Douglas S Hawkins

Douglas S Hawkins

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Douglas S Hawkins

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Thyroid Cancer in the Pediatric Population.

Genes (Basel) 2019 09 18;10(9). Epub 2019 Sep 18.

University of Washington Medical Center, Fred Hutchinson Cancer Research Center and Cancer and Blood Disorders Center, Seattle Children's Hospital, MB.8.501, Seattle, WA 98105, USA.

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http://dx.doi.org/10.3390/genes10090723DOI Listing
September 2019

Risk-based treatment for patients with first relapse or progression of rhabdomyosarcoma: A report from the Children's Oncology Group.

Cancer 2019 Aug 8;125(15):2602-2609. Epub 2019 May 8.

Department of Pediatrics, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1002/cncr.32122DOI Listing
August 2019

Infantile NTRK-associated Mesenchymal Tumors.

Pediatr Dev Pathol 2018 Jan-Feb;21(1):68-78. Epub 2017 Jul 6.

2 Department of Pathology, Seattle Children's Hospital, Seattle, Washington.

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http://journals.sagepub.com/doi/10.1177/1093526617712639
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http://dx.doi.org/10.1177/1093526617712639DOI Listing
May 2019

Larotrectinib for the treatment of TRK fusion solid tumors.

Expert Rev Anticancer Ther 2019 Jan 24;19(1):1-10. Epub 2018 Oct 24.

b Seattle Children's Hospital , University of Washington, Fred Hutchinson Cancer Research Center , Seattle , WA , USA.

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https://www.tandfonline.com/doi/full/10.1080/14737140.2019.1
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http://dx.doi.org/10.1080/14737140.2019.1538796DOI Listing
January 2019

Rhabdomyosarcoma.

Nat Rev Dis Primers 2019 01 7;5(1). Epub 2019 Jan 7.

Seattle Children's Hospital, University of Washington, and Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41572-018-0051-2DOI Listing
January 2019

Demographic and Treatment Variables Influencing Outcome for Localized Paratesticular Rhabdomyosarcoma: Results From a Pooled Analysis of North American and European Cooperative Groups.

J Clin Oncol 2018 Oct 23:JCO2018789388. Epub 2018 Oct 23.

David O. Walterhouse, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Donald A. Barkauskas, University of Southern California, Los Angeles; David Hall, Children's Oncology Group, Monrovia, CA; Andrea Ferrari, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale Tumori, Milan; Gian Luca De Salvo, Istituto Oncologico Veneto Istituto di Ricovero e Cura a Carattere Scientifico, Padua; Gianni Bisogno, University of Padua, Padova, Italy; Ewa Koscielniak, Olgahospital, Stuttgart; Guido Seitz, University Hospital, Marburg, Germany; Michael C.G. Stevens, Royal Hospital for Children, Bristol, United Kingdom; Hélène Martelli, Assistance Publique-Hôpitaux de Paris, Hopital Bicetre, Le Kremlin-Bicetre; Christophe Bergeron, Centre Léon Bérard, Lyon; Veronique Minard-Colin, Gustave Roussy, Villejuif, France; David A. Rodeberg, East Carolina University, Greenville, NC; Margarett Shnorhavorian and Douglas S. Hawkins, Seattle Children's Hospital, University of Washington; Douglas S. Hawkins, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA; Roshni Dasgupta and John C. Breneman, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; James R. Anderson, Merck Research Laboratories, North Wales, PA; and William H. Meyer, University of Oklahoma School of Medicine, Oklahoma City, OK.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.9388
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http://dx.doi.org/10.1200/JCO.2018.78.9388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286163PMC
October 2018

Addition of Vincristine and Irinotecan to Vincristine, Dactinomycin, and Cyclophosphamide Does Not Improve Outcome for Intermediate-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.

J Clin Oncol 2018 09 9;36(27):2770-2777. Epub 2018 Aug 9.

