Douglas Yee

Douglas Yee

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Douglas Yee

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Insulin Receptor Substrate Suppression by the Tyrphostin NT157 Inhibits Responses to Insulin-Like Growth Factor-I and Insulin in Breast Cancer Cells.

Horm Cancer 2018 12 18;9(6):371-382. Epub 2018 Sep 18.

Department of Pharmacology, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1007/s12672-018-0343-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434949PMC
December 2018

Breast cancer survival predicted by TP53 mutation status differs markedly depending on treatment.

Breast Cancer Res 2018 10 1;20(1):115. Epub 2018 Oct 1.

Department of Biochemistry and Molecular Biology, Tulane School of Medicine, 1430 Tulane Avenue, mail code 8543, New Orleans, LA, 70112, USA.

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https://breast-cancer-research.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s13058-018-1044-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167800PMC
October 2018

Anti-insulin-like growth factor therapy in breast cancer.

Authors:
Douglas Yee

J Mol Endocrinol 2018 07 29;61(1):T61-T68. Epub 2018 Jan 29.

Masonic Cancer CenterUniversity of Minnesota, Minneapolis, Minnesota, USA

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http://dx.doi.org/10.1530/JME-17-0261DOI Listing
July 2018

Mechanisms of Resistance to Neoadjuvant Chemotherapy in Breast Cancer.

N Engl J Med 2017 12;377(23):2287-2289

From the University of Pennsylvania, Philadelphia (A.D.); the University of Minnesota, Minneapolis (D.Y.); and the University of California, San Francisco, San Francisco (L.E.).

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http://dx.doi.org/10.1056/NEJMcibr1711545DOI Listing
December 2017

Vascular function in breast cancer survivors on aromatase inhibitors: a pilot study.

Breast Cancer Res Treat 2017 Nov 11;166(2):541-547. Epub 2017 Aug 11.

Division of Cardiology, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1007/s10549-017-4447-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632072PMC
November 2017

Mobile Phone Multilevel and Multimedia Messaging Intervention for Breast Cancer Screening: Pilot Randomized Controlled Trial.

JMIR Mhealth Uhealth 2017 Nov 7;5(11):e154. Epub 2017 Nov 7.

Division of Hematology, Oncology and Transplantation, School of Medicine and Pharmacology, University of Minnesota, Twin Cities, Minneapolis, MN, United States.

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http://dx.doi.org/10.2196/mhealth.7091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698632PMC
November 2017

Targeting Insulin Receptor in Breast Cancer Using Small Engineered Protein Scaffolds.

Mol Cancer Ther 2017 07 3;16(7):1324-1334. Epub 2017 May 3.

Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518922PMC
July 2017

Revisiting the IGF-1R as a breast cancer target.

NPJ Precis Oncol 2017 1;1. Epub 2017 May 1.

Masonic Cancer Center, University of Minnesota, MMC 806, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1038/s41698-017-0017-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687252PMC
May 2017

Cu-Labeled Gp2 Domain for PET Imaging of Epidermal Growth Factor Receptor.

Mol Pharm 2016 11 10;13(11):3747-3755. Epub 2016 Oct 10.

Department of Chemical Engineering and Materials Science, ‡Department of Pharmacology, §Department of Medicine, and ∥Masonic Cancer Center, University of Minnesota-Twin Cities , 421 16th Avenue SE, Minneapolis, Minnesota 55455, United States.

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http://dx.doi.org/10.1021/acs.molpharmaceut.6b00538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5519506PMC
November 2016

The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.

Sci Adv 2016 Oct 7;2(10):e1601737. Epub 2016 Oct 7.

Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN 55455, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN 55455, USA.; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1126/sciadv.1601737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055383PMC
October 2016

EMT reversal in human cancer cells after IR knockdown in hyperinsulinemic mice.

Endocr Relat Cancer 2016 09 19;23(9):747-58. Epub 2016 Jul 19.

Division of EndocrinologyDiabetes and Bone Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA

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http://dx.doi.org/10.1530/ERC-16-0142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4990486PMC
September 2016

Adaptive Randomization of Neratinib in Early Breast Cancer.

