Donna Neuberg

Donna Neuberg

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Donna Neuberg

Donna Neuberg

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Sudden death in sickle cell disease: current experience.

Br J Haematol 2020 Feb 5;188(4):e43-e45. Epub 2019 Dec 5.

Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/bjh.16314DOI Listing
February 2020

Dissecting the web of ischemic stroke, sickle cell trait, and chronic kidney disease.

Authors:
Donna Neuberg

Am J Hematol 2019 Dec 18;94(12):1302. Epub 2019 Oct 18.

Department of Data Sciences, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1002/ajh.25649DOI Listing
December 2019

Severe CD4+ T-cell lymphopenia is not observed in frequent plateletpheresis donors collected on the Fenwal Amicus.

Transfusion 2019 Sep 4;59(9):2783-2787. Epub 2019 Jul 4.

Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1111/trf.15441DOI Listing
September 2019

CD4+ T-cell lymphopenia in frequent platelet donors who have ceased platelet donation for at least 1 year.

Transfusion 2019 May 12;59(5):1644-1647. Epub 2019 Feb 12.

Hematology Division, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1111/trf.15192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6504640PMC
May 2019

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias.

Cancer Cell 2019 04;35(4):664-676.e7

Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02445, USA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6541931PMC
April 2019

Postoperative bridging anticoagulation and left ventricular assist system thrombosis.

J Thromb Thrombolysis 2019 Jan;47(1):57-66

Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1007/s11239-018-1746-7DOI Listing
January 2019

Panobinostat in combination with rituximab in heavily pretreated diffuse large B-cell lymphoma: Results of a phase II study.

Hematol Oncol 2018 Oct 28;36(4):633-637. Epub 2018 Jun 28.

Massachusetts General Hospital Cancer Center, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://doi.wiley.com/10.1002/hon.2515
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http://dx.doi.org/10.1002/hon.2515DOI Listing
October 2018

Reply to Z. Wu et al.

J Clin Oncol 2018 09 30;36(25):2657. Epub 2018 May 30.

Donna S. Neuberg, Dana-Farber Cancer Institute; and Harvard T.H. Chan School of Public Health, Boston, MA; Scott J. Rodig, Brigham and Women's Hospital, Boston, MA; and Margaret A. Shipp, Dana-Farber Cancer Institute, Boston, MA.

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http://ascopubs.org/doi/10.1200/JCO.2018.78.9826
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http://dx.doi.org/10.1200/JCO.2018.78.9826DOI Listing
September 2018

The Benefits of TRTHing along.

Hemasphere 2018 Aug 27;2(4):e138. Epub 2018 Jul 27.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1097/HS9.0000000000000138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746002PMC
August 2018

PPARγ Contributes to Immunity Induced by Cancer Cell Vaccines That Secrete GM-CSF.

Cancer Immunol Res 2018 06 18;6(6):723-732. Epub 2018 Apr 18.

Department of Medical Oncology, Dana-Farber Cancer Institute and Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0612DOI Listing
June 2018

Microbial symbionts regulate the primary Ig repertoire.

J Exp Med 2018 05 27;215(5):1397-1415. Epub 2018 Mar 27.

Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

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http://dx.doi.org/10.1084/jem.20171761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940265PMC
May 2018

Major Histocompatibility Complex Class II and Programmed Death Ligand 1 Expression Predict Outcome After Programmed Death 1 Blockade in Classic Hodgkin Lymphoma.

J Clin Oncol 2018 04 2;36(10):942-950. Epub 2018 Feb 2.

Margaretha G.M. Roemer, Robert A. Redd, Fathima Zumla Cader, Christine J. Pak, Sara Abdelrahman, Jing Ouyang, Philippe Armand, Donna S. Neuberg, and Margaret A. Shipp, Dana-Farber Cancer Institute; Geraldine S. Pinkus, Azra H. Ligon, and Scott J. Rodig, Brigham and Women's Hospital, Boston, MA; Margaretha G.M. Roemer, VU University Medical Center; Jan Paul De Boer, Antoni van Leeuwenhoek Hospital, Lunenburg Phase I/II Consortium, Amsterdam, the Netherlands; Stephanie Sasse, University Hospital of Cologne, Cologne, Germany; Anas Younes, Memorial Sloan Kettering Cancer Center, New York, NY; Michelle Fanale, University of Texas MD Anderson Cancer Center, Houston, TX; Armando Santoro, Humanitas University, Rozzano, Milan; Pier Luigi Zinzani, University of Bologna, Bologna, Italy; John Timmerman, University of California, Los Angeles Medical Center, Los Angeles, CA; Graham P. Collins, Churchill Hospital, Oxford, United Kingdom; Radhakrishnan Ramchandren, Barbara Ann Karmanos Cancer Institute, Detroit, MI; Jonathon B. Cohen, Emory University, Atlanta, GA; John Kuruvilla, Princess Margaret Cancer Centre, Toronto, Ontario, Canada; Kerry J. Savage, British Columbia Cancer Agency Center for Lymphoid Cancer, Vancouver, British Columbia, Canada; Marek Trneny, Charles University in Prague, General University Hospital in Prague, Prague, Czech Republic; Stephen Ansell, Mayo Clinic, Rochester, MN; and Kazunobu Kato, Benedetto Farsaci, and Anne Sumbul, Bristol-Myers Squibb, Princeton, NJ.