Douglas S. Hawkins, Erin R. Rudzinski, and Margarett Shnorhavorian, Seattle Children's Hospital, Seattle, WA; Yueh-Yun Chi and Jing Tian, University of Florida, Gainesville, FL; James R. Anderson, Merck Research Laboratories, North Wales, PA; Carola A.S. Arndt, Mayo Clinic, Rochester, MN; Lisa Bomgaars, Texas Children's Hospital; Andrea Hayes-Jordan, MD Anderson Cancer Center, Houston; Stephen X. Skapek, University of Texas Southwestern, Dallas, TX; Sarah S. Donaldson, Lynn Million, and Sheri L. Spunt, Stanford University School of Medicine, Stanford; Leo Mascarenhas and David M. Parham, Children's Hospital of Los Angeles, Los Angeles; Jeannine S. McCune, City of Hope, Duarte, CA; Mary Beth McCarville, St Jude Children's Research Hospital, Memphis, TN; Geoff McCowage, Children's Hospital at Westmead, Westmead, New South Wales, Australia; Carol D. Morris, Johns Hopkins University, Baltimore, MD, David A. Rodeberg, East Carolina University, Greenville, NC; Lisa A. Teot, Boston Children's Hospital; Torunn I. Yock, Massachusetts General Hospital, Boston, MA; Suzanne Wolden, Memorial Sloan Kettering Cancer Center, New York, NY; and William H. Meyer, University of Oklahoma Health Sciences Center, Oklahoma City, OK.

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http://dx.doi.org/10.1200/JCO.2018.77.9694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145831PMC
September 2018

High-Dose Chemotherapy and Blood Autologous Stem-Cell Rescue Compared With Standard Chemotherapy in Localized High-Risk Ewing Sarcoma: Results of Euro-E.W.I.N.G.99 and Ewing-2008.

J Clin Oncol 2018 Sep 6:JCO2018782516. Epub 2018 Sep 6.

Jeremy Whelan, University College Hospital; Ian Judson, Institute of Cancer Research, London; Bernadette Brennan, Royal Manchester Children's Hospital, Manchester; Bruce Morland, Birmingham Children's Hospital; Keith Wheatley, University of Birmingham, Birmingham; Ian Lewis, Leeds Community Healthcare National Health Service Trust, Leeds; Alan Craft, Newcastle University, Newcastle upon Tyne, United Kingdom; Marie-Cecile Le Deley and Cyril Lervat, Centre Oscar Lambret, Lille; Gwénaël Le Teuff, Nathalie Gaspar, and Odile Oberlin, Institut Gustave Roussy, Villejuif; Jean-Yves Blay, Centre Léon Bérard; Perrine Marec-Berard, Institute of Pediatric Onco-Haematology, Lyon; Marie-Pierre Castex, Centre Hospitalier Universitaire de Toulouse, Toulouse; Jean-Claude Gentet, Centre Hospitalier Universitaire La Timone, Marseille; Marta Jimenez, Unicancer; Valerie Laurence and Jean Michon, Institut Curie, Paris; France; Uta Dirksen, Sebastian Bauer, Andreas Ranft, University Hospital Essen, Essen; Susanne Amler, Institut für Biometrie und Klinische Forschung; Wolfgang Hartmann and Heribert Juergens, Universitätsklinikum, Münster, Münster; Stefan Bielack, Klinikum Stuttgart, Stuttgart; Stefan Burdach, Comprehensive Cancer Center, München; Dagmar Dilloo, University-Clinic Bonn, Bonn; Angelika Eggert, Charité University; Peter Reichardt, HELIOS Klinikum Berlin-Buch, Berlin; Wolf-Achim Hassenpflug, University Medical Center Hamburg-Eppendorf, Hamburg; Thomas Klingebiel, Childrens University Hospital, Frankfurt; Udo Kontny, University Medical Center Aachen, Aachen; Michael Paulussen, Children's and Adolescents' Hospital, Datteln; Germany; Douglas S. Hawkins, Seattle Children's Hospital, Seattle, WA; Hans Gelderblom, Leiden University Medical Center, Leiden; Hendrik van den Berg, University of Amsterdam, Amsterdam, the Netherlands; Lars Hjorth, Skane University Hospital, Lund, Sweden; Jarmila Kruseova, Faculty Hospital Motol Prague, Prague, Czech Republic; Ruth Ladenstein, St Anna Children's Hospital and Children's Cancer Research Institute, Vienna, Austria; Sandrine Marreaud, European Organisation for Research and Treatment of Cancer, Brussels, Belgium.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.2516
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http://dx.doi.org/10.1200/JCO.2018.78.2516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209090PMC
September 2018

Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes.

Cell Rep 2018 07;24(1):238-251

Department of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Gill Center for Cancer and Blood Disorders, Children's Health, Children's Medical Center, Dallas, TX. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.006DOI Listing
July 2018

Efficacy of Larotrectinib in TRK Fusion-Positive Cancers in Adults and Children.

