Douglas R Langbehn

Douglas R Langbehn

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Douglas R Langbehn

Douglas R Langbehn

Publications by authors named "Douglas R Langbehn"

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Abnormal brain development in child and adolescent carriers of mutant huntingtin.

Neurology 2019 Sep 1;93(10):e1021-e1030. Epub 2019 Aug 1.

From the Department of Psychiatry (E.v.d.P., T.R.K.), University of Iowa Hospitals & Clinics; and the Departments of Psychiatry (D.R.L., A.T., E.A.E., P.C.N.), Biostatistics (D.R.L., A.T.), and Radiology (V.A.M.) and Stead Family Department of Pediatrics (A.L.C.), University of Iowa, Iowa City.

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http://dx.doi.org/10.1212/WNL.0000000000008066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745731PMC
September 2019

Association Between Age and Familial Risk for Alcoholism on Functional Connectivity in Adolescence.

J Am Acad Child Adolesc Psychiatry 2019 Jul 14;58(7):692-701. Epub 2019 Feb 14.

University of Iowa, Iowa City.

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http://dx.doi.org/10.1016/j.jaac.2018.12.008DOI Listing
July 2019

Personality traits and negative consequences associated with binge drinking and marijuana use in college students.

Am J Drug Alcohol Abuse 2019 1;45(4):400-409. Epub 2019 May 1.

a Psychiatry Department , University of Iowa Carver College of Medicine.

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http://dx.doi.org/10.1080/00952990.2019.1601200DOI Listing
May 2019

Cortical Thickness in Adolescents with a Family History of Alcohol Use Disorder.

Alcohol Clin Exp Res 2018 Jan 6;42(1):89-99. Epub 2017 Dec 6.

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa.

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http://dx.doi.org/10.1111/acer.13543DOI Listing
January 2018

Motor, cognitive, and functional declines contribute to a single progressive factor in early HD.

Neurology 2017 Dec 15;89(24):2495-2502. Epub 2017 Nov 15.

From F. Hoffman-La Roche, Ltd (S.A.S., G.P., O.S.K., D.T., J.J.S.), Roche Innovation Center, Basel, Switzerland; University of Rochester (P.A., S.M., E.R.D., K.D.K.), NY; University of Iowa (J.D.L., D.R.L.), Iowa City; Massachusetts General Hospital and Harvard Medical School (M.C., S.H.), Boston; CHDI Management/Foundation (C.S.), Princeton, NJ; University of British Columbia, Vancouver, Canada (B.R.L.); and University College London (S.J.T.), UK.

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http://dx.doi.org/10.1212/WNL.0000000000004743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729794PMC
December 2017

Survival End Points for Huntington Disease Trials Prior to a Motor Diagnosis.

JAMA Neurol 2017 11;74(11):1352-1360

Huntington's Disease Centre, Department of Neurodegenerative Disease, Institute of Neurology, University College London, Queen Square, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2017.2107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710578PMC
November 2017

Polyunsaturated fatty acid composition and childhood adversity: Independent correlates of depressive symptom persistence.

Psychiatry Res 2017 10 21;256:305-311. Epub 2017 Jun 21.

Department of Psychiatry and Pediatrics, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2017.06.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193447PMC
October 2017

Validation of a prognostic index for Huntington's disease.

Mov Disord 2017 02 28;32(2):256-263. Epub 2016 Nov 28.

CHDI Management/CHDI Foundation, Princeton, New Jersey, USA.

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http://dx.doi.org/10.1002/mds.26838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318276PMC
February 2017

Neuropsychiatry and White Matter Microstructure in Huntington's Disease.

J Huntingtons Dis 2015 ;4(3):239-49

Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester and Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.3233/JHD-150160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684097PMC
July 2016

Criteria for success in safety and tolerability trials.

Lancet Neurol 2015 Jan 14;14(1):24-5. Epub 2014 Nov 14.

Department of Psychiatry, Carver College of Medicine, Iowa City, IA, USA; Department of Biostatistics (secondary), College of Public Health, University of Iowa, Iowa City, IA, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(14)70265-0DOI Listing
January 2015

Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease.

J Probab Stat 2012 Jan;2012

Department of Biostatistics, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1155/2012/375935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589804PMC
January 2012

Effects of continuity of care and patient dispositional factors on the physician-patient relationship.

Ann Clin Psychiatry 2011 Aug;23(3):180-5

Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920260PMC
August 2011

Early atrophy of pallidum and accumbens nucleus in Huntington's disease.

J Neurol 2011 Mar 9;258(3):412-20. Epub 2010 Oct 9.

Department of Neurology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00415-010-5768-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112014PMC
March 2011

Cerebral cortex structure in prodromal Huntington disease.

Neurobiol Dis 2010 Dec 2;40(3):544-54. Epub 2010 Aug 2.

Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.nbd.2010.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955824PMC
December 2010

Earliest functional declines in Huntington disease.

Psychiatry Res 2010 Jul 15;178(2):414-8. Epub 2010 May 15.

