Publications by authors named "Douglas Langbehn"

98Publications

Developmental Trajectory of Height, Weight, and BMI in Children and Adolescents at Risk for Huntington's Disease: Effect of mHTT on Growth.

J Huntingtons Dis 2020 ;9(3):245-251

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.

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http://dx.doi.org/10.3233/JHD-200407DOI Listing
January 2020

Clinical Outcomes and Selection Criteria for Prodromal Huntington's Disease Trials.

Mov Disord 2020 Jul 20. Epub 2020 Jul 20.

Voyager Therapeutics, Inc., Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1002/mds.28222DOI Listing
July 2020

Behavioral inhibition and reward processing in college binge drinkers with and without marijuana use.

Drug Alcohol Depend 2020 Jun 12;213:108119. Epub 2020 Jun 12.

Department of Psychiatry, Carver College of Medicine, The University of Iowa, 200 Hawkins Dr., Iowa City, IA 52242, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2020.108119DOI Listing
June 2020

Huntington's Disease Progression: A Population Modeling Approach to Characterization Using Clinical Rating Scales.

J Clin Pharmacol 2020 Aug 16;60(8):1051-1060. Epub 2020 May 16.

Division of Pharmacometrics, Food and Drug Administration, Silver Spring, Maryland, USA.

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http://dx.doi.org/10.1002/jcph.1598DOI Listing
August 2020

Hypertension Is Associated with an Earlier Age of Onset of Huntington's Disease.

Mov Disord 2020 Apr 27. Epub 2020 Apr 27.

Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1002/mds.28062DOI Listing
April 2020

Abnormal brain development in child and adolescent carriers of mutant huntingtin.

Neurology 2019 Sep 1;93(10):e1021-e1030. Epub 2019 Aug 1.

From the Department of Psychiatry (E.v.d.P., T.R.K.), University of Iowa Hospitals & Clinics; and the Departments of Psychiatry (D.R.L., A.T., E.A.E., P.C.N.), Biostatistics (D.R.L., A.T.), and Radiology (V.A.M.) and Stead Family Department of Pediatrics (A.L.C.), University of Iowa, Iowa City.

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http://dx.doi.org/10.1212/WNL.0000000000008066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745731PMC
September 2019

Test-Retest Reliability of Measures Commonly Used to Measure Striatal Dysfunction across Multiple Testing Sessions: A Longitudinal Study.

Front Psychol 2017 12;8:2363. Epub 2018 Jan 12.

Huntington's Disease Centre, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.3389/fpsyg.2017.02363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5770367PMC
January 2018

Stimulating neural plasticity with real-time fMRI neurofeedback in Huntington's disease: A proof of concept study.

Hum Brain Mapp 2018 03 13;39(3):1339-1353. Epub 2017 Dec 13.

UCL Huntington's Disease Centre, Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/hbm.23921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838530PMC
March 2018

Motor, cognitive, and functional declines contribute to a single progressive factor in early HD.

Neurology 2017 Dec 15;89(24):2495-2502. Epub 2017 Nov 15.

From F. Hoffman-La Roche, Ltd (S.A.S., G.P., O.S.K., D.T., J.J.S.), Roche Innovation Center, Basel, Switzerland; University of Rochester (P.A., S.M., E.R.D., K.D.K.), NY; University of Iowa (J.D.L., D.R.L.), Iowa City; Massachusetts General Hospital and Harvard Medical School (M.C., S.H.), Boston; CHDI Management/Foundation (C.S.), Princeton, NJ; University of British Columbia, Vancouver, Canada (B.R.L.); and University College London (S.J.T.), UK.

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http://dx.doi.org/10.1212/WNL.0000000000004743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729794PMC
December 2017

Cortical Thickness in Adolescents with a Family History of Alcohol Use Disorder.

Alcohol Clin Exp Res 2018 Jan 6;42(1):89-99. Epub 2017 Dec 6.

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa.

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http://dx.doi.org/10.1111/acer.13543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7219278PMC
January 2018

Survival End Points for Huntington Disease Trials Prior to a Motor Diagnosis.

JAMA Neurol 2017 11;74(11):1352-1360

Huntington's Disease Centre, Department of Neurodegenerative Disease, Institute of Neurology, University College London, Queen Square, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2017.2107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710578PMC
November 2017

Polyunsaturated fatty acid composition and childhood adversity: Independent correlates of depressive symptom persistence.

Psychiatry Res 2017 10 21;256:305-311. Epub 2017 Jun 21.

Department of Psychiatry and Pediatrics, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2017.06.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193447PMC
October 2017

Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study.

Lancet Neurol 2017 09 20;16(9):701-711. Epub 2017 Jun 20.

UCL Huntington's Disease Centre, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30161-8DOI Listing
September 2017

Validation of a prognostic index for Huntington's disease.

Mov Disord 2017 02 28;32(2):256-263. Epub 2016 Nov 28.

CHDI Management/CHDI Foundation, Princeton, New Jersey, USA.