N Engl J Med 2016 Jul;375(1):11-22

From University of California, San Francisco (J.W.P., C.Y., L.J.V., N.M.H., M.B.B., A.J.C., M.M., J.L., S.E.D., G.L.H., L.J.E.), and QuantumLeap Healthcare Collaborative (M.P.), San Francisco, Buck Institute for Research and Aging, Novato (C.Y.), University of California, Davis, Davis (M.H.), University of California, San Diego, San Diego (A.M.W., R.S., T.H.), and University of Southern California, Los Angeles (D.T.) - all in California; Georgetown Lombardi Comprehensive Cancer Center, Washington, DC (M.C.L., C.I.); University of Minnesota, Minneapolis (D.Y., T.C.H.), and Mayo Clinic, Rochester (J.C.B.) - both in Minnesota; M.D. Anderson Cancer Center, Houston (W.F.S., L.P., S.L.M., D.A.B.), University of Texas Southwestern Medical Center, Dallas (D.M.E., B.B.H.), and Berry Consultants, Austin (A.S., D.A.B.) - all in Texas; Gemini Group, Ann Arbor, MI (J.P.); University of Pennsylvania, Philadelphia (A.D.); Oregon Health and Sciences University, Portland (S.Y.C., K.A.K.); Swedish Medical Center, Seattle (H.G.K.); University of Chicago (R.N.) and Loyola University (K.S.A.) - both in Chicago; Inova Fairfax Hospital, Falls Church, VA (K.K.E.); University of Denver, Denver (A.D.E.); Mayo Clinic, Scottsdale (D.W.N.), and University of Arizona, Tucson (J.E.L., R.K.V.) - both in Arizona; University of Kansas, Lawrence (Q.J.K.); and Emory University, Atlanta (W.C.W.).

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http://dx.doi.org/10.1056/NEJMoa1513750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259558PMC
July 2016

Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer.

N Engl J Med 2016 Jul;375(1):23-34

From University of California, San Francisco (UCSF) (H.S.R., C.Y., L.J.V., M.B.B., N.M.H., A.J.C., C.E., J.L., S.E.D., G.L.H., L.J.E.), and QuantumLeap Healthcare Collaborative (M.P.), San Francisco, Buck Institute for Research and Aging, Novato (C.Y.), University of California, Davis, Davis (M.H.), University of California San Diego, San Diego (A.M.W., R.S.), and University of Southern California, Los Angeles (D.T.) - all in California; University of Chicago (O.I.O., R.N.), and Loyola University (K.S.A.), Chicago; University of Pennsylvania, Philadelphia (A.D.); Gemini Group, Ann Arbor, MI (J.P.); University of Texas M.D. Anderson Cancer Center, Houston (W.F.S., L.P., S.L.M., D.A.B.), UT Southwestern Medical Center, Dallas (D.M.E., B.B.H.), and Berry Consultants, Austin (A.S., D.A.B.) - all in Texas; University of Minnesota, Minneapolis (D.Y.), and Mayo Clinic, Rochester (J.C.B., T.C.H.) - both in Minnesota; Swedish Medical Center, Seattle (H.G.K.); Georgetown Lombardi Comprehensive Cancer Center, Washington, DC (M.C.L., C.I.); University of Kansas, Lawrence (Q.J.K.); University of Arizona, Tucson (J.E.L., R.K.V.), and Mayo Clinic, Scottsdale (D.W.N.) - both in Arizona; Oregon Health and Sciences University, Portland (S.Y.C., K.A.K.); University of Denver, Denver (A.D.E.); Inova Fairfax Hospital, Falls Church, VA (K.K.E.); and Emory University, Atlanta (W.C.W.).

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http://dx.doi.org/10.1056/NEJMoa1513749DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5259561PMC
July 2016

Utility of high-sensitivity cardiac troponin T in patients receiving anthracycline chemotherapy.

Vasc Health Risk Manag 2015 24;11:591-4. Epub 2015 Nov 24.

Division of Cardiology, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.2147/VHRM.S89842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664531PMC
May 2016

IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.

PLoS One 2015 14;10(7):e0133152. Epub 2015 Jul 14.