N Engl J Med 2018 02;378(8):731-739

From Memorial Sloan Kettering Cancer Center (A. Drilon, J.F.H., R.B., M.L., D.M.H.) and Weill Cornell Medical College (A. Drilon, D.M.H.), New York; University of Texas Southwestern Medical Center-Children's Health, Dallas (T.W.L.); Stanford Cancer Center, Stanford University, Palo Alto (S.K.), Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California (L.M.), and UCLA David Geffen School of Medicine (N.F.), Los Angeles, and Loxo Oncology, South San Francisco (B.B.T., K.E., S.C., N.C.K., M.C.C.) - all in California; Dana-Farber-Boston Children's Cancer and Blood Disorders Center (S.G.D.), Dana-Farber Cancer Institute (G.D.D., M.N.), Ludwig Center at Harvard (G.D.D.), and Massachusetts General Hospital (A.F.F.) - all in Boston; the Finsen Center, Rigshospitalet, Copenhagen (U.N.L.); University of Colorado, Aurora (R.C.D.); St. Jude Children's Research Hospital, Memphis (A.S.P.), and Vanderbilt University, Nashville (J.B.) - both in Tennessee; Cincinnati Children's Hospital Medical Center, Cincinnati (B.T.); University Hospitals of Cleveland Medical Center (A. Dowlati) and Taussig Cancer Institute, Cleveland Clinic (D.P.S.S.), Cleveland; University of Pennsylvania Perelman School of Medicine, Department of Otorhinolaryngology and Head and Neck Surgery, and the Abramson Cancer Center (M.S.B.), and Fox Chase Cancer Center (W.S.E.-D.), Philadelphia; University of Washington-Seattle Cancer Care Alliance (C.B.), Seattle Children's Hospital (E.R.R.), and Seattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Research Center (D.S. Hawkins), Seattle; University of Texas M.D. Anderson Cancer Center, Houston (F.M.-B., D.S. Hong); Inova Schar Cancer Institute, Falls Church, VA (J.D.); START Madrid, Centro Integral Oncológico Clara Campal, Madrid (V.B.); Nemours Children's Hospital, Orlando (R.N.), and Memorial Cancer Institute-Florida International University, Miami (L.E.R.) - both in Florida; Oregon Health and Science University, Portland (M.T.); and WVU Cancer Institute, West Virginia University, Morgantown (P.C.M.).

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http://dx.doi.org/10.1056/NEJMoa1714448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857389PMC
February 2018

Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.

Pediatr Blood Cancer 2017 Dec 18;64(12). Epub 2017 May 18.

Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1002/pbc.26645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647228PMC
December 2017

Patterns of PD-1, PD-L1, and PD-L2 expression in pediatric solid tumors.

Pediatr Blood Cancer 2017 Nov 10;64(11). Epub 2017 May 10.

Department of Laboratories, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington.

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http://doi.wiley.com/10.1002/pbc.26613
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http://dx.doi.org/10.1002/pbc.26613DOI Listing
November 2017

Clinical and Genetic Risk Prediction of Subsequent CNS Tumors in Survivors of Childhood Cancer: A Report From the COG ALTE03N1 Study.

J Clin Oncol 2017 Nov 4;35(32):3688-3696. Epub 2017 Oct 4.

Xuexia Wang, University of North Texas, Denton, TX; Can-Lan Sun, City of Hope, Duarte; Leo Mascarenhas, Children's Hospital Los Angeles, University of Southern California, Los Angeles; Doojduen Villaluna, Children's Oncology Group, Monrovia, CA; Lindsey Hageman, Kandice Smith, Purnima Singh, Wendy Landier, and Smita Bhatia, University of Alabama at Birmingham, Birmingham, AL; Sunil Desai, University of Alberta, Edmonton, Alberta, Canada; Douglas S. Hawkins, Seattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Research Center, Seattle, WA; Melissa M. Hudson and Leslie L. Robison, St Jude Children's Research Hospital, Memphis, TN; Joseph P. Neglia, University of Minnesota Medical School, Minneapolis, MN; Kevin C. Oeffinger, Duke University Medical Center, Durham, NC; and A. Kim Ritchey, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://ascopubs.org/doi/10.1200/JCO.2017.74.7444
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http://dx.doi.org/10.1200/JCO.2017.74.7444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678343PMC
November 2017

CD49b inhibits osteogenic differentiation and plays an important role in osteosarcoma progression.

Oncotarget 2017 Oct 23;8(50):87848-87859. Epub 2017 Sep 23.

Department of Pediatrics, Children's Cancer Hospital, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.18632/oncotarget.21254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675677PMC
October 2017

Patterns of chemotherapy-induced toxicities and outcome in children and adolescents with metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.

Pediatr Blood Cancer 2017 Sep 23;64(9). Epub 2017 Mar 23.