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http://dx.doi.org/10.1200/JCO.2017.77.3994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877802PMC
April 2018

Statistics Everywhere.

Authors:
Donna S Neuberg

Hemasphere 2018 Jan-Feb;2(1):e30. Epub 2018 Feb 2.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA.

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http://dx.doi.org/10.1097/HS9.0000000000000030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745945PMC
February 2018

Wrangling with P-values.

Authors:
Donna Neuberg

Pediatr Blood Cancer 2018 01 27;65(1). Epub 2017 Sep 27.

Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1002/pbc.26834DOI Listing
January 2018

Response: Making "perfect" the enemy of good.

Blood 2017 08 28;130(9):1168-1169. Epub 2017 Jul 28.

Genetics and Molecular Biology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1182/blood-2017-07-789107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5580277PMC
August 2017

How many mice? Design considerations for murine studies.

Authors:
Donna Neuberg

Blood Adv 2017 Aug 8;1(18):1466. Epub 2017 Aug 8.

Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA.

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http://dx.doi.org/10.1182/bloodadvances.2017004937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727848PMC
August 2017

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.

N Engl J Med 2017 07 21;377(2):111-121. Epub 2017 Jun 21.

From the Department of Medicine, Division of Hematology, Brigham and Women's Hospital (S.J., A.J.S., M.M.) and Harvard Medical School (B.L.E.), the Department of Medicine, Division of Cardiovascular Medicine, Brigham and Women's Hospital (E.S.) and Harvard Medical School (G.K.S., P.L.), the Department of Pathology (S.J.) and the Center for Genomic Medicine (P.N., S.K.), Massachusetts General Hospital, the Department of Medicine, Division of Cardiology, and Cardiovascular Research Center (P.N., S.K.), and the Department of Medicine (A.G.B.), Massachusetts General Hospital and Harvard Medical School, and the Departments of Medical Oncology (C.J.G.) and Biostatistics and Computational Biology (D.N.), Dana-Farber Cancer Institute, Boston, and the Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge (P.N., A.G.B., N.G., S.G., S.K.) - all in Massachusetts; the Department of Cardiology, University Hospital, Parma, Italy (D.A.); the Department of Medicine, Division of Cardiology, Mt. Sinai School of Medicine, New York (U.B., R.M., V.F.); Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid (V.F.); Medical Research Council-British Heart Foundation Cardiovascular Epidemiology Unit and National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, and the British Heart Foundation, Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge (J.D.), and the Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton (J.D.) - both in the United Kingdom; the Center for Non-Communicable Diseases, Karachi, Pakistan (P.F., D.S.); the Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia (D.S.); and the Department of Clinical Sciences Malmö, Lund University, Lund, Sweden (O.M.).

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http://dx.doi.org/10.1056/NEJMoa1701719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717509PMC
July 2017

Predicting the higher rate of intracranial hemorrhage in glioma patients receiving therapeutic enoxaparin.

Blood 2017 06 3;129(25):3379-3385. Epub 2017 May 3.

Division of Hematology and Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1182/blood-2017-02-767285DOI Listing
June 2017

Clonal Hematopoiesis Associated With Adverse Outcomes After Autologous Stem-Cell Transplantation for Lymphoma.

J Clin Oncol 2017 May 9;35(14):1598-1605. Epub 2017 Jan 9.

Christopher J. Gibson, R. Coleman Lindsley, Brenton G. Mar, Jiantao Shi, Ann S. Lacasce, Arnold S. Freedman, David C. Fisher, Eric Jacobsen, Philippe Armand, Edwin P. Alyea, John Koreth, Vincent Ho, Robert J. Soiffer, Joseph H. Antin, Jerome Ritz, Sarah Nikiforow, Franziska Michor, and Donna Neuberg, Dana-Farber Cancer Institute; Jiantao Shi and Franziska Michor, Harvard T.H. Chan School of Public Health; Siddhartha Jaiswal, Elizabeth A. Morgan, and Benjamin L. Ebert, Brigham and Women's Hospital, Boston; Benjamin L. Ebert, Broad Institute, Cambridge, MA; Vatche Tchekmedyian, Memorial Sloan Kettering Cancer Center, New York, NY; Alysia Bosworth, Anita Bansal, and Stephen J. Forman, City of Hope National Medical Center, Duarte, CA; and Liton Francisco, Jianbo He, Ravi Bhatia, and Smita Bhatia, University of Alabama at Birmingham, Birmingham, AL.