Department of Psychiatry, The University of Iowa, Iowa City, IA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016517811000189
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http://dx.doi.org/10.1016/j.psychres.2010.04.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629818PMC
July 2010

Self-paced timing detects and tracks change in prodromal Huntington disease.

Neuropsychology 2010 Jul;24(4):435-42

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1037/a0018905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900808PMC
July 2010

Hypochondriacal symptoms associated with a less therapeutic physician-patient relationship.

Psychiatry 2010 ;73(1):57-69

Department of Psychiatry, College of Medicine, College of Public Health at the University of Iowa, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1521/psyc.2010.73.1.57DOI Listing
June 2010

CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches.

Am J Med Genet B Neuropsychiatr Genet 2010 Mar;153B(2):397-408

Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1002/ajmg.b.30992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048807PMC
March 2010

Randomized controlled trial of atomoxetine for cognitive dysfunction in early Huntington disease.

J Clin Psychopharmacol 2009 Oct;29(5):484-7

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1097/JCP.0b013e3181b2ac0aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806326PMC
October 2009

Normative data on and psychometric properties of Verbal and Visual Indexes of the RBANS in older adults.

Clin Neuropsychol 2009 Jan 12;23(1):39-50. Epub 2008 Mar 12.

University of Iowa, Department of Psychiatry, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1080/13854040701861391DOI Listing
January 2009

Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study.

Biol Psychiatry 2007 Dec 3;62(12):1341-6. Epub 2007 May 3.

Department of Psychiatry, University of Iowa, Iowa City, Iowa 52242-1000, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.11.034DOI Listing
December 2007

Social function in boys with cleft lip and palate: relationship to ventral frontal cortex morphology.

Behav Brain Res 2007 Aug 22;181(2):224-31. Epub 2007 Apr 22.

University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.bbr.2007.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976412PMC
August 2007

Abnormal brain structure in children with isolated clefts of the lip or palate.

Arch Pediatr Adolesc Med 2007 Aug;161(8):753-8

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1001/archpedi.161.8.753DOI Listing
August 2007

Predictors of diagnosis in Huntington disease.

Neurology 2007 May;68(20):1710-7

Department of Psychiatry, University of Iowa, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1212/01.wnl.0000261918.90053.96DOI Listing
May 2007

Probability of obsessive and compulsive symptoms in Huntington's disease.

Biol Psychiatry 2007 Feb 12;61(3):415-8. Epub 2006 Jul 12.

Department of Psychiatry, University of Iowa, Iowa City, Iowa 52242-1000, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.04.034DOI Listing
February 2007

Distinguishing between hypochondriasis and somatization disorder: a review of the existing literature.

Psychother Psychosom 2006 ;75(5):270-81

Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1159/000093948DOI Listing
December 2006

Association of a D2S2944 allele with depression specifically among those with substance abuse or antisocial personality.

Drug Alcohol Depend 2006 Jun 14;83(1):33-41. Epub 2005 Nov 14.

Department of Psychiatry, Psychiatry Research, Room 1-326, Medical Education Building, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2005.10.006DOI Listing
June 2006

Prevalence and correlates of illness worry in the general population.

Psychosomatics 2005 Nov-Dec;46(6):529-39

Department of Psychiatry, University of Iowa, Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1176/appi.psy.46.6.529DOI Listing
January 2006

White matter volume and cognitive dysfunction in early Huntington's disease.

Cogn Behav Neurol 2005 Jun;18(2):102-7

Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1097/01.wnn.0000152205.79033.73DOI Listing
June 2005

fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's Disease.

AJNR Am J Neuroradiol 2004 Nov-Dec;25(10):1715-21

Department of Psychiatry, University of Iowa College of Medicine, Iowa City, USA.

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February 2005

Specific phobia of illness: search for a new subtype.

J Anxiety Disord 2004 ;18(4):531-45

Department of Biostatistics, The University of Iowa Roy J. and Lucille A. Carver Colleges of Medicine and Public Health, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1016/S0887-6185(03)00041-0DOI Listing
October 2004

Test of an interpersonal model of hypochondriasis.

Psychosom Med 2003 Mar-Apr;65(2):292-300

Department of Biostatistics, University of Iowa Colleges of Medicine and Public Health, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1097/01.psy.0000058377.50240.64DOI Listing
December 2003

Genetic and environmental risk factors for the onset of drug use and problems in adoptees.

Drug Alcohol Depend 2003 Mar;69(2):151-67

Department of Psychiatry, University of Iowa, 5107 Westlawn Building, Iowa City, IA 52246, USA.

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http://dx.doi.org/10.1016/s0376-8716(02)00310-1DOI Listing
March 2003

Childhood antecedents of hypochondriasis.

Psychosomatics 2002 Jul-Aug;43(4):282-9

Department of Biostatics, University of Iowa College of Medicine, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1176/appi.psy.43.4.282DOI Listing
October 2002

Hypochondriasis and fear of death.

J Nerv Ment Dis 2002 Aug;190(8):503-9

Department of Psychiatry, University of Iowa, College of Medicine, Psychiatry Research, Medical Education Building, Iowa City 52242-1000, USA.

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http://dx.doi.org/10.1097/00005053-200208000-00002DOI Listing
August 2002