Dorothy D Sears

Dorothy D Sears

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Dorothy D Sears

Dorothy D Sears

Publications by authors named "Dorothy D Sears"

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A novel biomarker of cardiometabolic pathology in schizophrenia?

J Psychiatr Res 2019 Oct 18;117:31-37. Epub 2019 Jun 18.

Department of Psychiatry, University of California San Diego, La Jolla, CA, USA; Sam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, CA, USA; Center for Healthy Aging, University of California San Diego, La Jolla, CA, USA; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2019.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707833PMC
October 2019

Breast cancer survivors reduce accelerometer-measured sedentary time in an exercise intervention.

J Cancer Surviv 2019 Jun 29;13(3):468-476. Epub 2019 May 29.

Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, San Diego, CA, USA.

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http://dx.doi.org/10.1007/s11764-019-00768-8DOI Listing
June 2019

Association of Low Fasting Glucose and HbA1c With Cardiovascular Disease and Mortality: The MESA Study.

J Endocr Soc 2019 May 1;3(5):892-901. Epub 2019 Mar 1.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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http://dx.doi.org/10.1210/js.2019-00033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469950PMC
May 2019

Arriba por la Vida Estudio (AVE): Study protocol for a standing intervention targeting postmenopausal Latinas.

Contemp Clin Trials 2019 Apr 13;79:66-72. Epub 2019 Feb 13.

University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, United States of America.

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http://dx.doi.org/10.1016/j.cct.2019.02.004DOI Listing
April 2019

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.

Science 2019 04;364(6436)

Northwestern University, Evanston, IL, USA.

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http://dx.doi.org/10.1126/science.aau8650DOI Listing
April 2019

Modeling interrelationships between health behaviors in overweight breast cancer survivors: Applying Bayesian networks.

PLoS One 2018 4;13(9):e0202923. Epub 2018 Sep 4.

Department of Family Medicine and Public Health, University of California, San Diego, San Diego, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0202923PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122792PMC
February 2019

AIBP protects against metabolic abnormalities and atherosclerosis.

J Lipid Res 2018 05 20;59(5):854-863. Epub 2018 Mar 20.

Departments of Medicine University of California at San Diego, La Jolla, CA 92093

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http://dx.doi.org/10.1194/jlr.M083618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5928435PMC
May 2018

Metabolic Effects of Intermittent Fasting.

Annu Rev Nutr 2017 08 17;37:371-393. Epub 2017 Jul 17.

Moores Cancer Center, University of California, San Diego, La Jolla, California 92093; email:

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http://dx.doi.org/10.1146/annurev-nutr-071816-064634DOI Listing
August 2017

Kernel Density Estimation as a Measure of Environmental Exposure Related to Insulin Resistance in Breast Cancer Survivors.

Cancer Epidemiol Biomarkers Prev 2017 07 3;26(7):1078-1084. Epub 2017 Mar 3.

Department of Family Medicine and Public Health, University of California, San Diego, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-16-0927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500421PMC
July 2017

Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity.

Metabolism 2016 Dec 22;65(12):1743-1754. Epub 2016 Sep 22.

Moores Cancer Center, UC San Diego, La Jolla, CA 92093, USA; Department of Pathology, UC San Diego, La Jolla, CA 92093, USA. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2016.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123758PMC
December 2016

Circulating adipocyte-derived extracellular vesicles are novel markers of metabolic stress.

J Mol Med (Berl) 2016 11 9;94(11):1241-1253. Epub 2016 Jul 9.

Department of Pediatrics, University of California San Diego (UCSD), La Jolla, CA, 92093, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071132PMC
http://dx.doi.org/10.1007/s00109-016-1446-8DOI Listing
November 2016

Prolonged Nightly Fasting and Breast Cancer Prognosis.

JAMA Oncol 2016 Aug;2(8):1049-55

University of California, San Diego Moores Cancer Center, La Jolla3Department of Family Medicine and Public Health, University of California, San Diego, La Jolla.

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http://dx.doi.org/10.1001/jamaoncol.2016.0164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982776PMC
August 2016

Frequency and Circadian Timing of Eating May Influence Biomarkers of Inflammation and Insulin Resistance Associated with Breast Cancer Risk.

PLoS One 2015 25;10(8):e0136240. Epub 2015 Aug 25.