Division of Hematology/Oncology, Department of Pediatrics, Seattle Children's Hospital, University of Washington, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.1002/pbc.26479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567865PMC
September 2017

Vaginal Ewing Sarcoma: An Uncommon Clinical Entity in Pediatric Patients.

J Clin Imaging Sci 2017 25;7:17. Epub 2017 Apr 25.

Department of Radiology, Seattle Children's Hospital, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.4103/jcis.JCIS_96_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433652PMC
April 2017

Outcome of Patients With Recurrent Osteosarcoma Enrolled in Seven Phase II Trials Through Children's Cancer Group, Pediatric Oncology Group, and Children's Oncology Group: Learning From the Past to Move Forward.

J Clin Oncol 2016 09 11;34(25):3031-8. Epub 2016 Jul 11.

Joanne P. Lagmay, Shands Hospital for Children, University of Florida, Gainesville, FL; Mark D. Krailo and Ha Dang, University of Southern California, Los Angeles; and Children's Oncology Group, Monrovia; Theodore Zwerdling, Jonathan Jaques Children's Cancer Center, Miller Children's and Women's Hospital, Long Beach, CA; AeRang Kim, Center for Cancer and Blood Disorders, Children's National Medical Center, Washington, DC; Douglas S. Hawkins, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA; Orren Beaty III, Zeiss Children's Cancer Center, Mission Hospitals, Asheville, NC; Brigitte C. Widemann, National Institutes of Health Clinical Center, Bethesda, MD; Lisa Bomgaars and Susan M. Blaney, Baylor College of Medicine/Texas Children's Cancer Center, Houston; Anne-Marie Langevin, University of Texas Health Science Center at San Antonio, San Antonio, TX; Holcombe E. Grier and Katherine A. Janeway, Dana-Farber Cancer Institute, Boston Children's Cancer and Blood Disorders Center, Boston, MA; Brenda Weigel, University of Minnesota, Minneapolis, MN; and Richard Gorlick, The Albert Einstein College of Medicine of Yeshiva University, The Children's Hospital at Montefiore, New York, NY.

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http://dx.doi.org/10.1200/JCO.2015.65.5381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012712PMC
September 2016

Opportunities for Improvement in Pathology Reporting of Childhood Nonrhabdomyosarcoma Soft Tissue Sarcomas:  A Report From Children's Oncology Group (COG) Study ARST0332.

Am J Clin Pathol 2016 Sep 10;146(3):328-38. Epub 2016 Aug 10.

Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA.

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http://dx.doi.org/10.1093/ajcp/aqw114DOI Listing
September 2016

Potential pitfalls of mass spectrometry to uncover mutations in childhood soft tissue sarcoma: A report from the Children's Oncology Group.

Sci Rep 2016 09 19;6:33429. Epub 2016 Sep 19.

Department of Pediatrics Division of Hematology/Oncology, and the Harold C. Simmons Cancer Center, University of Texas Southwestern Medical Center, and the Pauline Allen Gill Center for Cancer and Blood Disorders, Children's Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1038/srep33429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027578PMC
September 2016

Histology, Fusion Status, and Outcome in Alveolar Rhabdomyosarcoma With Low-Risk Clinical Features: A Report From the Children's Oncology Group.

Pediatr Blood Cancer 2016 Apr 12;63(4):634-9. Epub 2016 Jan 12.

Division of Hematology, Oncology, and Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1002/pbc.25862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755849PMC
April 2016

Factors Associated With Mortality in Pediatric vs Adult Nasopharyngeal Carcinoma.

JAMA Otolaryngol Head Neck Surg 2016 Mar;142(3):217-22

Department of Otolaryngology-Head and Neck Surgery, University of Washington, Seattle.

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http://dx.doi.org/10.1001/jamaoto.2015.3217DOI Listing
March 2016

Second Malignant Neoplasms in Rhabdomyosarcoma: Victims of Our Own Success or an Underlying Genetic Predisposition Syndrome?

Pediatr Blood Cancer 2016 Feb 27;63(2):189-90. Epub 2015 Oct 27.

Department of Pediatrics, Seattle Children's Hospital, Seattle, Washington.

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http://dx.doi.org/10.1002/pbc.25776DOI Listing
February 2016

Intensive Multiagent Therapy, Including Dose-Compressed Cycles of Ifosfamide/Etoposide and Vincristine/Doxorubicin/Cyclophosphamide, Irinotecan, and Radiation, in Patients With High-Risk Rhabdomyosarcoma: A Report From the Children's Oncology Group.

J Clin Oncol 2016 Jan 26;34(2):117-22. Epub 2015 Oct 26.