Department of Pediatrics, Division of Hematology, Oncology and Stem Cell Transplantation, New York Medical College, Valhalla, NY, United States of America; Department of Microbiology and Immunology, New York Medical College, Valhalla, NY, United States of America; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, NY, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133152PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501840PMC
April 2016

Amplified in Breast Cancer Regulates Transcription and Translation in Breast Cancer Cells.

Neoplasia 2016 Feb;18(2):100-10

Masonic Cancer Center, Departments of Medicine and Pharmacology, University of Minnesota, Minneapolis, MN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2016.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5005264PMC
February 2016

Neoadjuvant as Future for Drug Development in Breast Cancer--Response.

Clin Cancer Res 2016 Jan;22(1):269

University of California, San Francisco, San Francisco, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-1643DOI Listing
January 2016

Minireview: Were the IGF Signaling Inhibitors All Bad?

Mol Endocrinol 2015 Nov 14;29(11):1549-57. Epub 2015 Sep 14.

Departments of Medicine (H.B., D.Y.) and Pharmacology (D.Y.) and Masonic Cancer Center (D.Y.), University of Minnesota, Minneapolis, Minnesota 55455.

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http://dx.doi.org/10.1210/me.2015-1157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414672PMC
November 2015

Altered regulation of PDK4 expression promotes antiestrogen resistance in human breast cancer cells.

Springerplus 2015 10;4:689. Epub 2015 Nov 10.

Department of Biomedical Sciences, University of Minnesota Medical School, Duluth Campus, Duluth, MN USA ; Masonic Cancer Center, University of Minnesota, Minneapolis, MN USA.

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http://dx.doi.org/10.1186/s40064-015-1444-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641142PMC
November 2015

Longitudinal FDG-PET Revealed Regional Functional Heterogeneity of Bone Marrow, Site-Dependent Response to Treatment and Correlation with Hematological Parameters.

J Cancer 2015 15;6(6):531-7. Epub 2015 Apr 15.

1. Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA ; 4. Department of Therapeutic Radiology, Medical School, University of Minnesota, Minneapolis, MN, USA.

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http://www.jcancer.org/v06p0531.htm
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http://dx.doi.org/10.7150/jca.11348DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439938PMC
May 2015

Validation of marrow fat assessment using noninvasive imaging with histologic examination of human bone samples.

Bone 2015 Mar 12;72:118-22. Epub 2014 Nov 12.

Department of Therapeutic Radiology, University of Minnesota, Minneapolis, MN, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S87563282140040
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http://dx.doi.org/10.1016/j.bone.2014.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282942PMC
March 2015

A tale of two receptors: insulin and insulin-like growth factor signaling in cancer.

Authors:
Douglas Yee

Clin Cancer Res 2015 Feb 10;21(4):667-9. Epub 2014 Oct 10.

Department of Medicine, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota

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http://clincancerres.aacrjournals.org/cgi/doi/10.1158/1078-0
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http://dx.doi.org/10.1158/1078-0432.CCR-14-2056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498265PMC
February 2015

CCR 20th Anniversary commentary: stayin' alive-antiapoptotic proteins and breast cancer.

Authors:
Douglas Yee

Clin Cancer Res 2015 Feb;21(4):665-6

Masonic Cancer Center, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-2548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333724PMC
February 2015

Spatial and temporal fracture pattern in breast and gynecologic cancer survivors.

J Cancer 2015 1;6(1):66-9. Epub 2015 Jan 1.

2. Masonic Cancer Center, University of Minnesota, Minneapolis; ; 3. Department of Obstetrics and Gynecology, University of Minnesota, Minneapolis;

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http://dx.doi.org/10.7150/jca.10288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278916PMC
January 2015

Insulin-like growth factors, insulin, and growth hormone signaling in breast cancer: implications for targeted therapy.

Endocr Pract 2014 Nov;20(11):1214-21

Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota Department of Medicine, University of Minnesota, Minneapolis, Minnesota Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota.

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http://journals.aace.com/doi/abs/10.4158/EP14208.RA
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http://dx.doi.org/10.4158/EP14208.RADOI Listing
November 2014

Chemotherapy and targeted therapy for women with human epidermal growth factor receptor 2-negative (or unknown) advanced breast cancer: American Society of Clinical Oncology Clinical Practice Guideline.

