Doriana Fruci

Doriana Fruci

UNVERIFIED PROFILE

Are you Doriana Fruci?   Register this Author

Register author
Doriana Fruci

Doriana Fruci

Publications by authors named "Doriana Fruci"

Are you Doriana Fruci?   Register this Author

46Publications

448Reads

17Profile Views

Peptide Trimming for MHC Class I Presentation by Endoplasmic Reticulum Aminopeptidases.

Methods Mol Biol 2019 ;1988:45-57

Immuno-Oncology Laboratory, Department of Pediatric Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-9450-2_4DOI Listing
January 2020

Influence of the Tumor Microenvironment on NK Cell Function in Solid Tumors.

Front Immunol 2019 21;10:3038. Epub 2020 Jan 21.

Paediatric Haematology/Oncology Department, Ospedale Pediatrico Bambino Gesù, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.03038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6985149PMC
January 2020

Role of genetic variations on MHC class I antigen-processing genes in human cancer and viral-mediated diseases.

Mol Immunol 2019 09 4;113:11-15. Epub 2018 Apr 4.

Immuno-Oncology Laboratory, Pediatric Haematology/Oncology Department, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2018.03.024DOI Listing
September 2019

Counter-regulation of regulatory T cells by autoreactive CD8 T cells in rheumatoid arthritis.

J Autoimmun 2019 May 16;99:81-97. Epub 2019 Feb 16.

Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, 00161, Rome, Italy; Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, 00161, Rome, Italy; Istituto Pasteur - Fondazione Cenci Bolognetti, 00185, Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2019.02.001DOI Listing
May 2019

Regulation of ERAP1 and ERAP2 genes and their disfunction in human cancer.

Hum Immunol 2019 May 27;80(5):318-324. Epub 2019 Feb 27.

Paediatric Haematology/Oncology Department, Ospedale Pediatrico Bambino Gesù, 00146 Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.humimm.2019.02.014DOI Listing
May 2019

The Role of HCMV and HIV-1 MicroRNAs: Processing, and Mechanisms of Action during Viral Infection.

Front Microbiol 2017 21;8:689. Epub 2017 Apr 21.

RNA Editing Laboratory, Oncohaematology Department, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere ScientificoRome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2017.00689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399795PMC
April 2017

Drug Transporters and Multiple Drug Resistance in Pediatric Solid Tumors.

Curr Drug Metab 2016 ;17(4):308-16

Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1567205010666131212110948DOI Listing
December 2016

Tumor-infiltrating T lymphocytes improve clinical outcome of therapy-resistant neuroblastoma.

Oncoimmunology 2015 Sep 2;4(9):e1019981. Epub 2015 Apr 2.

Paediatric Haematology/Oncology Department; IRCCS; Ospedale Pediatrico Bambino Gesù , Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/2162402X.2015.1019981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570119PMC
September 2015

Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer.

Int J Mol Sci 2012 4;13(7):8338-52. Epub 2012 Jul 4.

Paediatric Haematology/Oncology Department, Bambino Gesù Children's Hospital IRCCS, Piazza S. Onofrio 4, Rome 00165, Italy; E-Mails: (L.C.); (P.R.); (S.L.); (F.L.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms13078338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3430237PMC
August 2015

A role for naturally occurring alleles of endoplasmic reticulum aminopeptidases in tumor immunity and cancer pre-disposition.

Front Oncol 2014 19;4:363. Epub 2014 Dec 19.

Department of Paediatric Haematology/Oncology, IRCCS, Ospedale Pediatrico Bambino Gesù , Rome , Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2014.00363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271575PMC
January 2015

Multidrug resistance and cancer stem cells in neuroblastoma and hepatoblastoma.

Int J Mol Sci 2013 Dec 18;14(12):24706-25. Epub 2013 Dec 18.

Liver Research Unit, "Bambino Gesù" Children's Hospital, IRCCS, Rome 00165, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms141224706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3876137PMC
December 2013

T and NK cells: two sides of tumor immunoevasion.