Brenda J. Weigel, University of Minnesota, Minneapolis; Carola A.S. Arndt, Mayo Clinic, Rochester, MN; Elizabeth Lyden, Nebraska Medical Center, Omaha, NE; James R. Anderson, Frontier Science and Technology Research Foundation, Madison, WI; William H. Meyer, University of Oklahoma Health Sciences Center, Oklahoma City, OK; David M. Parham, Children's Hospital of Los Angeles, Los Angeles, CA; David A. Rodeberg, East Carolina University, Greenville, NC; Jeff M. Michalski, Washington University School of Medicine, St Louis, MO; and Douglas S. Hawkins, University of Washington, Seattle, WA.

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http://jco.ascopubs.org/content/early/2015/10/23/JCO.2015.63
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.63.4048
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http://dx.doi.org/10.1200/JCO.2015.63.4048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070550PMC
January 2016

The World Health Organization Classification of Skeletal Muscle Tumors in Pediatric Rhabdomyosarcoma: A Report From the Children's Oncology Group.

Arch Pathol Lab Med 2015 Oct 19;139(10):1281-7. Epub 2015 May 19.

From the Department of Laboratories, Seattle Children's Hospital, Seattle, Washington (Dr Rudzinski); Frontier Science & Technology Research Foundation, Inc, Madison, Wisconsin (Dr Anderson); the University of Washington School of Medicine and Fred Hutchinson Cancer Research Center and Cancer and Blood Disorders Center at Seattle Children's Hospital, Seattle (Dr Hawkins); the Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas (Dr Skapek); the Department of Pathology, Children's Hospital of Los Angeles, Los Angeles, California (Dr Parham); and the Department of Pathology, Boston Children's Hospital, Boston, Massachusetts (Dr Teot).

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http://dx.doi.org/10.5858/arpa.2014-0475-OADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651658PMC
October 2015

Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group.

Clin Cancer Res 2015 Oct;21(20):4733-9

Pauline Allen Gill Center for Cancer and Blood Disorders, Children's Medical Center, Dallas, Texas. Department of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-3326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4610152PMC
October 2015

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration.

J Clin Oncol 2015 Sep 24;33(27):3036-46. Epub 2015 Aug 24.

Nathalie Gaspar, Marie-Cecile Le Deley, and Odile Oberlin, Institut Gustave Roussy, Villejuif; Nathalie Gaspar, Marie-Cecile Le Deley, Line Claude, Olivier Delattre, Jean Michon, Perrine Marec-Bérard, and Odile Oberlin, Société Française de Lutte Contre les Cancers et les Leucémies de l'Enfant et de l'Adolescent; Marie-Cecile Le Deley, Paris-Sud University, Le Kremlin-Bicêtre; Line Claude and Perrine Marec-Bérard, Centre Léon-Bérard, Lyon; Olivier Delattre and Jean Michon, Institut Curie, Paris, France; Douglas S. Hawkins, Seattle Children's Hospital, Seattle, WA; Douglas S. Hawkins, Mark L. Bernstein, and Richard B. Womer, Children's Oncology Group; Uta Dirksen and Heribert Juergens, University Hospital Münster, Münster; Uta Dirksen, Michael Paulussen, and Heribert Juergens, Gesellschaft für Pädiatrische Onkologie und Hämatologie; Michael Paulussen, Children's and Adolescents' Hospital, Witten/Herdecke University, Datteln, Germany; Ian J. Lewis, Alder Hey Children's National Health Service (NHS) Foundation Trust, Liverpool; Ian J. Lewis, Robert Grimer, Bernadette Brennan, and Alan W. Craft, Children's Cancer and Leukaemia Group; Robert Grimer, Royal Orthopaedic Hospital, Birmingham; Jeremy Whelan, University College London Hospital NHS Foundation Trust; Ian Judson, Royal Marsden Hospital, London; Bernadette Brennan, Royal Manchester Children's Hospital, Manchester; Alan W. Craft, Royal Victoria Infirmary, Newcastle, United Kingdom; Stefano Ferrari and Piero Picci, Rizzoli Institute, Bologna; Stefano Ferrari, Piero Picci, Roberto Luksch, Italian Sarcoma Group; Roberto Luksch, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Istituto Nazionale dei Tumori, Milan, Italy; Heinrich Kovar and Ruth Ladenstein, Children's Cancer Institute, St Anna Kinderkrebsforschung, Wien; Heinrich Kovar and Ruth Ladenstein, Arbeitsgemeinschaft Ambulant Tätiger Pädiatrischer Onkologen und Hämatologen, Vienna, Austria; Jeremy Whelan and Ian Judson, European O

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http://jco.ascopubs.org/content/33/27/3036.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.59.5256
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http://dx.doi.org/10.1200/JCO.2014.59.5256DOI Listing
September 2015

MRI and CT of Low-Grade Fibromyxoid Sarcoma in Children: A Report From Children's Oncology Group Study ARST0332.