J Clin Oncol 2014 Oct 2;32(29):3307-29. Epub 2014 Sep 2.

Ann H. Partridge, Dana-Farber Cancer Institute; Steven E. Come, Beth Israel Deaconess Medical Center; Beverly Moy, Massachusetts General Hospital, Boston, MA; R. Bryan Rumble, American Society of Clinical Oncology, Alexandria; Michael A. Danso, Virginia Oncology Associates, Norfolk, VA; Lisa A. Carey, University of North Carolina, Chapel Hill, NC; Nancy E. Davidson, University of Pittsburgh Cancer Institute/University of Pittsburgh Medical Center, Pittsburgh, PA; Angelo Di Leo, Sandro Pitigliani Medical Oncology Unit, Prato, Italy; Julie Gralow, University of Washington/Seattle Cancer Care Alliance, Seattle, WA; Gabriel N. Hortobagyi, The University of Texas MD Anderson Cancer Center, Houston, TX; Douglas Yee, University of Minnesota/Masonic Cancer Center, Minneapolis, MN; Shelley B. Brundage, Patient Representative, Washington, DC; Maggie Wilcox, Independent Cancer Patients' Voice; and Ian E. Smith, Royal Marsden Hospital, London, United Kingdom.

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http://ascopubs.org/doi/10.1200/JCO.2014.56.7479
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http://dx.doi.org/10.1200/JCO.2014.56.7479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6076042PMC
October 2014

IGF-I regulates redox status in breast cancer cells by activating the amino acid transport molecule xC-.

Cancer Res 2014 Apr 31;74(8):2295-305. Epub 2014 Mar 31.

Authors' Affiliations: Masonic Cancer Center; and Departments of Pharmacology and Medicine, University of Minnesota, Minneapolis, Minnesota.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006361PMC
April 2014

Yin Yang gene expression ratio signature for lung cancer prognosis.

PLoS One 2013 17;8(7):e68742. Epub 2013 Jul 17.

Manitoba Institute of Cell Biology, University of Manitoba, Winnipeg, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0068742PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3714286PMC
March 2014

Water-fat MRI for assessing changes in bone marrow composition due to radiation and chemotherapy in gynecologic cancer patients.

J Magn Reson Imaging 2013 Dec 28;38(6):1578-84. Epub 2013 Feb 28.

Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota, Minneapolis, Minnesota, USA.

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http://dx.doi.org/10.1002/jmri.24071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690168PMC
December 2013

Fulvestrant regulates epidermal growth factor (EGF) family ligands to activate EGF receptor (EGFR) signaling in breast cancer cells.

Breast Cancer Res Treat 2013 Jun 18;139(2):351-60. Epub 2013 May 18.

Department of Medicine, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1007/s10549-013-2541-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711713PMC
June 2013

The influence of therapeutic radiation on the patterns of bone remodeling in ovary-intact and ovariectomized mice.

Calcif Tissue Int 2013 Apr 12;92(4):372-84. Epub 2013 Jan 12.

Department of Therapeutic Radiology, University of Minnesota, 420 Delaware Street SE, Mayo Mail Code 494, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1007/s00223-012-9688-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3595353PMC
April 2013

The influence of therapeutic radiation on the patterns of bone marrow in ovary-intact and ovariectomized mice.

PLoS One 2012 6;7(8):e42668. Epub 2012 Aug 6.

Department of Therapeutic Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042668PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3412808PMC
January 2013

Targeting insulin and insulin-like growth factor signaling in breast cancer.

J Mammary Gland Biol Neoplasia 2012 Dec 10;17(3-4):251-61. Epub 2012 Oct 10.

Department of Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.

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http://link.springer.com/10.1007/s10911-012-9268-y
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http://dx.doi.org/10.1007/s10911-012-9268-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3534944PMC
December 2012

Acquired resistance to tamoxifen is associated with loss of the type I insulin-like growth factor receptor: implications for breast cancer treatment.

Cancer Res 2012 Jul 9;72(13):3372-80. Epub 2012 May 9.