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http://dx.doi.org/10.1002/mds.26838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318276PMC
February 2017

Neuropsychiatry and White Matter Microstructure in Huntington's Disease.

J Huntingtons Dis 2015 ;4(3):239-49

Institute of Human Development, Faculty of Medical and Human Sciences, University of Manchester and Manchester Academic Health Science Centre, Manchester, UK.

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http://dx.doi.org/10.3233/JHD-150160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684097PMC
July 2016

Criteria for success in safety and tolerability trials.

Lancet Neurol 2015 Jan 14;14(1):24-5. Epub 2014 Nov 14.

Department of Psychiatry, Carver College of Medicine, Iowa City, IA, USA; Department of Biostatistics (secondary), College of Public Health, University of Iowa, Iowa City, IA, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(14)70265-0DOI Listing
January 2015

Results of the citalopram to enhance cognition in Huntington disease trial.

Mov Disord 2014 Mar 27;29(3):401-5. Epub 2013 Dec 27.

Department of Psychiatry, University of Iowa, Iowa City, Iowa, USA; Neurological program, Elks Rehab Hospital, Boise, Idaho, USA.

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http://dx.doi.org/10.1002/mds.25750DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960314PMC
March 2014

Predicting Disease Onset from Mutation Status Using Proband and Relative Data with Applications to Huntington's Disease.

J Probab Stat 2012 Jan;2012

Department of Biostatistics, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032, USA.

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http://dx.doi.org/10.1155/2012/375935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3589804PMC
January 2012

Effects of continuity of care and patient dispositional factors on the physician-patient relationship.

Ann Clin Psychiatry 2011 Aug;23(3):180-5

Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920260PMC
August 2011

Early atrophy of pallidum and accumbens nucleus in Huntington's disease.

J Neurol 2011 Mar 9;258(3):412-20. Epub 2010 Oct 9.

Department of Neurology, Leiden University Medical Center, Albinusdreef 2, 2300 RC Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00415-010-5768-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3112014PMC
March 2011

Cerebral cortex structure in prodromal Huntington disease.

Neurobiol Dis 2010 Dec 2;40(3):544-54. Epub 2010 Aug 2.

Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.nbd.2010.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955824PMC
December 2010

Challenges assessing clinical endpoints in early Huntington disease.

Mov Disord 2010 Nov;25(15):2595-603

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242-1000, USA.

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http://dx.doi.org/10.1002/mds.23337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978744PMC
November 2010

Self-paced timing detects and tracks change in prodromal Huntington disease.

Neuropsychology 2010 Jul;24(4):435-42

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1037/a0018905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900808PMC
July 2010

Earliest functional declines in Huntington disease.

Psychiatry Res 2010 Jul 15;178(2):414-8. Epub 2010 May 15.

Department of Psychiatry, The University of Iowa, Iowa City, IA, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016517811000189
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http://dx.doi.org/10.1016/j.psychres.2010.04.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629818PMC
July 2010

Striatal and white matter predictors of estimated diagnosis for Huntington disease.

Brain Res Bull 2010 May 10;82(3-4):201-7. Epub 2010 Apr 10.

University of Iowa Roy and Lucille Carver College of Medicine, Department of Psychiatry, Iowa City, IA, United States.

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http://dx.doi.org/10.1016/j.brainresbull.2010.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892238PMC
May 2010

Hypochondriacal symptoms associated with a less therapeutic physician-patient relationship.

Psychiatry 2010 ;73(1):57-69

Department of Psychiatry, College of Medicine, College of Public Health at the University of Iowa, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1521/psyc.2010.73.1.57DOI Listing
June 2010

Randomized controlled trial of atomoxetine for cognitive dysfunction in early Huntington disease.

J Clin Psychopharmacol 2009 Oct;29(5):484-7

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1097/JCP.0b013e3181b2ac0aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806326PMC
October 2009

CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches.

Am J Med Genet B Neuropsychiatr Genet 2010 Mar;153B(2):397-408

Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, Iowa.

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http://dx.doi.org/10.1002/ajmg.b.30992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048807PMC
March 2010

Normative data on and psychometric properties of Verbal and Visual Indexes of the RBANS in older adults.

Clin Neuropsychol 2009 Jan 12;23(1):39-50. Epub 2008 Mar 12.

University of Iowa, Department of Psychiatry, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1080/13854040701861391DOI Listing
January 2009

Abnormal brain structure in children with isolated clefts of the lip or palate.

Arch Pediatr Adolesc Med 2007 Aug;161(8):753-8

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1001/archpedi.161.8.753DOI Listing
August 2007

Social function in boys with cleft lip and palate: relationship to ventral frontal cortex morphology.

Behav Brain Res 2007 Aug 22;181(2):224-31. Epub 2007 Apr 22.

University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.bbr.2007.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976412PMC
August 2007

Predictors of diagnosis in Huntington disease.

Neurology 2007 May;68(20):1710-7

Department of Psychiatry, University of Iowa, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1212/01.wnl.0000261918.90053.96DOI Listing
May 2007

Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study.

Biol Psychiatry 2007 Dec 3;62(12):1341-6. Epub 2007 May 3.