AJR Am J Roentgenol 2015 Aug;205(2):414-20

7 Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, TN.

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http://dx.doi.org/10.2214/AJR.14.13972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570741PMC
August 2015

Clonality and evolutionary history of rhabdomyosarcoma.

PLoS Genet 2015 Mar 13;11(3):e1005075. Epub 2015 Mar 13.

Genetics Branch, Oncogenomics Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Pediatric Oncology Branch, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4358975PMC
March 2015

Assessing the scale of tumor heterogeneity by complete hierarchical segmentation of MRI.

Phys Med Biol 2015 Feb 9;60(3):977-93. Epub 2015 Jan 9.

Department of Radiation Oncology, University of Washington Medical Center, 1959 NE Pacific St. Box 356043, Seattle, WA 98115, USA.

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http://dx.doi.org/10.1088/0031-9155/60/3/977DOI Listing
February 2015

Ganglioside GD2 expression is maintained upon recurrence in patients with osteosarcoma.

Clin Sarcoma Res 2015 24;5(1). Epub 2015 Jan 24.

Division of Pediatric Hematology/Oncology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, 3415 Bainbridge Ave, Rosenthal Pavilion, Room 300, Bronx, NY 10467 USA ; Department of Pediatrics and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY USA.

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http://dx.doi.org/10.1186/s13569-014-0020-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311500PMC
February 2015

Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group.

J Clin Oncol 2014 Nov 29;32(31):3547-52. Epub 2014 Sep 29.

David O. Walterhouse, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, IL; Alberto S. Pappo, Saint Jude Children's Research Hospital, Memphis, TN; Jane L. Meza, James R. Anderson, University of Nebraska Medical Center College of Public Health, Omaha, NE; John C. Breneman, Children's Hospital Medical Center, Cincinnati; Timothy P. Cripe, Nationwide Children's Hospital, Columbus, OH; Andrea Hayes-Jordan, MD Anderson Cancer Center, Houston, TX; David M. Parham, William H. Meyer, University of Oklahoma School of Medicine, Oklahoma City, OK; Douglas S. Hawkins, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1200/JCO.2014.55.6787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209105PMC
November 2014

Maternal and birth characteristics and childhood rhabdomyosarcoma: a report from the Children's Oncology Group.

Cancer Causes Control 2014 Jul 16;25(7):905-13. Epub 2014 May 16.

Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA,

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http://dx.doi.org/10.1007/s10552-014-0390-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091713PMC
July 2014

Cost minimization analysis of two treatment regimens for low-risk rhabdomyosarcoma in children: a report from the Children's Oncology Group.

Pediatr Blood Cancer 2014 Jun 22;61(6):970-6. Epub 2014 Jan 22.

Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas; University of Texas School of Public Health, Division of Management, Policy and Community Health, Houston, Texas.

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http://dx.doi.org/10.1002/pbc.24950DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4370185PMC
June 2014

Myogenin, AP2β, NOS-1, and HMGA2 are surrogate markers of fusion status in rhabdomyosarcoma: a report from the soft tissue sarcoma committee of the children's oncology group.

Am J Surg Pathol 2014 May;38(5):654-9

*Department of Laboratories, Seattle Children's Hospital #Hematology/Oncology Division, Fred Hutchinson Cancer Research Center and University of Washington, Seattle, WA †Department of Biostatistics ‡Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE §Center for Cancer Research, National Cancer Institute, Bethesda, MD ∥Departments of Pathology and Pediatrics, The Ohio State University College of Medicine, Columbus, OH ¶Department Pediatrics Hematology-Oncology, University of Texas Southwestern Medical Center, Dallas, TX **Department of Pathology, Children's Hospital of Boston, Boston, MA ††Department of Pathology, The University of Oklahoma Health Sciences Center, Oklahoma City, OK.

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http://dx.doi.org/10.1097/PAS.0000000000000195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010390PMC
May 2014

Early response as assessed by anatomic imaging does not predict failure-free survival among patients with Group III rhabdomyosarcoma: a report from the Children's Oncology Group.

Eur J Cancer 2014 Mar 18;50(4):816-23. Epub 2013 Dec 18.

Seattle Children's Hospital, Seattle, WA, United States; Fred Hutchinson Cancer Research Center, Seattle, WA, United States; University of Washington, Seattle, WA, United States.