Masonic Cancer Center, and Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-0684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520534PMC
July 2012

Insulin-like growth factor receptor inhibitors: baby or the bathwater?

Authors:
Douglas Yee

J Natl Cancer Inst 2012 Jul 3;104(13):975-81. Epub 2012 Jul 3.

Masonic Cancer Center, University of Minnesota420 Delaware Street SE, Minneapolis, MN, USA.

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http://dx.doi.org/10.1093/jnci/djs258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634550PMC
July 2012

Enhancement of doxorubicin cytotoxicity of human cancer cells by tyrosine kinase inhibition of insulin receptor and type I IGF receptor.

Breast Cancer Res Treat 2012 May 18;133(1):117-26. Epub 2011 Aug 18.

Masonic Cancer Center, University of Minnesota, MMC 806, 420 Delaware St SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1007/s10549-011-1713-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523065PMC
May 2012

Estrogen-related receptor alpha: an orphan finds a family.

Breast Cancer Res 2012 May 10;14(3):309. Epub 2012 May 10.

Masonic Cancer Center, Departments of Medicine and Pharmacology, University of Minnesota, MMC 806, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1186/bcr3124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446323PMC
May 2012

Pharmacodynamic modeling of sequence-dependent antitumor activity of insulin-like growth factor blockade and gemcitabine.

AAPS J 2012 Mar 19;14(1):1-9. Epub 2011 Nov 19.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, 55455, USA.

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http://dx.doi.org/10.1208/s12248-011-9308-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3291184PMC
March 2012

Should diabetic women with breast cancer have their own intervention studies?

Endocr Relat Cancer 2012 Feb 13;19(1):C13-7. Epub 2012 Feb 13.

Division of Hematology, Oncology and Transplantation, Masonic Cancer Center, University of Minnesota, 420 Delaware Street SouthEast, MMC 480, Minneapolis, Minnesota 55455-0392, USA.

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http://dx.doi.org/10.1530/ERC-11-0309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680369PMC
February 2012

Skeletal remodeling following clinically relevant radiation-induced bone damage treated with zoledronic acid.

Calcif Tissue Int 2012 Jan 15;90(1):40-9. Epub 2011 Nov 15.

Department of Therapeutic Radiology, University of Minnesota, 420 Delaware Street SE, Mayo Mail Code 494, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1007/s00223-011-9547-4DOI Listing
January 2012

Killing the second messenger: targeting loss of cell cycle control in endocrine-resistant breast cancer.

Endocr Relat Cancer 2011 Aug 4;18(4):C19-24. Epub 2011 Jul 4.

Departments of Medicine and Pharmacology, Masonic Cancer Center, University of Minnesota, 420 Delaware Street South East, MMC 806, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1530/ERC-11-0112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924782PMC
August 2011

Exogenous near-infrared fluorophores and their applications in cancer diagnosis: biological and clinical perspectives.

Expert Opin Med Diagn 2011 May;5(3):241-51

Department of Medicine, Masonic Cancer Center, MMC 806, 420 Delaware St SE, Minneapolis, MN, 55455, USA, .

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090156PMC
May 2011

Targeting IGF-1R: at a crossroad.

Oncology (Williston Park) 2011 May;25(6):535-6; discussion 551

Department of Pharmacology and Chemical Biology, University of Pittsburg Cancer Institute, Magee Womens Research Institute, Pittsburgh, Pennsylvania, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925073PMC
May 2011

The IGF pathway regulates ERα through a S6K1-dependent mechanism in breast cancer cells.

Mol Endocrinol 2011 Mar 3;25(3):516-28. Epub 2011 Feb 3.

Department of Pharmacology, Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://dx.doi.org/10.1210/me.2010-0373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045742PMC
March 2011

Diabetes and cancer: a consensus report.

CA Cancer J Clin 2010 Jul-Aug;60(4):207-21. Epub 2010 Jun 16.

Departments of Nutrition and Epidemiology, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.3322/caac.20078DOI Listing
August 2010

Angiotensin converting enzyme inhibitors may be protective against cardiac complications following anthracycline chemotherapy.