J Transl Med 2013 Feb 4;11:30. Epub 2013 Feb 4.

Paediatric Haematology/Oncology Department, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant’Onofrio 4, Rome 00165, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1479-5876-11-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621684PMC
February 2013

The putative role of endoplasmic reticulum aminopeptidases in autoimmunity: insights from genomic-wide association studies.

Autoimmun Rev 2012 Dec 7;12(2):281-8. Epub 2012 May 7.

Immunology Area, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.autrev.2012.04.007DOI Listing
December 2012

Epigenetic deregulation of microRNAs in rhabdomyosarcoma and neuroblastoma and translational perspectives.

Int J Mol Sci 2012 Dec 5;13(12):16554-79. Epub 2012 Dec 5.

Department of Pediatric Hematology-Oncology, Ospedale Pediatrico Bambino Gesù, IRCCS, Piazza S. Onofrio 4, Roma 00165, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms131216554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546707PMC
December 2012

ERAAP modulation: A possible novel strategy for cancer immunotherapy?

Oncoimmunology 2012 Jan;1(1):81-82

Oncohaematology Department; IRCCS, Ospedale Pediatrico "Bambino Gesù"; Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/onci.1.1.17828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376965PMC
January 2012

HLA-E and the origin of immunogenic self HLA epitopes.

Mol Immunol 2010 May 22;47(9):1661-2; author reply 1163-4. Epub 2010 Jan 22.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molimm.2009.12.018DOI Listing
May 2010

Class I HLA folding and antigen presentation in beta 2-microglobulin-defective Daudi cells.

J Immunol 2009 Mar;182(6):3609-17

Laboratory of Immunology, Regina Elena Cancer Institute Centro della Ricerca Sperimentale, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.0802316DOI Listing
March 2009

N-linked glycosylation selectively regulates the generic folding of HLA-Cw1.

J Biol Chem 2008 Jun 17;283(24):16469-76. Epub 2008 Apr 17.

Laboratory of Immunology, Regina Elena National Cancer Research Institute, Centro della Ricerca Sperimentale, Via delle Messi d'Oro 156, 00158 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M709175200DOI Listing
June 2008

Assembly and selective "in synthesis" labeling of quenched fluorogenic protease substrates.

Anal Biochem 2006 Oct 7;357(2):194-9. Epub 2006 Aug 7.

Laboratory of Biochemistry, Regina Elena Institute CRS, 00158 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ab.2006.07.024DOI Listing
October 2006

Effect of the [CCTG]n repeat expansion on ZNF9 expression in myotonic dystrophy type II (DM2).

Biochim Biophys Acta 2006 Mar 6;1762(3):329-34. Epub 2005 Dec 6.

Department of Biopathology, Tor Vergata University, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbadis.2005.11.004DOI Listing
March 2006

Impaired assembly results in the accumulation of multiple HLA-C heavy chain folding intermediates.

J Immunol 2005 Nov;175(10):6651-8

Laboratory of Immunology, Regina Elena Cancer Institute Centro della Ricerca Sperimentale, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.175.10.6651DOI Listing
November 2005

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

Nat Immunol 2005 Jul 22;6(7):689-97. Epub 2005 May 22.

Institut National de la Sante et Recherche Médicale Unité 580, Université René Descartes Paris 5, 75015 Paris, France.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ni1208
Publisher Site
http://dx.doi.org/10.1038/ni1208DOI Listing
July 2005

Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport.

J Immunol 2003 Mar;170(6):2977-84

Institut National de la Santé et de la Recherche Médicale Unité 580, Institut Necker, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.170.6.2977DOI Listing
March 2003

Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases.

Mol Immunol 2002 Oct;39(3-4):203-15

INSERM U25, 161 Rue de Sèvres, 75743 Paris, Cedex 15, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0161-5890(02)00102-5DOI Listing
October 2002