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http://dx.doi.org/10.1200/JCO.2016.71.6712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455707PMC
May 2017

Prognostic Mutations in Myelodysplastic Syndrome after Stem-Cell Transplantation.

N Engl J Med 2017 02;376(6):536-547

From the Department of Medical Oncology, Division of Hematological Malignancies (R.C.L., C.C., J.H.A.), and the Departments of Pediatric Oncology (B.G.M.) and Biostatistics and Computational Biology (R.R., D.N.), Dana-Farber Cancer Institute, and the Division of Hematology, Brigham and Women's Hospital, Harvard Medical School (P.V.G., B.L.E.) - all in Boston; the Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee (W.S., T.W., Z.-H.H., S.J.L.); the Center for International Blood and Marrow Transplant Research, National Marrow Donor Program-Be the Match (M.D.H., S.R.S.), and the Pediatric Blood and Marrow Transplantation Center, University of Minnesota (M.R.V.) - both in Minneapolis; the Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle (S.J.L.); Memorial Sloan Kettering Cancer Center, New York (K.H.); and the Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany (K.F.).

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http://dx.doi.org/10.1056/NEJMoa1611604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5438571PMC
February 2017

Protein disulfide isomerase inhibition blocks thrombin generation in humans by interfering with platelet factor V activation.

JCI Insight 2017 01 12;2(1):e89373. Epub 2017 Jan 12.

Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School.

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http://dx.doi.org/10.1172/jci.insight.89373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214567PMC
January 2017

Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.

Cancer Cell 2016 Nov 3;30(5):750-763. Epub 2016 Nov 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Dana 540, 44 Binney Street, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02141, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127278PMC
November 2016

Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage.

Proc Natl Acad Sci U S A 2016 11 14;113(48):E7701-E7709. Epub 2016 Nov 14.

Department of Genetics, Harvard Medical School, Boston, MA 02215;

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http://dx.doi.org/10.1073/pnas.1611673113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137757PMC
November 2016

Biophysical determinants for cellular uptake of hydrocarbon-stapled peptide helices.

Nat Chem Biol 2016 10 22;12(10):845-52. Epub 2016 Aug 22.

Department of Pediatric Oncology, Linde Program in Cancer Chemical Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://www.nature.com/articles/nchembio.2153
Publisher Site
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055751PMC
http://dx.doi.org/10.1038/nchembio.2153DOI Listing
October 2016

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.

Authors:
Elizabeth C Townsend Mark A Murakami Alexandra Christodoulou Amanda L Christie Johannes Köster Tiffany A DeSouza Elizabeth A Morgan Scott P Kallgren Huiyun Liu Shuo-Chieh Wu Olivia Plana Joan Montero Kristen E Stevenson Prakash Rao Raga Vadhi Michael Andreeff Philippe Armand Karen K Ballen Patrizia Barzaghi-Rinaudo Sarah Cahill Rachael A Clark Vesselina G Cooke Matthew S Davids Daniel J DeAngelo David M Dorfman Hilary Eaton Benjamin L Ebert Julia Etchin Brant Firestone David C Fisher Arnold S Freedman Ilene A Galinsky Hui Gao Jacqueline S Garcia Francine Garnache-Ottou Timothy A Graubert Alejandro Gutierrez Ensar Halilovic Marian H Harris Zachary T Herbert Steven M Horwitz Giorgio Inghirami Andrew M Intlekofer Moriko Ito Shai Izraeli Eric D Jacobsen Caron A Jacobson Sébastien Jeay Irmela Jeremias Michelle A Kelliher Raphael Koch Marina Konopleva Nadja Kopp Steven M Kornblau Andrew L Kung Thomas S Kupper Nicole R LeBoeuf Ann S LaCasce Emma Lees Loretta S Li A Thomas Look Masato Murakami Markus Muschen Donna Neuberg Samuel Y Ng Oreofe O Odejide Stuart H Orkin Rachel R Paquette Andrew E Place Justine E Roderick Jeremy A Ryan Stephen E Sallan Brent Shoji Lewis B Silverman Robert J Soiffer David P Steensma Kimberly Stegmaier Richard M Stone Jerome Tamburini Aaron R Thorner Paul van Hummelen Martha Wadleigh Marion Wiesmann Andrew P Weng Jens U Wuerthner David A Williams Bruce M Wollison Andrew A Lane Anthony Letai Monica M Bertagnolli Jerome Ritz Myles Brown Henry Long Jon C Aster Margaret A Shipp James D Griffin David M Weinstock

Cancer Cell 2016 07 11;30(1):183. Epub 2016 Jul 11.

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http://dx.doi.org/10.1016/j.ccell.2016.06.008DOI Listing
July 2016