Listing
August 2006

Short-term sibutramine therapy is associated with weight loss and improved endothelial function in obese patients with coronary artery disease.

Am J Cardiol 2006 Jun 7;97(11):1650-3. Epub 2006 Apr 7.

Heart Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1016/j.amjcard.2005.12.059DOI Listing
June 2006

The intensive statin therapy myth.

Isr Med Assoc J 2005 Nov;7(11):683-7

Heart Institute, Sheba Medical Center, Tel Hashomer, Israel.

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November 2005

Cognitive functions in severe congestive heart failure before and after an exercise training program.

Int J Cardiol 2005 Aug 12;103(2):145-9. Epub 2005 Jan 12.

Department of Neurology and Neuro-Vascular Laboratory, Sheba Medical Center, Israel.

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http://dx.doi.org/10.1016/j.ijcard.2004.08.044DOI Listing
August 2005

Genetic ideology of dilated cardiompathy.

Isr Med Assoc J 2005 Jun;7(6):392-6

Heart Failure Clinic, Heart Institute, Sheba Medical Center, Tel Hashomer, Israel.

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June 2005

Hemodynamics during humoral rejection events with total versus standard orthotopic heart transplantation.

Ann Thorac Cardiovasc Surg 2004 Oct;10(5):285-9

Department of Thoracic and Cardiovascular Surgery, University Essen, Essen, Germany.

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http://www.atcs.jp/pdf/2004_10_5/285.pdf
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October 2004

Ischemic preconditioning: nearly two decades of research. A comprehensive review.

Atherosclerosis 2004 Feb;172(2):201-10

Cardiac Rehabilitation Institute and Heart Failure Unit, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

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http://linkinghub.elsevier.com/retrieve/pii/S002191500300238
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http://dx.doi.org/10.1016/S0021-9150(03)00238-7DOI Listing
February 2004

Functional class in patients with heart failure is associated with the development of diabetes.

Am J Med 2003 Mar;114(4):271-5

Cardiac Rehabilitation Institute, Neufeld Cardiac Research Institute, the Chaim Sheba Medical Center, Tel-Hashomer, 52621 Israel.

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http://dx.doi.org/10.1016/s0002-9343(02)01530-9DOI Listing
March 2003

Oscillations in peripheral arterial tone in congestive heart failure patients: a new marker for Cheyne-Stokes breathing.

Cardiology 2002 ;98(1-2):21-4

Cardiac Institute, Heart Failure Clinic, The Chaim Sheba Medical Center, and Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel.

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https://www.karger.com/Article/FullText/64676
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http://dx.doi.org/10.1159/000064676DOI Listing
January 2003

Mechanism of mitral regurgitation in inferior wall acute myocardial infarction.

Am J Cardiol 2002 Aug;90(3):306-9

Heart Institute, Chaim Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1016/s0002-9149(02)02469-4DOI Listing
August 2002

Effects of platelet membrane glycoprotein polymorphisms on the risk of myocardial infarction in young males.

Isr Med Assoc J 2002 Jun;4(6):411-4

Institute of Thrombosis and Hemostasis, Sheba Medical Center, Tel Hashomer, Israel.

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June 2002

The incidence, pathophysiology, treatment and prognosis of Cheyne-Stokes breathing disorder in patients with congestive heart failure.

Herz 2002 Mar;27(2):107-12

Cardiac Rehabilitation Institute and Heart Failure Unit, Sheba Medical Center, Tel Hashomer, Israel.

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http://dx.doi.org/10.1007/s00059-002-2350-2DOI Listing
March 2002

Timing of aspirin administration as a determinant of survival of patients with acute myocardial infarction treated with thrombolysis.

Am J Cardiol 2002 Feb;89(4):381-5

The Heart Institute, Sheba Medical Center, Tel-Aviv University, Tel-Hashomer, Israel.

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http://dx.doi.org/10.1016/s0002-9149(01)02256-1DOI Listing
February 2002