Publications by authors named "Doris Chen"

40Publications

Long-term cocaine use is associated with increased coronary plaque burden - a pilot study.

Am J Drug Alcohol Abuse 2020 Sep 29:1-7. Epub 2020 Sep 29.

Department of Pathology, Johns Hopkins School of Medicine , Baltimore, USA.

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http://dx.doi.org/10.1080/00952990.2020.1807558DOI Listing
September 2020

RNA polymerase II-binding aptamers in human ACRO1 satellites disrupt transcription .

Transcription 2020 Jul 14:1-13. Epub 2020 Jul 14.

Department of Biochemistry and Molecular Cell Biology, Max Perutz Labs, University of Vienna , Vienna, Austria.

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http://dx.doi.org/10.1080/21541264.2020.1790990DOI Listing
July 2020

High Dietary Advanced Glycation End Products Impair Mitochondrial and Cognitive Function.

J Alzheimers Dis 2020 ;76(1):165-178

Department of Pharmacology and Toxicology and Higuchi Biosciences Center, University of Kansas, Lawrence, KS, USA.

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http://dx.doi.org/10.3233/JAD-191236DOI Listing
January 2020

Effect of Electronic Clinical Decision Support on Imaging for the Evaluation of Acute Low Back Pain in the Ambulatory Care Setting.

World Neurosurg 2020 Feb 13;134:e874-e877. Epub 2019 Nov 13.

Department of Neurosurgery, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1016/j.wneu.2019.11.031DOI Listing
February 2020

Effect of Electronic Clinical Decision Support on 25(OH) Vitamin D Testing.

J Gen Intern Med 2019 09;34(9):1697-1699

Department of Medicine, Primary Care and Population Health, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1007/s11606-019-05057-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712098PMC
September 2019

Nuclear dynamics of the Set1C subunit Spp1 prepares meiotic recombination sites for break formation.

J Cell Biol 2018 10 23;217(10):3398-3415. Epub 2018 Jul 23.

MTA-DE Momentum Genome Architecture and Recombination Research Group, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

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http://dx.doi.org/10.1083/jcb.201712122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168271PMC
October 2018

Astrocytes Attenuate Mitochondrial Dysfunctions in Human Dopaminergic Neurons Derived from iPSC.

Stem Cell Reports 2018 02 27;10(2):366-374. Epub 2018 Jan 27.

Department of Pharmacology and Toxicology, and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, 2099 Constant Avenue, Lawrence, KS 66047, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830955PMC
February 2018

RAGE mediates Aβ accumulation in a mouse model of Alzheimer's disease via modulation of β- and γ-secretase activity.

Hum Mol Genet 2018 03;27(6):1002-1014

Department of Pharmacology and Toxicology, and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, KS 66047, USA.

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http://dx.doi.org/10.1093/hmg/ddy017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075512PMC
March 2018

Development and Dynamic Regulation of Mitochondrial Network in Human Midbrain Dopaminergic Neurons Differentiated from iPSCs.

Stem Cell Reports 2016 10 22;7(4):678-692. Epub 2016 Sep 22.

Department of Pharmacology and Toxicology, Higuchi Bioscience Center, School of Pharmacy, University of Kansas, 2099 Constant Avenue, Lawrence, KS 66047, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5063542PMC
October 2016

Mfn2 is Required for Mitochondrial Development and Synapse Formation in Human Induced Pluripotent Stem Cells/hiPSC Derived Cortical Neurons.

Sci Rep 2016 08 18;6:31462. Epub 2016 Aug 18.

Department of Pharmacology and Toxicology, and Higuchi Bioscience Center, School of Pharmacology, University of Kansas, Lawrence, KS, USA.

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http://dx.doi.org/10.1038/srep31462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4989148PMC
August 2016

Base pairing and structural insights into the 5-formylcytosine in RNA duplex.

Nucleic Acids Res 2016 06 13;44(10):4968-77. Epub 2016 Apr 13.

Department of Chemistry, University at Albany, State University of New York, Albany, NY 12222, USA The RNA Institute, University at Albany, State University of New York, Albany, NY 12222, USA

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http://dx.doi.org/10.1093/nar/gkw235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4889945PMC
June 2016

Transcription dynamically patterns the meiotic chromosome-axis interface.

Elife 2015 Aug 10;4. Epub 2015 Aug 10.

Department of Biology, New York University, New York, United States.

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http://dx.doi.org/10.7554/eLife.07424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530585PMC
August 2015

Evolution of aortic wall thickness and stiffness with atherosclerosis: long-term follow up from the multi-ethnic study of atherosclerosis.

Hypertension 2015 May 16;65(5):1015-9. Epub 2015 Mar 16.