Breast Cancer Res Treat 2010 Jul 8;122(2):585-90. Epub 2010 Jan 8.

Department of Medicine, Division of Hematology/Oncology/Transplantation, University of Minnesota, 420 Delaware Street, S.E., MMC 480, Minneapolis, MN 55455, USA.

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http://link.springer.com/10.1007/s10549-009-0730-5
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http://dx.doi.org/10.1007/s10549-009-0730-5DOI Listing
July 2010

Diabetes and cancer: a consensus report.

Diabetes Care 2010 Jul;33(7):1674-85

Department of Nutrition, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.2337/dc10-0666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890380PMC
July 2010

How to train your biomarker.

Authors:
Douglas Yee

Clin Cancer Res 2010 Jun 8;16(12):3091-3. Epub 2010 Jun 8.

Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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June 2010

Adaptor proteins as targets for cancer prevention.

Authors:
Douglas Yee

Cancer Prev Res (Phila) 2010 Mar 23;3(3):263-5. Epub 2010 Feb 23.

Departments of Medicine and Pharmacology, Masonic Cancer Center, University of Minnesota, 420 Delaware Street Southeast, Minneapolis, MN 55455, USA.

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March 2010

Targeting the insulin-like growth factor receptor.

Authors:
Douglas Yee

Clin Adv Hematol Oncol 2009 Jul;7(7):452-4

Division of Hematology, Oncology, and Transplantation, Women's Cancer Program, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.

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July 2009

Sequencing of type I insulin-like growth factor receptor inhibition affects chemotherapy response in vitro and in vivo.

Clin Cancer Res 2009 Apr 7;15(8):2840-9. Epub 2009 Apr 7.

Department of Pharmacology and Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2720270PMC
April 2009

Detection and downregulation of type I IGF receptor expression by antibody-conjugated quantum dots in breast cancer cells.

Breast Cancer Res Treat 2009 Mar 17;114(2):277-85. Epub 2008 Apr 17.

University of Minnesota Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

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March 2009

Metabolite quantification and high-field MRS in breast cancer.

NMR Biomed 2009 Jan;22(1):65-76

Center for Magnetic Resonance Research, Department of Radiology, University of Minnesota Cancer Center, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628417PMC
January 2009

Crosstalk between IGF1R and estrogen receptor signaling in breast cancer.

J Mammary Gland Biol Neoplasia 2008 Dec 12;13(4):423-9. Epub 2008 Nov 12.

Department of Pharmacology, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.

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December 2008

The IGF system in mammary development and breast cancer. Preface.

J Mammary Gland Biol Neoplasia 2008 Dec;13(4):351-2

Department of Pharmacology, Department of Medicine and Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.

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December 2008

Progesterone and breast cancer.

Womens Health (Lond) 2008 Mar;4(2):151-62

University of Minnesota, Cancer Center, Department of Medicine (Hematology, Oncology & Transplantation), 420 Delaware Street SE, MMC 806, MN 55455, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038907PMC
March 2008

Pharmacodynamic characterization of gemcitabine cytotoxicity in an in vitro cell culture bioreactor system.

Cancer Chemother Pharmacol 2008 Feb 12;61(2):291-9. Epub 2007 Apr 12.

Department of Experimental and Clinical Pharmacology, College of Pharmacy and Comprehensive Cancer Center, University of Minnesota, 308 Harvard St SE, Minneapolis, MN 55455, USA.

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February 2008

Quantum dots for cancer diagnosis and therapy: biological and clinical perspectives.

Nanomedicine (Lond) 2008 Feb;3(1):83-91

University of Minnesota Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.

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February 2008

Hawai'i's role to increase public participation in health research.

Hawaii Med J 2008 Jan;67(1):4-6

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January 2008

Insulin-like growth factors and breast cancer therapy.

Adv Exp Med Biol 2007 ;608:101-12

Department of Pharmacology, University of Minnesota Cancer Center, Minneapolis, MN 55455, USA.

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December 2007

Short versus continuous gemcitabine treatment of non-small cell lung cancer in an in vitro cell culture bioreactor system.