Department of Psychiatry, University of Iowa, Iowa City, Iowa 52242-1000, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.11.034DOI Listing
December 2007

Incidence of delirium and associated mortality in hematopoietic stem cell transplantation patients.

Biol Blood Marrow Transplant 2006 Sep;12(9):928-35

Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa.

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http://dx.doi.org/10.1016/j.bbmt.2006.05.009DOI Listing
September 2006

Distinguishing between hypochondriasis and somatization disorder: a review of the existing literature.

Psychother Psychosom 2006 ;75(5):270-81

Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1159/000093948DOI Listing
December 2006

Probability of obsessive and compulsive symptoms in Huntington's disease.

Biol Psychiatry 2007 Feb 12;61(3):415-8. Epub 2006 Jul 12.

Department of Psychiatry, University of Iowa, Iowa City, Iowa 52242-1000, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.04.034DOI Listing
February 2007

Association of a D2S2944 allele with depression specifically among those with substance abuse or antisocial personality.

Drug Alcohol Depend 2006 Jun 14;83(1):33-41. Epub 2005 Nov 14.

Department of Psychiatry, Psychiatry Research, Room 1-326, Medical Education Building, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.drugalcdep.2005.10.006DOI Listing
June 2006

Prevalence and correlates of illness worry in the general population.

Psychosomatics 2005 Nov-Dec;46(6):529-39

Department of Psychiatry, University of Iowa, Roy J. and Lucille A. Carver College of Medicine, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1176/appi.psy.46.6.529DOI Listing
January 2006

White matter volume and cognitive dysfunction in early Huntington's disease.

Cogn Behav Neurol 2005 Jun;18(2):102-7

Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, Iowa 52242, USA.

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http://dx.doi.org/10.1097/01.wnn.0000152205.79033.73DOI Listing
June 2005

Contributions of attachment style and perceived social support to lifetime use of illicit substances.

Addict Behav 2005 Jun;30(5):1007-11

Psychiatry Research/MEB, Department of Psychiatry, College of Medicine, University of Iowa, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.addbeh.2004.09.001DOI Listing
June 2005

fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's Disease.

AJNR Am J Neuroradiol 2004 Nov-Dec;25(10):1715-21

Department of Psychiatry, University of Iowa College of Medicine, Iowa City, USA.

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February 2005

Specific phobia of illness: search for a new subtype.

J Anxiety Disord 2004 ;18(4):531-45

Department of Biostatistics, The University of Iowa Roy J. and Lucille A. Carver Colleges of Medicine and Public Health, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1016/S0887-6185(03)00041-0DOI Listing
October 2004

The association of the D2S2944 124 bp allele with recurrent early onset major depressive disorder in women.

Am J Med Genet B Neuropsychiatr Genet 2003 Aug;121B(1):39-43

Department of Psychiatry, The University of Iowa, Iowa City, Iowa 52242-1000, USA.

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http://dx.doi.org/10.1002/ajmg.b.20062DOI Listing
August 2003

Associations of the serotonin transporter promoter polymorphism with aggressivity, attention deficit, and conduct disorder in an adoptee population.

Compr Psychiatry 2003 Mar-Apr;44(2):88-101

Departments of Psychiatry and Biostatistics, and the Neuroscience Program, University of Iowa, Iowa City, IA.

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http://dx.doi.org/10.1053/comp.2003.50018DOI Listing
July 2003

Test of an interpersonal model of hypochondriasis.

Psychosom Med 2003 Mar-Apr;65(2):292-300

Department of Biostatistics, University of Iowa Colleges of Medicine and Public Health, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1097/01.psy.0000058377.50240.64DOI Listing
December 2003

Genetic and environmental risk factors for the onset of drug use and problems in adoptees.

Drug Alcohol Depend 2003 Mar;69(2):151-67

Department of Psychiatry, University of Iowa, 5107 Westlawn Building, Iowa City, IA 52246, USA.

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http://dx.doi.org/10.1016/s0376-8716(02)00310-1DOI Listing
March 2003

The association of a HOPA polymorphism with major depression and phobia.

Compr Psychiatry 2002 Sep-Oct;43(5):404-10

Department of Psychiatry, Neuroscience Program, The University of Iowa and Veterans Affairs Medical Center, Iowa City, IA 52242-1000, USA.

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http://dx.doi.org/10.1053/comp.2002.33489DOI Listing
November 2002

Hypochondriasis and fear of death.

J Nerv Ment Dis 2002 Aug;190(8):503-9

Department of Psychiatry, University of Iowa, College of Medicine, Psychiatry Research, Medical Education Building, Iowa City 52242-1000, USA.

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http://dx.doi.org/10.1097/00005053-200208000-00002DOI Listing
August 2002

Childhood antecedents of hypochondriasis.

Psychosomatics 2002 Jul-Aug;43(4):282-9

Department of Biostatics, University of Iowa College of Medicine, Iowa City, Iowa, USA.

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http://dx.doi.org/10.1176/appi.psy.43.4.282DOI Listing
October 2002