From the Department of Radiology and Imaging Sciences, National Institutes of Health (NIH), Bethesda, MD (C.-Y.L., D.A.B.); Department of Radiology, Johns Hopkins Hospital, Baltimore, MD (D.C., D.A.B., J.A.C.L.); Office of Biostatistics Research, National Heart, Lung, and Blood Institutes (NHLBI), Bethesda, MD (C.O.W.); Department of Cardiology, Hospital General Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain (G.T.-T.); Division of Cardiovascular Medicine, University of Louisville School of Medicine, KY (A.C.); and Division of Cardiovascular Medicine, Department of Internal Medicine, Wake Forest University, Winston-Salem, NC (S.V., W.G.H.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.05080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410010PMC
May 2015

Smc5/6-Mms21 prevents and eliminates inappropriate recombination intermediates in meiosis.

PLoS Genet 2013 26;9(12):e1004067. Epub 2013 Dec 26.

Max Perutz Laboratories, Chromosome Biology, University of Vienna, Vienna Biocenter, Vienna, Austria.

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http://dx.doi.org/10.1371/journal.pgen.1004067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873250PMC
August 2014

Somatic mutations of calreticulin in myeloproliferative neoplasms.

N Engl J Med 2013 Dec 10;369(25):2379-90. Epub 2013 Dec 10.

From CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (T.K., A.S.H., H.N., J.D.M., N.C.C.T., T.B., D.C., G.I.V., K.B., F.S., C.C., M. Six, A.S., C.B., G.S.-F., R.K.) and the Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna (H.G., B.G., M. Schalling, R.K.) - both in Vienna; and the Department of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo (E.R., D.P., C.M., I.C.C., E.S., V.F., C.E., L.M., C.P., M.C.), and the Department of Molecular Medicine, University of Pavia (L.M., M.C.) - both in Pavia, Italy.

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http://dx.doi.org/10.1056/NEJMoa1311347DOI Listing
December 2013

The recombinases DMC1 and RAD51 are functionally and spatially separated during meiosis in Arabidopsis.

Plant Cell 2012 May 15;24(5):2058-70. Epub 2012 May 15.

Department of Chromosome Biology, Max F. Perutz Laboratories, University of Viena, A-1030 Viena, Austria.

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http://www.plantcell.org/cgi/doi/10.1105/tpc.112.098459
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http://dx.doi.org/10.1105/tpc.112.098459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442587PMC
May 2012

RAGE is a key cellular target for Abeta-induced perturbation in Alzheimer's disease.

Front Biosci (Schol Ed) 2012 Jan 1;4:240-50. Epub 2012 Jan 1.

Department of Surgery, Physicians and Surgeons College of Columbia University, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687351PMC
http://dx.doi.org/10.2741/265DOI Listing
January 2012

Monitoring genomic sequences during SELEX using high-throughput sequencing: neutral SELEX.

PLoS One 2010 Feb 11;5(2):e9169. Epub 2010 Feb 11.

Max F Perutz Laboratories, Department of Biochemistry, University of Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009169PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820082PMC
February 2010

Genetic deficiency of Irgm1 (LRG-47) suppresses induction of experimental autoimmune encephalomyelitis by promoting apoptosis of activated CD4+ T cells.

FASEB J 2010 May 7;24(5):1583-92. Epub 2010 Jan 7.

Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and Aging, College of Physicians and Surgeons, Columbia University, 650 West 168th St., New York, NY 10032, USA.

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http://dx.doi.org/10.1096/fj.09-137323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879948PMC
May 2010

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi.

Nature 2009 Apr 12;458(7241):987-92. Epub 2009 Apr 12.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Dr Bohr-Gasse 3.

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http://dx.doi.org/10.1038/nature07936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988197PMC
April 2009

Positional cloning by fast-track SNP-mapping in Drosophila melanogaster.

Nat Protoc 2008 ;3(11):1751-65

Research Institute of Molecular Pathology, Dr Bohr-Gasse 7, A-1030 Vienna, Austria.

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http://www.nature.com/articles/nprot.2008.175
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http://dx.doi.org/10.1038/nprot.2008.175DOI Listing
January 2009

FLYSNPdb: a high-density SNP database of Drosophila melanogaster.

Nucleic Acids Res 2009 Jan 10;37(Database issue):D567-70. Epub 2008 Sep 10.

Research Institute of Molecular Pathology (IMP), Dr Bohr-Gasse 7 and Institute of Molecular Biotechnology (IMBA), Dr Bohr-Gasse 3, A-1030 Vienna, Austria.

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http://dx.doi.org/10.1093/nar/gkn583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686552PMC
January 2009

High-resolution, high-throughput SNP mapping in Drosophila melanogaster.

Nat Methods 2008 Apr 9;5(4):323-9. Epub 2008 Mar 9.

Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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http://dx.doi.org/10.1038/nmeth.1191DOI Listing
April 2008

Endophilin I expression is increased in the brains of Alzheimer disease patients.

J Biol Chem 2008 Feb 31;283(9):5685-91. Epub 2007 Dec 31.

Schools of Biology and Medicine, University of St. Andrews, Scotland KY16 9TS.

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http://dx.doi.org/10.1074/jbc.M707932200DOI Listing
February 2008

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila.

Nature 2007 Jul;448(7150):151-6

Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Dr. Bohr-Gasse 3-5, A-1030 Vienna, Austria.

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http://dx.doi.org/10.1038/nature05954DOI Listing
July 2007