Lung Cancer 2007 Nov 25;58(2):196-204. Epub 2007 Jul 25.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1016/j.lungcan.2007.06.005DOI Listing
November 2007

Insulin-like growth factor (IGF)-I controls prostate fibromuscular development: IGF-I inhibition prevents both fibromuscular and glandular development in eugonadal mice.

Endocrinology 2007 Mar 30;148(3):1080-8. Epub 2006 Nov 30.

The Bunnie Joan Sachs Laboratory, Neuroendocrine Unit, Department of Medicine, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA.

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March 2007

Down-regulation of type I insulin-like growth factor receptor increases sensitivity of breast cancer cells to insulin.

Cancer Res 2007 Jan;67(1):391-7

University of Minnesota Cancer Center, 420 Delaware Street Southeast, Minneapolis, MN 55455, USA

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January 2007

Disrupting insulin-like growth factor signaling as a potential cancer therapy.

Mol Cancer Ther 2007 Jan;6(1):1-12

University of Minnesota Cancer Center, MMC 806, 420 Delaware Street Southeast, Minneapolis, MN 55455, USA.

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January 2007

Is the type I insulin-like growth factor receptor a therapeutic target in endometrial cancer?

Clin Cancer Res 2006 Nov;12(21):6323-5

University of Minnesota Cancer Center, Minneapolis, Minnesota 55455, USA.

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November 2006

Effects of insulin-like growth factor-1 receptor inhibition in mesothelioma. Thoracic Surgery Directors Association Resident Research Award.

Ann Thorac Surg 2006 Sep;82(3):996-1001; discussion 1001-2

Department of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

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September 2006

Randomized controlled trial of weight training and lymphedema in breast cancer survivors.

J Clin Oncol 2006 Jun 15;24(18):2765-72. Epub 2006 May 15.

Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.

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June 2006

Effects of weight training on quality of life in recent breast cancer survivors: the Weight Training for Breast Cancer Survivors (WTBS) study.

Cancer 2006 May;106(9):2076-83

Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.

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May 2006

Characterization of an in vitro cell culture bioreactor system to evaluate anti-neoplastic drug regimens.

Breast Cancer Res Treat 2006 Apr;96(3):217-25

Department of Experimental and Clinical Pharmacology, College of Pharmacy and Comprehensive Cancer Center, University of Minnesota, Minneapolis 55455, USA.

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April 2006

Naloxone acts as an antagonist of estrogen receptor activity in MCF-7 cells.

Mol Cancer Ther 2006 Mar;5(3):611-20

Division of Hematology, Oncology and Transplantation, University of Minnesota Medical School, 420 Delaware Street Southeast, Minneapolis, MN 55455, USA.

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March 2006

Targeting the insulin-like growth factor axis as a cancer therapy.

Future Oncol 2006 Feb;2(1):101-10

Department of Medicine, Hematology, Oncology and Transplantation, University of Minnesota Cancer Center, MMC 806, 420 Delaware Street SE, Minneapolis, MN 55455, USA.

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February 2006

Inhibitors of insulin-like growth factor signaling: a therapeutic approach for breast cancer.

J Mammary Gland Biol Neoplasia 2006 Jan;11(1):27-39

Department of Medicine and Cancer Center, University of Minnesota, Mayo Mail Code 806, 420 Delaware St, SE, Minneapolis, MN 55455, USA.

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January 2006

Type I insulin-like growth factor receptor as a therapeutic target in cancer.

Cancer Res 2005 Nov;65(22):10123-7

Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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November 2005

Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration.

Breast Cancer Res Treat 2005 Sep;93(2):159-68

Department of Medicine, University of Minnesota Cancer Center, Minneapolis, MN, 55455, USA.

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September 2005

Safety and efficacy of weight training in recent breast cancer survivors to alter body composition, insulin, and insulin-like growth factor axis proteins.

Cancer Epidemiol Biomarkers Prev 2005 Jul;14(7):1672-80

Division of Clinical Epidemiology University of Pennsylvania 423 Guardian Drive, 9th floor Blockley Drive, Philadelphia, PA 19072 215-898-0901

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http://cebp.aacrjournals.org/cgi/doi/10.1158/1055-9965.EPI-0
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July 2005