Moores UCSD Cancer Center, University of California San Diego, La Jolla, California, United States of America; Department of Family Medicine & Public Health, University of California San Diego, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0136240PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549297PMC
May 2016

Evaluation of the synuclein-γ (SNCG) gene as a PPARγ target in murine adipocytes, dorsal root ganglia somatosensory neurons, and human adipose tissue.

PLoS One 2015 10;10(3):e0115830. Epub 2015 Mar 10.

Graduate Group in Nutritional Biology, University of California Davis, Davis, California, United States of America; Department of Nutrition, University of California Davis, Davis, California, United States of America; Arkansas Children's Nutrition Center and Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115830PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355072PMC
January 2016

Impact of increasing physical activity on cognitive functioning in breast cancer survivors: Rationale and study design of Memory & Motion.

Contemp Clin Trials 2015 Nov 30;45(Pt B):371-376. Epub 2015 Sep 30.

Department of Family Medicine and Public Health, UC San Diego, La Jolla, CA, USA; UC San Diego Moores Cancer Center, UC San Diego, La Jolla, CA, USA; Department of Medicine, UC San Diego, La Jolla, CA, USA.

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http://dx.doi.org/10.1016/j.cct.2015.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674350PMC
November 2015

Prolonged Nightly Fasting and Breast Cancer Risk: Findings from NHANES (2009-2010).

Cancer Epidemiol Biomarkers Prev 2015 May 20;24(5):783-9. Epub 2015 Apr 20.

Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California. Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California.

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http://dx.doi.org/10.1158/1055-9965.EPI-14-1292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417458PMC
May 2015

Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress.

Mol Cell Biol 2013 Jun 9;33(12):2425-35. Epub 2013 Apr 9.

School of Biological Sciences, Institute of Molecular Biology and Genetics, National Creative Research Initiatives Center for Adipose Tissue Remodeling, Seoul National University, Seoul, South Korea.

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http://dx.doi.org/10.1128/MCB.01260-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700093PMC
June 2013

TLR4 and Insulin Resistance.

Gastroenterol Res Pract 2010 10;2010. Epub 2010 Aug 10.

Department of Pediatrics, University of California, San Diego, CA 92093-0673, USA.

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http://dx.doi.org/10.1155/2010/212563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931384PMC
July 2011

Multi-tissue, selective PPARγ modulation of insulin sensitivity and metabolic pathways in obese rats.

Am J Physiol Endocrinol Metab 2011 Jan 19;300(1):E164-74. Epub 2010 Oct 19.

Department of Bioengineering, University of California, San Diego, CA, USA.

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http://dx.doi.org/10.1152/ajpendo.00219.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023199PMC
January 2011

Fat-induced inflammation unchecked.

Cell Metab 2010 Dec;12(6):553-4

Department of Medicine, Division of Endocrinology and Metabolism, University of California, San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1016/j.cmet.2010.11.017DOI Listing
December 2010

Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice.

J Biol Chem 2010 May 22;285(20):15333-45. Epub 2010 Mar 22.

Division of Endocrinology and Metabolism, Department of Medicine, University of California, San Diego, La Jolla, California 92093-0673, USA.

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http://dx.doi.org/10.1074/jbc.M110.100263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865288PMC
May 2010

PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization.

Proc Natl Acad Sci U S A 2009 Dec 16;106(52):22504-9. Epub 2009 Dec 16.

Gene Expression Laboratory, Howard Hughes Medical Institute and The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://www.pnas.org/lookup/doi/10.1073/pnas.0912487106
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http://dx.doi.org/10.1073/pnas.0912487106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2794650PMC
December 2009

12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.

PLoS One 2009 Sep 29;4(9):e7250. Epub 2009 Sep 29.

Division of Endocrinology and Metabolism, Department of Medicine, University of California San Diego, La Jolla, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007250PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746280PMC
September 2009

FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes.

J Biol Chem 2009 May 26;284(18):12188-97. Epub 2009 Feb 26.

Division of Endocrinology-Metabolism, Department of Medicine, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1074/jbc.M808915200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673287PMC
May 2009

Selective modulation of promoter recruitment and transcriptional activity of PPARgamma.

Biochem Biophys Res Commun 2007 Dec 18;364(3):515-21. Epub 2007 Oct 18.

Department of Medicine, University of California, San Diego, 9500 Gilman Drive, MC0673, La Jolla, CA 92093, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0702183
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http://dx.doi.org/10.1016/j.bbrc.2007.10.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585742PMC
December 2007