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http://dx.doi.org/10.1016/j.ejca.2013.11.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944684PMC
March 2014

What is new in the biology and treatment of pediatric rhabdomyosarcoma?

Curr Opin Pediatr 2014 Feb;26(1):50-6

aDepartment of Pediatrics, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington School of Medicine, Seattle, Washington bDivision of Hematology/Oncology, Hospital for Sick Children, University of Toronto, Toronto, Canada cDepartment of Pathology, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington, USA.

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http://dx.doi.org/10.1097/MOP.0000000000000041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096484PMC
February 2014

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.

Cancer Discov 2014 Feb 23;4(2):216-31. Epub 2014 Jan 23.

1Pediatric Oncology Branch, Oncogenomics Section, Center for Cancer Research, NIH; 2Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland; 3Broad Institute of MIT and Harvard, Cambridge; 4Medical Oncology and Center for Cancer Genome Discovery, Dana-Farber Cancer Institute; 5Department of Pathology, Harvard Medical School, Boston, Massachusetts; 6University of Nebraska Medical Center, Omaha, Nebraska; 7Department of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas; and 8Department of Pediatrics, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington; 9The Tumour Bank, The Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, New South Wales, Australia; 10Department of Oncology, Hospital Sant Joan de Deu de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4462130PMC
February 2014

Sarcoma mid-therapy [F-18]fluorodeoxyglucose positron emission tomography (FDG PET) and patient outcome.

J Bone Joint Surg Am 2014 Jan;96(2):152-8

School of Mathematical Sciences, University College Cork, Western Gateway Building, Western Road, Cork, Ireland. E-mail address for J. O'Sullivan: E-mail address for F. O'Sullivan:

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http://dx.doi.org/10.2106/JBJS.M.00062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903137PMC
January 2014

PAX-FOXO1 fusion status drives unfavorable outcome for children with rhabdomyosarcoma: a children's oncology group report.

Pediatr Blood Cancer 2013 Sep 22;60(9):1411-7. Epub 2013 Mar 22.

Children's Medical Center and University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1002/pbc.24532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646073PMC
September 2013

A novel algorithm for simplification of complex gene classifiers in cancer.

Cancer Res 2013 Sep 2;73(18):5625-32. Epub 2013 Aug 2.

Authors' Affiliations: Division of Hematology/Oncology, Department of Pediatrics, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, Texas; Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma; Department of Pathology, University of Southern California and Children's Hospital of Los Angeles, Los Angeles, California; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital and Department of Pathology and Pediatrics, The Ohio State University, Columbus, Ohio; National Cancer Institute, Bethesda, Maryland; Division of Hematology/Oncology, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Washington; Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska; The Section of Pediatric Hematology/Oncology, Department of Pediatrics, Department of Pathology, Center for Research Informatics, and The Computation Institute, University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233649PMC
September 2013

Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: a report from the Children's Oncology Group Soft Tissue Sarcoma Committee.

J Clin Oncol 2013 Sep 12;31(26):3226-32. Epub 2013 Aug 12.

The Soft Tissue Sarcoma Committee of the Children's Oncology Group, Monrovia, CA; Aaron R. Weiss, Maine Medical Center, Portland, ME; Elizabeth R. Lyden and James R. Anderson, University of Nebraska Medical Center, Omaha, NE; Douglas S. Hawkins, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, WA; Sheri L. Spunt, St. Jude Children's Research Hospital and the University of Tennessee Health Science Center, Memphis, TN; David O. Walterhouse, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Suzanne L. Wolden, Memorial Sloan-Kettering Cancer Center, New York, NY; David M. Parham, University of Oklahoma Health Sciences Center, Oklahoma City, OK; David A. Rodeberg, Children's Hospital of Pittsburgh, Pittsburgh, PA; Simon C. Kao, University of Iowa Hospitals and Clinics, Iowa City, IA; and Richard B. Womer, The Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2012.44.6476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757291PMC
September 2013

An evaluation of [F-18]-fluorodeoxy-D-glucose positron emission tomography, bone scan, and bone marrow aspiration/biopsy as staging investigations in Ewing sarcoma.

Pediatr Blood Cancer 2013 Jul 28;60(7):1113-7. Epub 2012 Nov 28.

Office of Academic Affairs, University of Washington School of Medicine, Seattle, Washington 98195-6340, USA.

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http://dx.doi.org/10.1002/pbc.24406DOI Listing
July 2013

Safety and efficacy of high-dose tamoxifen and sulindac for desmoid tumor in children: results of a Children's Oncology Group (COG) phase II study.

Pediatr Blood Cancer 2013 Jul 31;60(7):1108-12. Epub 2012 Dec 31.

Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1002/pbc.24457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646066PMC
July 2013

Children's Oncology Group's 2013 blueprint for research: Soft tissue sarcomas.

Pediatr Blood Cancer 2013 Jun 19;60(6):1001-8. Epub 2012 Dec 19.

Seattle Children's Hospital, University of Washington, and Fred Hutchinson Cancer Research Center, Seattle, WA 98015, USA.

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http://dx.doi.org/10.1002/pbc.24435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777409PMC
June 2013

(18)F-FDG PET in sarcoma treatment response imaging.

Am J Nucl Med Mol Imaging 2011 23;1(1):47-53. Epub 2011 Jun 23.

University of Washington, Departments of Radiology, Orthopedics, and Pathology; Seattle Children's Hospital, Division of Oncology Seattle, WA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477719PMC
November 2012

18F-FDG microPET imaging detects early transient response to an IGF1R inhibitor in genetically engineered rhabdomyosarcoma models.

Pediatr Blood Cancer 2012 Sep 11;59(3):485-92. Epub 2012 Jan 11.

Greehey Children's Cancer Research Institute, University of Texas Health Science Center, San Antonio, Texas, USA.

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http://dx.doi.org/10.1002/pbc.24075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924883PMC
September 2012

Rhabdomyosarcoma: review of the Children's Oncology Group (COG) Soft-Tissue Sarcoma Committee experience and rationale for current COG studies.

Pediatr Blood Cancer 2012 Jul 29;59(1):5-10. Epub 2012 Feb 29.

Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239-3098, USA.

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http://dx.doi.org/10.1002/pbc.24118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008325PMC
July 2012

The inconvenience of convenience cohorts: rhabdomyosarcoma and the PAX-FOXO1 biomarker.

Cancer Epidemiol Biomarkers Prev 2012 Jul 7;21(7):1012-8. Epub 2012 May 7.

Division of Pediatric Hematology/Oncology, Seattle Children's Hospital, Seattle, WA 98105, USA.

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http://dx.doi.org/10.1158/1055-9965.EPI-12-0207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392538PMC
July 2012

The clinical, research, and social value of autopsy after any cancer death: a perspective from the Children's Oncology Group Soft Tissue Sarcoma Committee.

Cancer 2012 Jun 17;118(12):3002-9. Epub 2011 Oct 17.

Department of Oncology, St Jude Children's Research Hospital, University of Tennessee Health Science Center, Memphis, Tennessee 38105-3678, USA.

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http://dx.doi.org/10.1002/cncr.26620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274663PMC
June 2012

Local control with reduced-dose radiotherapy for low-risk rhabdomyosarcoma: a report from the Children's Oncology Group D9602 study.

Int J Radiat Oncol Biol Phys 2012 Jun 19;83(2):720-6. Epub 2011 Nov 19.

Department of Radiation Oncology, University of Cincinnati and Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45219-0757,

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http://dx.doi.org/10.1016/j.ijrobp.2011.06.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305826PMC
June 2012

Ewing sarcoma/primitive neuroectodermal tumor arising from the adrenal gland in an adolescent.

Pediatr Blood Cancer 2011 Oct 16;57(4):691-2. Epub 2011 Jun 16.

Division of General and Thoracic Surgery, Seattle Children's Hospital and University of Washington, Seattle, Washington 98105, USA.

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http://dx.doi.org/10.1002/pbc.23034DOI Listing
October 2011

Sarcomas gone bad: what to do about recurrent Ewing sarcoma.

Pediatr Blood Cancer 2011 Oct 16;57(4):535-6. Epub 2011 Jun 16.

Seattle Children's Hospital, Mailstop: B6553, 4800 Sand Point Way, Seattle, Washington 98105, USA.

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http://dx.doi.org/10.1002/pbc.23126DOI Listing
October 2011

Rhabdomyosarcoma in infants younger than 1 year: a report from the Children's Oncology Group.

Cancer 2011 Aug 24;117(15):3493-501. Epub 2011 Jan 24.

Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239-3098, USA.

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http://dx.doi.org/10.1002/cncr.25887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140625PMC
August 2011

Minimal residual disease detected prior to hematopoietic cell transplantation.

Pediatr Blood Cancer 2011 Jul 2;57(1):163-5. Epub 2011 Mar 2.

Department of Pediatric Hematology/Oncology, Texas Children's Cancer Center/Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1002/pbc.23079DOI Listing
July 2011